A Fog Computing-Based Cost-Effective Smart Health Monitoring Device for Infectious Disease Applications by Saranya Govindakumar, Vijayalakshmi Sankaran, Paramasivam Alagumariappan, Bhaskar Kosuru Bojji Raju, Daniel Ford

“…These signs and symptoms, which collectively inflict considerable strain on healthcare systems and people’s quality of life, comprise, but are not restricted to, congestion, shortage of breath, tightness in the chest, and a decrease in lung function. …”
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The Marine Food Chain in Relation to Biodiversity by Andrew R.G. Price

“…While there is probably functional redundancy within groups, the effects of species loss on ecosystem performance cannot be easily predicted. …”
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Morphological Alterations in the Kidney Following Different Durations of Warm Ischemia: An Experimental Study by Ulugbek Abduganiev, Muhammadaziz Aliev, Pulat Sultanov

“…After the laparotomy, the wound was sutured tightly. Each group was further subdivided into three subgroups (6 rats in each subgroup) to be euthanized by decapitation on Days 3, 7, and 14 of the experiment. …”
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Cryo-EM structure of the BLOC-3 complex provides insights into the pathogenesis of Hermansky-Pudlak syndrome by Xin Yong, Guowen Jia, Qin Yang, Chunzhuang Zhou, Sitao Zhang, Huaqing Deng, Daniel D. Billadeau, Zhaoming Su, Da Jia

“…Despite its importance, the structure and molecular function of BLOC-3 remains elusive. Here, we report the Cryo-EM structure of human BLOC-3 at 3.2 Å resolution. …”
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New insight into the significance of KLF4 PARylation in genome stability, carcinogenesis, and therapy by Zhuan Zhou, Furong Huang, Indira Shrivastava, Rui Zhu, Aiping Luo, Michael Hottiger, Ivet Bahar, Zhihua Liu, Massimo Cristofanilli, Yong Wan

“…Here, we demonstrated that KLF4 is tightly regulated by poly(ADP‐ribosyl)ation (PARylation). …”
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Equine neutrophils selectively release neutrophil extracellular traps in response to chemical and bacterial agonists by Breanna J. Sheahan, Breanna J. Sheahan, Alicia G. Schubert, William Schubert, M. Katie Sheats, M. Katie Sheats, Lauren V. Schnabel, Lauren V. Schnabel, Jessica M. Gilbertie, Jessica M. Gilbertie, Jessica M. Gilbertie

“…Thus, NET formation must be tightly controlled and represents an opportunity for therapeutic interventions. …”
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Upregulation of long noncoding RNA zinc finger antisense 1 enhances epithelial–mesenchymal transition in vitro and predicts poor prognosis in glioma by Qiao-Li Lv, Shu-Hui Chen, Xue Zhang, Bao Sun, Lei Hu, Qiang Qu, Yuan-Tao Huang, Gui-Hua Wang, Yan-Ling Liu, Ying-Ying Zhang, Hong-Hao Zhou

“…Zinc finger antisense 1 is a novel long noncoding RNA whose clinical significance, biological function, and underlying mechanism are still undetermined in glioma. …”
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Nuclear talin-1 provides a bridge between cell adhesion and gene expression by Alejandro J. Da Silva, Hendrik S.E. Hästbacka, Mikael C. Puustinen, Jenny C. Pessa, Jens C. Luoto, Erika Sundström, Benjamin T. Goult, Guillaume Jacquemet, Eva Henriksson, Lea Sistonen

“…To determine the functional impact of nuclear TLN1, we expressed a TLN1 fusion protein containing a nuclear localization signal. …”
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Genetically predicted brain cortical structure mediates the causality between insulin resistance and cognitive impairment by Chaojuan Huang, Yuyang Zhang, Mingxu Li, Qiuju Gong, Siqi Yu, Zhiwei Li, Mengmeng Ren, Xia Zhou, Xiaoqun Zhu, Zhongwu Sun

“…BackgroundInsulin resistance is tightly related to cognition; however, the causal association between them remains a matter of debate. …”
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A Huluwa phosphorylation switch regulates embryonic axis induction by Yao Li, Yun Yan, Bo Gong, Qianwen Zheng, Haiyan Zhou, Jiarui Sun, Mingpeng Li, Zhao Wang, Yaohui Li, Yunjing Wan, Weixi Chen, Shiqian Qi, Xianming Mo, Anming Meng, Bo Xiang, Jing Chen

“…Abstract Embryonic axis formation is essential for patterning and morphogenesis in vertebrates and is tightly regulated by the dorsal organizer. Previously, we demonstrated that maternally derived Huluwa (Hwa) acts as a dorsal determinant, dictating axis formation by activating β-catenin signaling in zebrafish and Xenopus. …”
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A three-dimensional reconstruction method of coal mine tunnel fused with LiDAR and IMU by Qinghua MAO, Jianquan CHAI, Yanzhang CHEN, Xusheng XUE, Chuanwei WANG

“…In this method, the residual function of the lidar observation model and the prior state deviation of the IMU prediction model are tightly coupled through iterative kalman filter, and a more accurate posteriori state is obtained through state update, which provides reliable pose estimation for the degraded environment. …”
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Genome-Wide Identification of <i>MsICE</i> Gene Family in <i>Medicago sativa</i> and Expression Analysis of the Response to Abiotic Stress by Baiji Wang, Qianning Liu, Wen Xu, Yuying Yuan, Muzhapaer Tuluhong, Jinqiu Yu, Guowen Cui

“…Therefore, we studied the function of ICE TFs in alfalfa. We identified 11 <i>MsICE</i> genes from the alfalfa genome and classified them into two groups. …”
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SK4 potentially modulates the alternative splicing profile associated with papillary thyroid cancer development in BHT101 cells by Alimujiang Wupuer, Xuekelaiti Kuerban, Gong Ye

“…Recent studies demonstrated the potassium channel protein SK4 participates in the progression of many cancers, while it lacks the molecular mechanism study for SK4 function. In this study, we performed functional and molecular explorations for SK4 by overexpressing its level in thyroid cancer BHT101 cells. …”
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Echocardiographic diagnosis of interarterial AAOCA in children: a framework integrating anatomical landmarks and systolic dysfunction for risk assessment by Rui Hu, Xuming Mo, Shanliang Zhu, Jun Chen, Ying Tang, Yumei Xu

“…Postoperatively, 10/11 cases achieved normal cardiac function. Conclusions Echocardiography provides a clinically actionable protocol for preoperative AAOCA diagnosis by integrating anatomical markers (Acute deviation, parallel course) and functional metrics (LVEF, wall motion). …”
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Calcium Signaling Dynamics in Vascular Cells and Their Dysregulation in Vascular Disease by Chang Dai, Raouf A. Khalil

“…Also, the individual Ca²⁺ handling pathways could be integrated to function in a regenerative, capacitative, cooperative, bidirectional, or reciprocal feed-forward or feed-back manner. …”
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An integrated structural and biophysical approach to study carbon metabolism in Mycobacterium tuberculosis by Evelyn Y.-W. Huang, Francis Kuang, Haozhe Wu, Chai Xin Yu, Xiaoxu Chen, Glenda Vasku, Le Thao Anh Nguyen, Katherine J. Jeppe, Anna K. Coussens, Brooke X.C. Kwai, Ivanhoe K.H. Leung

“…Many of these enzymes are tightly regulated by feedback mechanisms. To fully understand their roles and modulation, it is crucial to investigate the relationship between their structure, catalytic mechanism, and function. …”
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NEDD4L contributes to ferroptosis and cell growth inhibition in esophageal squamous cell carcinoma by facilitating xCT ubiquitination by Zhen Chen, Weilong Wang, Jinghan Hou, Can Gao, Meili Song, Zijun Zhao, Ruirui Guan, Jingsheng Chen, Huicheng Wu, Siti Razila Abdul Razak, Tao Han, Junbo Zhang, Lidong Wang, Nor Hazwani Ahmad, Xiumin Li

“…Emerging evidence indicated xCT function is tightly controlled by posttranslational modifications, especially ubiquitination. …”
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Alloimmune Causes of Recurrent Pregnancy Loss: Cellular Mechanisms and Overview of Therapeutic Approaches by Cristina Uța, Alexandru Tîrziu, Elena-Larisa Zimbru, Răzvan-Ionuț Zimbru, Marius Georgescu, Laura Haidar, Carmen Panaitescu

“…Successful pregnancy requires a tightly regulated balance between pro-inflammatory and anti-inflammatory immune responses. …”
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Case Report: Giant pheochromocytoma complicated by takotsubo syndrome: a case of emergency robot-assisted left adrenalectomy and multidisciplinary management by Jia Miao, Jia Miao, Xuanhan Hu, Xuanhan Hu, Ting Wang, Feng Liu, Dahong Zhang, Haibin Wei

“…Postoperatively, cardiac function normalized within three months, and catecholamine levels returned to baseline. …”
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OPA1 and disease-causing mutants perturb mitochondrial nucleoid distribution by J. Macuada, I. Molina-Riquelme, G. Vidal, N. Pérez-Bravo, C. Vásquez-Trincado, G. Aedo, D. Lagos, P. Yu-Wai-Man, R. Horvath, T. J. Rudge, B. Cartes-Saavedra, V. Eisner

“…Cells from ADOA patients show impaired mitochondrial fusion, cristae structure, bioenergetic function, and mitochondrial DNA (mtDNA) integrity. …”
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