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    Challenges in observing transcription–translation for bottom-up synthetic biology by Vadim G. Bogatyr, Gijs J. L. Wuite

    Published 2025-01-01
    “…Synthetic biology aims to create a viable synthetic cell. However, to achieve this goal, it is essential first to gain a profound understanding of the cellular systems used to build that cell, how to reconstitute those systems in the compartments, and how to track their function. …”
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    PlantReg: the reconstruction of links between transcription factor regulatory networks and biological processes under their control by V. V. Lavrekha, N. A. Omelyanchuk, A. G. Bogomolov, E. V. Zemlyanskaya

    Published 2025-01-01
    “…The pleiotropic effect of a gene is due to its participation in numerous biological processes involved in different traits. A widespread use of genome-wide sequencing of transcripts and transcription factor (TF) binding regions has made the following tasks relevant: unveiling pleiotropic effects of TFs based on the functions of their target genes; compiling the lists of TFs that regulate biological processes of interest; and describing the ways of TF functioning (their primary and secondary targets, higher order targets, TF interactions in the process under study). …”
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    The PHD transcription factor Cti6 is involved in the fungal colonization and aflatoxin B1 biological synthesis of Aspergillus flavus by Zhang Mengjuan, Lin Guanglan, Pan Xiaohua, Song Weitao, Tan Can, Chen Xuan, Yang Yanling, Zhuang Zhenhong

    Published 2021-05-01
    “…Recently, it has been reported that some PHD family transcription factors are involved in the morphogenesis and AFB1 biological synthesis in A. flavus, but the role of Cti6, a PHD domain containing protein in A. flavus, is totally unknown. …”
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    New insights into the salt-responsive regulation in eelgrass at transcriptional and post-transcriptional levels by Huan Zhao, Huan Zhao, Xu Dong, Xu Dong, Dazuo Yang, Dazuo Yang, Qingchao Ge, Qingchao Ge, Peng Lu, Peng Lu, Chang Liu, Chang Liu

    Published 2025-02-01
    “…By examining the transcriptional responses of homologous genes in eelgrass, rice, and maize, we identified several groups of genes that are conserved in their response to salt stress. …”
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    Systems biology analysis of the WOX5 gene and its functions in the root stem cell niche by E. A. Oshchepkova, N. A. Omelyanchuk, M. S. Savina, T. Pasternak, N. A. Kolchanov, E. V. Zemlyanskaya

    Published 2016-09-01
    “…WUSCHEL RELATED HOMEOBOX 5 (WOX5) gene encodes the transcription factor, which is one of the key regulators, maintaining structure and functioning of the stem cell niche in plant root tips. …”
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    Integrated Analysis of microRNA Targets Reveals New Insights into Transcriptional–Post-Transcriptional Regulatory Cross-Talk by Simona Panni, Roberto Pizzolotto

    Published 2025-01-01
    “…A very small subset of them is controlled by more than 20 microRNAs, and these hubs are highly enriched of pivotal transcription factors and regulatory proteins, strongly suggesting a complex interplay and a combinatorial effect between transcriptional and post-transcriptional gene control. …”
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    Heat shock transcription factor 1 facilitates liver cancer progression by driving super‐enhancer‐mediated transcription of MYCN by Yizhe Liu, Qili Shi, Yue Su, Zhiao Chen, Xianghuo He

    Published 2024-09-01
    “…Discussion Our study sheds light on previously unexplored aspects of HSF1 biology, identifying it as a transcription factor capable of shaping the epigenetic landscape in the context of HCC. …”
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    Epigenetic Mechanisms in the Transcriptional Regulation of Circadian Rhythm in Mammals by Wei Mao, Xingnan Ge, Qianping Chen, Jia-Da Li

    Published 2025-01-01
    “…These studies have enhanced our understanding of transcriptional regulation within biological circadian rhythms and the importance of circadian biology in human health. …”
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    Optogenetic regulation of endogenous gene transcription in mammals by E. S. Omelina, A. V. Pindyurin

    Published 2019-03-01
    “…In addition, such systems are of particular interest for genetics, molecular and cell biology. An ideal system should ensure tunable and reversible spatio-temporal control over transcriptional activity of a gene of interest. …”
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