Preservation of milk in liquid nitrogen during sample collection does not affect the RNA quality for RNA-seq analysis by Lucía Jiménez-Montenegro, Leopoldo Alfonso, Beatriz Soret, José A. Mendizabal, Olaia Urrutia

“…Thus, this procedure, together with the subsequent RNA isolation from milk fat globules and its sequencing by RNA-seq, would provide a practical and a non-invasive method for measuring the mammary epithelial cell transcriptome, improving the feasibility of conducting studies related to mammary gland and lactation physiology.…”
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Some molecular aspects of larval development in Paralithodes camtschaticus. by Alexey V Boyko, Igor Yu Dolmatov, Alexander S Girich, Sergey I Maslennikov

“…The transcriptome of the red king crab, Paralithodes camtschaticus, was sequenced at four developmental stages: zoea I, zoea IV, glaucothoe, and juveniles. …”
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PARP inhibitors elicit a cellular senescence mediated inflammatory response in homologous recombination proficient cancer cells by Misato Kamii, Ryo Kamata, Hitoshi Saito, Gaku Yamamoto, Chiaki Mashima, Toyohiro Yamauchi, Takehiro Nakao, Yuta Sakae, Tomoko Yamamori-Morita, Kazuki Nakai, Yumi Hakozaki, Masataka Takenaka, Aikou Okamoto, Akihiro Ohashi

“…This study investigates senescence-mediated inflammation as a novel mechanism of action for PARP inhibitors in HRP cancers. Transcriptome analyses were performed in olaparib-treated HeLa cells as a HRP model. …”
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A Zeolitic Imidazolate Framework-Based Antimicrobial Peptide Delivery System with Enhanced Anticancer Activity and Low Systemic Toxicity by Jingwen Jiang, Kaderya Kaysar, Yanzhu Pan, Lijie Xia, Jinyao Li

“…We characterized this system in terms of morphology, particle size, zeta potential, infrared (IR), x-ray diffraction (XRD), and transcriptome analysis, and examined the in vitro cytotoxicity and cellular uptake properties of CEC@ZIF-8 using cervical cancer cells. …”
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Exploring ischemic stroke based on the ferroptosis perspective: ECH1 may serve as a new biomarker and therapeutic target by Rendong Qu, Yiyan Zhang, Haojia Zhang, Ke Li, Boning Zhang, Hongxuan Tong, Tao Lu

“…This study demonstrates that enoyl-coA hydrolase 1 (ECH1) may serve as a peripheral biomarker and therapeutic target for IS based on ferroptosis signaling.MethodsWe integrated transcriptome data from the GEO database with preprocessing and normalization. …”
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Insulin-Degrading Enzyme Regulates mRNA Processing and May Interact with the CCR4-NOT Complex by Barbara Bertocci, Ayse Yilmaz, Emmanuelle Waeckel-Énée, Chiara Guerrera, Kevin Roger, Lamine Touré, Peter M. van Endert

“…We used proteomics and transcriptomics approaches to search for leads related to a broader role of Ide in protein homeostasis. …”
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Genome-wide identification and expression analysis of ACS and ACO gene family in Ziziphus jujuba mill during fruit ripening by Zhuo Chen, Gang Jin, Zhaokun Zhi, Yanmeng Guo, Yiteng Liu, Bingxin Fan, Gao-Pu Zhu, Mengmeng Zhang, Shulin Zhang

“…This study sheds light on the genetic regulation of ethylene biosynthesis in ‘Dongzao’ jujube ripening, providing insights for postharvest research in this economically important species.…”
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Construction of a Multi-Omics database for Paeonia lactiflora: A resource for comprehensive data integration and analysis by Zongran Lu, Ling Huang, Somnuk Bunsupa, Hamizah Shahirah Hamezah, Xiaohui Tong, Chuanshan Jin, Jinmei Ou, Rongchun Han

“…With the advancement of omics technologies, significant genomic, transcriptomic, proteomic, and metabolomic data related to P. lactiflora have been generated. …”
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Multiomics Analysis Identifies Prognostic Signatures for Sepsis-Associated Hepatocellular Carcinoma in Emergency Medicine by Xin Chu, Qi Wu, Linglin Kong, Qiang Peng, Junhua Shen

“…We conducted analyses by obtaining gene transcriptome data and clinical data of HCC cases from The Cancer Genome Atlas (TCGA). …”
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Stem Cell-Associated Signatures Help to Predict Diagnosis and Prognosis in Ovarian Serous Cystadenocarcinoma by Li Li, Weiwei Zhang, Jinxin Qiu, Weiling Zhang, Mengmeng Lu, Jiaqian Wang, Yunfeng Jin, Qinghua Xi

“…The platinum resistance in OV is driven by transcriptome heterogeneity and tumor heterogeneity. …”
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Metabolic Engineering for the Biosynthesis of Pentalenene in the Rapidly Growing Bacterium <i>Vibrio natriegens</i> by Lujun Hu, Rui Lin, Hui Jiang, Ge Yao, Jiajia Liu, Penggang Han, Xiukun Wan, Chang Chen, Yunfei Zhang, Shaoheng Bao, Fuli Wang

“…This study confirmed the potential of <i>V. natriegens</i> as a pentalenene production platform and revealed its metabolic bottleneck, providing a theoretical basis for subsequent engineering optimization.…”
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The Exploration of <i>Cordyceps militaris</i> Extract as a Postharvest Preservative for <i>Flammulina filiformis</i> by Wenjing Chen, Yan Li, Youran Shao, Hongyu Chen, Ming Gong, Li Wang, Nanyi Li, Ying Wang, Gen Zou

“…The results demonstrated that CME could effectively extend the shelf life of <i>F. filiformis</i>, providing valuable insights into preservation strategies for this and other edible fungi.…”
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CDKN2D-WDFY2 is a cancer-specific fusion gene recurrent in high-grade serous ovarian carcinoma. by Kalpana Kannan, Cristian Coarfa, Kimal Rajapakshe, Shannon M Hawkins, Martin M Matzuk, Aleksandar Milosavljevic, Laising Yen

“…The genomic breakpoint was identified in intron 1 of CDKN2D and intron 2 of WDFY2 in patient tumor, providing direct evidence that this is a fusion gene. …”
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Proline Improves Pullulan Biosynthesis Under High Sugar Stress Condition by Keyi Liu, Junqing Wang, Feng Li, Ruiming Wang, Qingming Zeng, Zhenxing Zhang, Hongwei Liu, Piwu Li

“…<i>pullulans</i> against high sugar and hyperosmotic stress, providing a new theoretical basis and strategy for the efficient industrial production of pullulans.…”
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Comprehensive Analysis of the Transcriptional and Mutational Landscape of Follicular and Papillary Thyroid Cancers. by Seong-Keun Yoo, Seungbok Lee, Su-Jin Kim, Hyeon-Gun Jee, Byoung-Ae Kim, Hyesun Cho, Young Shin Song, Sun Wook Cho, Jae-Kyung Won, Jong-Yeon Shin, Do Joon Park, Jong-Il Kim, Kyu Eun Lee, Young Joo Park, Jeong-Sun Seo

“…The novel molecular subtype, NBNR, was associated with DICER1, EIF1AX, IDH1, PTEN, SOS1, SPOP, and PAX8-PPARG. The transcriptome of miFTC or encapsulated FVPTC was indistinguishable from that of FA, providing a molecular explanation for the similarly indolent behavior of these tumors. …”
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An Investigation of RNA Methylations with Biophysical Approaches in a Cervical Cancer Cell Model by Buket Sağlam, Onur Akkuş, Azime Akçaöz-Alasar, Çağatay Ceylan, Günnur Güler, Bünyamin Akgül

“…Although various methods exist that enable the analysis of RNA methylation in a site-specific or transcriptome-wide manner, whether biophysical approaches can be employed to such analyses is unexplored. …”
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AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortion by Yihong Chen, Bei Gan, Shan Zheng, Xiumei Zhao, Leiyi Jin, Juanbing Wei

“…Furthormore, Met and 2-DG promoted the differentiation of CD4+ T cells into Treg cells, providing theoretical basis for clinical prevention of URSA.…”
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Ursolic acid suppresses triple-negative breast cancer progression through mediating FABP4/PPARG pathway by Ying Deng, Junyi Wu, Di Pan, Wan Su, Songpo Wang

“…Methods TNBC cells were exposed to a graded concentration of UA, and cell proliferation and migration were examined through CCK-8 and wound healing assays. Transcriptome data of 116 TNBC and 290 normal tissues were acquired for determining differentially expressed genes. …”
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Application of multi-omics technology in pathogen identification and resistance gene screening of sheep pneumonia by Kai Huang, Lvfeng Yuan, Jia Liu, Xiaolong Li, Dan Xu, Xiaoxue Zhang, Jie Peng, Huibin Tian, Fadi Li, Weimin Wang

“…Results Here, we assessed the impact of pneumonia on sheep growth by evaluating the pneumonia phenotypes of 912 sheep. High-throughput transcriptome sequencing of 40 lungs was conducted to obtain exogenous RNA fragments for microbial sequence alignment. …”
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Cepharanthine hydrochloride: a novel ferroptosis-inducing agent for prostate cancer treatment by Jing-Song Guan, Jing Jia, Ze-Xiu Huang, Yu-Qing Zhou, Jing-Jie Zheng, Qi-Man Lin, Yi-Fei Wang, Jiang-Lin Fan, Yao Wang, Yao Wang

“…The multiple mechanisms we found provides strong evidence for the eventual clinical application of the drug.…”
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