Lonicerae flos and turmeric extracts alleviate necrotic enteritis in broilers by modulating gut-liver health and microbiota by Xingbo Liu, Yunru Ji, Huiyuan Lv, Zhong Wang, Zengpeng Lv, Yuming Guo, Wei Nie

“…LTE enhanced intestinal morphology and up-regulated the expression of tight junction protein genes (CLDN1, TJP1) and MUC2, suppressed pro-inflammatory cytokine and myeloperoxidase (MPO) levels, and minimized endotoxin (ET) accumulation in NE broilers (P < 0.05). …”
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The Multifunctional Catalytic Hemoglobin from <i>Amphitrite ornata</i>: Protocols on Isolation, Taxonomic Identification, Protein Extraction, Purification, and Characterization by Anna L. Husted, Victoria R. Sutton, Lauren A. Presnar, R. Kevin Blackburn, Joseph L. Staton, Stephen A. Borgianini, Edward L. D’Antonio

“…The multifunctional catalytic hemoglobin from the terebellid polychaete <i>Amphitrite ornata</i>, also named dehaloperoxidase (<i>Ao</i>DHP), utilizes the typical oxygen transport function in addition to four observed activities involved in substrate oxidation. …”
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Modulatory effects of synbiotic blend on selected human fecal bacteria and TNFα + LPS-induced inflammation in human intestinal epithelial cells by Anita Rawat, Arka Bhattacharya, Rupa Tharu, Ruchika Maurya, Sanjay Kumar Bhadada, Mahendra Bishnoi, Kanthi Kiran Kondepudi

“…Synbiotic formulations (combinations of prebiotics and probiotics) are known to improve microbial balance, promote gut barrier function and to exhibit immunomodulatory properties. …”
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Soybean bioactive peptide supplementation improves gut health and metabolism in broiler chickens by Han Peng, Xiaoyan Song, Jialei Chen, Xia Xiong, Li Yang, Chunlin Yu, Mohan Qiu, Zengrong Zhang, Chenming Hu, Shiliang Zhu, Bo Xia, Jiangxian Wang, Zhuxiang Xiong, Longhuan Du, Chaowu Yang

“…In conclusion, SBP is a potential feed additive that can improve intestinal morphology, enhance intestinal immunity and barrier function, optimize the structure of the intestinal microbiota, and enhance metabolic function.…”
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Ibrutinib disrupts blood-tumor barrier integrity and prolongs survival in rodent glioma model by Sanghee Lim, Minhye Kwak, Jeonghan Kang, Melissa Cesaire, Kayen Tang, Robert W. Robey, William J. E. Frye, Baktiar Karim, Donna Butcher, Martin J. Lizak, Mahalia Dalmage, Brandon Foster, Nicholas Nuechterlein, Charles Eberhart, Patrick J. Cimino, Michael M. Gottesman, Sadhana Jackson

“…Yet additional research is required to understand ibrutinib’s effect on BTB function. In this study, we detail baseline BTK expression in glioma cells and its surrounding vasculature, then measure endothelial junctional expression/function changes with varied ibrutinib doses in vitro. …”
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Optimal estimates of trace distance between bosonic Gaussian states and applications to learning by Lennart Bittel, Francesco Anna Mele, Antonio Anna Mele, Salvatore Tirone, Ludovico Lami

“…In this work, we fully resolve this question by demonstrating that if the first and second moments are known up to an error $\varepsilon$, the trace distance error on the state also scales as $\varepsilon$, and this functional dependence is optimal. To prove this, we establish tight bounds on the trace distance between two Gaussian states in terms of the norm distance of their first and second moments. …”
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Glovebox-CT to Enable 3D Imaging of Reactive or Hazardous Samples by Nick Brierley, Darius Zanke, Luke Peche, Peter Habenschaden

“…With a leakage rate of Class 1 according to ISO 10684-2, the glovebox functions as an ultra-tight containment, ensuring the integrity and safety needed for handling challenging materials, whilst the radiation enclosure ensures operators and bystanders are protected from X-rays during scanning. …”
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Existence and Phase Structure of Random Inverse Limit Measures by B. J. K. Kleijn

“…Analogous to Kolmogorov’s theorem for the existence of stochastic processes describing random functions, we consider theorems for the existence of stochastic processes describing random measures as limits of inverse measure systems. …”
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Intersegmental eye-head-body interactions during complex whole body movements. by Christoph von Laßberg, Karl A Beykirch, Betty J Mohler, Heinrich H Bülthoff

“…Potential reasons for these observations are discussed with regard to earlier findings and integrated within a functional model.…”
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Effects of Dioscorea oppositifolia L. on growth performance, biochemical indicators, immunity, and intestinal health of weaned piglets by Xiang-Yi Pan, Xiang-Yi Pan, Xiang-Yi Pan, Zheng-Ying Qiu, Zheng-Ying Qiu, Zheng-Ying Qiu, Chen Liu, Chen Liu, Chen Liu, Chuan Wang, Xiaowu Wang, Li-Na Huang, Si-Fan Li, Si-Fan Li, Si-Fan Li, Xiong-Wei Shi, Xiong-Wei Shi, Xiong-Wei Shi, Shao-Guang Ge, Shao-Guang Ge, Shao-Guang Ge, Rui-Hua Xin, Rui-Hua Xin, Rui-Hua Xin

“…Furthermore, supplementation with YAM can increase the villus height (VH), the ratio of villus height to crypt depth (V/C), and the expression of Tight junctions (TJs), and also has a positive regulatory effect on the intestinal flora.DiscussionIn summary, YAM alleviates weaning stress syndrome in piglets by promoting growth performance, improving immune function and disease resistance, improving intestinal morphology and mucosal immunity, and regulating the intestinal microbial composition of piglets. …”
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High-Fat Diet Aggravates the Intestinal Barrier Injury via TLR4-RIP3 Pathway in a Rat Model of Severe Acute Pancreatitis by Ying-ru Su, Yu-pu Hong, Fang-chao Mei, Chen-yang Wang, Man Li, Yu Zhou, Kai-liang Zhao, Jia Yu, Wei-xing Wang

“…Analyses of serum amylase, lipase, cholesterol, triglyceride, IL-1β, IL-6, DAO, and serum endotoxin as well as tight junction protein expression including zonula occluden-1 and occludin indicated that high-fat diet aggravated SAP-induced intestinal barrier injury via increasing inflammatory response. …”
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Network Pharmacology and In Vivo Evaluation of Lycium barbarum Polysaccharide in Preventing Perfluorooctanoic Acid-Induced Damage in Broilers by Nana Gao, Wenmei Yao, Yang Li, Xu Liu, Heping Bai, Xiaodan Wang

“…Protein-protein interaction analysis, GO functional annotation, and KEGG pathway enrichment analysis were performed. …”
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Neisseria meningitidis regulates P-glycoprotein transporter activity in brain endothelial cells via sphingosine 1–phosphate receptor 1 by Fatemeh Nosratabadi, Leo M. Endres, Fabian Schumacher, Heike Claus, Burkhard Kleuser, Brandon J. Kim, Alexandra Schubert-Unkmeir

“…Abstract Background The brain endothelial cells (BECs) are essential for protecting the central nervous system (CNS) from xenobiotics and pathogens, including Neisseria meningitidis, while maintaining CNS homeostasis through tight junction (TJ) proteins and specialized transporters. …”
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Palmitoleic acid on top of HFD ameliorates insulin resistance independent of diacylglycerols and alters gut microbiota in C57BL/6J mice by Qijian Liang, Yan Zheng, Fanli Meng, Xiaofan Jiang, Qingcai Zhen, Zhongting Lu, Shixiu Zhang, Lei Du, Hao Wu, Xin Guo

“…In colon, palmitoleic acid increased intestinal tight junction integrity and reduced inflammation. …”
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Gut microbiota modulation by Traditional Chinese Medicine: a translational strategy for metabolic dysfunction-associated steatotic liver disease by Ting Zhou, Ting Zhou, Ziwen Jin, Ziwen Jin, Rilei Jiang, Weiwei Li

“…Growing evidence highlights gut microbiota dysbiosis as a pivotal contributor to MASLD pathogenesis, characterized by disrupted intestinal barrier function, endotoxin translocation, and dysregulated bile acid (BA) and short-chain fatty acid (SCFA) metabolism. …”
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Oligochitosan Mitigates <i>Vibrio harveyi</i> Infection in Hybrid Groupers (<i>Epinephelus lanceolatus</i> ♂ × <i>Epinephelus fuscoguttatus</i> ♀) by Modulating Immune Responses an... by Fei Shi, Lixin Ma, Zhilong Chen, Hao Zhao, Cuiyun Zou, Li Lin, Zhendong Qin

“…These results demonstrate the detrimental effects of <i>V. harveyi</i> infection on the growth and immune function of hybrid groupers and the potential of oligochitosan to attenuate these effects.…”
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Mitochondrial dysfunction mediated by ER-calcium dysregulation in neurons derived from Alzheimer’s disease patients by Sarah Mustaly-Kalimi, Wacey Gallegos, Daniel Steinbrenner, Smriti Gupta, Aiden J. Houcek, David A. Bennett, Robert A. Marr, Daniel A. Peterson, Israel Sekler, Grace E. Stutzmann

“…Abstract Tight regulation of mitochondrial Ca2+ is essential for neuronal bioenergetics and cellular metabolism. …”
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How (Ultra‐)Rare Gene Variants Improve Our Understanding of More Common Autoimmune and Inflammatory Diseases by Alexandre Belot, Maud Tusseau, Jade Cognard, Sophie Georgin‐Lavialle, Guilaine Boursier, Christian M. Hedrich

“…Insights gained from studying rare genetic variants enhance our understanding of immune function in health and disease, paving the way for targeted therapies and personalized medicine.…”
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Significance of host antimicrobial peptides in the pathogenesis and treatment of acne vulgaris by Agata Lesiak, Paulina Paprocka, Urszula Wnorowska, Angelika Mańkowska, Grzegorz Król, Katarzyna Głuszek, Ewelina Piktel, Jakub Spałek, Jakub Spałek, Sławomir Okła, Sławomir Okła, Krzysztof Fiedoruk, Bonita Durnaś, Bonita Durnaś, Robert Bucki

“…In particular, their role in improving the tight junctions (TJs) skin barrier by activating the fundamental cellular proteins, such as PI3K, GSK-3, aPKC, and Rac1, is discussed. …”
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Effects of Enteromorpha prolifera polysaccharide on intestinal health of spotted sea bass Lateolabrax maculatus by Zhongying Long, Longhui Liu, Huihui Qin, Sishun Zhou, Lumin Kong, Jianrong Ma, Hao Lin, Zhangfan Huang, Yi Lin, Zhongbao Li

“…Transcriptome results suggest that EPP may improve intestinal tissue morphology and intestinal barrier function by up-regulating tight junction protein 1 (TJP1) and zona occludens 1 (ZO-1) genes, thereby improving intestinal health. …”
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