-
2461
Lack of nAChR activity depresses cochlear maturation and up-regulates GABA system components: temporal profiling of gene expression in alpha9 null mice.
Published 2010-02-01“…Time-series analysis of whole transcriptome patterns, represented as self-organizing maps, revealed a disparate pattern of gene expression between alpha9(-/-) and wild type cochleae at the onset of hearing (P13), with knockout samples resembling immature postnatal ages.…”
Get full text
Article -
2462
COVID-19 related epigenetic changes and atopic dermatitis: An exploratory analysis
Published 2025-01-01“…Methods: We combined Mendelian randomization and transcriptome analysis for data-driven explorations. …”
Get full text
Article -
2463
Genome-wide identification of the phosphofructokinase gene family in maize (Zea mays L.) and their expression levels under abiotic stress and phytohormones
Published 2025-07-01“…We identified the ZmPFK genes involved in stress and plant hormone response by combining promoter element analysis, transcriptome data, and RT-qPCR analysis. This study provides valuable insights into the involvement of maize glycolysis in stress response.…”
Get full text
Article -
2464
Viral IL-10 can promote the proliferation, migration and invasion of nasopharyngeal carcinoma cells and inhibit their apoptosis
Published 2025-02-01“…The purpose of this study was to provide a theoretical basis for potential targets and mechanisms of vIL-10 in nasopharyngeal carcinoma. …”
Get full text
Article -
2465
Distinct effects of two dominant enteric bacteria on the developmental performance of Spodoptera frugiperda and their association with physiological metabolism
Published 2025-03-01“…For instance, the downregulation of UDP-glycosyltransferase (UGT) and amino acid genes is closely associated with the growth and development of Spodoptera frugiperda.These findings provide deeper insights into its impact on the growth and development of S. frugiperda.…”
Get full text
Article -
2466
Transcriptional analysis of Camellia Huana under low-phosphorus stress
Published 2025-05-01“…Abstract The molecular mechanism underlying the response of C. huana to low-phosphorus (P) stress was explored with transcriptome sequencing to analyze the genome-wide responses of plants exposed to different durations of low-P stress. …”
Get full text
Article -
2467
Cis-regulation analysis of RNA m6A methylation and gene expression in colorectal cancer
Published 2025-08-01“…Moreover, 34 genes showing strong correlations (r2 ≥ 0.9) were identified, including 16 genes previously reported to be associated with CRC. This study provides a transcriptome-wide strategy for quantifying the association between RNA methylation and gene expression in CRC, offering new insights into the potential regulatory roles of RNA methylation in tumor biology.…”
Get full text
Article -
2468
In silico screening of differentially expressed genes influenced by AFAP1-AS1 in lung adenocarcinoma
Published 2025-09-01“…Dysregulation of lncRNAs has an essential impact on the transcriptome, influencing cellular functions and behaviors. …”
Get full text
Article -
2469
Integrated analysis of physiological responses and transcriptional regulation in kiwifruit under high temperature
Published 2025-07-01“…Taken together, our results provide a dependable and useful information on the heat response in kiwifruit plants.…”
Get full text
Article -
2470
IrSPI, a tick serine protease inhibitor involved in tick feeding and Bartonella henselae infection.
Published 2014-07-01“…IrSPI silencing impaired tick feeding, as well as resulted in reduced bacterial load in tick SGs. This study provides a comprehensive analysis of I. ricinus SG transcriptome and contributes significant genomic information about this important disease vector. …”
Get full text
Article -
2471
Effects of silencing StSOBIR1-like gene on potato in response to herbivory
Published 2024-08-01“…After that, a bioassay of the potato tuber moth (Phthorimaea operculella) and the transcriptome sequencing were carried out with these plants to investigate the influence of silencing StSOBIR1-like gene on the potato defense response to the potato tuber moth. …”
Get full text
Article -
2472
Characterization of Dynamin-related proteins (DRP) in bread wheat: TaDRP1D-B as regulator of biotic and abiotic stresses
Published 2024-12-01“…Bread wheat (Triticum aestivum) is a vital global staple food, providing 30 % of the world's caloric intake and nutritional needs. …”
Get full text
Article -
2473
Antimicrobial dual-crosslinked hydrogel synergizes bioengineered extracellular vesicles for enhanced diabetic wound healing
Published 2025-06-01“…Antimicrobial hydrogel dressings combined with bioengineered EVs, will provide a good solution to the problem of difficult healing of diabetic wounds. …”
Get full text
Article -
2474
Gene co-expression network and differential expression analyses reveal key genes for weaning weight in Simmental-Holstein crossbred cattle
Published 2024-12-01“…In conclusion, this study reveals new candidate genes significantly associated with weaning weight in Simmental-Holstein crossbred cattle, providing a basis for further exploration of the genetic mechanisms behind growth traits of cattle.…”
Get full text
Article -
2475
The symbiont Wolbachia increases resistance to bifenthrin in Ectropis grisescens by regulating the host detoxification function
Published 2025-01-01“…These results suggest that Wolbachia may contribute to the resistance of E. grisescens to bifenthrin by regulating cytochrome P450 genes, providing a foundation for further study on the mechanism of symbiont-mediated host detoxification metabolism in insect pests.…”
Get full text
Article -
2476
The translatome of glioblastoma
Published 2025-03-01“…Our findings demonstrate that ribosome sequencing provides more detailed information than MS or transcriptional analyses. …”
Get full text
Article -
2477
Characterization, Expression Profile Analysis, and Functional Prediction of <i>UGP</i> Gene Family in <i>Dendrocalamus brandisii</i>
Published 2025-05-01“…This study suggests that the evolutionarily conserved <i>DbUGPs</i> exhibit mutual coordination and dynamic expression during <i>D. brandisii</i> growth, providing fresh insights into their functional roles.…”
Get full text
Article -
2478
Histopathological and Transcriptional Changes in Silkworm Larval Gonads in Response to Chlorfenapyr Exposure
Published 2025-06-01“…Quantitative PCR (qPCR) validated the transcriptomic data, confirming the reliability of the results. …”
Get full text
Article -
2479
A multi-omic single-cell landscape reveals transcription and epigenetic regulatory features of t(8;21) AML
Published 2025-07-01“…We hypothesize that integrating single-cell transcriptomic and chromatin accessibility landscapes underlying t(8;21) AML will provide valuable insights into its heterogeneous cellular properties and gene regulatory programs. …”
Get full text
Article -
2480
Nitrate nitrogen uptake and metabolism in Mikania micrantha stem: insights into enhanced growth and invasiveness
Published 2025-05-01“…This study investigates the unique adaptation strategies of M. micrantha to elevated NO3⁻-N levels, providing novel insights into its invasive success under changing nitrogen deposition patterns. …”
Get full text
Article