-
3061
Identification and expression pattern analysis of the C2H2 family in the whole genome of Agaricus bisporus
Published 2025-07-01“…Quantitative PCR validation further substantiated the transcriptome data, confirming the pivotal role of the AbC2H2 family in regulating the growth and developmental pathways in Agaricus bisporus. …”
Get full text
Article -
3062
Identification and expression analysis of PAL genes related to chlorogenic acid synthesis in Vaccinium dunalianum Wight
Published 2025-05-01“…In this study, seven PAL genes (VdPAL1–VdPAL7) were cloned and analyzed through full-length transcriptome sequencing combined with reverse transcription polymerase chain reaction (RT-PCR) amplification in V. dunalianum. …”
Get full text
Article -
3063
Genome-wide characterization and expression profiling of MADS-box family genes during organ development and drought stress in Camelina sativa L
Published 2025-03-01“…The detailed annotation and comprehensive transcriptome profiling provided in this research yield essential insights into the functional roles that MADS-box genes perform in stress resistance, as well as their contributions to growth and developmental processes. …”
Get full text
Article -
3064
Radiogenomic analysis of clinical and ultrasonic characteristics in correlation to immune-related genes in breast cancer
Published 2025-05-01“…Further analysis of these genes provides new ideas for the diagnosis and treatment of breast cancer.…”
Get full text
Article -
3065
Genome-wide identification of invertase genes in sweetpotato and its response to nitrogen and planting densities
Published 2025-03-01“…Conclusion These observations underscore the expansion of IbINVs in sweetpotato and provide a theoretical basis for optimizing the interaction between nitrogen application and planting density in sweetpotato, allowing for more efficient nitrogen use and improved growth.…”
Get full text
Article -
3066
The study on cuproptosis in Alzheimer’s disease based on the cuproptosis key gene FDX1
Published 2024-12-01“…Previous studies have shown neuronal death in the brains of AD patients, but the role of cuproptosis and its associated genes in AD neurons remains unclear.MethodsIntersection analysis was conducted using the AD transcriptome dataset GSE63060, neuron dataset GSE147528, and reported cuproptosis-related genes to identify the cuproptosis key gene FDX1 highly expressed in AD. …”
Get full text
Article -
3067
The origin and evolution of cultivated rice and genomic signatures of heterosis for yield traits in super-hybrid rice
Published 2025-06-01“…Conclusions Our study provides robust evidence for the independent domestication of indica and japonica rice subspecies and elucidates the genomic features associated with heterosis in super-hybrid rice. …”
Get full text
Article -
3068
Dietary protein/lipid ratio affects the growth performance and one-carbon metabolism mediated by folate in juvenile razor clam Sinonovacula constricta
Published 2025-04-01“…The lipid level of clam exhibited an upward trend as the dietary protein/lipid ratio decreased, and the appropriate protein/lipid ratio enhanced the activities of amylase, catalase, and superoxide dismutase. Transcriptome analysis showed that the pyrimidine/purine metabolism and one carbon pool by folate in the clam fed P41L6 diet was downregulated relative to those fed P34L10 and P27L14 diets. …”
Get full text
Article -
3069
Enhancing ovarian cancer prognosis with an artificial intelligence-derived model: Multi-omics integration and therapeutic implications
Published 2025-09-01“…The model's performance and biological insights provide a foundation for advancing precision medicine in ovarian cancer. …”
Get full text
Article -
3070
A miR-JL-5 inhibitor modulates the proliferation of Nosema ceranae in Apis cerana
Published 2025-06-01“…Our results provide insights into role that microRNA regulates the proliferation of N. ceranae in Apis cerana.…”
Get full text
Article -
3071
Detection of favorable QTL alleles and candidate genes for high pH tolerance in Chinese shrimp Fenneropenaeus chinensis via association and linkage maps
Published 2025-04-01“…By integrating with transcriptome data and functional annotations, we further verified four candidate genes: TCPG, TMEM9, PSA7, and ZNF773. …”
Get full text
Article -
3072
Echinococcus granulosus sensu lato promotes osteoclast differentiation through DUSP4-MAPK signaling in osseous echinococcosis
Published 2025-03-01“…Osteoclast differentiation and bone resorption were assessed using TRAP staining and F-actin immunofluorescence. Transcriptome sequencing identified DUSP4 as a key regulator. …”
Get full text
Article -
3073
Investigation of the Effects of Salinity Exposure on Immune Defense, Morphology, and Gene Expression in the Gills of <i>Macrobrachium nipponense</i>
Published 2025-05-01“…In addition, we found no obvious morphological changes in the gills, indicating that <i>M. nipponense</i> can adapt well to water environments with such salinity. Transcriptome profiling analysis identified 168, 434, and 944 differentially expressed genes (DEGs) when comparing S0 vs. …”
Get full text
Article -
3074
Genome-Wide Identification of <i>UGT</i> Genes and Analysis of Their Expression Profiles During Fruit Development in Walnut (<i>Juglans regia</i> L.)
Published 2024-10-01“…In conjunction with transcriptome analysis and quantitative expression, approximately 39% of <i>UGT</i> genes in walnut exhibited high expression levels during early fruit development. …”
Get full text
Article -
3075
Prognostic risk model of six m7 g-related lncRNAs in lung adenocarcinoma
Published 2025-06-01“…This study aimed to explore the prognostic value of an m7G-related lncRNAs model in LUAD. Methods Transcriptome and clinical data of LUAD patients were downloaded from the TCGA database. …”
Get full text
Article -
3076
Synergistic effects of 5-fluorouracil in combination with salinomycin promoted ferroptosis via inhibiting SLC7A11/GPX4 in colorectal cancer
Published 2025-06-01“…Wound healing and migration and invasion experiments were used to identify changes in migration and invasion capabilities under the influence of different drugs. Transcriptome sequencing is used to explore the molecular mechanisms of drugs. …”
Get full text
Article -
3077
DTC-m6Am: A Framework for Recognizing N6,2′-O-dimethyladenosine Sites in Unbalanced Classification Patterns Based on DenseNet and Attention Mechanisms
Published 2025-04-01“…In this study, we present a robust and reliable deep learning model, DTC-m6Am, for identifying m6Am sites across the transcriptome. …”
Get full text
Article -
3078
Identification and analysis of major latex protein (MLP) family genes in Rosa chinensis responsive to Botrytis cinerea infection by RNA-seq approaches
Published 2024-12-01“…In summary, our research results underscore the potential importance of the RcMLP gene family in response to B. cinerea infection and provide comprehensive basis for further function exploration of the MLP gene family in rose resistance to fungal infections.…”
Get full text
Article -
3079
Viral-mediated knockdown of Atxn2 attenuates TDP-43 pathology and muscle dysfunction in the PFN1C71G ALS mouse model
Published 2025-05-01“…Notably, impaired regulation of the PFN1C71G skeletal muscle transcriptome exceeds that of the spinal cord and is also improved by Atxn2 reduction in the CNS. …”
Get full text
Article -
3080
CNGC20 plays dual roles in regulating plant growth and immunity in Brassica napus
Published 2024-12-01“…The enhanced immunity improves the resistance to Leptosphaeria biglobosa and Sclerotinia sclerotiorum. Transcriptome analysis further revealed that CNGC20 plays dual roles in regulating plant growth and immunity via the brassinosteroid and auxin signaling pathways. …”
Get full text
Article