Analysis of the response to high temperature stress in hybrid grouper (Epinephelus fuscoguttatus♀×E. lanceolatus♂) by Yan Hu, Yafeng Tan, Junchi Liu, Haizhan Tang, Kaiwang Wang, Feng Tang, Jian Luo, Xin Wen

“…Through controlled temperature experiments, we measured the physiological and biochemical parameters of serum (ACP, AKP, TG, COR) and liver (HSP70, HSP90, SOD, CAT) in Hulong hybrid grouper and their parents, followed by liver transcriptome analysis of the three grouper species. …”
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Bioinformatics and expression analysis of heat shock protein genes in Trametes gibbosa by YANG Xuxin, FENG Lianrong, CHI Yujie, HAN Shuying

“…The above results can provide a theoretical basis for the study of T. gibbosa under stress.…”
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Global changes in gene expression of Barrett's esophagus compared to normal squamous esophagus and gastric cardia tissues. by Paula L Hyland, Nan Hu, Melissa Rotunno, Hua Su, Chaoyu Wang, Lemin Wang, Ruth M Pfeiffer, Barbara Gherman, Carol Giffen, Cathy Dykes, Sanford M Dawsey, Christian C Abnet, Kathryn M Johnson, Ruben D Acosta, Patrick E Young, Brooks D Cash, Philip R Taylor

“…<h4>Conclusion</h4>Our findings provide additional data on the global transcriptome in BE tissues compared to matched NE and NC tissues which should promote further understanding of the functions and regulatory mechanisms of genes involved in BE development, as well as insight into novel genes that may be useful as potential biomarkers for the diagnosis of BE in the future.…”
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In vitro and in vivo study on the effects of nutritive media compared with water on the resuscitation of a live attenuated Salmonella Typhimurium vaccine by Siyuan Jia, Andrea R. McWhorter, Samiullah Khan, Daniel M. Andrews, Gregory J. Underwood, Kapil K. Chousalkar

“…Overall, the findings support the use of nutritive media for the reconstitution of Vaxsafe ST, warranting further investigation to optimize vaccine performance. This study provides a foundation for future work on vaccine reconstitution strategies.…”
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Improved CAR internalization and recycling through transmembrane domain optimization reduces CAR-T cytokine release and exhaustion by Shufeng Xie, Shufeng Xie, Jinlan Long, Ruiheng Wang, Ruiheng Wang, Rufang Xiang, Rufang Xiang, Huajian Xian, Yixin Wang, Weiyu Dou, Wenjie Zhang, Dan Li, Ting Kang, Zhihong Chen, Zhihong Chen, Chunjun Zhao, Zhenshu Xu, Han Liu

“…An optimized transmembrane domain can alleviate cytokine release syndrome and reduce CAR-T cell exhaustion, providing a direction for CAR design to enhance CAR-T cell function.…”
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Diurnal dynamics of different circadian transcription modules in Chinese pine needles and roots during dormancy induction by Junhe Yang, Kai Qu, Huili Wang, Yousry A. El-Kassaby, Wei Li

“….), we identified key time nodes for dormancy initiation in autumn. To provide insight of the diurnal transcriptome dynamic in needles and roots during dormancy introduction, RNA-seq was performed at 12 consecutive time points in 24 h under natural environment in P. tabuliformis. …”
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Single-cell RNA sequencing advances in revealing the development and progression of MASH: the identifications and interactions of non-parenchymal cells by Meng Ning, Meng Ning, Meng Ning, Donghui Lu, Dong Liang, Pei-Gen Ren, Pei-Gen Ren

“…In this review, we discussed how the use of single-cell transcriptomic sequencing provided us with an in-depth understanding of the heterogeneous, cellular interactions among non-parenchymal cells and tried to highlight recent discoveries in MASH by this technology. …”
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Advanced strategies for screening and identifying RNA-targeted small molecules: Bridging therapeutic potential and innovation by Zukela Ruzi, Daxiong Han, Kailibinuer Aierken

“…By integrating cutting-edge technologies and multidisciplinary approaches, this review provides insights into current advances and future directions in RNA-targeted drug discovery.…”
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Sub-telomere directed gene expression during initiation of invasive aspergillosis. by Andrew McDonagh, Natalie D Fedorova, Jonathan Crabtree, Yan Yu, Stanley Kim, Dan Chen, Omar Loss, Timothy Cairns, Gustavo Goldman, Darius Armstrong-James, Ken Haynes, Hubertus Haas, Markus Schrettl, Gregory May, William C Nierman, Elaine Bignell

“…Recent genome sequencing of several Aspergillus species provides an exceptional opportunity to analyse fungal virulence attributes within a genomic and evolutionary context. …”
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Machine learning-random forest model was used to construct gene signature associated with cuproptosis to predict the prognosis of gastric cancer by Xiaolong Liu, Pengxian Tao, He Su, Yulan Li

“…The purpose of the present study was to establish a prognostic model of CRGs and provide directions for the diagnosis and treatment of GC. …”
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Nanostructured organic sheets sequestering small extracellular vesicles and reactive species to protect against radiation-induced mucositis by Yuefei Zhu, Changyi Xu, Zhixin Li, Xiaomin Bao, Ming Liu, Yangyang She, Renqiang Ma, Xiangzhen Liu, Jian Li, Weiping Wen, Kam W. Leong, Zhaoxu Tu

“…Flow cytometry and transcriptome analyses in irradiated animal models confirm significant mucositis mitigation. …”
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TRAF6 Promotes Gastric Cancer Cell Self-Renewal, Proliferation, and Migration by Mengting Yang, Meng Jin, Kailong Li, Haifeng Liu, Xiaxia Yang, Xiaobei Zhang, Bin Zhang, Aihua Gong, Qingli Bie

“…In conclusion, TRAF6 is a significant factor promoting proliferation and migration in gastric cancer cells and may provide a new target for the accurate treatment of gastric cancer.…”
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A differential requirement for ciliary transition zone proteins in human and mouse neural progenitor fate specification by Antonia Wiegering, Isabelle Anselme, Ludovica Brunetti, Laura Metayer-Derout, Damelys Calderon, Sophie Thomas, Stéphane Nedelec, Alexis Eschstruth, Valentina Serpieri, Martin Catala, Christophe Antoniewski, Sylvie Schneider-Maunoury, Aline Stedman

“…These findings provide important insights into the role of cilia in human neural development.…”
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Calcium chloride connects potato greening and enzymatic browning through salicylic acid by Jingkui Shi, Wenxin Xie, Yanmei Sun, Qingyu Shi, Xin Xing, Qingguo Wang, Qingqing Li

“…In this research, we conducted transcriptome analysis of non-greening and greening potatoes, identifying several browning-related genes (polyphenol oxidase genes and peroxidase genes). …”
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Paeoniflorin Inhibits Porcine Circovirus Type 2 Replication by Inhibiting Autophagy and Targeting AKT/mTOR Signaling by Zhengchang Wu, Luchen Yu, Yueqing Hu, Wenbin Bao, Shenglong Wu

“…Subsequently, comparative transcriptome and functional verification revealed that PF probably inherits PCV2 replication via targeting AKT/mTOR signaling. …”
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Unraveling the regulatory network of barley grain metabolism through the integrative analysis of multiomics and mQTL by Ruilian Song, Yixiang Wang, Yanjun Li, Qifei Wang, Siyu Zhang, Dongfa Sun, Genlou Sun, Longqing Sun, Xifeng Ren

“…Our findings reveal the metabolic regulatory network of barley grains development, and provide valuable resources for future nutritional quality improvement and molecular design breeding of barley.…”
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3D culture inhibits replicative senescence of SCAPs via UQCRC2-mediated mitochondrial oxidative phosphorylation by Yijia Shi, Tong Xiao, Yingying Weng, Ya Xiao, Jintao Wu, Jing Wang, Wenmin Wang, Maoshen Yan, Ming Yan, Zehan Li, Jinhua Yu

“…It was observed that 3D culture conditions can delay cellular senescence, potentially due to changes in mitochondrial function and oxidative phosphorylation. Transcriptome high-throughput sequencing technology revealed that the different mitochondrial states may be related to UQCRC2. …”
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Single-cell RNA-seq analysis of cancer-endothelial cell interactions in primary tumor and peritoneal metastasis from a single patient with colorectal cancer by Yuri Sakimoto, Kohei Kumegawa, Shimpei Matsui, Tomohiro Yamaguchi, Toshiki Mukai, Koji Okabayashi, Seiichi Mori, Yuko Kitagawa, Takashi Akiyoshi, Reo Maruyama

“…Methods To explore these aspects, we performed single-cell transcriptome analysis of matched primary tumor and peritoneal metastasis samples from a treatment-naïve patient. …”
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Discovery of 4,5,6,7-Tetrahydrothieno [3,2-b] Pyridine as Novel Fungicide Lead Scaffold by Ke Chen, Difan Deng, Yupeng Yin, Dongmei Xi, Phumbum Park, Wei Gao, Rui Liu, Kang Lei

“…The present work demonstrates that 4,5,6,7-tetrahydrothieno [3,2-b] pyridine represents a promising lead scaffold and provides important theoretical foundations and innovative perspectives for the development of novel and highly efficient fungicides.…”
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Reaction Mechanism of Aluminum Toxicity on Leaf Growth of Shatian Pomelo Seedlings by Dan Tan, Jingfu Yan, Yali Yang, Shaoxia Yang, Lubin Zhang, Yingbin Xue, Ying Liu

“…Leaf phenotype analysis, physiological response index determination, transcriptome analysis, and genome verification were employed to investigate the effects of Al toxicity in detail. …”
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