Integrated physiological and transcriptomic data revealed the cold-resistant mechanisms in reproductive organs of the ‘Jinguang’ pear cultivar by Mengying Sun, Mengying Sun, Shun Lin, Shun Lin, Zezhao Zhao, Weizhen Guo, Min Jiang, Min Jiang, Ying Li, Jun Zhang, Jun Zhang, Jingxian Zhao, Minsheng Yang, Minsheng Yang

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Emerging PPARγ-Independent Role of PPARγ Ligands in Lung Diseases by Ajit A. Kulkarni, Collynn F. Woeller, Thomas H. Thatcher, Sesquile Ramon, Richard P. Phipps, Patricia J. Sime

“…Some of these effects occur when PPARγ is pharmaceutically antagonized or genetically PPARγ and are thus independent of classical PPARγ-dependent transcriptional control. …”
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Constructing the biomolecular networks associated with diabetic nephropathy and dissecting the effects of biomolecule variation underlying pathogenesis by Zi-Han Wang, Qi Dong, Qian Yan, Wan-Rong Yu, Dan-Dan Zhang, Ran Yi

“…To address this, understanding the genetic regulation underlying DN is crucial for personalized treatment strategies. …”
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Functional characterization in Chimonobambusa utilis reveals the role of bHLH gene family in bamboo sheath color variation by Long Tong, Long Tong, Long Tong, Qingping Zeng, Yuan Guo, Yanjie Li, Hongyan Li, Lijie Chen, Xia Liu

“…IntroductionThe basic helix-loop-helix (bHLH) proteins are a large family of transcription factors that are essential to physiology, metabolism, and development. …”
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Translational regulation of PKD1 by evolutionarily conserved upstream open reading frames by Lei Chen, Xia Gao, Xiangshen Liu, Ye Zhu, Dong Wang

“…Mutations in PKD1 coding sequence and abnormal PKD1 expression levels contribute to the development of autosomal-dominant polycystic kidney disease, the most common genetic disorder. Regulation of PKD1 expression by factors located in the promoter and 3´ UTR have been extensively studied. …”
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Genomic characterization of noroviruses from an outbreak associated with oysters by Annika Flint, Jennifer Harlow, Madison McLeod, Madeleine Blondin-Brosseau, Kelly Weedmark, Neda Nasheri

“…In 2022, a multi-jurisdictional norovirus outbreak associated with contaminated oysters occurred that involved hundreds of illnesses. Here, we conducted genetic analysis on 30 clinical samples associated with this oyster outbreak. …”
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Transcriptomic data reveals MYC as an upstream regulator in laying hen follicular recruitment by Ashley E Kramer, Kathryn M Ellwood, Nicole Guarino, Cong-Jun Li, Aditya Dutta

“…This study investigates the genetic drivers mediating the transition of pre-recruitment follicles to the pre-ovulatory phase, a crucial stage before ovulation. …”
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Comparative Transcriptome Analysis Reveals Molecular Defensive Mechanism of Arachis hypogaea in Response to Salt Stress by Hao Zhang, Xiaobo Zhao, Quanxi Sun, Caixia Yan, Juan Wang, Cuiling Yuan, Chunjuan Li, Shihua Shan, Fengzhen Liu

“…Of these DEGs, 141 transcription factors (TFs) mainly consisting of MYB, AP2/ERF, WRKY, bHLH, and HSF were identified in response to salinity stress. …”
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Longitudinal association between DNA methylation and type 2 diabetes: findings from the KORA F4/FF4 study by Liye Lai, Dave Laurence Juntilla, Monica Del, Monica Del C Gomez-Alonso, Harald Grallert, Barbara Thorand, Aiman Farzeen, Wolfgang Rathmann, Juliane Winkelmann, Holger Prokisch, Christian Gieger, Christian Herder, Annette Peters, Melanie Waldenberger

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Genome-wide identification, characterization, and functional analysis of the CHX, SOS, and RLK genes in Solanum lycopersicum under salt stress by Amaal Maghraby, Mohamed Alzalaty

“…Quantitative reverse transcription PCR (qRT-PCR) results indicated that the expression levels of CHX, SOS, and RLK genes were upregulated, with fold changes of 1.83, 1.49, and 1.55, respectively, after 12 h of exposure to salt stress. …”
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Peroxisome Proliferator-Activated Receptor γ Regulates Lipid Metabolism in Sheep Trophoblast Cells through mTOR Pathway-Mediated Autophagy by Kexing Hao, Jing Wang, Hengbin Yu, Lei Chen, Weibin Zeng, Zhengrong Wang, Guangdong Hu

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Chronic Myeloid Leukemia Relapsing 25 Years after Allogenic Stem Cell Transplantation by Håkon Reikvam, Jørn Skavland, Stein-Erik Gullaksen, Randi Hovland, Tobias Gedde-Dahl, Øystein Bruserud, Bjørn Tore Gjertsen

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Development of real-time RT-PCR for N2 subtype avian influenza RNA-virus detection by P. B. Akshalova, A. V. Andriyasov, L. O. Scherbakova, S. N. Kolosov, N. G. Zinyakov, I. A. Chvala, D. B. Andreychuk

“…Various combinations of primers were tested against ten N2 avian influenza virus isolates that genetically differed from each other in N gene. Nine viruses were isolated from birds in the Russian Federation regions and classified to different genetic groups. …”
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A novel TGFBR2 mutation causes Loeys-Dietz syndrome in a Chinese infant: A case report by Xin Liu, Kaiqing Liu, Lifu Hu, Zixiao Liu, Xinhua Liu, Jiantao Wang

“…The p.Glu335_Tyr336delinsAsp mutation significantly reduced TGF-β-induced gene transcription and phosphorylation of SMAD Family Member 2 (SMAD2) in vitro. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…Deletion of the response regulator EutV eliminated this induction of eut mRNAs and BMCs, thus demonstrating that BMC formation is transcriptionally regulated by the TCS EutV-EutW in response to ethanolamine. …”
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DELLA MUTATIONS IN PLANTS WITH SPECIAL EMPHASIS ON WHEAT by G. A. Chebotar, S. V. Chebotar, Yu. M. Sivolap

“…DELLA proteins are a subfamily of transcriptional regulators from the GRAS protein family. …”
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STAT3 Genotypic Variant rs744166 and Increased Tyrosine Phosphorylation of STAT3 in IL-23 Responsive Innate Lymphoid Cells during Pathogenesis of Crohn’s Disease by Ying Tang, Sanda A. Tan, Atif Iqbal, Jian Li, Sarah C. Glover

“…Crohn’s disease (CD) results from dysregulated immune responses to gut microbiota in genetically susceptible individuals, affecting multiple areas of the gastrointestinal tract. …”
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Transcriptomic Analysis of Wheat Under Multi LED Light Conditions by Lei Sun, Ding Li, Chunhong Ma, Bo Jiao, Jiao Wang, Pu Zhao, Fushuang Dong, Shuo Zhou

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Sedum alfredii Hance: A cadmium and zinc hyperaccumulating plant by Mingying Liu, Ying Feng, Miao Wang, Xinglin Sun, Chen Yinfei Qi, Xiaoe Yang, Dayi Zhang

“…This also encourages studies on functional genes involved in metal transport, antioxidant, transcription regulation and stress response, providing candidates for genetic modification. …”
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Weighted Gene Co-Expression Network of Growth Differentiation-Related lncRNAs and mRNAs in Plectropomus leopardus by Jin GAO, Jinye LIU, Fuxiao CHEN, Yongbo WANG, Shuyuan FU

“…However, the quality of growth traits serves as a critical indicator for evaluating the economic value of fish aquaculture. Influenced by both genetic predispositions and environmental factors, these traits warrant investigation into the genetic mechanisms and regulatory strategies governing growth-related characteristics in farmed fish. …”
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