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Challenges in observing transcription–translation for bottom-up synthetic biology
Published 2025-01-01“…Synthetic biology aims to create a viable synthetic cell. However, to achieve this goal, it is essential first to gain a profound understanding of the cellular systems used to build that cell, how to reconstitute those systems in the compartments, and how to track their function. …”
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PlantReg: the reconstruction of links between transcription factor regulatory networks and biological processes under their control
Published 2025-01-01“…The pleiotropic effect of a gene is due to its participation in numerous biological processes involved in different traits. A widespread use of genome-wide sequencing of transcripts and transcription factor (TF) binding regions has made the following tasks relevant: unveiling pleiotropic effects of TFs based on the functions of their target genes; compiling the lists of TFs that regulate biological processes of interest; and describing the ways of TF functioning (their primary and secondary targets, higher order targets, TF interactions in the process under study). …”
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The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus
Published 2021-05-01“…Recently, it has been reported that some PHD family transcription factors are involved in the morphogenesis and AFB1 biological synthesis in A. flavus, but the role of Cti6, a PHD domain containing protein in A. flavus, is totally unknown. …”
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When HSFs bring the heat—mapping the transcriptional circuitries of HSF-type regulators in Candida albicans
Published 2025-01-01Subjects: “…transcription factors…”
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Androgen Receptor Regulates Transcription of the ZEB1 Transcription Factor
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New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels
Published 2025-02-01“…By examining the transcriptional responses of homologous genes in eelgrass, rice, and maize, we identified several groups of genes that are conserved in their response to salt stress. …”
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Systems biology analysis of the WOX5 gene and its functions in the root stem cell niche
Published 2016-09-01“…WUSCHEL RELATED HOMEOBOX 5 (WOX5) gene encodes the transcription factor, which is one of the key regulators, maintaining structure and functioning of the stem cell niche in plant root tips. …”
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Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional–Post-Transcriptional Regulatory Cross-Talk
Published 2025-01-01“…A very small subset of them is controlled by more than 20 microRNAs, and these hubs are highly enriched of pivotal transcription factors and regulatory proteins, strongly suggesting a complex interplay and a combinatorial effect between transcriptional and post-transcriptional gene control. …”
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Mechanisms of transcriptional regulation of ecdysone response
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Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN
Published 2024-09-01“…Discussion Our study sheds light on previously unexplored aspects of HSF1 biology, identifying it as a transcription factor capable of shaping the epigenetic landscape in the context of HCC. …”
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Epigenetic Mechanisms in the Transcriptional Regulation of Circadian Rhythm in Mammals
Published 2025-01-01“…These studies have enhanced our understanding of transcriptional regulation within biological circadian rhythms and the importance of circadian biology in human health. …”
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Optogenetic regulation of endogenous gene transcription in mammals
Published 2019-03-01“…In addition, such systems are of particular interest for genetics, molecular and cell biology. An ideal system should ensure tunable and reversible spatio-temporal control over transcriptional activity of a gene of interest. …”
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Chemical catalyst manipulating cancer epigenome and transcription
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Hairy transcriptional repression targets and cofactor recruitment in Drosophila.
Published 2004-07-01Get full text
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Neuroprotective Transcription Factors in Animal Models of Parkinson Disease
Published 2016-01-01Get full text
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