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Targeting Endothelial Adhesion Molecule Transcription for Treatment of Inflammatory Disease: A Proof-of-Concept Study
Published 2016-01-01“…We explored the concept of targeting endothelial adhesion molecule transcription during inflammation in a human system. …”
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Systems Biology Profiling of AMD on the Basis of Gene Expression
Published 2013-01-01“…Our analysis suggests a more complex transcriptional profile of the phenotypes than expected. …”
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The BES1/BZR1 transcriptional factor SlBES2 regulates photosynthetic apparatus in tomato fruit
Published 2025-01-01“…Results In this study, we identified a transcriptional factor SlBES2, the closest homolog of BES1 and BZR1 in tomato BES1 family, is highly expressed in fruit at mature green (MG) stage and exhibited transcriptional inhibition activity. …”
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GEPREP: A comprehensive data atlas of RNA-seq-based gene expression profiles of exercise responses
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Effects of Metalloporphyrins on Heme Oxygenase-1 Transcription: Correlative Cell Culture Assays Guide in Vivo Imaging
Published 2003-07-01“…However, certain Mps are phototoxic and some increase transcription of HO-1, the inducible HO isozyme. Therefore, effective development of this class of compounds as therapeutics for treating pathologic jaundice will require rapid and integrated biological screens to identify the most efficacious and safe Mps. …”
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Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology
Published 2025-01-01“…This review will highlight the dynamic roles of known RNA and post-transcriptional RNA epigenetic modifications within HTLV-1 biology, including viral <i>hbz</i>, long noncoding RNAs, microRNAs (miRNAs), transfer RNAs (tRNAs), R-loops, N6-methyladenosine (m<sup>6</sup>A) modifications, and RNA-based therapeutics and vaccines.…”
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Biological Aging and Venous Thromboembolism: A Review of Telomeres and Beyond
Published 2024-12-01“…In the last decade, advancements in omics methodologies provided insights into the molecular complexity of biological aging. Techniques such as high-throughput genomics, epigenomics, transcriptomics, proteomics, and metabolomics analyses identified and quantified numerous epigenetic markers, transcripts, proteins, and metabolites. …”
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The search for microRNAs potentially involved in the selfrenewal maintaining of laboratory rat pluripotent stem cells
Published 2018-04-01“…The use of bioinformatic and systems biology approaches is the first step, which is necessary for choosing candidates for the subsequent experimental studies. …”
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Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions
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