The Evaluation of Restored Proximal Contact Areas with Four Direct Adherent Biomaterials: An In Vitro Study by Elena-Cristina Marcov, Mihai Burlibașa, Narcis Marcov, Florentina Căminișteanu, Andreea Angela Ștețiu, Mircea Popescu, Radu-Cătălin Costea, Raluca Mariana Costea, Liliana Burlibașa, Andi Ciprian Drăguș, Maria Antonia Ștețiu, Dana Cristina Bodnar

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Two-group bubble size distribution evolution in vertical two-phase flow: Mechanistic model development and evaluation in a tight-lattice rod bundle by Xiao Yao, Zhang Hengwei, Yan Xu, Gu Hanyang

“…The model has been tested on a tight-lattice rod bundle using experimental data, with deviations of less than 5% and 15% for G₁ and G₂ flow, respectively. …”
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Re-performing African Literature: A Review of Owonibi’s Translation of three Yoruba Literary works into English – Chief Gaa, Delusion of Grandeur and The Tight Game by Titilope Oluwaseun Oriola

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Brain microvascular endothelial cells differentiated from a Friedreich’s Ataxia patient iPSC are deficient in tight junction protein expression and paracellularly permeable by Frances M. Smith, Daniel J. Kosman

“…We previously identified decreased levels of F-actin and tight junction (TJ) proteins, which coincided with paracellular permeability in an FXN shRNA-mediated knockdown immortalized human brain microvascular endothelial cell (BMVEC) model. …”
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Caco2/HT-29 In Vitro Cell Co-Culture: Barrier Integrity, Permeability, and Tight Junctions’ Composition During Progressive Passages of Parental Cells by Elena Donetti, Paola Bendinelli, Margherita Correnti, Elena Gammella, Stefania Recalcati, Anita Ferraretto

“…The intestinal epithelial barrier (IEB) consists of enterocytes through tight junctions and mucus-secreting cells and can undergo physiological modifications throughout life. …”
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Early Radiation-Induced Changes in Lung Tissue and Intercellular Junctions: Implications for Tissue Repair and Fibrosis by Ekaterina S. Karetnikova, Alexandra A. Livanova, Arina A. Fedorova, Alexander G. Markov

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CD14 and ALPK1 Affect Expression of Tight Junction Components and Proinflammatory Mediators upon Bacterial Stimulation in a Colonic 3D Organoid Model by Pascal Brooks, Talke zur Bruegge, Erin C. Boyle, Stefan Kalies, Santiago Nahuel Villarreal, Andrea Liese, André Bleich, Manuela Buettner

“…Intestinal barrier integrity can be influenced by CD14, whereas to date, the role of ALPK1 in maintaining barrier function remains unknown. We used colon-derived 3D organoids, first characterised for growth, proliferation, stem cell markers, and expression of tight junction (TJ) components using qPCR and immunohistochemistry. …”
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Regulation of mitochondrial oxidative phosphorylation through tight control of cytochrome c oxidase in health and disease – Implications for ischemia/reperfusion injury, inflammato... by Lucynda Pham, Tasnim Arroum, Junmei Wan, Lauren Pavelich, Jamie Bell, Paul T. Morse, Icksoo Lee, Lawrence I. Grossman, Thomas H. Sanderson, Moh H. Malek, Maik Hüttemann

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Loss of Mpdz impairs ependymal cell integrity leading to perinatal‐onset hydrocephalus in mice by Anja Feldner, M Gordian Adam, Fabian Tetzlaff, Iris Moll, Dorde Komljenovic, Felix Sahm, Tobias Bäuerle, Hiroshi Ishikawa, Horst Schroten, Thomas Korff, Ilse Hofmann, Hartwig Wolburg, Andreas von Deimling, Andreas Fischer

“…LCAM1 and MPDZ (MUPP1) are the only known human gene loci associated with non‐syndromic hydrocephalus. To investigate functions of the tight junction‐associated protein Mpdz, we generated mouse models. …”
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Cinnamaldehyde Alleviates Salmonellosis in Chicks by Regulating Gut Health by Lizi Yin, Luxin Li, Xue Lv, Fengsheng Sun, Yuyun Dai, Yingzi Guo, Shihao Peng, Chenyu Ye, Xiaoxia Liang, Changliang He, Gang Shu, Ping Ouyang

“…RT-qPCR showed that CA up-regulated the mRNA expression of tight-junction proteins (claudin-1, occludin-1, and zo-1, <i>p</i> < 0.05). …”
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Establishment of a novel probe-based RT-qPCR approach for detection and quantification of tight junctions reveals age-related changes in the gut barriers of broiler chickens. by J Sophia von Buchholz, Ivana Bilic, Jörg R Aschenbach, Michael Hess, Taniya Mitra, Wageha A Awad

“…Tight junctions (TJs) play a dominant role in gut barrier formation, therefore, resolving the structures of TJs in any animal species is crucial but of major importance in fast growing broilers. …”
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Integrative Approach to Managing Childhood Asthma: Case Study by Rekha V. Shinde, Ashish Varma, Saurabh Deshmukh, Trupti Thakre

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Faecal mucoprotein MUC2 is decreased in multiple sclerosis and is associated with mucin degrading bacteriaResearch in context by Luke A. Schwerdtfeger, Federico Montini, Tanuja Chitnis, Laura M. Cox, Howard L. Weiner

“…Interpretation: Taken together, these findings suggest reduced gut barrier function in MS which is linked to increased mucin degrading bacteria. …”
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Impact of yeast-derived nucleotides supplementation in drinking water on production performance and gut health indicators in broiler chickens by Vera Perricone, Marcello Comi, Nida Irshad, Cristina Lecchi, Yasmine Dadi, Lucia Aidos, Paola Cremonesi, Bianca Castiglioni, Filippo Biscarini, Giovanni Savoini, Alessandro Agazzi

“…This study investigated the effects of yeast-derived nucleotides (YN) supplementation via drinking water on growth performance, intestinal morphology, barrier function, and cecal microbiota in broiler chickens. …”
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Ligilactobacillus salivarius LZZAY01 accelerated autophagy and apoptosis in colon cancer cells and improved gut microbiota in CAC mice by Wenhong Yang, Tao Li, Shixiang An, Rong Chen, Yuxin Zhao, Jiaxian Cui, Mingyu Zhang, Jingkun Lu, Yunpeng Tian, Lili Bao, Pengwei Zhao

“…L. salivarius LZZAY01 improved CAC via suppressing the growth of colon cancer cells, promoting autophagy and apoptosis, enhancing intestinal tight junctions, reducing intestinal barrier degradation, modifying the gut microbiota abundance, and decreasing inflammatory reactions.IMPORTANCEAlthough similar probiotics have been shown to have anticancer potential in colorectal cancer (CRC), there is a paucity of research related to the preventive function of probiotics against CRC. …”
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Bupleuri Radix Ameliorates Vascular Inflammation in Human Umbilical Vein Endothelial Cells via Modulation of Tight Junction Protein Expression and Inhibition of Nuclear Factor-κB A... by Min Yeong Kim, Eun Jin Bang, Yung Hyun Choi, Su Hyun Hong

“…However, it is unclear whether BR can regulate vascular endothelial function under inflammatory conditions induced by interleukin-1β (IL-1β), a key proinflammatory cytokine. …”
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Tannic Acid and Ethacridine Lactate Attenuate Markers of Stress-Induced Intestinal Barrier Dysfunctions in Murine Small Intestinal Organoids by Louisa Filipe Rosa, Steffen Gonda, Nadine Roese, Stephan C. Bischoff

“…TA is thought to modulate gastrointestinal barrier function, but the underlying mechanisms and whether Eta has similar effects remains unclear. (2) Methods: to investigate the effects of TA and Eta on the intestinal barrier, stress responses were induced in murine intestinal organoids by lipopolysaccharide (LPS) exposure or withdrawal of growth factors from cell culture medium (GF_Red). …”
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Influence of the size of iron nanoclusters on their magnetization by Л.И. Квеглис, Ф.М. Носков, А.А. Калитова, Р.Т. Насибуллин, А.В. Нявро, А.Н. Черепанов, А.Е. Олехнович, Д.Н. Сапрыкин

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HDAC3 regulates the diurnal rhythms of claudin expression and intestinal permeability by Hunter Christopher, Jianglin Zhang, Sarah Olanrewaju Oladejo, Samskrathi Aravinda Sharma, Zheng Kuang

“…Circadian rhythms play an essential role in the regulation of intestinal absorption and barrier function. Tight junctions, including claudins, are fundamental components of the intestinal epithelial barrier. …”
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Mechanisms of bacterial-to-host interaction and their disorders at inflammatory bowel diseases by Ye. A. Poluektova, O. S. Lyashenko, A. V. Korolev, O. S. Shifrin, V. T. Ivashkin

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