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PIWI proteins and piRNAs: key regulators of stem cell biology
Published 2025-02-01“…In this mini review, we discussed the functional roles of PIWI proteins and their associated small RNAs, piRNAs, in regulating gene expression within stem cell biology. Guided by piRNAs, these proteins transcriptionally and post-transcriptionally repress transposons using mechanisms such as the ping-pong amplification cycle and phasing to protect germline genomes. …”
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The Role of miR-378a in Metabolism, Angiogenesis, and Muscle Biology
Published 2015-01-01“…Embedding in the sequence of this transcriptional regulator of oxidative energy metabolism implies involvement of miR-378a in metabolic pathways, mitochondrial energy homeostasis, and related biological processes such as muscle development, differentiation, and regeneration. …”
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Elusive modes of Foxp3 activity in versatile regulatory T cells
Published 2025-01-01“…This new perspective offers an opportunity to reevaluate Foxp3’s activity modes in diverse biological contexts. By exploring this paradigm, we aim to unravel the fundamental principles of Treg cell biology.…”
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Decitabine Increases the Transcription of <i>RIG-I</i> Gene to Suppress the Replication of Feline Calicivirus and Canine Influenza Virus
Published 2025-01-01“…Developing novel antiviral drugs has always been a significant forefront in biological medicine research. Antiviral drugs can be extracted, purified, and synthesized from various biological sources and by different methods. …”
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Protocol for recombinant rabies virus titration by quantitative PCR
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CRISPR/Cas13a combined with reverse transcription and RPA for NoV GII.4 monitoring in water environments
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Activating Transcription Factor 5 Promotes Tumorigenic Capability in Cervical Cancer Through the Wnt/β-Catenin Signaling Pathway
Published 2025-01-01“…However, the biological function and precise mechanism of ATF5 in cervical cancer remain unclear. …”
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Probing the functional constraints of influenza A virus NEP by deep mutational scanning
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156
Cd99l2 regulates excitatory synapse development and restrains immediate-early gene activation
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Mina53 catalyzes arginine demethylation of p53 to promote tumor growth
Published 2025-02-01“…Summary: Arginine methylation is a common post-translational modification that plays critical roles in many biological processes. However, the existence of arginine demethylases that remove the modification has not been fully established. …”
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Effect of nanoparticulate CaCO3 on the biological properties of calcium silicate cement
Published 2025-01-01“…Abstract This study aimed to evaluate the effects of nanoparticulate CaCO3 (NPCC) on the biological properties of calcium silicate-based cements (CSCs), including their cytotoxicity, in vitro osteogenic activity, and interactions with rat femur tissue. …”
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