Isoform‐resolved correlation analysis between mRNA abundance regulation and protein level degradation by Barbora Salovska, Hongwen Zhu, Tejas Gandhi, Max Frank, Wenxue Li, George Rosenberger, Chongde Wu, Pierre‐Luc Germain, Hu Zhou, Zdenek Hodny, Lukas Reiter, Yansheng Liu

“…Our findings support the tight association between transcriptome variability and proteostasis and provide a methodological foundation for studying functional protein degradation.…”
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A synbiotic combination of mixed probiotics and oligofructose restores intestinal microbiota disturbance in DSS-induced colitis in mice by Weiwei Ma, Lian Lian, Lidong Guo, Yanan Wu, Lili Huang

“…In addition, through metagenomic data analysis, mixed probiotics combined with oligofructose can enhance the diversity and richness of gut microbiota, increase the abundance of beneficial bacteria Bifidobacterium and Lactobacillus, promote the production of SCFAs, and enhance intestinal barrier function. It is worth noting that the therapeutic effect of synbiotics depends on the dose of mixed probiotics. …”
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User velocity estimation in HetNets utilizing vertical and horizontal handover counts via maximum likelihood estimation by Ravi Tiwari, Sourabh Paul, Manoj Kumar Singh, Amit Kumar Rahul, K. Akilan

“…We utilized mathematical modeling to estimate that the probability mass function (PMF) of the handover counts in the HetNets scenario follows a Rayleigh distribution. …”
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Effects of Glucose Concentration on Propofol Cardioprotection against Myocardial Ischemia Reperfusion Injury in Isolated Rat Hearts by Xinhua Yao, Yalan Li, Mingzhe Tao, Shuang Wang, Liangqing Zhang, Jiefu Lin, Zhengyuan Xia, Hui-min Liu

“…Similarly, the beneficial effect of tight glycemic control during cardiac surgery in patients has recently been questioned. …”
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Tongxinluo attenuates reperfusion injury in diabetic hearts by angiopoietin-like 4-mediated protection of endothelial barrier integrity via PPAR-α pathway. by Kang Qi, Xiangdong Li, Yongjian Geng, Hehe Cui, Chen Jin, Peihe Wang, Yue Li, Yuejin Yang

“…<h4>Objective</h4>Endothelial barrier function in the onset and Tongxinluo (TXL) protection of myocardial ischemia/reperfusion (I/R) injury, and TXL can induce the secretion of Angiopoietin-like 4 (Angptl4) in human cardiac microvascular endothelial cells during hypoxia/reoxygenation. …”
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The Role of E-Cadherin in the Assessment of Esophageal Mucosal Damage in Patients with Gastroesophageal Reflux Disease Associated with Obstructive Sleep Apnea/Hypopnea Syndrome by Y. Ya. Shaukovich

“…OSAHS negatively affects the state of histoarchitecture of the esophageal mucosa of GERD patients, as evidenced by an increase in N-terminal E-cadherin in the blood plasma and may indicate a loss of E-cadherin in the esophageal mucosa with the development of an impaired function of tight junctions.…”
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Structural Defects Associated with Craniectomy Induce Neuroinflammation and Blood–Brain Barrier Permeability by Aria W. Tarudji, Brandon Z. McDonald, Evan Curtis, Connor Gee, Forrest M. Kievit

“…Last, craniectomy contributed to the altered expression of several tight junction proteins, including occludin and claudin-1/5, suggesting the blood–brain barrier was perturbed. …”
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Microbiota Composition and the Integration of Exogenous and Endogenous Signals in Reactive Nasal Inflammation by Francesco Antonio Salzano, Luigi Marino, Giovanni Salzano, Riccardo Maria Botta, Giovanni Cascone, Umberto D’Agostino Fiorenza, Carmine Selleri, Vincenzo Casolaro

“…It is now clear that the local microbiota is a major player in the development of the mucosa-associated lymphoid tissue and in the regulation of such adaptive responses as IgA production and the function of effector and regulatory T cells. Microbial components also play a major role in the regulation of epithelial barrier functions, including mucus production and the control of paracellular transport across tight junctions. …”
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CRABP1 Signalosomes in Non-Canonical Actions of Retinoic Acid—Maintaining Health and Preventing Thyroid Dysfunction in Aging by Jennifer Nhieu, Fatimah Najjar, Li-Na Wei

“…The CRABP1 sequence is highly conserved, likely due to its functional constraint in forming various signalosomes; its tight regulation ensures proper expression of CRABP1 required for the forming of various signalosomes critical to the health and functions of multiple cell types/organ systems. …”
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Edaravone Dexborneol Downregulates Neutrophil Extracellular Trap Expression and Ameliorates Blood-Brain Barrier Permeability in Acute Ischemic Stroke by Yuanxiang Huang, Xiangjian Zhang, Cong Zhang, Wenting Xu, Wenshuo Li, Zixin Feng, Xianglan Zhang, Keke Zhao

“…Eda.B significantly improved neurological function and cerebral blood flow but reduced infarct volume after experimental stroke. …”
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Effects of dietary supplementation with Bacillus subtilis and bacteriophage on growth performance, intestinal morphology and microbiota structure in 0–90 d MaGang geese by Chenyu Zhu, Yongquan Luo, Kunjie Xu, Yong Li, Yuanhao Han, Zhiyuan Liu, Xiujin Li, Danning Xu, Yunbo Tian, Yunmao Huang, Zhongping Wu, Xumeng Zhang

“…Intestinal morphology improvements included increased villus height and optimized villusto-crypt ratios, accompanied by up-regulated expression of tight junction genes (Zo-1 and Ocln). Cecal microbiota analysis revealed enhanced alpha diversity and a shift toward Bacteroides-dominant communities, with concurrent suppression of Proteobacteria. …”
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Toll-Like Receptor-Mediated Cardiac Injury during Experimental Sepsis by Ina Lackner, Birte Weber, Shinjini Chakraborty, Sonja Braumüller, Markus Huber-Lang, Florian Gebhard, Miriam Kalbitz

“…Sepsis affected cardiac structure and gap junction proteins in mice, potentially contributing to compromised cardiac function.…”
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Altered Cytokine Expression and Barrier Properties after In Vitro Infection of Porcine Epithelial Cells with Enterotoxigenic Escherichia coli and Probiotic Enterococcus faecium by Martina Kern, Dorothee Günzel, Jörg R. Aschenbach, Karsten Tedin, Angelika Bondzio, Ulrike Lodemann

“…Cells were incubated with E. faecium, ETEC, or both, and the effects on barrier function and structure and intra- and intercellular signaling were determined. …”
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Water-soluble garlic polysaccharide (WSGP) improves ulcerative colitis by modulating the intestinal barrier and intestinal flora metabolites by Xin Shao, JiaLong Li, Qi Shao, Rong Qu, Xin Ouyang, Yong Wang, ChunBo Chen

“…This study demonstrates that WSGP supplementation attenuates UC mice by suppressing the NF-κB/STAT3 signaling pathway, enhancing mucosal barrier function, reducing pro-inflammatory cytokines, and modulating gut microbial metabolites.…”
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Design and Fabrication of a Car Sports Rims. by Nsimbe Laban

“…The casted rim was then submerged in a pool of water, no bubbles were observed hence the rim was found to be air tight. A permanent mould is however recommended for this study so as to give a better surface finish and better dimensional tolerance. …”
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Whole Genome Analysis of <i>Pediococcus acidilactici</i> XJ-24 and Its Role in Preventing <i>Listeria monocytogenes</i> ATCC^® 19115^TM Infection in C57BL/6 Mic... by Weizhong Hu, Shuxin Zhou, Amel Ibrahim, Guannan Li, Sameh Awad, José Ramos-Vivas, Jianquan Kan, Muying Du

“…Correlation analysis highlighted a positive association between <i>Lachnospiraceae</i> and tight junction proteins. <b>Conclusions:</b> These findings demonstrate the potential of XJ-24 as a functional probiotic for preventing LM infection and provide a basis for further clinical exploration.…”
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“Loss of polarity of basal cells” – The term revisited in the light of genomics by Debasish Pramanick, Richa Singh, Bidyut Roy, Anjana Mazumdar, Sandip Ghose

“…The epithelial cells exhibit apicobasal polarity which is maintained by Crumbs complex located at apical region of tight junction, ‘PAR’ complex at sub-apical region of tight junction and Scribble complex at adherens junction. …”
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Early weaning-induced intestinal barrier dysfunction associates with Th17/Treg imbalance in squabs by Qianqian Xu, Zhiying Luo, Tianliang Ling, Wenyan Zhao, Xinyang Dong

“…The mRNA expression of ileal tight junction proteins of weaned squabs was significantly downregulated at multiple time points from 1 to 21 days after weaning. …”
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CHIVID: A Rapid Deployment of Community and Home Isolation During COVID-19 Pandemics by Parpada Piamjinda, Chiraphat Boonnag, Piyalitt Ittichaiwong, Seandee Rattanasonrerk, Kanyakorn Veerakanjana, Khanita Duangchaemkarn, Warissara Limpornchitwilai, Kamonwan Thanontip, Napasara Asawalertsak, Thitikorn Kaewlee, Theerawit Wilaiprasitporn

“…Background: CHIVID is a telemedicine solution developed under tight time constraints that assists Thai healthcare practitioners in monitoring non-severe COVID-19 patients in isolation programs during crises. …”
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Exploring the beneficial effects of GHK-Cu on an experimental model of colitis and the underlying mechanisms by Shuzhen Mao, Jiahui Huang, Junyan Li, Fang Sun, Qilian Zhang, Qing Cheng, Wei Zeng, Dongya Lei, Shiyan Wang, Jing Yao

“…IntroductionUlcerative colitis (UC) is a chronic inflammatory bowel disease (IBD) characterized by mucosal damage and impaired epithelial barrier function. While glycyl-l-histidyl-l-lysine-copper (GHK-Cu) exhibits known anti-inflammatory properties, its therapeutic mechanisms in UC remain undefined. …”
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