Multi‐Omics Analysis Reveals the Selenium‐Regulatory Metabolism in Rare Yeast Kazachstania unispora KU2 by Furong Wang, Jiadi Zhang, Yilei Xiao, Zeyu Hu, Xian Wang, Yuqi Gao, Kewei Feng, Yahong Yuan, Tianli Yue

“…This study explored the characteristic differences between Se‐enriched K. unispora KU2 and non‐enriched counterpart via integrated genomics, transcriptomics, and metabolomics analysis. A total of 138 metabolites and 1561 genes exhibited significant alternations during Se enrichment. …”
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Multi-omics joint analysis reveals the mechanism of flower color and fragrance variation in Lilium cernuum by Shaopeng Chen, Zhiqun Chen, Qianqian Zhuang, Hewen Chen

“…The UFGT-mediated glycosylation defect provides a novel explanation for anthocyanin instability in white petals. …”
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Navarixin alleviates cardiac remodeling after myocardial infarction by decreasing neutrophil infiltration and the inflammatory response by Peikun Hu, Wei Liu, Jungang Huang, Yangfan Su, Huiqi Jiang, Qinyu Wu, Jun Tao, Shi Liang, Jun Lin, Junmeng Zheng

“…This study provides new insights for the use of CXCR2 inhibitors as new therapeutic options for myocardial infarction in the future.…”
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Identification and Preliminary Functional Analysis of Responsive Genes to Short-term Heat Stress in Lettuce by Shuping He, Guotao Huo, Guojun Ge, Li Du, Du Long, Lijun Luo, Ping Long, Shiwei Wei

“…These findings provide a basis to comprehensively understand the complex molecular mechanism of lettuce response to heat stress.…”
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Omics based technology application in poultry meat research by Huaijun Zhou, Austin Quach, Mahesh Nair, Behnam Abasht, Byungwhi Kong, Brian Bowker

“…Omics techniques, including genomics, transcriptomics, proteomics, metabolomics, and lipidomics, analyze entire sets of biological molecules to seek comprehensive knowledge on a particular phenotype. …”
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Age-specific effects of synthetic cannabinoids on cognitive function and hippocampal gene expression in mice: insights from behavioral and molecular correlates by Kaixi Li, Kaixi Li, Yuanyuan Chen, Yuanyuan Chen, Yawen Xu, Yawen Xu, Yuan Pang, Yongli Bao, Simeng Zhang, Simeng Zhang, Xuesong Shi, Xuesong Shi, Jingzhi Ran, Jingzhi Ran, Yanling Qiao, Yanling Qiao, Yanling Qiao, Yizhao Xu, Yizhao Xu, Yiming Wang, Bin Di, Bin Di, Peng Xu, Peng Xu

“…Here, we first investigated the effects of a single exposure of the fourth-generation synthetic cannabinoid 4F-ABUTINACA on cognitive behaviors in adolescent (PND 28–35 days) and adult (PND 49–56 days) male mice in an animal model, followed by an age-specific systematic study by conducting a whole-gene transcriptomics study of hippocampal tissue in the brain. …”
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Lethal neonatal acidosis: Multiomic investigation of a novel HIBCH variant as the underlying cause by Sonali Patel, Muhammad Zain-ul-abideen, Genevieve Guyol, Lance H. Rodan, Casie A. Genetti, Amy Z. Ren, Philip Connors, Patricia Davenport, Ruby Bartolome, Inderneel Sahai, Vijay S. Ganesh, Monica H. Wojcik

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Vitamin and zeatin treatments promote colchicine-induced haploid chromosome doubling in maize by Chen Chen, Yuling Zhang, Chenxu Liu, Jinlong Li, Jiuran Zhao, Yuandong Wang, Shaojiang Chen

“…In a parallel experiment, exogenous vitamins including thiamine, nicotinic acid, vitamin B6, or trans-zeatin were added to colchicine treatment; there were synergistic effects between vitamins or zeatin and colchicine in haploid artificial chromosome doubling. These results provide novel insights in exploring the molecular responses to antimitotic reagents at both the transcriptomic and metabolomic levels. …”
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Study on gene expression in stomach at different developmental stages of human embryos by Weiyu Guan, Xinran Lu, Yin Zhang, Hongping Ding, Xinmei Liu, Le Yang, Wenran Wang, Jianwu Shi, Shichun Feng

“…As gastric development, the stomach progressively acquires additional functions. This research provides insights into the intricate regulatory networks among the genes involved in embryonic digestive tract development, digestion and embryonic organ morphogenesis. …”
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The Virulence Factor LLO of <i>Listeria monocytogenes</i> Can Hamper Biofilm Formation and Indirectly Suppress Phage-Lytic Effect by Banhong Liu, Mei Bai, Wuxiang Tu, Yanbin Shen, Jingxin Liu, Zhenquan Yang, Hongduo Bao, Qingli Dong, Yangtai Liu, Ran Wang, Hui Zhang, Liangbing Hu

“…These observations highlight the important role of virulence factors in phage applications and provide insights into the potential use of phages for developing biosanitizers.…”
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Moderate Septoria apocyni infection enhances flavonoid and mineral elements accumulation in Apocynum venetum leaves by Panpan Shang, Yanglu Ran, Xinchun Ge, Li Wang, Meiting Bai, Jiming Yang, Yonghe Cai, Tingyu Duan

“…This study employed transcriptomics technology to elucidate the molecular mechanisms underlying the response of A. venetum to spot blight, while simultaneously investigating flavonoid and mineral elements content of the leaves. …”
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Salt gradient-driven adaptation in okra: uncovering mechanisms of tolerance and growth regulation by Xi Yang, Jiuxing He, Jiuxing He, Lifeng Xu, Meng Kong, Qiuyan Huo, Jiqing Song, Wei Han, Guohua Lv, Guohua Lv

“…Here, we integrated physiological phenotyping with transcriptome profiling to elucidate the stage-specific strategies employed by okra in response to NaCl stress. …”
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Distinct Molecular Profiles Underpin Mild-To-Moderate Equine Asthma Cytological Profiles by Anna E. Karagianni, Eric A. Richard, Marie-Pierre Toquet, Erika S. Hue, Anne Courouce-Malblanc, Bruce McGorum, Dominic Kurian, Judit Aguilar, Stella Mazeri, Thomas M. Wishart, Robert Scott Pirie

“…Our adopted multi-omics approach provided a holistic assessment of the immunological status of the lower airways associated with the different cytological profiles of equine asthma.…”
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Multi-omics investigation of high-transglutaminase production mechanisms in Streptomyces mobaraensis and co-culture-enhanced fermentation strategies by Huanan Chang, Ziyu Zheng, Hao Li, Yanqiu Xu, Gengyao Zhen, Yao Zhang, Xidong Ren, Xidong Ren, Xinli Liu, Xinli Liu, Deqiang Zhu, Deqiang Zhu

“…Using this strain as a forward mutation gene pool, comparative genomic research identified 95 mutated genes, which were mostly due to base substitutions that led to changes in codon usage preference. Transcriptomic analysis revealed significant expression changes in 470 genes, with 232 upregulated and 238 downregulated genes. …”
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Production, characterization, and potential utility of a newly synthesized allohexaploid wheat Triticum kiharae by Tariq Aslam, Tianying Zhang, Taotao Lian, Jiawen Zhai, Jinning Jia, Han Wang, Ruili Lyu, Bao Liu

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Physiological resistance of Dendrocalamus brandisii culms to alcohol stress during living bamboo wine production process by Yingdan Yan, Yufang Wu, Chongsheng Zhao, Fangwei Zhu, Jiaxin Liu, Sushuang Wang, Shuguang Wang

“…Methods To investigate the resistance of bamboo culms to the alcohol-induced stress, we conducted a comprehensive analysis of various factors, including changes in cell wall chemical components, antioxidant defense systems, endogenous plant hormones and transcriptomics, both before and after the alcohol injection. …”
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Dissection of genetic basis underlying heat stress response of Apis cerana by Ao-Mei Li, Chun-Xiu Pang, Xiao-Lin Cai, Fu-Chang Zhuo, Bo Hu, Xue-Hua Huang, Jia-Xing Huang, Yu-Ming Lu

“…Here, we conducted transcriptomic analysis to identify differentially expressed genes (DEGs) and reveal the associated biological processes in the queen head and ovary of honeybee A. cerana under different temperatures. …”
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Altered aminoacid and lipid metabolism in a rat orofacial inflammation model determined by omics approach: potential role in trigeminal sensitisation by Krisztina Takács-Lovász, Timea Aczél, Violetta Mohos, Máté Harmath, Jennet Pirkuliyeva, Gellért Karvaly, Róbert Farkas, Michal Ciborowski, Joanna Godzien, Kata Bölcskei, József Kun, Zsuzsanna Helyes

“…Conclusions Integrated joint pathway analysis of metabolomic and transcriptomic data provides a useful approach to determine pathophysiological mechanisms of trigeminal sensitization and identify novel drug targets for orofacial pain and headaches.…”
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Molecular Elucidation of Anthocyanin Accumulation Mechanisms in <i>Hippeastrum hybridum</i> Cultivars by Pengyu Guo, Chuanji Xing, Jiacheng Ye, Jing Xue, Luis A. J. Mur, Bao Di, Zongli Hu, Guoping Chen, Xiuhai Zhang, Xuqing Chen

“…Weighted gene co-expression network analysis (WGCNA) correlated the abundance of these four anthocyanins with transcriptomic data, to suggest three regulatory modules. …”
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Single-cell RNA sequencing highlights the influence of innate and adaptive immune response mechanisms in psoriatic arthritis by Melanie R. Nielsen, Marie Skougaard, Marie Skougaard, Marie Skougaard, Clara Drachmann, Zara R. Stisen, Sisse B. Ditlev, Leon E. Jessen, Lars Erik Kristensen, Lars Erik Kristensen

“…No DEGs were discovered in the direct comparison of PsA-only and PsA/PsC patients.DiscussionThe single-cell transcriptome profiling provided insight into the heterogeneity of PsA patients as the discovered DEGs and the GSEA did demonstrate differences in signaling associated with inflammation comparing PsA patients with and without cutaneous psoriasis.…”
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