Revisiting the role of Annexins in membrane trafficking by Thomas Grewal, Volker Gerke, Jesper Nylandsted, Carles Rentero, Carlos Enrich

“…Over the years, structural, biochemical and cell imaging studies have revealed that annexins facilitate the organization of membrane domains to allow the formation of tight interactions between membranes destined to fuse. …”
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Large system study of chalcopyrite and pyrite flotation surfaces based on SCC-DFTB parameterization method by Jianhua Chen, Yibing Zhang

“…In this study, we employed the self-consistent charge density functional tight-binding (SCC-DFTB) parameterization method to develop a parameter set, CuFeOrg, which includes the interactions between Cu-Fe-C-H-O-N-S-P-Zn elements, to investigate the surface interactions in large-scale flotation systems of chalcopyrite and pyrite. …”
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Fucoidan as a therapeutic agent for ulcerative colitis: mechanisms of action and modulation of the gut microbiota by Yating Zhang

“…FCD enhances intestinal barrier integrity via upregulation of tight junction proteins (Claudin-1, ZO-1) and mucin MUC2 expression, while remodeling gut microbial ecology through enrichment of SCFAs-producing bacteria (e.g., Ruminococcaceae) and suppression of pathogens (Escherichia coli, Candida albicans). …”
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Dynamic multidimensional pressure deformation in the waist-abdomen region of young women by Xing Zheng, Xiaoyun Liu, Yunyun Hu, Yuqing Shi, Mengyun Zhang, Jun Zhang

“…This research offers novel insights for optimizing clothing design, enhancing the functional design and comfort design, and contributes to improving the body and clothing simulation.…”
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Exploring Lymphangioma: A Synthesis of the Literature and Clinical Perspectives by Nada Bochor, Parshotam Gera

“…Computational atomistic molecular dynamics (MD) and density functional tight binding (DFTB) techniques may offer an experimental approach to future therapeutic targets. …”
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Ste12/Fab1 phosphatidylinositol-3-phosphate 5-kinase is required for nitrogen-regulated mitotic commitment and cell size control. by David Cobley, Lenka Hálová, Marie Schauries, Adrian Kaczmarek, Mirita Franz-Wachtel, Wei Du, Karsten Krug, Boris Maček, Janni Petersen

“…Tight coupling of cell growth and cell cycle progression enable cells to adjust their rate of division, and therefore size, to the demands of proliferation in varying nutritional environments. …”
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Interactions between the Nse3 and Nse4 components of the SMC5-6 complex identify evolutionarily conserved interactions between MAGE and EID Families. by Jessica J R Hudson, Katerina Bednarova, Lucie Kozakova, Chunyan Liao, Marc Guerineau, Rita Colnaghi, Susanne Vidot, Jaromir Marek, Sreenivas R Bathula, Alan R Lehmann, Jan Palecek

“…Our work provides new insights into the interactions, evolution and functions of the enigmatic MAGE proteins.…”
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Barriers and Strategies for Oral Peptide and Protein Therapeutics Delivery: Update on Clinical Advances by Kshitis Chandra Baral, Ki Young Choi

“…In particular, functional biomaterials, active targeting, and lymphatic transport strategies have provided new platforms for oral PP delivery. …”
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“Italy System” as a Case of Innovative Economic Diplomacy by R. O. Raynkhardt

“…Finally, a special emphasis is put on the tight link between instruments of "soft power" and economic diplomacy and their institutional usage, which has deep historical roots.…”
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Cytoprotection of the Gastric Mucosa and Eradication Therapy of <i>Helicobacter Pylori</i> Infection: Points of Conjugation by A. S. Trukhmanov, D. E. Rumyantseva, T. L. Lapina

“…H. pylori has a negative effect on all levels of protection of the gastroduodenal mucosa, for example, it affects the secretion of mucins, disrupts the tight junction proteins functioning. Eradication of H. pylori infection eliminates its negative effects. …”
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The Lyme disease bacterium, Borrelia burgdorferi, stimulates an inflammatory response in human choroid plexus epithelial cells. by Derick Thompson, Jordyn Sorenson, Jacob Greenmyer, Catherine A Brissette, John A Watt

“…The main functions of the choroid plexus (CP) are the production of cerebral spinal fluid (CSF), the formation of the blood-CSF barrier, and regulation of immune response. …”
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Data-driven prediction and design of bZIP coiled-coil interactions. by Vladimir Potapov, Jenifer B Kaplan, Amy E Keating

“…Testing more than 132 candidate protein complexes using a fluorescence resonance energy transfer assay confirmed the formation of tight and selective heterodimers between the designed peptides and their targets. …”
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Melatonin Mitigates Sarcopenic Obesity via Microbiota and Short‐Chain Fatty Acids: Evidence From Epidemiologic and In Vivo Studies by Xiaoxing Mo, Lihui Shen, Xinyu Wang, Wenqing Ni, Linyan Li, Lili Xia, Hongjie Liu, Ruijie Cheng, Lin Wen, Jian Xu, Liegang Liu

“…MLT ameliorated obesity‐related metabolic disorders (p < 0.05), poor muscle mass (p < 0.05), strength (p < 0.05) and function (p < 0.05) and muscle atrophy (p < 0.05) in HFD‐fed rats. …”
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Unlocking iron: nutritional origins, metabolic pathways, and systemic significance by Zoha Imtiaz Malik, Muhammad Umer Ghafoor, Syed Hassan Bin Usman Shah, Juweria Abid, Umar Farooq, Abdul Momin Rizwan Ahmad, Abdul Momin Rizwan Ahmad

“…Iron is a vital micronutrient, involved in numerous cellular functions including DNA synthesis, oxygen transport, energy generation, and immunity enhancement. …”
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Different roles of astrocytes in the blood–brain barrier during the acute and recovery phases of stroke by Jialin Cheng, Yuxiao Zheng, Fafeng Cheng, Chunyu Wang, Jinhua Han, Haojia Zhang, Xin Lan, Chuxin Zhang, Xueqian Wang, Qingguo Wang, Changxiang Li

“…This comprehensive review explores the physiological and pathological morphological and functional changes in astrocytes and the blood–brain barrier in ischemic stroke. …”
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TNFα alters occludin and cerebral endothelial permeability: Role of p38MAPK. by Yawen Ni, Tao Teng, Runting Li, Agnes Simonyi, Grace Y Sun, James C Lee

“…Occludin is a key tight junction (TJ) protein in cerebral endothelial cells (CECs) playing an important role in modulating blood-brain barrier (BBB) functions. …”
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Production, purification and characterization of recombinant, full-length human claudin-1. by Nicklas Bonander, Mohammed Jamshad, Dominik Oberthür, Michelle Clare, James Barwell, Ke Hu, Michelle J Farquhar, Zania Stamataki, Helen J Harris, Karsten Dierks, Timothy R Dafforn, Christian Betzel, Jane A McKeating, Roslyn M Bill

“…The transmembrane domain proteins of the claudin superfamily are the major structural components of cellular tight junctions. One family member, claudin-1, also associates with tetraspanin CD81 as part of a receptor complex that is essential for hepatitis C virus (HCV) infection of the liver. …”
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Centromere protection requires strict mitotic inactivation of the Bloom syndrome helicase complex by María Fernández-Casañas, Eleftheria Karanika, Umit Aliyaskarova, Tomisin Olukoga, Alex D. Herbert, Antony W. Oliver, Matthew Day, Adrijana Crncec, Kok-Lung Chan

“…Here, we show a centromere protection pathway in human mitotic cells, heavily reliant on a tight spatiotemporal control of the BTRR complex.…”
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PVA and PVP nanofibers combined with Helichrysum italicum oil preserve skin cell interactions, elasticity and proliferation by Diletta Serra, Giuseppe Garroni, Sara Cruciani, Donatella Coradduzza, Aleksei Pashchenko, Evzen Amler, Giorgio Pintore, Pietro Parisse, Rosanna Satta, Fernanda Martini, Mauro Tognon, Antonio Brunetti, Carlo Ventura, Margherita Maioli

“…We showed the potential application of Polyvinyl acetate (PVA) and Polyvinylpyrrolidone (PVP) combined with Helichrysum italicum oil (HO) in wound healing. During this process, Tight junctions (TJs) play a crucial role in maintaining skin integrity. …”
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Dendrobium officinale polysaccharide attenuates type 2 diabetes in mice model by modulating gut microbiota and alleviating intestinal mucosal barrier damage by Xiaoxia Chen, Chun Chen, Changyang Ma, Wenyi Kang, Junlin Wu, Xiong Fu

“…Interestingly, the study found that DOP reduced intestinal inflammation and oxidative stress levels, significantly up-regulated the mRNA expression of tight junction proteins Claudin-1, Occludin and zonula occluden-1 (ZO-1), and ameliorated intestinal epithelial damage. …”
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