Correlates of Calcaneal Quantitative Ultrasound Parameters in Patients with Diabetes: The Study on the Assessment of Determinants of Muscle and Bone Strength Abnormalities in Diabe... by Francesco Conti, Stefano Balducci, Luca Pugliese, Valeria D’Errico, Martina Vitale, Elena Alessi, Gerardo Salerno, Carla Iacobini, Stefano Menini, Lucilla Bollanti, Antonio Nicolucci, Giuseppe Pugliese

“…This study aimed at assessing the correlates of calcaneal QUS parameters in diabetic subjects encompassing various degrees of micro and macrovascular complications and a wide-range of peripheral nerve function. Methods. Four hundred consecutive diabetic patients were examined by QUS to obtain values of broadband ultrasound attenuation (BUA), the speed of sound (SOS), quantitative ultrasound index (QUI), and BMD. …”
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Association of TNF-857C>T, TNFRSF1A36A>G, and TNFRSF1B676T>G Polymorphisms with Ischemic Stroke in a Greek Population by Sofia Markoula, Anthoula Chatzikyriakidou, Sotirios Giannopoulos, Kargiotis Odysseas, Sofia Markou, Konstantinos Vemmos, Ioannis Georgiou, Athanassios P. Kyritsis

“…Materials and Methods. One hundred seventy-three patients with first ever ischemic stroke of solely atherosclerotic etiology in Northwest Greece and a control group of 179 healthy unrelated subjects were evaluated. …”
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The roles of impulsivity, comorbid ADHD, and borderline personality disorder in patients with bulimia nervosa by Susanne Gilsbach, Julia Leuchtenberger, Beate Herpertz-Dahlmann, Ulrich Voderholzer, Kerstin Konrad, Georg von Polier, Jochen Seitz, Manfred Fichter

“…The aim of this study was to explore comorbidities of BN with ADHD and BPD as well as the contribution of impulsivity as an underlying trait linking these disorders. Methods Hundred and fifteen females with BN and 98 healthy matched controls (HC) (age range between 16 and 48 years) were assessed regarding adult and childhood-ADHD, personality disorders and impulsivity. …”
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Serum metabolomic profiling for predicting therapeutic response and toxicity in breast cancer neoadjuvant chemotherapy: a retrospective longitudinal study by Zhihao Fang, Guohong Ren, Shouyu Ke, Qimin Xu, Yuhua Chen, Xiaoyuan Shi, Cheng Guo, Jian Huang

“…Although metabolic changes during cancer treatment are crucial determinant factors in therapeutic responses and toxicities, related clinical research remains limited. Methods One hundred paired blood samples were collected from 50 patients with LABC before and after a complete NACT treatment cycle. …”
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The Effect of Guidance regarding Home Exercise and ADL on Adolescent Females Suffering from Adverse Effects after HPV Vaccination in Japanese Multidisciplinary Pain Centers by Takahiro Ushida, Masahiko Shibata, Masaki Kitahara, Shoji Yabuki, Masahiko Sumitani, Takanori Murakami, Masako Iseki, Masako Hosoi, Hiroaki Shiokawa, Tomoko Tetsunaga, Hiroyuki Nishie, Sei Fukui, Motohiro Kawasaki, Sinsuke Inoue, Makoto Nishihara, Shuichi Aono, Tatunori Ikemoto, Takashi Kawai, Young-Chang Arai

“…To survey the characteristics of and the effects of cognitive behavioral therapy on adolescent female suffering from the AEs in Japanese multidisciplinary pain centers. Methods. One hundred and forty-five patients suffering from the AEs were reviewed retrospectively and 105 patients of them were provided guidance on home exercise and activities of daily living based partially on a cognitive-behavioral approach. …”
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Achieving the Recommended Endotracheal Tube Cuff Pressure: A Randomized Control Study Comparing Loss of Resistance Syringe to Pilot Balloon Palpation by Fred Bulamba, Andrew Kintu, Nodreen Ayupo, Charles Kojjo, Lameck Ssemogerere, Agnes Wabule, Arthur Kwizera

“…The pressures measured were recorded. Results. One hundred seventy-eight patients were analyzed. 66.3% (59/89) of patients in the loss of resistance group had cuff pressures in the recommended range compared with 22.5% (20/89) from the pilot balloon palpation method. …”
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Untreated Active Tuberculosis in Pregnancy with Intraocular Dissemination: A Case Report and Review of the Literature by Shadi Rezai, Stephen LoBue, Daniel Adams, Yewande Oladipo, Ramses Posso, Tiffany Mapp, Crystal Santiago, Manisha Jain, William D. Marino, Cassandra E. Henderson

“…Tuberculosis (TB) is a disease that affects hundreds of millions of people across the world. However, the incidence in developed countries has decreased over the past decades causing physicians to become unfamiliar with its unspecific symptoms. …”
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Damage Evolution and Failure Precursor of Rock-like Material Under Uniaxial Compression Based on Strain Rate Field Statistics by Jin Jin, Ping Cao, Jun Zhang, Yanchao Wang, Chenxi Miao, Jie Li, Xiaohong Bai

“…The volume strain rate field data before the peak stress have been obtained from two hundred measurement circles across each model. The strain rate field data have been firstly statistically analyzed to explore the failure precursor based on the intact model and 45° flaw model and then compared to find the influence of the pre-existing flaw on the damage evolution and precursor signal. …”
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Influence of Medication on Fatigue Six Months after Stroke by Amélie Ponchel, Julien Labreuche, Stéphanie Bombois, Christine Delmaire, Régis Bordet, Hilde Hénon

“…Medical history, vascular risk factors, depression, anxiety, and sleep disturbances were evaluated. One hundred and fifty-three patients were included: 52.9% presented PSF. …”
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The impact of chronic airway disease on symptom severity and global suffering in Canadian rhinosinusitis patients by Kimberly Luu, Jason Sutherland, Trafford Crump, Giuping Liu, Arif Janjua

“…The impact of pulmonary comorbidity on SNOT-22 scores, pain and depression was measured. Results Two hundred fifthy-three patients were included in the study, 91 with chronic pulmonary comorbidity. …”
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Targeted screening and profiling of massive components of colistimethate sodium by two-dimensional-liquid chromatography-mass spectrometry based on self-constructed compound databa... by Xuan Li, Minwen Huang, Yue-Mei Zhao, Wenxin Liu, Nan Hu, Jie Zhou, Zi-Yi Wang, Sheng Tang, Jian-Bin Pan, Hian Kee Lee, Yao-zuo Yuan, Taijun Hang, Hai-Wei Shi, Hongyuan Chen

“…This profiling method was highly efficient and could distinguish hundreds of components within 3 h, providing reliable results for quality control of this kind of complex drugs.…”
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GPA-MDS: A Visualization Approach to Investigate Genetic Architecture among Phenotypes Using GWAS Results by Wei Wei, Paula S. Ramos, Kelly J. Hunt, Bethany J. Wolf, Gary Hardiman, Dongjun Chung

“…Genome-wide association studies (GWAS) have identified tens of thousands of genetic variants associated with hundreds of phenotypes and diseases, which have provided clinical and medical benefits to patients with novel biomarkers and therapeutic targets. …”
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Hierarchical accompanying and inhibiting patterns on the spatial arrangement of taxi local hotspots by Xiao-Jian Chen, Quanhua Dong, Changjiang Xiao, Zhou Huang, Keli Wang, Weiyu Zhang, Yu Liu

“…Previous studies have primarily explored large-scale hotspots through visual analysis or simple indices, which typically spans hundreds or even thousands of meters. However, the spatial arrangement patterns of small-scale hotspots representing specific popular pick-up and drop-off locations have been largely overlooked. …”
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Low IL-6, IL-10, and TNF-α and High IL-13 Cytokine Levels Are Associated with Severe Hepatic Fibrosis in Schistosoma mansoni Chronically Exposed Individuals by Mable M. Mutengo, Takafira Mduluza, Paul Kelly, James C. L. Mwansa, Geoffrey Kwenda, Patrick Musonda, James Chipeta

“…We therefore investigated the role of selected T-helper (Th)1, Th2, and Th17 cytokines in relation to hepatic fibrosis severity among individuals resident in a hyper-Schistosoma mansoni endemic region of Western Zambia. Two hundred and forty-four S. mansoni infected individuals with and without fibrosis were analysed for cytokine profiles. …”
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Phenotypic and Molecular Characterization of β-Lactamases among Enterobacterial Uropathogens in Southeastern Nigeria by M. C. Ugwu, M. Shariff, C.M. Nnajide, K Beri, U. M. Okezie, I. R. Iroha, C. O. Esimone

“…The aim of the study was to characterize enterobacterial uropathogens with respect to drug resistance. One hundred (100) enterobacterial uropathogens were studied. …”
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Simplified Assessment of Antiretroviral Adherence and Prediction of Virological Efficacy in HIV-Infected Patients in Cambodia by Olivier Segeral, Yoann Madec, Boroath Ban, Vara Ouk, Chan Roeurn Hak, Clotilde Le Tiec, Eric Nerrienet, Cécile Goujard, Anne Marie Taburet, Jean Francois Delfraissy, Arnaud Fontanet

“…The survey was based on a self-report questionnaire, drug assay, MCV measurement, visual analog scale, and viral load HIV RNA. Results. Two hundred fifty-nine patients treated for a median of 16 months participated in the survey. …”
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Influence of Channel Regulating Structures on the Transportation and Dissipation of Supersaturated Total Dissolved Gas by Yun Qing, Qian Ma, Ran Li, Xia Shen, XuJin Zhang, LinFeng Han

“…Thus, the elevated TDG may remain through the water body for hundreds of kilometers downstream and lead to gas bubble disease (GBD) and even mortality in fish. …”
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Glucocorticoid receptor: translocation from the cytoplasm to the nuclei, chromatin and intranuclear chaperone cycles by V. M. Merkulov, N. V. Klimova, T. I. Merkulova

“…Glucocorticoid receptor (GR) is a ligand-dependent transcription factor, involved in the regulation of hundreds of genes. In the absence of any ligand, GR resides in the cytoplasm where it is sequestered in a multimeric chaperone complex consisting of hsp90, hsp70, p23, Hop, FKBP51, FKBP52, etc. …”
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A global approach to detecting and characterizing water leakage in a concrete bridge deck: Parametric study to validate an adapted Full-Waveform Inversion method by Viktoriia Buliuk, Amine Ihamouten, Christophe Heinkele, Xavier Dérobert

“…In contrast, other methods typically require several hundred A-scans. This efficiency is achieved due to the two-dimensional nature of the layer system. …”
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Validated HPLC Methodology for Pregabalin Quantification in Human Urine Using 1-Fluoro-2,4-dinitrobenzene Derivatization by Mohamedsaid mostafa Said Mostafa, Hosam Abdel Fattah Mohamed Elshebiny, Olfat Elsayed Mostafa, Shimaa Talaat Elsayed, Mohamed Abdelizm Abdelaziz

“…This study aimed to validate a simple, sensitive, and accurate method for PGB quantification in human urine using the HPLC technique with 1-Fluoro-2, 4-dinitrobenzene used as a derivatizing agent. One hundred and twenty urine samples were analyzed by a reversed-phase (C18) column and a mixture of acetonitrile and 50 mM KH2PO4 (pH 2.5) (60:40, v/v) as mobile phase and the flow rate was 1 ml/min and the UV detector wavelength was set to 360nm. …”
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