Shared gene signatures and molecular mechanisms link ankylosing spondylitis and rheumatoid arthritis by Boli Qin, Xiaopeng Qin, Jie Ma, Chenxing Zhou, Tianyou Chen, Jichong Zhu, Chengqian Huang, Shaofeng Wu, Rongqing He, Songze Wu, Sitan Feng, Jiarui Chen, Jiang Xue, Wendi Wei, Tengxiang Long, Quan Pan, Kechang He, Zhendong Qin, Tiejun Zhou, Jiayan Jiang, Xinli Zhan, Chong Liu

“…Our integrative approach combining machine learning, transcriptomics, and clinical validation, provides novel insights into shared mechanisms, positioning MYO1F and neutrophils as potential diagnostic and therapeutic targets.…”
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Salt Stress Leads to Morphological and Transcriptional Changes in Roots of Pumpkins (<i>Cucurbita</i> spp.) by Hongjiu Liu, Ding Ding, Yeshuo Sun, Ruiping Ma, Xiaoqing Yang, Jie Liu, Guoxin Zhang

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Characterizing age-related features for assessing biological age and characteristics in Xinjiang Brown cattle by Jiahao Wang, Menghua Zhang, Qingyao Zhao, Siqian Chen, Yongjie Tang, Quanzhen Chen, Lei Xu, Dan Wang, Xiaoping Guo, Kai Xing, Yachun Wang, ChuduanWang, Xixia Huang, Ying Yu

“…Linear genes were selected using elastic network regression to construct a transcriptomic clock and estimate the biological age of each sample. …”
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Pseudovibriamides from Pseudovibrio marine sponge bacteria promote flagellar motility via transcriptional modulation by Yitao Dai, Vitor Lourenzon, Laura P. Ióca, Dua Al-Smadi, Lydia Arnold, Ian McIntire, Roberto G. S. Berlinck, Alessandra S. Eustáquio

“…Thus, this work gives insights into pseudovibriamide biosynthesis and provides evidence that they are signaling molecules relevant to bacterial motility and to other yet-to-be-identified phenotypes.…”
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Deep phenotyping of patients with MASLD upon high-intensity interval training by Veera Houttu, Ulrika Boulund, Marian Troelstra, Susanne Csader, Daniela Stols-Gonçalves, Anne Linde Mak, Anne-Marieke van Dijk, Julia Bouts, Maaike Winkelmeijer, Xanthe Verdoes, Sandra van den Berg-Faay, Donne Lek, Ted Ronteltap, Ferdinand de Haan, Harald Jorstad, Ville Männistö, Kai Savonen, Heikki Pentikäinen, Kati Hanhineva, Ambrin Farizah Babu, Gianni Panagiotou, Otto van Delden, Joanne Verheij, Michial Doukas, Aart Nederveen, Ursula Schwab, Aldo Grefhorst, Max Nieuwdorp, Adriaan Georgius Holleboom

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Continuous cell lines derived from the Asian citrus psyllid, Diaphorina citri, harbor viruses and Wolbachia by Ke Wu, Emily D. Vu, Saptarshi Ghosh, Ruchir Mishra, Bryony C. Bonning

“…Cell lines derived from D. citri can provide insight into both the basic biology of this pest and D. citri-associated pathogens including CLas. …”
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Genome-wide identification and analysis of the HD-Zip transcription factor family in oats by Yiqun Xu, Yiqun Xu, Changlai Liu

“…Under drought and salt stress, the expression levels of a large number of oat HD-Zip genes were significantly induced or suppressed, indicating that these HD-Zip genes are likely to be involved in regulating the oat’s response to adversity.ConclusionsThe results of this study provide excellent candidate HD-Zip genes for the study of oat resistance, and provide a reference for oat gene improvement and genetic breeding.…”
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Mitochondrial-derived gene expression in hibernation: tissue-specific responses in the thirteen-lined ground squirrel by Sarah Viola Emser, Eva Millesi

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Transcriptional landscape of pleural mesothelioma patients in relation to NF2 gene mutational status by Carlos Orozco-Castaño, Alejandro Mejía-Garcia, Hsuan Megan Tsao, Diego A. Bonilla, Carlos Carvajal-Fierro, Ricardo Bruges-Maya, Alba Combita, Rafael Parra-Medina

“…Single-cell RNA sequencing data provided further insights into transcriptional patterns in NF2-mutated tumors. …”
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New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels by Huan Zhao, Huan Zhao, Xu Dong, Xu Dong, Dazuo Yang, Dazuo Yang, Qingchao Ge, Qingchao Ge, Peng Lu, Peng Lu, Chang Liu, Chang Liu

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The transcription factor PoMbp1 promotes the growth and development of Pleurotus ostreatus by regulating polysaccharide utilisation by Lijiao Zhang, Yingjie Zhang, Zeyin Wu, Mengran Zhao, Xiangli Wu, Chenyang Huang

“…These results indicated that PoMbp1 plays a positive role in fruit body development by enhancing the expression of genes related to polysaccharide utilisation. This study provides a theoretical reference for research on the mechanism of fruiting body development of P. ostreatus.…”
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NAALAD2 mutations disrupt the fate of photoreceptor cells and retinal pigment epithelial cells during early retinal development by Yuanjie Qian, Jian Gao, Zheming Zhang, Yixuan Chen, Jindi Su, Xing Niu, Kaifeng Zheng, Yantao Bao, Yueyuan Qin, Junge Zheng, Yuankai Yang, Qunyan Wu, Ke Mo, Yantao Wei, Shan Duan

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Deciphering the role of SMU.1147 in peptide-mediated signaling and competence in Streptococcus mutans by Jeong Nam Kim, Si-Uk Ryoo, Yeuna Nam

“…In this study, we performed transcriptome analysis to investigate the role of SMU.1147, a unique core gene in S. mutans, in biological pathways related to transport, defense responses, and environmental sensing. …”
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Overexpression of Lol-miR11467 negatively affects osmotic resistance in Larix kaempferi 3 × L. gmelinii 9 by Sufang Zhang, Shanshan Yan, Li Zhang, Pingyu Yan, Hanguo Zhang, Lei Zhang

“…This study’s findings might provide a foundation for understanding the molecular mechanisms of miRNAs under PEG osmotic stress in larch, potentially contributing to the development of strategies for improving plant resilience to environmental stresses.…”
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ZmZFP2 encoding a C4HC3-type RING zinc finger protein regulates kernel size and weight in maize by Long Zhang, Qilei Wang, Wenyu Li, Qi Zheng, Miaomiao Fu, Han Wang, Xinyu Li, Yan Wang, Lingwei Hu, Weigang Yao, Lifeng Wang, Huiyong Li, Yongbin Dong, Yongrui Wu, Yuling Li

“…CRISPR/Cas9-mediated knockouts and overexpression lines confirmed that ZmZFP2 positively regulates kernel size and weight, with overexpression leading to increased kernel size and weight. Transcriptome analysis revealed that ZmZFP2 regulates genes involved in zeatin biosynthesis, starch metabolism, and protein processing, further supporting its role in kernel development. …”
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Overexpression of tRNA m7G modification methyltransferase complex promotes the biosynthesis of triterpene in yeast by Mengyu Ma, Jun Wang, Zhengwei Tan, Zhengwei Tan, Xiqin Liang, Bengui Fan, Lei Li, Lei Li, Huizhen Liang, Huizhen Liang, Tianyue An, Guoli Wang

“…Recent studies suggest that RNA modifications can influence cellular metabolism, but their role in metabolic engineering remains largely unexplored.MethodsThe production of squalene and lupeol in different yeast strains was detected by gas chromatography-mass spectrometry (GC-MS) equipment. Transcriptomic analysis was performed to identify metabolic changes associated with the epigenetic modification. …”
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Downregulation of PGK1 promotes lipid peroxidation and suppresses proliferation in cervical cancer revealed by liquid-liquid phase separation-related gene signature by Beilei Zhang, Zhanghang Li, Zhaojie Yang, Yidan Yin, Mingke Duan, Lei Wang, Qirui Zhan, Fu Wang, Ruifang An

“…This study leverages single-cell sequencing and transcriptome analysis to identify LLPS-linked therapeutic targets in cervical cancer. …”
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Investigating the Mechanisms Underlying Citral-Induced Oxidative Stress and Its Contribution to Antifungal Efficacy on <i>Magnaporthe oryzae</i> Through a Multi-Omics Approach by Yonghui Huang, Ruoruo Wang, Yumei Tan, Yongxiang Liu, Xiyi Ren, Congtao Guo, Rongyu Li, Ming Li

“…In this study, we investigated the oxidative effects of citral on <i>M. oryzae</i> and conducted transcriptomic and widely targeted metabolomic (WTM) analyses on the mycelia. …”
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The impact of carbon-ion beam irradiation on the phenotypic and molecular variation of wheat by Huihui Fan, Qianwen Xue, Hongchun Xiong, Huijun Guo, Yongdun Xie, Linshu Zhao, Jiayu Gu, Shirong Zhao, Yuping Ding, Huiyuan Li, Libin Zhou, Luxiang Liu

“…Conclusion This study provides valuable information and resources for mutation breeding in crops, enhancing our understanding of carbon-ion-beam-induced mutations in wheat.…”
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Study on Antifungal Mechanism of Lipopeptide Extract from Bacillus amyloliquefaciens Against Alternaria alternata in Tomato by Yingying FAN, Yingying DAI, Yuanyuan ZHANG, Tingting SHEN, Yan WANG, Peicheng WANG, Fengjuan LIU, Cheng WANG

“…【Objective】This study elucidated the antifungal rate and mechanism of lipopeptide extracts from Bacillus amyloliquefaciens against Alternaria alternata in tomatoes, aiming to provide scientific basis for green control of black spot disease in tomatoes.…”
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