Quantification of Myocardial Biomarkers in Sudden Cardiac Deaths Using a Rapid Immunofluorescence Method for Simultaneous Biomarker Analysis by Matteo Antonio Sacco, Valerio Riccardo Aquila, Saverio Gualtieri, Roberto Raffaele, Maria Cristina Verrina, Lucia Tarda, Santo Gratteri, Isabella Aquila

“…Cardiac markers have been proposed as useful tools for this differentiation in forensic contexts. …”
Get full text

Surface water and flood-based agricultural systems: Mapping and modelling long-term variability in the Senegal river floodplain by Andrew Ogilvie, Cheickh Sadibou Fall, Ansoumana Bodian, Didier Martin, Laurent Bruckmann, Djiby Dia, Issa Leye, Papa Malick Ndiaye, Donissongou Dimitri Soro, Jean Homian Danumah, Jean-Claude Bader, Jean-Christophe Poussin

“…Occurrence maps and predictive models for annual flooded and cultivated areas based on upstream flows can support early warning tools, helping to prepare for extreme floods and droughts. …”
Get full text

Xpert Bladder Cancer Detection in Emergency Setting Assessment (XESA Project): A Prospective, Single-centre Trial by Federica Sordelli, Antonio Desai, Filippo Dagnino, Roberto Contieri, Sofia Giuriolo, Marco Paciotti, Vittorio Fasulo, Stefano Mancon, Davide Maffei, Pier Paolo Avolio, Giorgio Da Rin, Federica Maura, Elena Vanni, Davide Federico, Piergiuseppe Colombo, Giovanni Lughezzani, Nicolò Maria Buffi, Paolo Casale, Alberto Saita, Massiomo Lazzeri, Rodolfo Hurle, Antonio Voza

“…Our aim was to evaluate the clinical performance and economic implications of the Xpert BC Detection (BCD) test for patients presenting to the ED with haematuria to address the pressing need for more efficient and accurate diagnostic tools in this setting. Methods: We conducted a prospective single-centre observational study in the ED of a tertiary university hospital. …”
Get full text

Two new strains of Streptomyces with metabolic potential for biological control of pear black spot disease by Yi-Huang Chen, Jia-Xing Zhang, Yan Min, Yang Liu, Jian-Ming Wang, Lin-Quan Bai, Xiao-Xia Luo

“…The metabolic potential of the strain was assessed using a variety of approaches, including antiSMASH, COG, and KEGG databases, RGI tools, as well as the scanning of CAZY and plant-promoting genes. …”
Get full text

The Impact of Social Media for Hand Surgeons: A Prevalence and Correlation Study With Online and Academic Reputations by Sameer R. Khawaja, BS, Krishna N. Chopra, MA, Musab Gulzar, BS, Ozair R. Khawaja, HS, Shammah E. Udoudo, BS, Joseph G. Monir, MD, Michael B. Gottschalk, MD, Adrian L. Huang, MD, Nina Suh, MD, Eric R. Wagner, MD, MS

“…Using web-based marketing tools is still rare in hand surgery, especially among orthopedic surgeons. …”
Get full text

Gut microbiome-derived bacterial extracellular vesicles in patients with solid tumours by Surbhi Mishra, Mysore Vishakantegowda Tejesvi, Jenni Hekkala, Jenni Turunen, Niyati Kandikanti, Anna Kaisanlahti, Marko Suokas, Sirpa Leppä, Pia Vihinen, Hanne Kuitunen, Kaisa Sunela, Jussi Koivunen, Arja Jukkola, Ilja Kalashnikov, Päivi Auvinen, Okko-Sakari Kääriäinen, T. Peñate Medina, O. Peñate Medina, Juha Saarnio, Sanna Meriläinen, Tero Rautio, Raila Aro, Reetta Häivälä, Juho Suojanen, Mikael Laine, Pande Putu Erawijattari, Leo Lahti, Peeter Karihtala, Terhi S. Ruuska, Justus Reunanen

“…Introduction: Gut microbiome–derived nanoparticles, known as bacterial extracellular vesicles (bEVs), have garnered interest as promising tools for studying the link between the gut microbiome and human health. …”
Get full text

Co-designing action-oriented mental health conversations between care providers and ageing Canadians in the community: a participatory mixed-methods study protocol by Carrie McAiney, Paul Holyoke, Heather McNeil, Justine L Giosa, Elizabeth Kalles, Nelly D Oelke, Katie Aubrecht, Olinda Habib Perez

“…Phase 2 includes six co-design workshops with community providers (n=90) in rural and urban sites across three Canadian provinces to co-design tools, resources and processes for enabling the use of the adapted model as a conversation guide. …”
Get full text

High-resolution Cryo-EM Structure Determination of a-Synuclein—A Prototypical Amyloid Fibril by Juan Sanchez, Joshua Pierson, Collin Borcik, Chad Rienstra, Elizabeth Wright

“…We provide a detailed step-by-step protocol for high-resolution cryo-EM structure determination of a-syn fibrils using RELION and a series of specialized helical reconstruction tools that can be run within RELION. Finally, we detail how ChimeraX, Coot, and Phenix are used to build and refine a molecular model into the high-resolution cryo-EM map. …”
Get full text

Effects of ZnO nanoparticles concentration on the morphology and textural properties of ZnO/NiFe2O4 nanocomposite by Jimoh Oladejo Tijani, Augustine Innalegwu Daniel, Sarah Udenyi Onogwu, Ambali Saka Abdulkareem, Usman Ahmed Aminu, Marshall Keyster, Ashwil Klein

“…. • Nanocomposites was characterized using different analytical tools…”
Get full text

Patient-reported outcome measures to assess mental and physical health status, functionality, and quality of life in patients with major depression or schizophrenia by Luis San, Belen Arranz, Carlota Romans, Berta García, Marta Coromina, Sonia Ortiz, Miriam Vilaplana, Víctor Soto, Ruth Villaescusa, Joan Alvaros

“…Abstract Background Patient-reported outcomes measures (PROMs) are standardized self-administered tools that assess the patient’s opinion on the level of health, quality of life, and disability among other aspects. …”
Get full text

Designing a multi-epitope vaccine candidate against human rhinovirus C utilizing immunoinformatics approach by Tajul Islam Mamun, Tajul Islam Mamun, Md. Ahad Ali, Md. Nazmul Hosen, Jillur Rahman, Md. Anwarul Islam, Md. Golam Akib, Kamruz Zaman, Md. Masudur Rahman, Md. Masudur Rahman, Ferdaus Mohd Altaf Hossain, Ferdaus Mohd Altaf Hossain, Samir Ibenmoussa, Mohammed Bourhia, Turki M. Dawoud

“…Leveraging advanced immunoinformatics tools, we predicted epitopes for B-cells, Cytotoxic T lymphocytes, and Helper T lymphocytes, ensuring broad coverage across different HRV-C strains. …”
Get full text

Imaging abnormalities of the acromioclavicular joint and subacromial space are common in asymptomatic shoulders: a systematic review by Thomas Ibounig, Lasse Rämö, Romi Haas, Mark Jones, Teppo L. N. Järvinen, Simo Taimela, Sean Docking, Sharon Sanders, Rachelle Buchbinder

“…Clinical diversity precluded pooling. Population-based prevalence of acromioclavicular osteoarthritis (AC OA) ranged from 85% on MRI to 95% on X-ray. …”
Get full text

Safety and Efficacy of Incorporating Actellic^® 300 CS into Soil Wall Plaster for Control of Malaria Vectors in Rural Northeastern Uganda by Tonny Jimmy Owalla, Emmanuel Okurut, Kenneth Ssaka, Gonsaga Apungia, Barbara Cemeri, Andrew Akileng, Basil Ojakol, Mark J. I. Paine, Hanafy M. Ismail, Thomas G. Egwang

“…However, these control tools have important shortcomings including being donor-dependent, expensive, and often failing because of insufficient uptake. …”
Get full text

Mapping and assessment of land cover change and ecological stability: a case of three transects in Slovakia by Jana Vojteková, Matej Vojtek, Martin Boltižiar, František Petrovič, Matej Masný, Bohuslava Gregorová

“…Material and methods: Several methodological tools have been created to express the level of ecological stability of a given territory. …”
Get full text

Identification of an immunological signature of long COVID syndrome by Gisella Guerrera, Manolo Sambucci, Eleonora Timperi, Mario Picozza, Andrea Misiti, Andrea Misiti, Roberta Placido, Silvia Corbisiero, Silvia D’Orso, Andrea Termine, Carlo Fabrizio, Francesca Gargano, Sharon Eleuteri, Luisa Marchioni, Veronica Bordoni, Luigi Coppola, Marco Iannetta, Chiara Agrati, Giovanna Borsellino, Luca Battistini

“…These findings provide insights into LC pathogenesis and may support the development of diagnostic tools and targeted therapies.…”
Get full text

A protocol for mobilising novel finance models for collaborative health promotion and disease prevention initiatives: taking a smart capacitating investment approach in the Invest4... by Joanna Lane, Joanna Lane, Rhiannon T. Edwards, Balázs Babarczy, Holly Whiteley, Vidya Oruganti, Vidya Oruganti, Maureen Rutten-van Mölken, Caroline Costongs, Anant R. Jani, Sarah Wordsworth, Alison Maassen, Apostolos Tsiachristas, Jacob Davies, Bengt Stavenow, Jolanda van Vliet, Steve Wright, Steve Wright, Lina Papartyte, Jennifer Catherine Camaradou, Rositsa Koleva-Kolarova

“…Here we take that idea further by exploring the applicability of SCI to public health financing to improve population health and well-being.AimTo explore and develop innovative SCI models and tools that enable collaboration and investment across health ecosystems for enhanced health promotion and disease prevention, test them in diverse real-world settings, and create a roadmap for large-scale implementation.MethodsThe Invest4Health (I4H) project brings together transdisciplinary expertise in epidemiology, public health, health economics, population science, business management, finance, implementation and social sciences, digital health innovation, and regional health systems. …”
Get full text

Shorter Digestion Times of Donor Islets Is Associated With Better Islet Graft Function After Islet Transplantation by Chia-Hao Wang, Christopher Orr, Jeannette Hacker-Stratton, Mohamed El-Shahawy, Keiko Omori, Meirigeng Qi, Fouad Kandeel

“…Both PIR and GFI could be used by physicians as tools to monitor islet graft function and to guide supplementing the patient with exogenous insulin to prevent beta-cell exhaustion. …”
Get full text

Factors influencing access, quality and utilisation of primary healthcare for patients living with hypertension in West Africa: a scoping review by Tolib Mirzoev, Pablo Perel, Irene Akua Agyepong, Evelyn K Ansah, Kezia Naa Amerley Akosua Amarteyfio, Eugene Paa Kofi Bondzie, Veronika Reichenberger, Nana Efua Enyimayew Afun, Albert Kofi Mensah Cofie, Mary Pomaa Agyekum, Paul Lamptey

“…Meso (health system) factors include access to medications, tools, equipment and other supplies, out-of-pocket payments, availability of health insurance, health workers numbers, capacity and distribution. …”
Get full text

Novel Fusion Technique for High-Performance Automated Crop Edge Detection in Smart Agriculture by F. Martinez, James B. Romaine, P. Johnson, A. Cardona Ruiz, Pablo Millan Gata

“…Separating the crop from the background poses a significant challenge when using automated tools. To address this, a novel technique has been developed to automatically detect the vegetative area of lettuces, optimising time and eliminating subjectivity during crop inspections. …”
Get full text

Opportunities, challenges, and difficulties in NMR-based metabolomics applied to neovascular age-related macular degeneration (nAMD) patient follow-up by M. Schoumacher, M. Schoumacher, V. Lambert, M. Campas, P. Blaise, B. Locht, M. Thys, E. Duchateau, E. Cavalier, E. Cavalier, J.-M. Rakic, A. Noël, P. de Tullio, P. de Tullio

“…Both multivariate and univariate statistical approaches tailored for longitudinal data were employed to identify biomarkers correlating metabolomic changes with ocular alterations during disease progression.Results and DiscussionDespite a rigorous analytical workflow enabling precise quantification of over 60 metabolites and the application of advanced statistical tools for longitudinal data, achieving consistent results across the cohort proved challenging. …”
Get full text