PcG-mediated higher-order chromatin structures modulate replication programs at the Drosophila BX-C. by Federica Lo Sardo, Chiara Lanzuolo, Federico Comoglio, Marco De Bardi, Renato Paro, Valerio Orlando

“…Polycomb group proteins (PcG) exert conserved epigenetic functions that convey maintenance of repressed transcriptional states, via post-translational histone modifications and high order structure formation. …”
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Holographic reconstruction of black hole spacetime: machine learning and entanglement entropy by Byoungjoon Ahn, Hyun-Sik Jeong, Keun-Young Kim, Kwan Yun

“…We find that the metrics for a tight-binding chain and the Gubser-Rocha model are similar. …”
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Paradigm of tunable clustering using Binarization of Consensus Partition Matrices (Bi-CoPaM) for gene discovery. by Basel Abu-Jamous, Rui Fa, David J Roberts, Asoke K Nandi

“…Also, these algorithms cannot generate tight clusters that focus on their cores or wide clusters that overlap and contain all possibly relevant genes. …”
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Theoretical Prediction of the Impact of Phosphorus Doping on the Elastic Constants of Silicon by Azadeh Jafari, Behraad Bahreyni

“…The Goodwin–Skinner–Pettifor functional form was applied to estimate dopant-induced stress potentials and their effect on lattice stiffness. …”
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Breaking Barriers: The Detrimental Effects of Combined Ragweed and House Dust Mite Allergen Extract Exposure on the Bronchial Epithelium by Răzvan-Ionuț Zimbru, Manuela Grijincu, Gabriela Tănasie, Elena-Larisa Zimbru, Florina-Maria Bojin, Roxana-Maria Buzan, Tudor-Paul Tamaș, Monica-Daniela Cotarcă, Octavia Oana Harich, Raul Pătrașcu, Laura Haidar, Elena Ciurariu, Karina Cristina Marin, Virgil Păunescu, Carmen Panaitescu

“…This study investigated the impact of single- versus combined-allergen exposure on the barrier function of normal human bronchial epithelial (NHBE) cells cultured at the air–liquid interface (ALI). (2) Methods: NHBE cells were exposed to RW pollen extract (200 µg/mL), HDM extract (200 µg/mL) and their combination at varying concentrations (200 µg/mL, 100 µg/mL, 50 µg/mL, 25 µg/mL). …”
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Effect of dietary supplementation with aspirin eugenol ester on performance and ileum health in broilers under high stocking density stress conditions by Penghui Ma, Penghui Ma, Yi Zhang, Yi Zhang, Dongying Bai, Dongying Bai, Wenrui Zhen, Wenrui Zhen, Caifang Guo, Koichi Ito, Bingkun Zhang, Yanbo Ma, Yanbo Ma, Yanbo Ma

“…This study investigated the influence of dietary aspirin eugenol ester (AEE) on growth performance, ileum antioxidant capacity, intestinal barrier function and ileum microbiota of broilers subjected to high stocking density stress (HDS). …”
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The green tea component (−)-epigallocatechin-3-gallate protects against cytokine-induced epithelial barrier damage in intestinal epithelial cells by Rita Rosenthal, Anne Waesch, Kopano Valerie Masete, Alain S. Massarani, Jörg-Dieter Schulzke, Nina A. Hering

“…Furthermore, alterations in tight junction protein expression and localization contributed to barrier protection. …”
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Investigation of the tissue displacement through textile pressure on soft avatar in Browzwear’s VStitcher software by Elena Alida Brake, Yordan Kyosev, Katerina Rose

“…Likewise, they are also utilized in the garment industry in order to achieve a realistic testing of the fit and functionality of tight-fitting clothing. Therefore it is important that avatars in CAD programs for clothing conform to the mechanical properties of human soft tissue. …”
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Retroffiting and Repairing Cooling Tower Structure Within A Tide Deadline by Benny Dwika Leonanda

“…The project was completed within a tight timeline of 10 days to ensure long-term reliability of operations at the plant.…”
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Stochastic Block-Coordinate Gradient Projection Algorithms for Submodular Maximization by Zhigang Li, Mingchuan Zhang, Junlong Zhu, Ruijuan Zheng, Qikun Zhang, Qingtao Wu

“…Moreover, we show that the proposed algorithm achieves the tight (pmin/2F⁎-ϵ) approximation guarantee after O(1/ϵ2) iterations for DR-submodular functions by choosing appropriate step sizes. …”
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Tunnels under geometries (or instantons know their algebras) by Dmitry Galakhov, Alexei Morozov

“…Abstract In the tight binding model with multiple degenerate vacua we might treat wave function overlaps as instanton tunnelings between different wells (vacua). …”
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Systemic Associations with Residual Subretinal Fluid after Ranibizumab in Diabetic Macular Edema by Meng-Ju Tsai, Yi-Ting Hsieh, Elizabeth P. Shen, Yi-Jie Peng

“…Overall, lower eGFR and lower HbA1c values, contrary to popular belief, predicted the presence of residual SRF following intravitreal injections (p=0.016 and p<0.001, resp.). Conclusions. Tight sugar control and poorer baseline kidney function may slow the resorption of SRF after anti-VEGF injections in patients with DME in the short term.…”
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Insomnia and microbiota: clinical and pathophysiological relationships by V. A. Akhmedov, T. N. Fedorova, A. S. Isaeva

“…Chronic insomnia, in turn, can disrupt microbial circadian rhythms, thereby affecting the composition and function of the intestinal microbiota. Jet lag syndrome causes a significant increase in body weight and blood glucose levels due to its effect on the composition of the human intestinal microbiome. …”
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Defective glutamate and K+ clearance by cortical astrocytes in familial hemiplegic migraine type 2 by Clizia Capuani, Marcello Melone, Angelita Tottene, Luca Bragina, Giovanna Crivellaro, Mirko Santello, Giorgio Casari, Fiorenzo Conti, Daniela Pietrobon

“…A subtype of migraine with aura (familial hemiplegic migraine type 2: FHM2) is caused by loss‐of‐function mutations in α2 Na+,K+ ATPase (α2 NKA), an isoform almost exclusively expressed in astrocytes in adult brain. …”
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Interstitial Lung Disease in Rheumatoid Arthritis in the Era of Biologics by A. Picchianti Diamanti, V. Germano, E. Bizzi, B. Laganà, A. Migliore

“…Some reports suggest a causative role for TNFα inhibitors in RA-ILD development/worsening, anyway, no definitive statement can be drawn thus data are incomplete and affected by several variables. A tight control (pulmonary function tests and/or HRCT) is mandatory in patients with preexisting ILD, but it should be also performed in those presenting risk factors for ILD and mild respiratory symptoms. …”
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Crosstalk between inovirus core gene and accessory toxin-antitoxin system mediates polylysogeny by Jiayu Gu, Yunxue Guo, Juehua Weng, Shituan Lin, Yabo Liu, Xiaoxue Wang

“…Our findings provide valuable insights into the significance of the tight regulation between phage core genes and accessory genes in establishing a mutualistic interaction between co-resident prophages.…”
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Development and Clinical Application of High-Magnification Electronic Endoscope by Fan WANG, Jiansong XIA, Hui YANG, Guofei YAN, Jiaying HE, Liqiang WANG

“…Additionally, the tip and operation parts of the system incorporate modular gas-tight sealing and multiple layers of protective structure. …”
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Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology by Brian Cox, Max Kotlyar, Andreas I Evangelou, Vladimir Ignatchenko, Alex Ignatchenko, Kathie Whiteley, Igor Jurisica, S Lee Adamson, Janet Rossant, Thomas Kislinger

“…Several of these phenotype‐associated proteins form a tight protein–protein interaction network involving 15 known and 34 novel candidate proteins also likely important in placental structure and/or function. …”
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RNA interference and single particle tracking analysis of hepatitis C virus endocytosis. by Kelly E Coller, Kristi L Berger, Nicholas S Heaton, Jacob D Cooper, Rosa Yoon, Glenn Randall

“…Entering HCV particles are associated with the receptor molecules CD81 and the tight junction protein, claudin-1; however, HCV-claudin-1 interactions were not restricted to Huh-7.5 cell-cell junctions. …”
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Mobile Robot Path Planning Considering Obstacle Gap Features by Hongwei Wang, Li He, Shuai Zhang, Ruoyang Bai, Yunhang Wang

“…Specifically, this method addresses the issues of low search efficiency, excessive redundant points, and poor path quality in the traditional A* algorithm for global path planning by extracting gap grids in the global grid map and incorporating their influence into the heuristic function, thereby guiding the search more effectively. …”
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