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2641
RNA-seq analysis of host and viral gene expression highlights interaction between varicella zoster virus and keratinocyte differentiation.
Published 2014-01-01“…At the same time, analysis of the viral transcriptome provided evidence that VZV gene expression was significantly increased following calcium treatment of keratinocytes. …”
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2642
Hypoxia‐Driven Neurovascular Impairment Underlies Structural‐Functional Dissociation in Diabetic Sudomotor Dysfunction
Published 2025-05-01“…In addition, histological staining and tissue clearing techniques provided evidence of impaired neurovascular networks adjacent to SGs. …”
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2643
Leucine-rich pentatricopeptide repeat-containing protein (LRPPRC)-stabilized lncRNA small nucleolar RNA host gene 15 (Snhg15) modulates hematopoietic injury induced by γ-ray irradi...
Published 2025-06-01“…LncRNA Snhg15 was identified as a key regulator through integration analysis of the methylome and transcriptome data. Its m6A modification was closely related to progression of radiation injury in BMCs. …”
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2644
Transgenerational inheritance of diabetes susceptibility in male offspring with maternal androgen exposure
Published 2025-02-01“…Our findings highlight the transgenerational inheritance of impaired glucose homeostasis in male offspring from maternal AE via DNA methylation changes, providing methylation biomarkers and therapeutic strategies to safeguard future generations’ metabolic health.…”
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2645
Bridging the Gap: Biofilm-mediated establishment of Bacillus velezensis on Trichoderma guizhouense mycelia
Published 2024-12-01“…These intricate biofilm-mediated BFI dynamics might contribute to the remarkable diversity observed within soil microbiota, providing a fresh perspective for further exploration of BFIs in the plant rhizosphere.…”
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2646
Identification and predictive machine learning models construction of gut microbiota associated with lymph node metastasis in colorectal cancer
Published 2025-08-01“…Furthermore, using transcriptome data from 23 CRC patients, we constructed an immune cell infiltration matrix to deeply explore the biological functions associated with LNM. …”
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2647
Fission Yeast CSL Transcription Factors: Mapping Their Target Genes and Biological Roles.
Published 2015-01-01“…<h4>Conclusions/significance</h4>Our results provide a framework for a more detailed understanding of the role of CSL proteins in the regulation of cell-cycle progression in fission yeast.…”
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2648
Genome-wide landscape of miRNA-mRNA-lncRNA-circRNA ceRNA network in Nanos2 deficient mice.
Published 2025-01-01“…To identify the probable ceRNA regulator involved in the process of spermatogenesis by Nanos2, whole transcriptome sequencing was performed in the testes between Nanos2 knock out mice and wild type mice. …”
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2649
Identification of key genes associated with anthracnose resistance in Camellia sinensis.
Published 2025-01-01“…Using the 'Longjing 43' reference genome, transcriptome assembly achieved 93.9% gene detection rate (31,509/33,557 genes). …”
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2650
Chromosome-level phased genome assembly of the argan tree Sideroxylon spinosum
Published 2025-08-01“…This high-quality assembly provides a valuable resource for future research on argan biology, genetic diversity, and traits relevant to adaptation and oil biosynthesis.…”
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2651
RES complex is associated with intron definition and required for zebrafish early embryogenesis.
Published 2018-07-01“…Pre-mRNA splicing is a critical step of gene expression in eukaryotes. Transcriptome-wide splicing patterns are complex and primarily regulated by a diverse set of recognition elements and associated RNA-binding proteins. …”
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2652
Expression of a pheromone binding protein affected by timeless gene governs female mating behavior in Bactrocera dorsalis
Published 2025-02-01“…Behavioral and electrophysiological assays revealed a peak in both mating behavior and response to sex pheromones in the evening in females. Comparative transcriptome analysis of female heads demonstrated rhythmic expression of the Timeless gene-Tim and odorant binding protein gene-Pbp5, with the highest expression levels occurring in the evening. …”
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2653
Chromosome–level genome assembly of the seasonally polyphenic scorpionfly (Panorpa liui)
Published 2025-01-01“…The high-quality genome provides critical genomic resources for population genetics and phylogenetic research on Mecoptera. …”
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2654
Phase-specific transcriptional patterns of the oomycete pathogen Phytophthora sojae unravel genes essential for asexual development and pathogenic processes.
Published 2023-03-01“…Thus, these findings provide a foundation for further gene functional annotation in oomycetes and crop disease management.…”
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2655
Emergence of carbapenem resistance in persistent Shewanella algae bacteremia: the role of pdsS G547W mutation in adaptive subpopulation dynamics
Published 2024-11-01“…Intriguingly, we observed a recurrent switch between wild-type and G547W alleles, revealing an adaptive expansion and contraction of underlying cell subpopulations in response to β-lactam exposure. Comparative transcriptome analyses further demonstrated the overexpression of genes pivotal for membrane integrity, biofilm formation, immune evasion, and β-lactamase activation in resistant samples. …”
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2656
Single-molecule direct RNA sequencing reveals the shaping of epitranscriptome across multiple species
Published 2025-06-01“…Yet, fully characterizing its transcriptome-wide landscape and biogenesis mechanisms remains challenging. …”
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2657
Evaluating the sustainable cultivation of 'Fuji' apples: suitable crop load and the impact of chemical thinning agents on fruit quality and transcription
Published 2024-01-01“…The optimal load capacity provides sustainable production and high quality in 'Fuji' apple production. …”
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2658
Probing host pathogen cross-talk by transcriptional profiling of both Mycobacterium tuberculosis and infected human dendritic cells and macrophages.
Published 2008-01-01“…<h4>Conclusions/significance</h4>This study provides the proof of principle that probing the host and the microbe transcriptomes simultaneously is a valuable means to accessing unique information on host pathogen interactions. …”
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2659
Brain-derived exosomal hemoglobin transfer contributes to neuronal mitochondrial homeostasis under hypoxia
Published 2025-06-01“…This study conducted combined analyses of single-nucleus transcriptome sequencing and extracellular vesicle transcriptome sequencing on hypoxic mouse brains, described cell–cell communication in the brain under hypoxia from intercellular and extracellular dimensions, confirmed that hemoglobin mRNA was transferred from non-neuronal cells to neurons, and eventually expressed. …”
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2660
RNA modification gene WDR4 facilitates tumor progression and immunotherapy resistance in breast cancer
Published 2025-06-01“…Alterations of tumor immune microenvironment and therapy response featured by different RMscore levels were assessed by bulk transcriptome, single-cell transcriptome and genomics analyses. …”
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