Integration and Application of Microlens Arrays Within Heads-Up Displays by Weicheng Yan, Xian Jin, Hongbae S. Park, Ashli Le Blanc, Hamid Abdollahi, Boris Stoeber, Jonathan F. Holzman

“…The proposed work targets a fundamental challenge in heads-up display technology—in that such displays must bring about tight imaging with a flat form factor to support integration within eyewear. …”
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Sphingosine-1-phosphate alleviates colitis by regulating macrophage polarization and PI3k-Akt signaling by Liang Hu, Zi Yang, Zi Yang, Ying Zhang, Conglin Du, Yang Yang, Yang Yang, Zhichao Chang, Xiangchun Li, Zhaochen Shan

“…IntroductionInflammatory bowel disease (IBD) is a complex disease that is characterized by tight junction loss and dysregulation of immune homeostasis. …”
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Gentiopicroside improves DSS-induced ulcerative colitis and secondary liver injury in mice by enhancing the intestinal barrier and regulating the gut microbiome by Liu Cao, Mengyuan Niu, Xiaoqing Tang, Yiting Wang, Xianjing Hu, Weibo Dai

“…Mice were evaluated for body weight, Disease Activity Index (DAI), colon length, histopathology, tight junction protein expression, gut microbiota composition, inflammatory cytokine levels, and liver function biomarkers. …”
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Energy landscape of a Kv channel revealed by temperature steps while perturbing its electromechanical coupling by Bernardo I. Pinto-Anwandter, Carlos A. Z. Bassetto, Ramon Latorre, Francisco Bezanilla

“…Our findings support a loose or tight conformation of the electromechanical coupling. …”
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Role of Autophagy Inducers and Inhibitors in Intestinal Barrier Injury Induced by Intestinal Ischemia–Reperfusion (I/R) by Yuejin Li, Peng Zhang, Jian Zhang, Weimin Bao, Jinyuan Li, Yan Wei, Jinchao Ni, Kunmei Gong

“…The autophagy inhibitor 3-MA and the autophagy inducer rapamycin (RAP) were used to change the level of autophagy, and then, the expressions of tight junction proteins and intestinal barrier function were detected. …”
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Family of attainable geometric quantum speed limits by Zi-yi Mai, Zheng Liu, Chang-shui Yu

“…We numerically compare the tightness of the three QSL times, which typically promises a tighter QSL time if optimizing the alternative function.…”
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Joint Entropy Error Bound of Two-Dimensional Direction-of-Arrival Estimation for L-Shaped Array by Xiaolong Kong, Daxuan Zhao, Nan Wang, Dazhuan Xu

“…The Cramér–Rao bound (CRB) can guarantee asymptotic tightness in the high-signal-to-noise ratio (SNR) region but cannot provide tight performance bounds for parameter estimators in low- and medium-SNR regions. …”
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Tad pili with adaptable tips mediate contact-dependent killing during bacterial predation by Julien Herrou, Laetitia My, Caroline L. Monteil, Marine Bergot, Rikesh Jain, Emmanuelle Martinez, Tâm Mignot

“…Remarkably, the activity of these Tips also depends on the T3SS*, revealing a tight functional connection between the Kil system and the T3SS*. …”
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Research on the construction of corneal endothelium transplantation with acellular amniotic membrane as a scaffold by Ya-Nan Chen, Rui-Qin Guo, Bo-Yu Liang, Hong-Qin Ke, Meng-Jie Dong, Ming-Fang He, Ji Yang, Hai Liu

“…The HAAM promoted cell viability and proliferation, as evidenced by positive expression of tight junction proteins and upregulation of key functional genes. …”
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Biochemical mapping reveals a conserved heme transport mechanism via CcmCD in System I bacterial cytochrome c biogenesis by Alicia N. Kreiman, Sarah E. Garner, Susan C. Carroll, Molly C. Sutherland

“…Heme can also be toxic to cells and thus requires tight regulation and specific trafficking pathways. …”
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Chronic Syndesmotic Instability Associated with a Complex Lesion of the Posterior Inferior Tibiofibular Ligament: Review, Case Report, and Surgical Report by Virginie Perez, Nermine Habib, Angela Seidel

“…The combination of osteotomy, TightRope® syndesmosis fixation, and InternalBrace™ PITFL repair provides a reliable option for managing complex PITFL injuries.…”
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The Rho-Rock-Myosin signaling axis determines cell-cell integrity of self-renewing pluripotent stem cells. by Nicole Harb, Trevor K Archer, Noboru Sato

“…<h4>Background</h4>Embryonic stem (ES) cells self-renew as coherent colonies in which cells maintain tight cell-cell contact. Although intercellular communications are essential to establish the basis of cell-specific identity, molecular mechanisms underlying intrinsic cell-cell interactions in ES cells at the signaling level remain underexplored.…”
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Long term exposure to multiple environmental stressors induces mitochondrial dynamics imbalance in testis: Insights from metabolomics and transcriptomics by Shiqin Jiang, Tianli Nong, Ting Yu, Zhiyan Qin, Junyuan Huang, Zhaokun Yin, Shiqi Luo, Yating Lai, Jing Jin

“…Specifically, corticosterone treatment decreased tight junction protein expression, increased reactive oxygen species (ROS) levels, and impaired mitochondrial morphology and function, as evidenced by reduced mitochondrial membrane potential, elevated calcium ion concentration, and shortened mitochondrial length and network in vitro. …”
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Effect of substituting crude palm oil with saponified black soldier fly larvae (Hermetia illucens l.) oil on performance and digestive tract characteristics of broiler chickens by Ega Anggi Lestari, Chusnul Hanim

“…In addition, lauric acid can function as an antimicrobial and immunomodulator. As an antimicrobial, it can inhibit the activity of enzymes that play a role in energy production and nutrient transport. …”
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Optimal Investment for Insurers with the Extended CIR Interest Rate Model by Mei Choi Chiu, Hoi Ying Wong

“…After solving the stochastic optimal control problem with the HJB framework, we offer a verification theorem by proving the uniform integrability of a tight upper bound for the objective function.…”
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Flake Electrical Conductivity of Few-Layer Graphene by Hamze Mousavi, Jabbar Khodadadi

“…The Kubo formula for the electrical conductivity of per stratum of few-layer graphene, up to five, is analytically calculated in both simple and Bernal structures within the tight-binding Hamiltonian model and Green's function technique, compared with the single-layer one. …”
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SMG-1 and mTORC1 act antagonistically to regulate response to injury and growth in planarians. by Cristina González-Estévez, Daniel A Felix, Matthew D Smith, Jordi Paps, Simon J Morley, Victoria James, Tyson V Sharp, A Aziz Aboobaker

“…Planarian flatworms are able to both regenerate their whole bodies and continuously adapt their size to nutrient status. Tight control of stem cell proliferation and differentiation during these processes is the key feature of planarian biology. …”
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Aplysin Retards Pancreatic Necrosis and Inflammatory Responses in NOD Mice by Stabilizing Intestinal Barriers and Regulating Gut Microbial Composition by Ying Liu, Xinyue Cui, Ming-Qing Gao, Meilan Xue, Hongwei Xu, Zhishang Chang, Yushan Jiang, Hui Liang

“…Results showed that NOD mice at 12 weeks of age showed obvious spontaneous pancreatic necrosis, damaged tight junctions of intestinal epithelia, and widened gaps in tight and adherens junctions. …”
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Neurovascular Restoration by Treadmill Exercise Attenuates Age-Related Cognitive Decline in Mice by Jae Min Lee, Da-Eun Sung, You Jung Choi, Seung Geun Yeo, Youn-Jung Kim

“…Results Treadmill exercise significantly improved cognitive function, as indicated by increased latency time in the passive avoidance test. …”
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Shengui Sansheng San alleviates the worsening of blood–brain barrier integrity resulted from delayed tPA administration through VIP/VIPR1 pathway by Jiacheng Hu, Yiyang Li, Xingping Quan, Yan Han, Jinfen Chen, Mengchen Yuan, Ying Chen, Manfei Zhou, Enze Yu, Jiahao Zhou, Dawei Wang, Ruibing Wang, Yonghua Zhao

“…Conclusion SSS alleviates the worsening of BBB integrity resulted from delayed tPA administration, reduces hemorrhagic transformation and infarction volume, and ameliorates brain blood flow and neurological function in AIS mice. The mechanisms are associated with the activation of VIP/VIPR1 pathway to enhance BMECs viability and maintain tight junction phenotype. …”
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