ZeXieYin formula alleviates atherosclerosis by regulating SBAs levels through the FXR/FGF15 pathway and restoring intestinal barrier integrity by Shihan Zhou, Shangbo Hua, Xinyi Chen, Meiling Ni, Jing Liu, Yanqing Wang, Wanning Wu, Anni Ding, Zizhen Qin, Xinyu Yang, Xiaowei Chen, Boran Zhu, Haoxin Wu

“…Additionally, we identified tight-junction proteins in the ileal tissues through IF. …”
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The 100 pc White Dwarf Sample in the SDSS Footprint. II. A New Look at the Spectral Evolution of White Dwarfs by Mukremin Kilic, Pierre Bergeron, Simon Blouin, Adam Moss, Warren R. Brown, Antoine Bédard, Gracyn Jewett, Marcel A. Agüeros

“…Finally, we detect a relatively tight sequence of low-mass DQ white dwarfs in color–magnitude diagrams for the first time. …”
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Acute stress-induced alterations in short-chain fatty acids: Implications for the intestinal and blood brain barriers by Cristina Rosell-Cardona, Sarah-Jane Leigh, Emily Knox, Emanuela Tirelli, Joshua M. Lyte, Michael S. Goodson, Nancy Kelley-Loughnane, Maria R. Aburto, John F. Cryan, Gerard Clarke

“…This functional protection was associated with altered tight-junction abundance and morphology. …”
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Fermented Dairy Products as Precision Modulators of Gut Microbiota and Host Health: Mechanistic Insights, Clinical Evidence, and Future Directions by Yuan Gao, Yanyan Liu, Tingting Ma, Qimeng Liang, Junqi Sun, Xiaomeng Wu, Yinglong Song, Hui Nie, Jun Huang, Guangqing Mu

“…This review synthesizes mechanistic insights demonstrating how live starter cultures and their fermentation-derived metabolites (short-chain fatty acids, bioactive peptides, and exopolysaccharides) act synergistically to enhance microbial diversity, reinforce epithelial barrier integrity via upregulation of tight-junction proteins, and modulate immune signaling. …”
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From behavioral synchrony to language and beyond by Katherine Eulau, Kathy Hirsh-Pasek, Kathy Hirsh-Pasek

“…We address the known neural correlates of these processes with an emphasis on work that examines the tight temporal contingency between communicative partners during these rich social interactions, with a focus on EEG and fNIRS and brief survey of MRI and MEG.…”
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Pathogenicity of Arcobacter cryaerophilus in two human intestinal cell lines by Antonia Bachus, Sarah Beyer, Roland Bücker, Soroush Sharbati, Thomas Alter, Greta Gölz

“…The ability to disrupt the epithelial barrier function of T84 cell monolayers was shown for two strains by measurement of transepithelial electrical resistance. …”
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Synaptotagmin-7 outperforms synaptotagmin-1 to promote the formation of large, stable fusion pores via robust membrane penetration by Kevin C. Courtney, Taraknath Mandal, Nikunj Mehta, Lanxi Wu, Yueqi Li, Debasis Das, Qiang Cui, Edwin R. Chapman

“…We discover that synaptotagmin-1—membrane interactions are greatly influenced by membrane order; tight packing of phosphatidylserine inhibits binding due to impaired membrane penetration. …”
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The Onset of Enhanced Intestinal Permeability and Food Sensitivity Triggered by Medication Used in Dental Procedures: A Case Report by Aristo Vojdani, Jama Lambert

“…Four weeks after the final dental procedure, she was assessed serologically for mucosal immune function, salivary, and blood-gluten reactivity, intestinal permeability, and other food sensitivities. …”
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Stromal Claudin14-heterozygosity, but not deletion, increases tumour blood leakage without affecting tumour growth. by Marianne Baker, Louise E Reynolds, Stephen D Robinson, Delphine M Lees, Maddy Parsons, George Elia, Kairbaan Hodivala-Dilke

“…Here we have investigated the role of a tight junction molecule, Claudin 14, in tumour blood vessel leakage, angiogenesis and tumour growth. …”
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Spin transport properties in a topological insulator sandwiched between two-dimensional magnetic layers by Nezhat Pournaghavi, Banasree Sadhukhan, Anna Delin

“…We have considered a heterostructure consisting of a TI, namely Bi $$_2$$ Se $$_3$$ , sandwiched between two two-dimensional ferromagnetic monolayers of CrI $$_3$$ , to study how its topological and transport properties change due to the proximity effect. Combining DFT and tight-binding calculations, along with non-equilibrium Green’s function formalism, we show that a well-defined exchange gap appears in the band structure in which spin-polarised edge states flow. …”
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Metformin improves intestinal ischemia-reperfusion injury by reducing the formation of mitochondrial associated endoplasmic reticulum membranes (MAMs) and inhibiting ferroptosis in... by Xu Zhao, Likun Yan, Lifei Tian, Xiaolong Zhang, Ruiting Liu, Zeyu Li

“…ResultsThe results from HE staining in the in vivo model, along with IF staining of tight junction proteins in the in vitro model, clearly demonstrated that metformin effectively mitigated the damage to the intestinal barrier following I/R injury. …”
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Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy. by Sophie Moncrieff, Matthieu Moncan, Flavia Scialpi, Mark Ditzel

“…These findings are important as tight temporal/spatial regulation of hh ligand expression underlies its important roles in animal development and tissue homeostasis. …”
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SoK: Security of the Ascon Modes by Charlotte Lefevre, Bart Mennink

“… The Ascon authenticated encryption scheme and hash function of Dobraunig et al. (Journal of Cryptology 2021) were recently selected as winner of the NIST lightweight cryptography competition. …”
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A lightweight framework to secure IoT devices with limited resources in cloud environments by Vivek Kumar Pandey, Dinesh Sahu, Shiv Prakash, Rajkumar Singh Rathore, Pratibha Dixit, Iryna Hunko

“…Abstract Billions of IoT devices increasingly function as gateways to cloud infrastructures, making them an inevitable target of cyber threats because of the limited resources and low processing capabilities of IoT devices. …”
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Research Progress in Lactoferrin’s Role in Alleviating Intestinal Barrier Dysfunction by LI Yi, REN Xinxin, WANG Qin, HE Xiaoyun

“…Lactoferrin, a glycoprotein abundant in mammalian milk, exhibits a range of biological functions such as antioxidant, anti-inflammatory and antibacterial functions. …”
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Inhibition of platelet activation alleviates diabetes-associated cognitive dysfunction via attenuating blood-brain barrier injury by Fuxing Xu, Juan Hu, Xuying Li, Lan Yang, Shiqiu Jiang, Tao Jiang, Bo Cheng, Hailiang Du, Ruiduo Wang, Yingying Deng, Wei Gao, Yansong Li, Yaomin Zhu

“…In vitro, CD40L increased HIF1α, diminished tight junction proteins and dysregulated Aβ transporters in b.End3 cells, which could be restored by CD40 siRNA and HIF1α siRNA. …”
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Evaluation of the efficacy of icariin against heat stress-induced spermatogenic dysfunction in the testes of dogs by Baoan Li, Liuwei Xie, Mingqiang Song, Xiumin Zhang, Chuanguo Yan, Wanpeng Gao, Wenxing Wang, Yang Yang

“…IntroductionThis study examines the detrimental effects of high-temperature environments on canine testicular function and reproductive health, and investigates the potential of Epimedii Folium, particularly its active component icariin, in alleviating these effects and improving testicular function.MethodsA completely randomized single-factor design was employed, involving 24 adult male Beagle dogs (9.82 ± 0.73 kg) assigned randomly to four treatment groups, with six dogs in each group. …”
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Proteome profile differences among human, monkey, and mouse brain microvessels and cultured brain microvascular endothelial cells by Haruka Kumabe, Takeshi Masuda, Shingo Ito, Tomomi Furihata, Akiko Toda, Masayuki Mogi, Norie Araki, Sumio Ohtsuki

“…Abstract Background The blood-brain barrier (BBB) expresses transporters, receptors, and tight junction proteins that regulate the exchange of substances between the blood and brain. …”
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The interventional role and mechanism of total flavonoids in lychee seeds on rats with liver fibrosis by Xie Jiacheng, Huang Guochu, Li Minhang, Cui Yinhang, Zhang Yu, Zhang Xia, Yang Jingyun, Tang Meiwen, Luo Weisheng, Ma Xiaocong

“…Immunohistochemistry detected the expression of tight junction proteins ZO-1, occludin, claudin 1, and claudin 4 related to the intestinal barrier. …”
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Excretory/secretory products from Hymenolepis nana adult worms alleviate ulcerative colitis in mice via tuft/IL-13 signaling pathway by Rong Mou, Xuanyin Cui, Hongyan Wang, Zhenfen Zhang, Yi Cheng, Wenlan Wu, Jinfu Li, Ke Zhang

“…The protective mechanism of ESPs might be related to the activation of the tuft/IL-13 signaling pathway, regulating intestinal barrier function and promoting the regeneration of intestinal stem cells. …”
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