The effect of wet cupping on reactive airway dysfunction syndrome (RADS) caused by early exposure to chlorine gas: A randomized clinical trial by khatereh Akbari Mashak, Khosro Agin, Elham Emaratkar, Mohammad Gholami Fesharaki, Hasan Namdar

“…WCT significantly improved symptoms (dyspnea, cough, chest tightness, etc.) within the first hour (p=0.003) compared to the controls, with no future significant changes during the first week and first-month post-WCT. …”
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ZmPGIP1 regulates stem strength by enhancing lignin and cellulose biosynthesis in Arabidopsis thaliana by Juan-Juan Xu, Jia Zhou, Zheng Cai, Jin-Liang Sun, You-Zhi Li, Xian-Wei Fan

“…Polygalacturonase inhibiting proteins (PGIPs) are typical leucine-rich repeat (LRR) proteins that inhibit the activity of polygalacturonase (PG) in pathogens, but their function in promoting to plant stem development has been less studied. …”
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Uga3 influences nitrogen metabolism in Saccharomyces cerevisiae by modulating arginine biosynthesis by Nicolás Urtasun, Sebastián Aníbal Muñoz, Martín Arán, Mariana Bermúdez-Moretti

“…Nitrogen metabolism in Saccharomyces cerevisiae is tightly regulated to optimize the utilization of available nitrogen sources. …”
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Photomediated ion dynamics enables multi-modal learning, memory and sensing in ultralow-voltage organic electrochemical device by Guocai Liu, Wei Wen, Cong Shan, Haojie Huang, Yao Zhao, Yangshuang Bian, Yunlong Guo, Hui Huang, Yunqi Liu

“…Due to the efficient separation of photogenerated charges within the heterojunction, the holes can be tightly trapped by anions at the photoactive layer–channel interface. …”
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Genome-Wide Identification of DNA Methyltransferases (Dnmts) in Fish and Its Potential Roles During Sex Change in Blackhead Seabream by Sixin Guo, Binwei Duan, Jianchao Chen, Mingyang Cui, Canbei You, Hanyin Wei, Xiazi Huang, Li Deng, Kai Zhang

“…The cellular DNA methylation level is tightly regulated by DNA methyltransferases (Dnmt). …”
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Effectiveness of Scapular Stabilization Versus Non-Stabilization Stretching on Shoulder Range of Motion, a Randomized Clinical Trial by Alan J Howell, Andrew Burchett, Nicholas Heebner, Cody Walker, Alec Baunach, Asia Seidt, Tim L Uhl

“…# Background Previous research has demonstrated the benefits of both stabilization and non-stabilization of the scapula during stretching in individuals with posterior shoulder tightness, but limited evidence exists in patients with shoulder pain…”
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Autophagy: An Overview of Molecular Mechanisms and Its Therapeutic Implications for Health and Disease by Hourolein Arab, Mohammad Reza Mofid, Mahboube Rahmati, Elahe Gharehkhani, Armin Mokhtariye, Mohammad Shokrzadeh

“…This review provides a comprehensive analysis of the mechanisms and functions of autophagy, exploring its association with various human diseases. …”
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Cleavage site heterogeneity at the pre-mRNA 3′-untranslated region regulates gene expression in oxidative stress response by Feba Shaji, Jamshaid Ali, Rakesh S. Laishram

“…The endonucleolytic cleavage step of the eukaryotic mRNA 3′-end processing is considered imprecise, which leads to heterogeneity of cleavage site (CS) with hitherto unknown function. Contrary to popular belief, we show that this imprecision in the cleavage is tightly regulated, resulting in the CS heterogeneity (CSH) that controls gene expression in antioxidant response. …”
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Ultrasonic characteristics of inserted central catheter related fibroblastic sleeve by Zhifei Ben, Jue Wang, Jinyong Zhan, Kaiying Xu

“…Patients required the ultrasound evaluation due to local swelling and pain, abnormal coagulation function, lack of response to flushing of saline and heparin, or before extubation. …”
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Niemann - Pick C2 regulates steroid hormone secretion and lipid deposition in chicken follicular granulosa cells by Ruihao Yu, Shuo Wei, Felix Kwame Amevor, Liuting Wu, Dan Xu, Zheliang Liu, Kunlong Qi, Yingjie Wang, Gang Shu, Xiaoling Zhao

“…Follicular development is tightly regulated by the coordinated action of multiple hormones and complex gene regulatory networks in granulosa cells, which play a crucial role in egg production and fertility in hens. …”
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Understanding the cellular dynamics, engineering perspectives and translation prospects in bioprinting epithelial tissues by Irem Deniz Derman, Joseph Christakiran Moses, Taino Rivera, Ibrahim T. Ozbolat

“…Most organs in the body contain an epithelial tissue component, where the tightly connected, organ-specific epithelial cells organize into cysts, invaginations, or tubules, thereby performing distinct to endocrine or exocrine secretory functions. …”
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An Hfq-dependent post-transcriptional mechanism fine tunes RecB expression in Escherichia coli by Irina Kalita, Ira Alexandra Iosub, Lorna McLaren, Louise Goossens, Sander Granneman, Meriem El Karoui

“…This fine-tuning Hfq-mediated mechanism might have the underlying physiological function of maintaining RecB protein levels within an optimal range.…”
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Hydrogen-bonded supramolecular polymer networks for effective removal of perchlorate in water via clustered hydrogen-bonding by Jintao Tian, Xing Han, Hao-Ran Yang, Juan Liu, Jin-Fa Chen, Tai-Bao Wei, Hong Yao, Wen-Juan Qu, Bingbing Shi, Qi Lin

“…The HBPC network is constructed by an A,A’-bis-pyridyl-hydrazone-phenyl conjugate-functionalized pillar[5]arene (PYP5), which self-assembles via the formation of clustered hydrogen-bonds. …”
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Temporal Dynamics of Retinal Inflammation Following Blast Exposure in a Ferret Model by Rex Jeya Rajkumar Samdavid Thanapaul, Chetan Pundkar, Gaurav Phuyal, Manoj Y. Govindarajulu, Ashwathi Menon, Joseph B. Long, Peethambaran Arun

“…Ferrets (n = 40) were subjected to two tightly coupled blasts (20 psi) using an advanced blast simulator. …”
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Quantitative Risk Assessment of Tropical Cyclone-Induced Extreme Waves on Marine Aquaculture Based on Physical Vulnerability by Jiayi Fang, Siying Zhu, Wanchao Bian, Shuiqing Li, Wankang Yang, Zhihui Mo, Siru Yang, Peng Yun, Yuhan Yan, Xianwu Shi, Junfeng Xu, Tangao Hu

“…Subsequently, by constructing the failure probability of net cage structures under different significant wave heights, we established a physical vulnerability function relating wave height to failure probability. …”
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MLKL‒OPTN axis regulates herpesvirus‐induced neurological sequelae by Ilina Bhattacharya, Rashmi Kadam, Tejabhiram Yadavalli, Chandrashekhar D. Patil, Hemant Borase, Ipsita Volety, Sergey Kalinin, Douglas L. Feinstein, Henry C. Tseng, Deepak Shukla

“…Methods and Results This study investigates new molecular dynamics following HSV‐1 infection, uncovering the pivotal role of the mixed lineage kinase domain‐like (MLKL) protein. Beyond its known function in necroptosis, MLKL was found to control HSV‐1 transport into the nucleus, tightly regulated by Optineurin (OPTN). …”
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The Interplay of Molecular Factors and Morphology in Human Placental Development and Implantation by Ioana Vornic, Victor Buciu, Cristian George Furau, Flavia Zara, Dorin Novacescu, Alina Cristina Barb, Alin Adrian Cumpanas, Silviu Constantin Latcu, Ioan Sas, Denis Serban, Talida Georgiana Cut, Cristina Stefania Dumitru

“…The placenta is a vital organ that supports fetal development by mediating nutrient and gas exchange, regulating immune tolerance, and maintaining hormonal balance. Its formation and function are tightly linked to the processes of embryo implantation and the establishment of a robust placental-uterine interface. …”
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Heavy Metals Distribution and Source Identification in Contaminated Agricultural Soils: Isotopic and Multi-Model Analysis by Tingting Mu, Benyi Cao, Min Yang, Xinhong Gan, Lin Chen, Xiaohan Wang, Ming Li, Yuanyuan Lu, Jian Xu

“…Heavy metal pollution in agricultural soil has been tightly associated with anthropogenic emissions. Although there are many studies that focus on a regional scale, the source identification of heavy metal contamination on a field scale around industrial areas remains unclear. …”
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Expression of LTR and LINE1 transposable elements defines atypical teratoid/rhabdoid tumor subtypes by Martin V. Hamann, Shweta Godbole, Maisha Adiba, Sabrina M. Leddy, Jelena Navolić, Ghazaleh Tabatabai, Daniel J. Merk, Ulrike C. Lange, Julia E. Neumann

“…Transcriptional activity of transposable elements (TEs), like LINE1s and LTRs, is tightly linked with human cancers as a direct consequence of lifting epigenetic repression over TEs. …”
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Pitolisant alleviates brain network dysfunction and cognitive deficits in a mouse model of Alzheimer’s disease by Yang Zou, Linhan Yang, Jiahui Zhu, Jihua Fan, Hanrun Zheng, Xiang Liao, Zhiqi Yang, Kuan Zhang, Hongbo Jia, Arthur Konnerth, Yan-jiang Wang, Chunqing Zhang, Yun Zhang, Sunny C. Li, Xiaowei Chen

“…Abstract Histamine H3 receptor (H3R) antagonists regulate histamine release that modulates neuronal activity and cognitive function. Although H3R is elevated in Alzheimer’s disease (AD) patients, whether H3R antagonists can rescue AD-associated neural impairments and cognitive deficits remains unknown. …”
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