Response mechanism of ethanol-tolerant Saccharomyces cerevisiae strain ES-42 to increased ethanol during continuous ethanol fermentation by Xue-Xue Ji, Quan Zhang, Bai-Xue Yang, Qing-Ran Song, Zhao-Yong Sun, Cai-Yun Xie, Yue-Qin Tang

“…The findings suggest that the longevity-regulating pathway may play a critical role in adapting to varying ethanol stress by regulating mitochondrial respiration, glycerol synthesis, ergosterol synthesis, antioxidant enzyme, and HSPs. This work provides a novel and valuable understanding of the mechanisms that govern ethanol tolerance during continuous fermentation.…”
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Effects of Different Stocking Densities on Snail <i>Bellamya purificata</i> Foot Muscle Nutritional Quality and Metabolic Function by Yingyue Lou, Rui Jia, Bing Li, Linjun Zhou, Jian Zhu, Yiran Hou

“…These findings elucidated the response mechanisms of <i>B. purificata</i> to adverse stocking density conditions and provide data and a theoretical basis for selecting appropriate stocking densities for <i>B. purificata</i>.…”
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Genome-wide identification of the AcBAM family in kiwifruit (Actinidia chinensis cv. Hongyang) and the expression profiling analysis of AcBAMs reveal their role in starch metabolis... by Xuchen Gong, Mengfei Lin, Jie Song, Jipeng Mao, Dongliang Yao, Zhu Gao, Xiaoling Wang

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Identification and analysis of drought-responsive F-box genes in upland rice and involvement of OsFBX148 in ABA response and ROS accumulation by Yifan Wang, Fang Chen, Yuyang Chen, Kaiwen Ren, Dan Zhao, Kun Li, Haipeng Li, Xiaobin Wan, Mu Peng, Zhixin Xiang, Qiaoyu Tang, Zhi Hou, Qing Fang, Yifeng Zhou, Yanke Lu

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Integrative and comparative analysis of whole-transcriptome sequencing in circCOL1A1-knockdown and circCOL1A1-overexpressing goat hair follicle stem cells by Jian Wang, Xi Wu, Liuming Zhang, Xiaomei Sun, Wei Sun, Kunzhe Dong, Yongjun Li

“…Conclusion These novel findings provide a valuable and comprehensive basis for investigating the complex mechanism by which circRNAs participate in and regulate HF development and SQBH formation in YRDWG.…”
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Characterization of the regulatory network and pathways in duodenum affecting chicken abdominal fat deposition by Zhijie Liu, Sibei Cheng, Xing Zhang, Miaomiao Yang, Jixiang Wei, Fei Ye, Zheng Ma, Huimin Kang, Zhengfen Zhang, Hua Li, Hai Xiang

“…The findings of this study provide a theoretical foundation for the molecular mechanisms of mRNAs and non-coding RNAs in duodenal tissues on abdominal fat deposition in chickens.…”
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Over Time Changes in the Transcriptomic Profiles of Tomato Plants with or Without <i>Mi-1</i> Gene During Their Incompatible or Compatible Interactions with the Whitefly <i>Bemisia... by Susana Pascual, Clara I. Rodríguez-Álvarez, Irene López-Vidriero, José M. Franco-Zorrilla, Gloria Nombela

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A three-way transcriptomic crosstalk interaction in a biocontrol agent (Bacillus velezensis), a fungal pathogen (Colletotrichum gloeosporioides), and a walnut host (Juglans regia L... by Shiwei Wang, Hanmingyue Zhu, Shuying Li, Tianhui Zhu

“…This study addresses knowledge gaps in the biocontrol-pathogen-host interaction and provides a theoretical foundation for developing environmentally sustainable strategies to control walnut anthracnose.…”
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Single-cell transcriptomic profiling reveals a novel signature of necrotizing granulomatous lesions in the lungs of Mycobacterium tuberculosis-infected C3HeB/FeJ mice by Shintaro Seto, Shiho Omori, Hajime Nakamura, Hajime Nakamura, Minako Hijikata, Naoto Keicho, Naoto Keicho

“…In conclusion, our results provide the immune landscape of necrotizing granulomas and reveal novel functional states of macrophages contributing to TB pathogenesis.…”
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Positive correlation between transcriptomic stemness and PI3K/AKT/mTOR signaling scores in breast cancer, and a counterintuitive relationship with PIK3CA genotype. by Ralitsa R Madsen, Emily C Erickson, Oscar M Rueda, Xavier Robin, Carlos Caldas, Alex Toker, Robert K Semple, Bart Vanhaesebroeck

“…Collectively, our analysis (1) provides evidence for a signaling strength-dependent PI3K-stemness relationship in human breast cancer; (2) supports evaluation of the potential benefit of patient stratification based on a combination of conventional PI3K pathway genetic information with transcriptomic indices of PI3K signaling activation.…”
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Integrated multi-omics analysis identifies TLR4-mediated mechanisms in ATBC-induced ovarian dysfunction and female infertility: A network toxicology, transcriptomic, and Mendelian... by Jinfa Huang, Lingling Zeng, Qian Yang, Kaixian Deng

“…Pathway analysis revealed significant enrichment in apoptosis, oxidative stress response, and PI3 K-AKT signaling (p < 0.05). Transcriptomic validation showed differential expression of 7/10 infertility-related and 9/10 ovarian damage-related hub genes. …”
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Effects of Rumen-Protected Methionine on Meat Quality, Fatty Acid Composition, Volatile Flavor Compounds and Transcriptomics of <i>Longissimus lumborum</i> of Yak (<i>Bos grunniens... by Xia Wu, Zizhen Zuo, Jiajia Li, Jianhui Fu, Jincheng Zhong, Hui Wang, Haitao Shi, Yanling Huang, Haibo Wang

“…In summary, the addition of RPM to diets may provide new ideas and methods to improve meat quality of yaks.…”
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Intake of Pyriproxyfen Through Contaminated Food by the Predator <i>Ceraeochrysa claveri</i> Navás, 1911 (Neuroptera: Chrysopidae): Evaluation of Long-Term Effects on Testes via Tr... by Jefferson Fogaça Tomacheski, Ana Silvia Gimenes Garcia, Rafael Takahiro Nakajima, Fábio Malta de Sá Patroni, Elton Luiz Scudeler, Rafael Henrique Nóbrega, Daniela Carvalho dos Santos

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Clinical assessment and transcriptome analysis of host immune responses in a vaccination-challenge study using a glycoprotein G deletion mutant vaccine strain of infectious laryngo... by Gayathri Gopakumar, Mauricio J. C. Coppo, Mauricio J. C. Coppo, Andrés Diaz-Méndez, Carol A. Hartley, Joanne M. Devlin

“…Significant differences were observed in the tracheal transcriptome of the non-vaccinated-challenged birds compared to the other two groups. …”
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Transcriptomic Analysis Reveals the Molecular Defense Mechanisms of <i>Poa pratensis</i> Against Powdery Mildew Fungus <i>Blumeria graminis</i> f. sp. <i>Poae</i> by Zhiyu Xu, Zhanchao Guo, Fan Wu, Yining Zhang, Yumin Zhao, Lingjuan Han, Peng Gao, Huisen Zhu, Qingfang Xu, Xiang Zhao, Yinping Liang

“…This study identified critical genes involved in powdery mildew resistance in <i>P. pratensis</i>, providing a basis for future gene mining and molecular breeding to increase disease resistance in <i>P. pratensis</i>.…”
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Current Technologies in Snake Venom Analysis and Applications by Henrique Roman-Ramos, Paulo Lee Ho

“…The application of synthetic biology and multi-omics approaches, collectively known as venomics, has revolutionized the field, providing deeper insights into venom function and its therapeutic potential. …”
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Breed-Associated Differences in Differential Gene Expression Following Immunotherapy-Based Treatment of Canine High-Grade Glioma by Susan A. Arnold, Walter C. Low, Grace Elizabeth Pluhar

“…Overall, this study confirmed that French bulldog HGG transcriptomes differ from boxer and Boston terrier transcriptomes, further refining description of the canine glioma transcriptome and providing important information to guide novel therapy development, both for specific dog breeds and for possible correlative variants of human glioblastoma.…”
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Integration of scRNA-seq and ST-seq identifies hyperproliferative RRM2+ cells features and therapeutic targets in gastric cancer by Shuai Ping, Xiong Jia, Yanan Tian

“…High-resolution single-cell RNA sequencing (scRNA-seq) integrated with spatial transcriptomics sequencing (ST-seq) elucidating the role of the CHC microenvironment in driving GC progression remains lacking. …”
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The Mining of Candidate Genes Involved in the Camphor Biosynthesis Pathway of <i>Cinnamomum camphora</i> by Yan Yang, Shengcai Zhou, Mingyang Ni, Yuting Zhang, Shixiong Lin, Junhong Zhang, Zaikang Tong

“…Twenty-one candidate genes involved in the camphor biosynthesis pathway were identified, providing a foundation for further elucidating the genetic mechanisms underlying camphor production in <i>C. camphora.…”
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Multi-omic serum analysis reveals ferroptosis pathways and diagnostic molecular signatures associated with Moyamoya diseases by Qingbao Guo, Manli Xie, Xiaopeng Wang, Cong Han, Gan Gao, Qian-Nan Wang, Jingjie Li, Lian Duan, Xiangyang Bao

“…We use multiple computational strategies to interpret complex information in serum, providing a comprehensive perspective for early diagnosis of MMD. …”
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