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401
Robust object counting through distribution uncertainty matching and optimal transport
Published 2025-08-01“…DUMLO formulates the loss function as a coupling between two optimal transport problems, which involves an unknown density map defined over the augmented points. …”
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402
Myeloperoxidase-derived oxidants induce blood-brain barrier dysfunction in vitro and in vivo.
Published 2013-01-01“…BMVEC treatment with the MPO-H2O2-Cl(-) system or activated neutrophils resulted in the formation of plasmalogen-derived chlorinated fatty aldehydes. 2-chlorohexadecanal (2-ClHDA) severely compromised BMVEC barrier function and induced morphological alterations in tight and adherens junctions. …”
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403
MicroRNA-155 modulates methotrexate-induced spatial memory impairment by disruption of the blood-brain barrier integrity
Published 2025-03-01“…Tight junction proteins expression were also examined. …”
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404
Supplemental Bacillus subtilis PB6 Improves Growth Performance and Gut Health in Broilers Challenged with Clostridium perfringens
Published 2021-01-01“…The present research examined the effect of Bacillus subtilis PB6 (B. subtilis PB6) on growth performance, mRNA expression of intestinal cytokines and tight junctions, and gut flora composition in broilers challenged with CP. …”
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405
RNF213 regulates blood‒brain barrier integrity by targeting TRAF3 for type I interferon activation during A. baumannii infection.
Published 2025-07-01“…RNF213 is the first identified susceptibility gene for moyamoya disease, and the encoded protein was recently recognized as a key antimicrobial protein. However, the function of RNF213 in host defense against brain infection remains unclear. …”
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406
Reduced gap junction coupling amplifies the effects of cardiomyocyte variability and destabilizes the heartbeat
Published 2025-07-01“…However, such effects may be suppressed by tight electrical coupling of cells in the healthy heart, but not during pathological conditions where gap junction function is impaired. …”
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407
The epithelial cell adhesion molecule EpCAM is required for epithelial morphogenesis and integrity during zebrafish epiboly and skin development.
Published 2009-07-01“…However, the in vivo function of EpCAM still remains elusive due to the lack of genetic loss-of-function studies. …”
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408
Genetic analysis of pathways regulated by the von Hippel-Lindau tumor suppressor in Caenorhabditis elegans.
Published 2004-10-01“…The von Hippel-Lindau (VHL) tumor suppressor functions as a ubiquitin ligase that mediates proteolytic inactivation of hydroxylated alpha subunits of hypoxia-inducible factor (HIF). …”
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409
Older people’s day centres’ preventive work: views of day centre providers and their stakeholders
Published 2025-12-01“…Methods After obtaining ethical approval, we conducted qualitative interviews with 10-day centre stakeholders and 9 professional stakeholders, exploring their perceptions of day centres’ preventive function. Participants’ job roles provide context, while individual characteristics are anonymized. …”
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410
Bounds on the Twin-Width of Product Graphs
Published 2023-06-01“…Given two graphs $G$ and $H$ and a graph product $\star$, we address the question: is the twin-width of $G\star H$ bounded by a function of the twin-widths of $G$ and $H$ and their maximum degrees? …”
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411
Nonreciprocal coupling triggers pinning-depinning transitions of wavefronts in bistable systems chains
Published 2025-08-01“…Close to the bifurcation, the front velocity is characterized by a square root law as a function of the bifurcation parameter. We can adequately account for the experimental observations using a tight-binding theoretical model.…”
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412
DRP1, fission and apoptosis
Published 2025-04-01“…As a pivotal molecule in the process of mitochondrial fission, the function of DRP1 is regulated at multiple levels, including transcription, post-translational modifications. …”
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413
Alleviating the Effect of Branched-Chain Fatty Acids on the Lipopolysaccharide-Induced Inflammatory Response in Calf Small Intestinal Epithelial Cells
Published 2025-05-01“…In summary, BCFA supplementation mitigated oxidative stress and enhanced mitochondrial function. BCFA inhibited <i>TLR4/NF-κB</i> signaling pathway overactivation, regulated inflammatory cytokine gene expression, reduced cellular apoptosis, preserved tight junction integrity, and supported barrier function.…”
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414
Budesonide promotes airway epithelial barrier integrity following double-stranded RNA challenge.
Published 2021-01-01“…Respiratory viruses are responsible for a large fraction of asthma exacerbations, and are particularly potent at disrupting epithelial barrier function through pattern recognition receptor engagement leading to tight junction dysfunction. …”
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415
Oxyberberine alleviates lipopolysaccharide-induced intestinal barrier disruption and inflammation in human colonic Caco-2 cells in vitro
Published 2025-01-01“…Moreover, OBB ameliorated the LPS-induced decrease in the distribution and expression of several tight junction markers, including ZO-1, occludin, and E-cadherin. …”
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416
Blueberry Attenuates Liver Fibrosis, Protects Intestinal Epithelial Barrier, and Maintains Gut Microbiota Homeostasis
Published 2019-01-01“…CCl4 impaired the intestinal epithelial barrier and decreased the expression of the tight junction protein. Blueberry restored the intestinal epithelial barrier and increased the expression of the tight junction protein. …”
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417
Bootstrapping the Quantum Hall Problem
Published 2025-07-01“…Here, we employ a bootstrap approach to study interacting electrons in the lowest Landau level by minimizing the energy as a function of the static structure factor subject to a set of constraints, bypassing the need to construct the full many-body wave function. …”
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418
Molecular Motors in Blood–Brain Barrier Maintenance by Astrocytes
Published 2025-03-01“…In particular, astrocytes are essential for BBB function, as they maintain BBB integrity through their end-feet, which form a physical and biochemical interface that enhances endothelial cell function and barrier selectivity. …”
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419
A New Method for Constructing Integral-Resistance Matrix for 5-Round AES
Published 2025-01-01“…Since it is well known that there is a 4-round integral distinguisher for AES, our result is tight for AES. As far as we know, this is the first proof for the integral-resistance property of 5-round AES.…”
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420
The Structural Stability of Enzymatic Proteins in the Gas Phase: A Comparison of Semiempirical Hamiltonians and the GFN-FF
Published 2025-05-01“…The employed levels of theory were semiempirical, density functional tight binding, and polarizable force-field techniques. …”
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