Optimization of a Rabbit Dry Eye Model Induced by Topical Instillation of Benzalkonium Chloride by Carlos Carpena-Torres, Jesús Pintor, María Jesús Pérez de Lara, Fernando Huete-Toral, Almudena Crooke, Cristina Pastrana, Gonzalo Carracedo

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KLF4: a multifunctional nexus connecting tumor progression and immune regulation by Yunjie Ju, Wen Xiao, Bryan James Mathis, Ying Shi

“…Krüppel-like factors (KLFs) regulate various biological processes such as cell proliferation, migration, invasion, and differentiation as gene transcription factors. …”
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Review of the Structural and Dynamic Mechanisms of PPARγ Partial Agonism by Alice J. Kroker, John B. Bruning

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Unraveling the AMPK-SIRT1-FOXO Pathway: The In-Depth Analysis and Breakthrough Prospects of Oxidative Stress-Induced Diseases by Guangqi Guan, Yaoxing Chen, Yulan Dong

“…In oxidative stress conditions, AMPK, an energy sensor, activates SIRT1, which in turn stimulates the FOXO transcription factor. This cascade enhances mitochondrial function, reduces mitochondrial damage, and mitigates OS-induced cellular injury. …”
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Proteotranscriptomic Profiling of the Toxic Mucus of <i>Kulikovia alborostrata</i> (Pilidiophora, Nemertea) by Vasiliy G. Kuznetsov, Daria I. Melnikova, Sergey V. Shabelnikov, Timur Yu. Magarlamov

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Compiling Multicopy Single-Stranded DNA Sequences from Bacterial Genome Sequences by Wonseok Yoo, Dongbin Lim, Sangsoo Kim

“…The former, once transcribed, works as a template primer for reverse transcription by the latter. The resulting DNA is covalently linked to the upstream part of the RNA; this chimera is called multicopy single-stranded DNA (msDNA), which is extrachromosomal DNA found in many bacterial species. …”
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Two Mixed-Ligand Cu(II) Polymers: Treatment Activity on Acute Cerebral Infarction Combined with Alteplase by Wen-Ping Liu, Tao Xue, Yangchun Li, Ruoyu Cui

“…In addition to this, the real-time reverse transcription-polymerase chain reaction (RT-PCR) assay was conducted, and the inflammatory response in the brain was also determined.…”
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Expression and Characterization of the Novel Gene fr47 during Freezing in the Wood Frog, Rana sylvatica by Katrina J. Sullivan, Kyle K. Biggar, Kenneth B. Storey

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Identifying health risk determinants and molecular targets in patients with idiopathic pulmonary fibrosis via combined differential and weighted gene co-expression analysis by Abu Tayab Moin, Md. Asad Ullah, Jannatul Ferdous Nipa, Mohammad Sheikh Farider Rahman, Afsana Emran, Md. Minhazul Islam, Swapnil Das, Tawsif Al Arian, Mohammad Mahfuz Enam Elahi, Mukta Akter, Umme Sadea Rahman, Arnab Halder, Shoaib Saikat, Mohammad Jakir Hosen

“…Regulatory analysis highlighted interactions with transcription factors and microRNAs, suggesting potential mechanisms driving IPF pathogenesis. …”
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The impact of arbuscular mycorrhizal colonization on flooding response of Medicago truncatula by Vajiheh Safavi-Rizi, Vajiheh Safavi-Rizi, Helen Friedlein, Sayedhamid Safavi-Rizi, Franziska Krajinski-Barth

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CCL21-CCR7 blockade prevents neuroinflammation and degeneration in Parkinson’s disease models by Felipe Saceanu Leser, Flavio de Souza Júnyor, Iohanna Bianca Pagnoncelli, Anna Beatriz Delgado, Isabelle Medeiros, Ana Clara Campanelli Nóbrega, Brenda da Silva Andrade, Maiara Nascimento de Lima, Nícolas Emanoel da Silva, Laurent Jacob, Kevin Boyé, Luiz Henrique Medeiros Geraldo, Alessandra Mendonça Teles de Souza, Tatiana Maron-Gutierrez, Hugo Castro-Faria-Neto, Cristian Follmer, Carolina Braga, Gilda Angela Neves, Anne Eichmann, Luciana Ferreira Romão, Flavia Regina Souza Lima

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PSMA2 promotes chemo- and radioresistance of oral squamous cell carcinoma by modulating mitophagy pathway by Chun-I Wang, Cheng-Yi Chen, Ting-Wen Chen, Chun-Chia Cheng, Shu-Wen Hong, Tsung-You Tsai, Kai-Ping Chang

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Evidence that the domesticated fungus Leucoagaricus gongylophorus recycles its cytoplasmic contents as nutritional rewards to feed its leafcutter ant farmers by Caio Ambrosio Leal-Dutra, Lok Man Yuen, Bruno Augusto Maciel Guedes, Marta Contreras-Serrano, Pedro Elias Marques, Jonathan Zvi Shik

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A novel tissue culture method to produce professional antigen-presenting cells from rainbow trout in vitro by Nguyen T. K. Vo, PhD, Lital Sever, PhD, Brian Dixon, PhD, Niels C. Bols, PhD

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Full-length transcriptome analysis of male and female gonads in Japanese Eel (Anguilla japonica) by Jiangling Li, Jingjie Liang, Mengyang Wang, Yuewen Jiang, Wen Li, Mingxi Huang, Yan Huang, Yangjie Xie, Jianchun Chen, Tiansheng Chen

“…Abstract Background The Japanese eel (Anguilla japonica) holds significant economic value in East Asia, but limitations in understanding its reproductive biology have hindered advancements in artificial breeding techniques. …”
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Ganoboninketal C from Ganoderma boninense improves the efficacy of CDDP-based chemotherapy through inhibiting translesion DNA synthesis by Xiaolu Ma, Fei Yang, Ke Ma, Hongyan Shen, Junjie Han, Kai Wang, Yeran Yang, Jiawei Zhu, Ruiyuan An, Qilin Wang, Tie-Shan Tang, Bo Zhou, Hongwei Liu, Caixia Guo

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The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

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Genome-wide identification and characterization of WRKYs family involved in responses to Cylindrocarpon destructans in Panax notoginseng by Manqiao Li, Xiaoli Che, Qiwen Liang, Kuixiu Li, Guisheng Xiang, Xuyan Liu, Yan Zhao, Fugang Wei, Shengchao Yang, Guanze Liu

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Effect of Acupuncture on the Expression of Heme Oxygenase 1 and Inflammatory Factors in Rats with Intracerebral Hemorrhage by CHEN Qiuxin, KONG Ying, YU Tingting, ZHANG Yu, LIU Peng, ZHANG Xin

“…ObjectiveTo explore the effects of acupuncture at Baihui through Qubin acupoint on the expression of heme oxygenase 1 （HO-1） and inflammatory factors in rats with acute intracerebral hemorrhage from the levels of behavior, histology and molecular biology, so as to provide an experimental basis for clinical acupuncture in the treatment of intracerebral hemorrhage.MethodsA total of 108 Wistar male rats were randomly divided into sham operation group, model group, acupuncture + model group （referred to as acupuncture group）. …”
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The new technologies of high-throughput single-cell RNA sequencing by E. A. Vodiasova, E. S. Chelebieva, O. N. Kuleshova

“…The unique techniques for isolating, capturing and sequencing transcripts of tens of thousands of cells at a time are evolving now. …”
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