Spatial identification of regions exposed to multi-hazards at the pan-European level by T.-E. Antofie, T.-E. Antofie, S. Luoni, A. Tilloy, A. Sibilia, S. Salari, G. Eklund, D. Rodomonti, C. Bountzouklis, C. Corbane

“…<p>The European Commission Disaster Risk Management Knowledge Centre (DRMKC) has developed and hosts a web platform, the Risk Data Hub (RDH), designed to facilitate access to and sharing of curated, EU-wide risk data, tools, and methodologies, ultimately supporting disaster risk management (DRM) initiatives. …”
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Large-scale flood risk assessment in data-scarce areas: an application to Central Asia by P. Ceresa, G. Bussi, S. Denaro, G. Coccia, P. Bazzurro, P. Bazzurro, M. Martina, M. Martina, E. Fagà, C. Avelar, M. Ordaz, B. Huerta, O. Garay, Z. Raimbekova, K. Abdrakhmatov, S. Mirzokhonova, S. Mirzokhonova, V. Ismailov, V. Belikov

“…</p> <p>The largest relative (to the total exposed value) expected annual damages are found in Kazakhstan and Tajikistan, with values above 6 ‰. …”
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Family-focused intervention programme to foster adolescent mental health and well-being: protocol for a multicountry cluster randomised factorial trial (FLOURISH Phase 2) by Heather M Foran, Marija Raleva, Nina Heinrichs, Graham Moore, Yulia Shenderovich, Xiang Zhao, Judith Simon, Antonio Piolanti, Viorel Babii, Janina Mueller, Franziska Waller, Dennis Wienand, Swetha Sampathkumar, Ivo Kunovski

“…Effective and scalable interventions are urgently needed to address these challenges.Methods and analysis This protocol outlines a multicountry cluster randomised factorial trial, implemented according to the multiphase optimisation strategy (Phase 2), which evaluates the effectiveness and costs of three add-on components for the Parenting for Lifelong Health for Parents and Teens programme: adolescent mental health tools based on UNICEFs Helping Adolescents Thrive comics, adolescent peer support based on UNICEFs ‘I Support My Friends’ intervention and engagement booster designed to enhance attendance and programme completion through incentives. …”
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Simulation of Image-Guided Microwave Ablation Therapy Using a Digital Twin Computational Model by Frankangel Servin, Jarrod A. Collins, Jon S. Heiselman, Katherine C. Frederick-Dyer, Virginia B. Planz, Sunil K. Geevarghese, Daniel B. Brown, William R. Jarnagin, Michael I. Miga

“…Emerging computational tools such as healthcare digital twin modeling are enabling the creation of patient-specific surgical planning, including microwave ablation to treat primary and secondary liver cancers. …”
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Research trends in glioma chemoradiotherapy resistance: a bibliometric analysis (2003–2023) by Shishi Yu, Jinya Wu, Yuan Jing, Ping Lin, Lang Lang, Yifan Xiong, Wangzhong Chen, Wenhua Liu, Changpeng Sun, Yuntao Lu

“…This study aims to systematically evaluate the research landscape, identify emerging hotspots, and provide guidance for future investigations.MethodsArticles on glioma chemoradiotherapy resistance published between 2003 and 2023 were retrieved from the Web of Science Core Collection, resulting in 4,528 publications. Bibliometric tools, including VOSviewer, CiteSpace, and R packages such as bibliometrix and ggplot2, were used to analyze co-authorship networks, keyword evolution, and citation bursts to identify collaboration patterns, thematic developments, and influential contributions.ResultsPublication output increased significantly between 2013 and 2022, peaking at 650 articles in 2022. …”
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Serological insights from SARS-CoV-2 heterologous prime and boost responses in Thailand by Daniel Ward, Lapasrada Pattarapreeyakul, Rujiraporn Pitaksalee, Naphatcha Thawong, Waritta Sawaengdee, Suthida Tuntigumthon, Catriona Patterson, Kevin Tetteh, Susana Campino, Panadda Dhepakson, Surakameth Mahasirimongkol, Taane G. Clark

“…Overall, our study underscores the necessity for vaccine (re-)development and the creation of serological tools to monitor vaccine performance.…”
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The global energy challenge: second-generation feedstocks on marginal lands for a sustainable biofuel production by Claudio Russo, Valerio Cirillo, Nausicaa Pollaro, Fabio Terribile, Andrea Chiodini, Albino Maggio

“…To fully exploit this option, it will be critical to calibrate plant growth models to estimate the potential biofuel production on marginal land from second-generation feedstock and to create tools for a more rational management of this land. …”
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Quantifying the potential value of entomological data collection for programmatic decision-making on malaria control in sub-Saharan African settings by Nora Schmit, Hillary M. Topazian, Matteo Pianella, Giovanni D. Charles, Peter Winskill, Penelope A. Hancock, Ellie Sherrard-Smith, Katharina Hauck, Thomas S. Churcher, Azra C. Ghani

“…Abstract Background The availability of many tools for malaria control leads to complex decisions regarding the most cost-effective intervention package based on local epidemiology. …”
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Two rare cases of primary clear cell adenocarcinoma of the urethra: clinical experience, case report and literature review by Bohao Jiang, Jiyuan Hu, Benqiao Wang, Xujia Liu, Ling Tong, Yitong Xu, Hao Zhang

“…Unfortunately, it is difficult to differentiate primary clear-cell adenocarcinoma of the urethra from other urethral tumors due to similar clinical features. However, imaging tools such as CT, MRI, and cystoscopy are adjunctive in confirming diagnoses. …”
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Impacts of intestinal microbiota metabolite trimethylamine N-oxide on cardiovascular disease: a bibliometric analysis by Xiaohui Leng, Xiaohui Leng, Xiunan Wei, Jun Wang, Xiaodong Yao, Miaomiao Zhang, Dajuan Sun, Junwei Liang, Lili Chi, Yan Cheng

“…BackgroundTrimethylamine N-oxide (TMAO), a metabolite dependent on intestinal microbiota, is closely related to the emergence, progression, and prognosis of cardiovascular disease (CVD), and has received increasing attention in recent years.ObjectiveThe current research hotspots and future development trends in TMAO and CVD field are found through bibliometrics analysis, which provides reference for further study.MethodsThe bibliometrics tools VOSviewer and CiteSpace were used to analyze the publications from the Web of Science Core Collection (WOSCC) database. …”
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Investigating the implementation of a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates: a multisite quality improvement i... by Eliane M Shore, Elizabeth Miazga, Cheyanne Reed, Alisha Olsthoorn, Isabella Fan, Eliya Zhao, Jodi Shapiro, Amanda Cipolla, Modupe Tunde-Byass

“…Objectives To study the effect of implementing a Trial of Labour After Caesarean (TOLAC) delivery bundle with respect to decreasing caesarean delivery rates across five hospitals.Design Prospective quality improvement study.Setting Five Canadian hospital sites participated, two academic centres and three community hospitals, with annual delivery rates ranging from 2500 to 7500 per site.Participants All obstetrical patients with a singleton gestation in cephalic presentation and only one previous caesarean delivery were included.Interventions A TOLAC bundle was introduced at each hospital site, consisting of three main interventions: (1) education for healthcare providers, (2) a TOLAC discussion sheet and (3) patient educational tools.Primary and secondary outcome measures The primary outcome was the caesarean delivery rate in eligible patients. …”
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A Study on Material Removal Rate in Powder-Mixed Electro-Discharge Machining Utilizing Integrated Experimental and Computational Fluid Dynamics Analysis by Nguyen Huu-Phan, V.S. Ganachari, Shailesh Shirguppikar, P.B. Gavali, S.S. Deshmukh, P.S. Jadhav, L. Selvarajan, Nguyen Duc-Toan, M.V. Pachore

“…These simulations serve as invaluable tools in elucidating the underlying mechanisms governing the machining process, providing insights into the intricate interplay between electrical discharges, fluid flow, and particulate dynamics. …”
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Effect of combined aerobic exercise and resistance training on postmenopausal women with type 2 diabetes: a systematic review and meta-analysis by Vitor Engracia Valenti, André dos Santos Chagas, Peter Chedraui, Ingrid Soares de Souza, Andrey Alves Porto, Isabel Cristina Esposito Sorpreso, Jose Maria Soares Júnior, Juliana Zangirolami-Raimundo, David M. Garner, Rodrigo Daminello Raimundo

“…The outcomes of interest were the blood glucose levels, insulin secretion, homeostasis model assessment-insulin resistance index (HOMA-IR) and glycated hemoglobin (HbA1c). Risk of Bias tools and GRADE were obligatory.Results Three studies were included (83 participants). …”
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No Relation Between Cognitive Impairment, Physical Disability and Serum Biomarkers in a Cohort of Progressive Multiple Sclerosis Patients by Bartosz Gajewski, Iwona Karlińska, Małgorzata Domowicz, Igor Bednarski, Mariola Świderek-Matysiak, Mariusz Stasiołek

“…Despite significant efforts, there is still an existing need to identify diagnostic tools that would enable fast and reliable detection of the progressive stage of multiple sclerosis (MS) and help in monitoring the disease course and/or treatment effects. …”
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Artificial Intelligence in Cardiac Surgery: Transforming Outcomes and Shaping the Future by Vasileios Leivaditis, Eleftherios Beltsios, Athanasios Papatriantafyllou, Konstantinos Grapatsas, Francesk Mulita, Nikolaos Kontodimopoulos, Nikolaos G. Baikoussis, Levan Tchabashvili, Konstantinos Tasios, Ioannis Maroulis, Manfred Dahm, Efstratios Koletsis

“…<b>Results:</b> A total of 121 studies were included in this review. …”
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Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…The intervention also provided tools to help journalists with reporting, including a Tip Sheet and list of expert contacts in health and medicine. …”
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Life after prostate cancer diagnosis: protocol for a UK-wide patient-reported outcomes study by David H Brewster, Victoria Cairnduff, Eila Watson, Amy Downing, Adam W Glaser, Penny Wright, William Cross, Conan Donnelly, Anna Gavin, Carol Rivas, Richard Wagland, Peter Selby, Luke Hounsome, Therese Kearney, Rebecca Mottram, Majorie Allen, Oonagh McSorley, Hugh Butcher, Paul Kind, James W H Catto, Dyfed Huws, Emma McNair, Lauren Matheson, Johana Nayoan, Mike Horton, Jessica Corner, Julia Verne

“…Second, separate cohorts will be surveyed once and the design will include evaluation of the acceptability of online survey tools. A comprehensive patient-reported outcome measure has been developed using generic and specific instruments with proven psychometric properties and relevance in national and international studies. …”
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DepRescribing inapprOpriate Proton Pump InhibiTors (DROPIT): study protocol of a cluster-randomised controlled trial in Swiss primary care by Stefan Neuner-Jehle, Katharina Tabea Jungo, Sven Streit, Sven Trelle, Nicolas Rodondi, Carole Elodie Aubert, Kristie Rebecca Weir, Enriqueta Vallejo-Yagüe, Samantha Chan, Marie Roumet, Pascal Juillerat, Sofia Carolina Zambrano Ramos, Jennifer Inauen, Angela Edith Schulthess-Lisibach, Renata Vidonscky Lüthold, Clémentine Tombez, Martina Zangger, Flurina Jenal, Yvonne Mattmann, Christof Bieri, Michaela Barbier

“…Clusters are randomised 1:1 to either the intervention group or the control group.Interventions The intervention components consist of deprescribing tools including educational material, decision aids for both participants and GPs, and additional trainings for GPs only. …”
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Biomarker Investigation Using Multiple Brain Measures from MRI Through Explainable Artificial Intelligence in Alzheimer’s Disease Classification by Davide Coluzzi, Valentina Bordin, Massimo W. Rivolta, Igor Fortel, Liang Zhan, Alex Leow, Giuseppe Baselli

“…This lays the foundation for bioengineering advancements in developing more comprehensive and trustworthy DL models, potentially enhancing their applicability as diagnostic support tools for neurodegenerative diseases.…”
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Alzheimer’s disease diagnosis using rhythmic power changes and phase differences: a low-density EEG study by Juan Wang, Juan Wang, Jiamei Zhao, Xiaoling Chen, Xiaoling Chen, Bowen Yin, Xiaoli Li, Xiaoli Li, Ping Xie, Ping Xie

“…ObjectivesThe future emergence of disease-modifying treatments for dementia highlights the urgent need to identify reliable and easily accessible tools for diagnosing Alzheimer’s disease (AD). Electroencephalography (EEG) is a non-invasive and cost-effective technique commonly used in the study of neurodegenerative disorders. …”
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