Challenges in Bootstrapping a Start-Up Venture: Keenga Research Turning the Tables on Venture Capitalists by Prescott C. Ensign, Anthony A. Woods

“…This case study chronicles the timeline of a new venture – Keenga Research. Keenga Research has a novel proposition that it is seeking to introduce to the market. …”
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Temporally and Spatially Controlled Age-Related Prostate Cancer Model in Mice by Sen Liu, Keyi Shen, Zixuan Li, Seleste Rivero, Qiuyang Zhang

“…Thus, it is essential to develop a method by which the PCa initiation and progression timeline can be strictly controlled to mimic human physiological conditions. …”
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Four Decades of <i>Bacillus</i> Biofertilizers: Advances and Future Prospects in Agriculture by Xinmai Wu, Yan Liu, Baolei Jia, Lili Tao, Han Li, Jingbang Wang, Ziqi Yuan, Xiaobao Sun, Yanlai Yao

“…We segmented the research timeline into three distinct phases, each marked by varying growth rates and research foci. …”
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Pilot study of extended-release lorcaserin for cocaine use disorder among men who have sex with men: A double-blind, placebo-controlled randomized trial. by Glenn-Milo Santos, Janet Ikeda, Phillip Coffin, John E Walker, Tim Matheson, Matthew McLaughlin, Jennifer Jain, Eric Vittinghoff, Steven L Batki

“…<h4>Objective</h4>To determine if men who have sex with men (MSM) with cocaine use disorder (CUD) and actively-using cocaine could be enrolled and retained in a pharmacologic intervention trial of lorcaserin-a novel 5-HT2cR agonist-and determine the degree to which participants would adhere to study procedures.…”
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Assessment of maternal health and behavior during pregnancy in the HEALthy Brain and Child Development Study: Rationale and approach by Kelly K. Gurka, Heather H. Burris, Lucia Ciciolla, Claire D. Coles, Suena H. Massey, Sharlene Newman, Vidya Rajagopalan, Lynne M. Smith, Anna Zilverstand, Gretchen Bandoli

“…Pregnancy, chronic and acute health conditions, family mental health, and healthcare utilization were assessed using existing and novel measures. Maternal mental health was assessed with the Edinburgh Postpartum Depression Scale, select items in the DSM-5 Self-Rated Level-1 and −2 Cross-Cutting Symptom Measures, and the National Stressful Events Survey-PTSD Short Scale. …”
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Post Covid-19 Syndromes, The Time line of Covid by Nadia Shams, Zaid Umar, Lubna Meraj, Neelam Ayub, Muhammad Waseem, Kazim Abbas Virk

“… BACKGROUND & OBJECTIVES: Novel corona virus has claimed significant mortality and morbidity. …”
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Comprehensive analysis of publications concerning combinations of immunotherapy and targeted therapies for hepatocellular carcinoma: a bibliometric study by Biling Gan, Lei Wu, Shunan Zhou, Zhihong Chen, Fan Wu, Lianqun Xu, Zhenrong Chen, Honghui Ma, Peijia He, Dan Fang, Ning Shi

“…This study provides a bibliometric overview of these therapeutic combinations, evaluating their development and impact.MethodsA rigorous selection process was applied to relevant literature from Web of Science, followed by in-depth bibliometric analyses— including timeline visualization, burst detection, and co-occurrence analysis—using CiteSpace and VOSviewer. …”
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A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024 by Saijilafu, Saijilafu, Ling-Chen Ye, Huanyi Li, Haokun Li, Xinyi Lin, Kehui Hu, Zekai Huang, Chimedragchaa Chimedtseren, Linjun Fang, Saijilahu, Ren-Jie Xu

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Identification of potential COVID-19 main protease inhibitors using structure-based pharmacophore approach, molecular docking and repurposing studies by Daoud Safa, Alabed Shada J., Dahabiyeh Lina A.

“…The current outbreak of novel coronavirus (COVID-19) infections urges the need to identify potential therapeutic agents. …”
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Targeting Soluble Amyloid Oligomers in Alzheimer’s Disease: A Hypothetical Model Study Comparing Intrathecal Pseudodelivery of mAbs Against Intravenous Administration by Manuel Menendez-Gonzalez

“…This hypothetical study aimed to model amyloid dynamics in early-to-moderate Alzheimer’s disease (AD) and compare the efficacy of IV mAn with intrathecal pseudodelivery, a novel method that confines mAbs in a subcutaneous reservoir for selective amyloid clearance in cerebrospinal fluid (CSF) without systemic exposure. …”
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A mixed-method investigation of the root causes of construction project delays in Afghanistan by Mohammad Basheer Ahmadzai, Kunhui Ye

“…A key contribution of this research is its novel focus on security-related causes of construction project delays. …”
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Edge-Preserving Probabilistic Downsampling for Reliable Medical Segmentation in Resource-Constrained Environments by Shahzad Ali, Yu Rim Lee, Soo Young Park, Won Young Tak, Soon Ki Jung

“…This study introduces a novel approach, Edge-Preserving Probabilistic Downsampling (EPD), designed to retain critical details and bridge the performance gap between networks trained on original and downsampled resolutions. …”
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Improving drug repositioning with negative data labeling using large language models by Milan Picard, Mickael Leclercq, Antoine Bodein, Marie Pier Scott-Boyer, Olivier Perin, Arnaud Droit

“…Abstract Introduction Drug repositioning offers numerous advantages, such as faster development timelines, reduced costs, and lower failure rates in drug development. …”
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