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  1. 2461

    Lack of nAChR activity depresses cochlear maturation and up-regulates GABA system components: temporal profiling of gene expression in alpha9 null mice. by Sevin Turcan, Donna K Slonim, Douglas E Vetter

    Published 2010-02-01
    “…Time-series analysis of whole transcriptome patterns, represented as self-organizing maps, revealed a disparate pattern of gene expression between alpha9(-/-) and wild type cochleae at the onset of hearing (P13), with knockout samples resembling immature postnatal ages.…”
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    Article
  2. 2462

    COVID-19 related epigenetic changes and atopic dermatitis: An exploratory analysis by Zhenwei Tang, MD, Yu Chen, MBBS, Yuzhen Ouyang, MBBS, Yu Peng, MD, PhD, Xiaoyong Man, MD, PhD

    Published 2025-01-01
    “…Methods: We combined Mendelian randomization and transcriptome analysis for data-driven explorations. …”
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    Article
  3. 2463

    Genome-wide identification of the phosphofructokinase gene family in maize (Zea mays L.) and their expression levels under abiotic stress and phytohormones by Weichao Fu, Delong Fan, Shenkui Liu, Yuanyuan Bu

    Published 2025-07-01
    “…We identified the ZmPFK genes involved in stress and plant hormone response by combining promoter element analysis, transcriptome data, and RT-qPCR analysis. This study provides valuable insights into the involvement of maize glycolysis in stress response.…”
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  4. 2464

    Viral IL-10 can promote the proliferation, migration and invasion of nasopharyngeal carcinoma cells and inhibit their apoptosis by Qin Qiu, Xingyu Yang, Xiaojiang Li, Yanxin Ren, Ning Huang

    Published 2025-02-01
    “…The purpose of this study was to provide a theoretical basis for potential targets and mechanisms of vIL-10 in nasopharyngeal carcinoma. …”
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    Article
  5. 2465

    Distinct effects of two dominant enteric bacteria on the developmental performance of Spodoptera frugiperda and their association with physiological metabolism by Wendou Fu, Peng Wang, Peicong He, Dong Chu

    Published 2025-03-01
    “…For instance, the downregulation of UDP-glycosyltransferase (UGT) and amino acid genes is closely associated with the growth and development of Spodoptera frugiperda.These findings provide deeper insights into its impact on the growth and development of S. frugiperda.…”
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  6. 2466

    Transcriptional analysis of Camellia Huana under low-phosphorus stress by Fan Wu, Lang Xia, Xin Xie, Yue Zhang, Biyin Pan

    Published 2025-05-01
    “…Abstract The molecular mechanism underlying the response of C. huana to low-phosphorus (P) stress was explored with transcriptome sequencing to analyze the genome-wide responses of plants exposed to different durations of low-P stress. …”
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  7. 2467

    Cis-regulation analysis of RNA m6A methylation and gene expression in colorectal cancer by Zhen-Liang Lin, Pan-Pan Yu, Bei-Lei Ye

    Published 2025-08-01
    “…Moreover, 34 genes showing strong correlations (r2 ≥ 0.9) were identified, including 16 genes previously reported to be associated with CRC. This study provides a transcriptome-wide strategy for quantifying the association between RNA methylation and gene expression in CRC, offering new insights into the potential regulatory roles of RNA methylation in tumor biology.…”
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    Article
  8. 2468

    In silico screening of differentially expressed genes influenced by AFAP1-AS1 in lung adenocarcinoma by Zohreh Jahanafrooz, Mahsa Tooshi

    Published 2025-09-01
    “…Dysregulation of lncRNAs has an essential impact on the transcriptome, influencing cellular functions and behaviors. …”
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    Article
  9. 2469

    Integrated analysis of physiological responses and transcriptional regulation in kiwifruit under high temperature by Jiale Tang, Hai Xu, Ping Yuan, Kejia He, Mengjie Chen, Fanwen Bu, Rencai Wang, Feixiong Luo

    Published 2025-07-01
    “…Taken together, our results provide a dependable and useful information on the heat response in kiwifruit plants.…”
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  10. 2470

    IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection. by Xiang Ye Liu, Jose de la Fuente, Martine Cote, Ruth C Galindo, Sara Moutailler, Muriel Vayssier-Taussat, Sarah I Bonnet

    Published 2014-07-01
    “…IrSPI silencing impaired tick feeding, as well as resulted in reduced bacterial load in tick SGs. This study provides a comprehensive analysis of I. ricinus SG transcriptome and contributes significant genomic information about this important disease vector. …”
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    Article
  11. 2471

    Effects of silencing StSOBIR1-like gene on potato in response to herbivory by HE Wenjing, ZHANG Yadong, ZHANG Chao, ZHONG Jian, CHEN Chuzhen, GE Yang, HE Shuyan, ZHU Zengrong, ZHOU Wenwu

    Published 2024-08-01
    “…After that, a bioassay of the potato tuber moth (Phthorimaea operculella) and the transcriptome sequencing were carried out with these plants to investigate the influence of silencing StSOBIR1-like gene on the potato defense response to the potato tuber moth. …”
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  12. 2472

    Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses by Zhiwei Wang, Aimen Shafique, Bofeng Yu, Badr Alharthi, Naushad Ali, Muhammad Salman Mubarik, Hafiz Saeed ur Rehman, Rashid Iqbal, Farrukh Azeem, Hongxing Xu

    Published 2024-12-01
    “…Bread wheat (Triticum aestivum) is a vital global staple food, providing 30 % of the world's caloric intake and nutritional needs. …”
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  13. 2473

    Antimicrobial dual-crosslinked hydrogel synergizes bioengineered extracellular vesicles for enhanced diabetic wound healing by Yikun Ju, Pu Yang, Xiangjun Liu, Rui Wu, Naisi Shen, Naihsin Hsiung, Anqi Yang, Chi Zhang, Bairong Fang, Liangle Liu

    Published 2025-06-01
    “…Antimicrobial hydrogel dressings combined with bioengineered EVs, will provide a good solution to the problem of difficult healing of diabetic wounds. …”
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    Article
  14. 2474

    Gene co-expression network and differential expression analyses reveal key genes for weaning weight in Simmental-Holstein crossbred cattle by Saina Yan, Fen Pei, Jingfnag Si, Md. Yousuf Ali Khan, Sihai Ou, Yang Yang, Zongsheng Zhao, Alfredo Pauciullo, Yi Zhang

    Published 2024-12-01
    “…In conclusion, this study reveals new candidate genes significantly associated with weaning weight in Simmental-Holstein crossbred cattle, providing a basis for further exploration of the genetic mechanisms behind growth traits of cattle.…”
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  15. 2475

    The symbiont Wolbachia increases resistance to bifenthrin in Ectropis grisescens by regulating the host detoxification function by Tian Gao, Yong Zhang, Wanpeng Sun, Qiangkun Li, Xueyu Huang, Dian Zhi, Huabin Zi, Ruijie Ji, Yanhua Long, Chunmei Gong, Yunqiu Yang

    Published 2025-01-01
    “…These results suggest that Wolbachia may contribute to the resistance of E. grisescens to bifenthrin by regulating cytochrome P450 genes, providing a foundation for further study on the mechanism of symbiont-mediated host detoxification metabolism in insect pests.…”
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  16. 2476

    The translatome of glioblastoma by Fleur M. G. Cornelissen, Zhaoren He, Edward Ciputra, Richard R. deHaas, Ammarina Beumer‐Chuwonpad, David Noske, W. Peter Vandertop, Sander R. Piersma, Connie R. Jiménez, Cornelis Murre, Bart A. Westerman

    Published 2025-03-01
    “…Our findings demonstrate that ribosome sequencing provides more detailed information than MS or transcriptional analyses. …”
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  17. 2477

    Characterization, Expression Profile Analysis, and Functional Prediction of <i>UGP</i> Gene Family in <i>Dendrocalamus brandisii</i> by He Li, Chongyang Wu, Xiangyi Li, Junlei Xu, Zhanchao Cheng, Jian Gao

    Published 2025-05-01
    “…This study suggests that the evolutionarily conserved <i>DbUGPs</i> exhibit mutual coordination and dynamic expression during <i>D. brandisii</i> growth, providing fresh insights into their functional roles.…”
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  18. 2478

    Histopathological and Transcriptional Changes in Silkworm Larval Gonads in Response to Chlorfenapyr Exposure by Tao Li, Changxiong Hu, Zenghu Liu, Qiongyan Li, Yonghui Fan, Pengfei Liao, Min Liu, Weike Yang, Xingxing Li, Zhanpeng Dong

    Published 2025-06-01
    “…Quantitative PCR (qPCR) validated the transcriptomic data, confirming the reliability of the results. …”
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  19. 2479

    A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML by Xue-Ping Li, Yan Gao, Bai-Tian Zhao, Yu-Ting Dai, Jia-Ying Mao, Yang Liang, Lu Jiang

    Published 2025-07-01
    “…We hypothesize that integrating single-cell transcriptomic and chromatin accessibility landscapes underlying t(8;21) AML will provide valuable insights into its heterogeneous cellular properties and gene regulatory programs. …”
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    Article
  20. 2480

    Nitrate nitrogen uptake and metabolism in Mikania micrantha stem: insights into enhanced growth and invasiveness by Minling Cai, Lihua Chen, Minghao Chen, Weiqian Ke, Dongguang Wang, Changlian Peng

    Published 2025-05-01
    “…This study investigates the unique adaptation strategies of M. micrantha to elevated NO3⁻-N levels, providing novel insights into its invasive success under changing nitrogen deposition patterns. …”
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    Article