Effect of Kinases in Extracellular Vesicles from HIV-1-Infected Cells on Bystander Cells by Gifty A. Mensah, Anastasia Williams, Pooja Khatkar, Yuriy Kim, James Erickson, Alexandra Duverger, Heather Branscome, Kajal Patil, Hafsa Chaudhry, Yuntao Wu, Olaf Kutsch, Fatah Kashanchi

“…These kinases were shown to be biologically active and capable of phosphorylating substrates, and they modulated changes in the cell cycle dynamics of exposed cells. …”
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The Bile Acid Metabolism of Intestinal Microorganisms Mediates the Effect of Different Protein Sources on Muscle Protein Deposition in <i>Procambarus clarkii</i> by Xiaodi Xu, Xiaochuan Zheng, Qunlan Zhou, Cunxin Sun, Aimin Wang, Aimin Zhu, Yuanyuan Zhang, Bo Liu

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Insights Into the Role of Bmi‐1 Deregulation in Promoting Stemness and Therapy Resistance in Glioblastoma: A Narrative Review by Fatima Shaalan, Nissrine Ballout, Wafaa Takash Chamoun

“…Advancements in the field of epigenetics have expanded our understanding of cancer biology and helped explain the molecular heterogeneity of these tumors. …”
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Application of bacterioruberin from Arthrobacter sp. isolated from Xinjiang desert to extend the shelf-life of fruits during postharvest storage by Wasim Sajjad, Murad Muhammad, Sayed Muhammad Ata Ullah Shah Bukhari, Sumra Wajid Abbasi, Osama Abdalla Abdelshafy Mohamad, Yong-Hong Liu, Wen-Jun Li

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Kindlin-1 promotes gastric cancer cell motility through the Wnt/β-catenin signaling pathway by Jun-Ho Jang, Jiyoon Jung, Hyeon-Gu Kang, Woong Kim, Won-Jin Kim, Hana Lee, Ju Yeon Cho, Ran Hong, Jeong Won Kim, Joon-Yong Chung, Kyung-Hee Chun, Seok-Jun Kim

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Multi-omics approaches to deciphering complex pathological mechanisms of migraine: a systematic review by Jiaojiao Liu, Qiaosheng Ren, Boxuan Du, Xian Liu, Yuqiu An, Peichi Zhang, Lexi Li, Zhenhong Liu, Zhenhong Liu, Kegang Cao, Kegang Cao

“…Our search encompassed multiple databases including PubMed, EMBASE, the Web of Science Core Collection, the Cochrane Library, China National Knowledge Infrastructure, the Chinese Science and Technology Periodical Database, the Wanfang database, and the China Biology Medicine Database to cover studies from database inception until 20 March 2024., The scope of our review included various aspects of migraine such as ictal and interictal phases; episodic or chronic migraine; menstrual-related migraine; and migraine with or without aura (PROSPERO registration number: CRD42024470268).ResultsA total of 38 studies were ultimately included, highlighting a range of genetic variations, transcriptional abnormalities, protein function alterations, and disruptions in metabolic pathways associated with migraine.These multi-omics findings underscore the pivotal roles played by mitochondrial dysfunction, inflammatory responses, and oxidative stress in the pathophysiology of migraine.ConclusionMulti-omics approaches provide novel perspectives and tools for comprehending the intricate pathophysiology of migraine, facilitating the identification of potential biomarkers and therapeutic targets.Systematic Review Registrationhttps://www.crd.york.ac.uk/PROSPERO/display_record.php?…”
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Natural variation of OsWRKY23 drives difference in nitrate use efficiency between indica and japonica rice by Siyu Zhang, Zhe Ji, Wu Jiao, Chengbo Shen, Yaojun Qin, Yunzhi Huang, Menghan Huang, Shuming Kang, Xuan Liu, Shunqi Li, Zulong Mo, Ying Yu, Bingyu Jiang, Yanan Tian, Longfei Wang, Qingxin Song, Shaokui Wang, Shan Li

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Nanopore sequencing as a novel method of characterising anorexia nervosa risk loci by Natasha Berthold, Silvana Gaudieri, Sean Hood, Monika Tschochner, Allison L. Miller, Jennifer Jordan, Laura M. Thornton, Cynthia M. Bulik, Patrick Anthony Akkari, Martin A. Kennedy

“…Some of the variants identified in this way, such as the polymorphic SVA-D and poly-T STR, could contribute to mechanisms of phenotypic risk, through regulation of several neighbouring genes implicated in AN biology, and affect post-transcriptional processing of FOXP1, respectively. …”
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TGF-β induces cholesterol accumulation to regulate the secretion of tumor-derived extracellular vesicles by Dorival Mendes Rodrigues-Junior, Chrysoula Tsirigoti, Konstantina Psatha, Dimitris Kletsas, Michalis Aivaliotis, Carl-Henrik Heldin, Aristidis Moustakas

“…To this end, we used a large number of cancer cell models, coupled to EV cell biological assays, unbiased proteomic and transcriptomic screens, followed by signaling and cancer biology analyses, including drug resistance assays. …”
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Jasmonic acid improves cadmium tolerance in rice (Oryza sativa) by reducing the production of nitric oxide by Ji Bo Yang, Hao Yu Wang, Jing Huang, Chuan Jin Shan, Jing Yan, Chong Wei Zhong, Die Hu, Qiang Zhang, Ren Fang Shen, Xiao Fang Zhu, Da Li Zeng

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A novel human specific lncRNA MEK6-AS1 regulates adipogenesis and fatty acid biosynthesis by stabilizing MEK6 mRNA by Di Li, Yunhua Chen, Xingyu Zhu, Yanlei Yang, Hongling Li, Robert Chunhua Zhao

“…Results Human-specific lncRNA, we named it MEK6-AS1, was the most up-regulated transcript during adipogenic differentiation of MSCs. …”
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Estradiol-dependent and independent effects of FGF21 in obese female mice by T. V. Jakovleva, A. Yu. Kazantseva, A. D. Dubinina, N. Yu. Balybina, K. O. Baranov, E. N. Makarova, N. M. Bazhan

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Targeting MYCN upregulates L1CAM tumor antigen in MYCN-dysregulated neuroblastoma to increase CAR T cell efficacy by Laura Grunewald, Lena Andersch, Konstantin Helmsauer, Silke Schwiebert, Anika Klaus, Anton G. Henssen, Teresa Straka, Marco Lodrini, Sebastian G. Wicha, Steffen Fuchs, Falk Hertwig, Frank Westermann, Alice Vitali, Carlotta Caramel, Gabriele Büchel, Martin Eilers, Kathy Astrahantseff, Angelika Eggert, Uta E. Höpken, Johannes H. Schulte, Thomas Blankenstein, Kathleen Anders, Annette Künkele

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In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration by Georgios Petrogiannakis, Irene Guadagnino, Santiago Negueruela, Martina Di Guida, Elena Marrocco, Mariateresa Pizzo, Annalaura Torella, Mariateresa Zanobio, Marianthi Karali, Diego Luis Medina, Sabrina Carrella, Sandro Banfi

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Competence induction of homologous recombination genes protects pneumococcal cells from genotoxic stress by David De Lemos, Anne-Lise Soulet, Violette Morales, Mathieu Berge, Patrice Polard, Calum Johnston

“…Both recA and radA genes are basally expressed and transcriptionally induced during competence. In this study, we explored the importance of competence induction of recA and radA in transformation and genome maintenance. …”
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RNA-seq reproducibility of Pseudomonas aeruginosa in laboratory models of cystic fibrosis by Rebecca P. Duncan, Gina R. Lewin, Daniel M. Cornforth, Frances L. Diggle, Ananya Kapur, Dina A. Moustafa, Yasmin Hilliam, Jennifer M. Bomberger, Marvin Whiteley, Joanna B. Goldberg

“…This study confirms that different approaches to preparing and sequencing bacterial RNA libraries capture comparable transcriptional profiles, supporting investigators’ ability to leverage diverse RNA-seq data sets to advance their science.…”
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The role of lactylation in tumor growth and cancer progression by Khulood Al-Malsi, Khulood Al-Malsi, Khulood Al-Malsi, Sinan Xie, Sinan Xie, Sinan Xie, Yunshi Cai, Yunshi Cai, Yunshi Cai, Nader Mohammed, Kunlin Xie, Kunlin Xie, Kunlin Xie, Tian Lan, Tian Lan, Tian Lan, Hong Wu, Hong Wu, Hong Wu

“…BackgroundLactate’s perception of lactate has changed over the last 30 years from a straightforward metabolic byproduct to a complex chemical with important biological activities, such as signal transduction, gluconeogenesis, and mitochondrial respiration. …”
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The two-component system ArlRS is essential for wall teichoic acid glycoswitching in Staphylococcus aureus by Marieke M. Kuijk, Emma Tusveld, Esther Lehmann, Rob van Dalen, Iñigo Lasa, Hanne Ingmer, Yvonne Pannekoek, Nina M. van Sorge

“…Critical to S. aureus biology and pathogenesis are the cell wall-anchored glycopolymers wall teichoic acids (WTA). …”
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Alu Mobile Elements: From Junk DNA to Genomic Gems by Sami Dridi

“…However, recent findings that these mobile elements are transcribed, both as distinct RNA polymerase III transcripts and as a part of RNA polymerase II transcripts, suggest biological functions and refute the notion that Alus are biologically unimportant. …”
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Functional Analysis of DNMT1 SNPs (rs2228611 and rs2114724) Associated with Schizophrenia by Sonal Saxena, Pranay Amruth Maroju, Sumana Choudhury, Vidhya Chitta Voina, Poonam Naik, Kavitha Gowdhaman, Poornima Kkani, Kiranmai Chennoju, S. Ganesh Kumar, C. Ramasubramanian, G. Prasad Rao, Trinath Jamma, Kumar Pranav Narayan, K. Naga Mohan

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