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341
Comparatively profiling the transcriptome of human, Porcine and mouse oocytes undergoing meiotic maturation
Published 2025-03-01“…Results Transcriptome analysis identified 4,625, 3,824, 4,972 differentially expressed genes (DEGs) between the germinal vesicle (GV) and metaphase II (MII) stage in human, porcine and mouse oocytes respectively. …”
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342
Comparative transcriptomic and metabolomics analysis of ovary in Nilaparvata lugens after trehalase inhibition
Published 2025-02-01“…To investigate the mechanism by which trehalose affects the reproduction of N. lugens, we conducted a comparative transcriptomic and metabolomic analysis of the ovaries of N. lugens following injection with dsTREs and validamycin (a TRE inhibitor). …”
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343
Integrative Transcriptomic and Metabolomic Insights Into Saline-Alkali Stress Tolerance in Foxtail Millet
Published 2025-05-01“…This study examined the transcriptomic and metabolomic responses of two contrasting foxtail millet varieties, B103 (tolerant) and B323 (sensitive), under saline-alkali stress. …”
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344
Transcriptome Analysis Reveals the Requirement of the TGFβ Pathway in Ascidian Tail Regression
Published 2025-04-01“…We further investigated the downstream gene network of the TGFβ signaling pathway through comparative transcriptome data analysis on the TGFβ pathway inhibition samples. …”
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345
Comparative Transcriptome Analysis in Eggplant Reveals Selection Trends during Eggplant Domestication
Published 2019-01-01“…Taken together, our results shed light on the effects of artificial and natural selection on the transcriptomes of eggplant and its wild relatives. Identification of the selected genes will facilitate the understanding of genetic architecture of domesticated-related traits and provide resources for resistant breeding in eggplant.…”
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346
Understanding the metabolism of Mycoplasma mycoides subsp. capri in vitro by a transcriptomic analysis
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347
Whole-Transcriptome Analysis Reveals the Regulatory Network of Immune Response in Dapulian Pig
Published 2024-12-01“…Generally, the immune response is an important part of anti-disease capability; however, the related mechanism in pigs is largely puzzling. Here, the public transcriptome data of peripheral blood mononuclear cells (PBMCs) from Dapulian (Chinese local breed) and Landrace (Commercial breed) pigs after stimulation with polyinosinic-polycytidylic acid (poly I:C, a conventional reagent used for simulation of the viral infection) were reanalyzed, and the immune response mechanism in different pig breeds was investigated from a transcriptomic perspective. …”
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348
Transcriptome Differential Expression Regulation Analysis of the Narrow-Leaf Mutant of Sorghum Bicolor
Published 2025-06-01“…These genes are differentially expressed in nal6, directly affecting the signaling of auxin and zeatin and the biosynthesis of zeatin. Our findings provide a theoretical foundation for understanding the molecular regulation of narrow leaves and breeding ideal plant types in <i>Sorghum bicolor</i>.…”
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349
De novo transcriptome assembly and annotation of the semi-wild Gayal (Bos frontalis)
Published 2025-04-01“…Additionally, long non-coding RNAs (lncRNAs) were identified across all sampled tissues, and comprehensive gene expression profiles and differential expression gene analyses were performed. These findings provide a rich repository of genetic information, laying the foundation for comprehensive functional genomics studies and paving the way for deeper insights into the molecular mechanisms of the Gayal, thereby advancing our understanding of its transcriptome architecture and offering crucial data for conservation efforts and practical applications.…”
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350
Transposon insertion in pmel17 rewired skin and muscle transcriptomes in Mozambique tilapia
Published 2025-05-01“…In this study, to investigate the mechanisms underlying these phenotypic changes, we sequenced transcriptomes of the skin and muscle samples collected from wildtype and mutant tilapias. …”
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351
The full-length transcriptome analysis of blueberry under different pH conditions
Published 2025-05-01“…To understand the adaptive response of blueberry varieties to high pH, the full-length transcriptome analysis was performed with Spartan (high pH-soil-sensitive variety) and Reka (high pH-soil-tolerant variety) treated with low and high pH by hydroponics. …”
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352
Evaluation and transcriptomic and metabolomic analysis of the ability of Auricularia heimuer to utilize crop straw
Published 2025-06-01“…It was found that different metabolites were significantly enriched in starch and sucrose metabolism, glutathione metabolism, carbon metabolism and other pathways, which provided theoretical basis for efficient comprehensive utilization of corn stalk in auricularia growth.…”
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353
Transcriptome sequencing and SSR prediction of Clematis calyx based on SMRT sequencing platform
Published 2024-11-01“…Among these, the KEGG database identified 137 metabolic pathways, including biosynthesis of secondary metabolites, carbon metabolism, and amino acid biosynthesis. 104 and 7 transcripts are involved in the flavonoid and anthocyanin metabolism pathways, respectively. The above results provide initial insights into the transcriptome information and functional characteristics of Clematis calyx. …”
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354
Transcriptome and metabolite conjoint analysis reveals the seed dormancy release process of perilla
Published 2025-03-01“…The energy required for breaking seed dormancy and germination of perilla seeds is mainly provided through sucrose metabolism. Citric acid cycle (TCA cycle) is the main energy supply transformation pathway for seed germination.…”
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355
Transcriptomic and metabolomic study of the biosynthetic pathways of bioactive components in Amomum tsaoko fruits
Published 2025-02-01“…This study employed transcriptome sequencing and metabolomic analysis of A. tsaoko at five different developmental stages (May fruit – September fruit) to assess the accumulation patterns of terpenoid and curcuminoid compounds and to explore the key genes and transcription factors (TFs) involved in their synthesis pathways. …”
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356
Physiological changes and full-length transcriptome of Artemisia sphaerocephala in response to drought stress
Published 2025-05-01“…Conclusions This is the first reported large-scale sequencing of the full-length transcriptome of A. sphaerocephala under drought stress, and these results will provide a better understanding of A. sphaerocephala responses to drought stress and lay the groundwork for analysing the expression profile of genes related to drought tolerance in plants.…”
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357
Transcriptomic and Proteomic Profiling of Rabbit Kidney Cells Infected with Equine Herpesvirus 8
Published 2025-04-01“…Validation of the transcriptomic and proteomic data was performed using RT-PCR and parallel reaction monitoring (PRM), respectively, and confirmed consistent trends for TNFR1, NF-κB p65, and MAP3K8, as reported in the transcriptomic and proteomic screening. …”
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358
Multi-transcriptomics reveals niche-specific expression programs and endothelial cells in glioblastoma
Published 2025-04-01“…Methods Here, using bulk RNA sequencing, spatial transcriptomic and single cell RNA sequencing (scRNA-seq) data of GBM patients, we identified niche-specific transcriptional programs and characterized the differences in molecular expression and cellular organization between PAN and MVP. …”
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359
Transcriptomic evidence for atopic dermatitis as a systemic disease in NC/Nga mice
Published 2024-11-01“…Given the importance of evidence-based medicine and the development of precision medicine, our findings provide insights into the mechanisms of AD onset and progression.…”
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360
Transcriptome Insights into Carbohydrate Metabolism and Frying Quality Traits in Waxy and Mealy Potatoes
Published 2025-06-01“…These transcription factors are responsive to abscisic acid, a key hormonal regulator involved in tuber development. This study provides transcriptomic insights for processing quality improvement and identifies key candidate genes for marker-assisted breeding. …”
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