Novel complex medication containing medium chain triglycerides for the treatment of dry eye by T.N. Safonova, G.V. Zaytseva, K.Yu. Kravets, N.B. Polyakov

“…Tearscopy revealed a significant improvement in the tear film lipid layer in group 1 (an increase in the lipid distribution coefficient and lipid thickness by 0.2 and 0.03, respectively) in comparison to group 2 (an increase by 0.1 and 0.02). …”
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Circumscribed choroidal hemangioma: clinical course and treatment by A.F. Brovkina, A.S. Stoyukhina, I.V. Musatkina

“…</i> </p> <p> <i><b>Conclusion</b>: CCH is a torpid benign choroidal tumor with good vision at baseline which requires dynamic follow-up and OCT to monitor retina, retinal detachment height, and tumor thickness. Progressive loss of vision and progressive retinal detachment are considered indications for treatment. …”
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Blinking characteristics analyzed by a deep learning model and the relationship with tear film stability in children with long-term use of orthokeratology by Yue Wu, Siyuan Wu, Yinghai Yu, Yinghai Yu, Xiaojun Hu, Ting Zhao, Yan Jiang, Bilian Ke

“…The OSDI scores, conjunctival redness, lipid layer thickness (LLT), and tear meniscus height did not change significantly between two groups. …”
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Investigating the Role of Artificial Intelligence Enablers and Companies' Readiness in Adopting an Artificial Intelligence-integrated Customer Relationship Management System by Soheila Mohammadzadeh Vanestan, Rahim Abedi

“…To test the research hypotheses, structural equations were tested using a partial least squares approach, employing the third version of SMART-PLS software. FindingsThe results showed that AI empowerment (including technology roadmap, attitude, and professional expertise) and AI readiness (including awareness, infrastructure, and technical level) affect adopting artificial intelligence integrated with customer relationship management systems. …”
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Pengaruh Pesan Keagamaan Dalam Nadham Maulid Al-Dhiyâ’ Al-Lâmi’ Terhadap Jamaah Majelis Taklim Al-Hidayat Gampong Peulanggahan Banda Aceh; Kajian Ritual Effect by Syarifuddin, Cut Masthura Rahmatillah, Abd Razak, Rahma Salbiah

“…The findings are as follows: First, the content includes messages of monotheism, praise for the Prophet, nobility, lineage, praises for the birth, and prophetic history; second, the religious impact on the lives of the congregation and the Acehnese community includes increased faith, love for the Prophet, adherence to Allah’s Sharia and the Prophet’s Sunnah, blessed life, improved morals, psychological therapy, and strengthened social relationships; third, the ritual art of reciting Nadham Maulid Al-Dhiyâ’ Al-Lâmi’ can be preserved due to the attraction to the familial network of the Prophet known as Ahlul Bait, as well as the traditional Hadrah music تركز هذه الدراسة على تحليل الرسائل الدينية في الطقوس القرائية لنظم مولد الضياء اللامع، وتأثيره على جماعة مجلس التعليم الهدى والمجتمع، وكذلك دوافع واستراتيجيات الحفاظ عليه باستخدام نهج تأثير الطقوس. …”
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Effects of Duhuo Jisheng Decoction on Calcium Homeostasis and Apoptosis of Chondrocytes under Endoplasmic Reticulum Stress by Qing LIN, Wenyi WANG, Danhong PAN, Yanfeng HUANG, Changlong FU, Jinxia YE

“…Objective:To observe the effect of Duhuo Jisheng decoction on the balance of calcium homeostasis and apoptosis of chondrocytes under endoplasmic reticulum stress(ERS), and to preliminarily explore its mechanism of preventing and treating osteoarthritis.Methods:A steady chondrocyte in vitro culture system was established by using 4-week-old SD rat knee cartilage, and identify the third generation chondrocyte by toluidine blue staining.The 25 μmol/L Thapsigargin(TG)was used to induce chondrocyte in vitro culture to produce endoplasmic reticulum stress(ERS), incubate it in Duhuo Jisheng Decoction(100, 200, 400 μg/mL)for 24 hours after induction.The cells were divided into the blank group, the model group, the low-dose Duhuo Jisheng decoction group, the medium-dose Duhuo Jisheng decoction group, and the high-dose Duhuo Jisheng decoction group.Then morphological changes of chondrocytes were observed respectively by inverted microscope, viability of chondrocyte in each group was examined by CCK-8 method, chondrocyte apoptosis was observed by Hoechst 33342 staining and real-time dynamic changes of intracellular Ca²⁺concentration was examined by double turntable laser confocal microscope.Results:①The morphology of chondrocytes: the cells in the blank group grew in a single-layer paving stone shape, while the cells in the model group increased in a polygonal shape, the pseudopodia increased, the gaps widened, and the number of cells decreased significantly.Compared with the model group, the number of cells in the three dose groups of Duhuo Jisheng decoction(100, 200, 400 μg/mL)increased significantly and the cytoplasm was uniform.The activity of chondrocytes in each group: compared with the blank group, the survival rate of the model group was lower, and the difference was statistically significant(<italic>P</italic>&lt;0.05).The absorbance of each concentration group of Duhuo Jisheng decoction increased with the increase of concentration, and the difference was statistically significant compared with the model group(<italic>P</italic>&lt;0.05).③Apoptosis of chondrocytes: the number of apoptosis in the model group was significantly increased, and the degree of pyknosis of the nucleus was obvious, and some of them were a high density of bright blue or half moon-shaped.The number of apoptotic cells in each dose group of Duhuo Jisheng decoction was significantly reduced, only a few apoptotic cells showed a high density of bright blue or half-moon shape, and the number of apoptosis decreased with the increase of the concentration of Duhuo Jisheng decoction, showing a certain dose-effect relationship.④The changes of intracellular calcium ion concentration: the calcium ion fluorescence intensity of the cells in the blank group was weaker and more uniform, maintaining a stable state.The calcium ion release of the model group was significantly increased, and the fluorescence intensity was enhanced.The fluorescence spectrum showed that calcium sparks were more frequent.Compared with the blank group, the difference was statistically significant(<italic>P</italic>&lt;0.05).Chondrocytes in the medium and high-dose Duhuo Jisheng decoction groups could quickly return to calcium homeostasis, and calcium sparks were significantly reduced.Although there were still some calcium sparks in the low-concentration Duhuo Jisheng decoction group, the fluorescence intensity was significantly weaker than the model group.Conclusion:Duhuo Jisheng decoction has an inhibitory effect on the apoptosis of chondrocyte induced by TG, the mechanism may be that Duhuo Jisheng decoction can alleviate endoplasmic reticulum stress by regulating calcium balance, thus inhibiting the apoptosis of chondrocyte.…”
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About relevance of fundamentalisation of mathematical training of students of the pedagogical directions during the digital era by E. A. Perminov, D. D. Gadjiev, M. M. Abdurazakov

“…As a result of a digital era, general-education concepts have already become the key concepts of various sections of mathematics, therefore, it is necessary to start a general introduction to the study of these concepts at the stages of school education.It is highlighted that fundamentalisation of mathematical preparation plays the leading role in the development of logical and professional innovative thinking of students through the understanding of multifunctional structures and schemes (as means and knowledge methods) similar to mathematical structures and schemes. …”
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Determinants of Parental Attitudes towards Children’s Vaccination in Lithuania: An Online Survey by Kamilė Čeponytė, Eglė Narkevičiūtė, Aušra Beržanskytė, Sigita Burokienė

“…The price of vaccines also had an impact on immunisation rates – more than one-third of the vaccine supporting parents indicated that the cost of paid vaccinations was too high. …”
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Experimental Study of Steady Blowing from the Trailing Edge of an Open Cavity Flow by Naser Al Haddabi, Konstantinos Kontis, Hossein Zare-Behtash

“…The study found that increasing the jet momentum flux caused a significant increase in thickness and deflection of the cavity separated shear layer. …”
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Meta-Analysis of Acupuncture on Physical and Activity Participation Related Functions of Children with Autism Spectrum Disorders by CHEN Qiang, KAN Mengfan, JIANG Xiaoyu, LIU Huifen, SUN Wenyu, BI Hongyan

“…The primary outcome measures included autism behavior checklist (ABC) score, autism treatment evaluation checklist (ATEC) score, psycho educational profile-Third Edition (PEP-3) score, children's sleep habits questionnaire (CSHQ) score, Gesell developmental schedules (GDS) score, functional independence measure for children (WeeFIM) score, Reynell developmental language scales (RDLS) score and Arabic language testing (ALT) score. …”
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Changes in infant respiratory pathogens pre-, during, and post-COVID-19 non-pharmacological interventions in Beijing by Tongying Han, Yajuan Wang, Di Zhang, Ying Li, Li Zhang, Jin Yan, Chi Li, Shengnan Yang, Litao Guo, Huijuan Yan

“…After the termination of NPIs, the positive detection rate decreased in the first quarter but increased in the second, third, and fourth quarters, with a statistically significant difference (P < 0.05). …”
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Insiden Malaria di Puskesmas Sungai Durian dan Puskesmas Talawi Kota Sawahlunto Bulan Oktober 2011 sampai Februari 2012 by Mareza Dwithania, Nuzulia Irawati, Rosfita Rasyid

“…The data was obtained by microscopic examination of thick and thin blood preparations from peripheral blood samples that had been daubed with Giemsa staining. …”
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Hubungan Paparan Asap Rokok Lingkungan dengan Kejadian Dismenorea Primer by Rifki YS, Ermawati Ermawati, Irvan Medison

“…The results of chi-square statistical test showed that environmental tobacco smoke exposure ( p = 0.020 ) had a relationship with the incidence of primary dysmenorrhoea .From the results, it can be concluded that the Student Pre-clinic Medical Education Program Faculty of Medicine, University of Andalas 2013-2014 school year are subjected to one-third of primary dysmenorrhea and environmental exposure to cigarette smoke, and there is a significant relationship between environmental tobacco smoke exposure with the incidence of primary dysmenorrhoea. …”
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Designing a defensive silence failure model of creative employees in organizations by Azam Khosravi, karam khalili, Esfandyar Mohammadi

“…The 20 main themes that have been identified as influencing factors on breaking the defensive silence of creative employees in government organizations are: facilitating policies, motivational factors, job security, collaborative management, governance of meritocracy, leadership style, improvement of individual skills, organizational learning, strengthening professional ethics, quality of relationships, health of relationships, mutual trust, spirituality in the workplace, creative and critical atmosphere, cooperation culture, consulting and positive organizational psychology, reducing psychological pressures, creating attitudinal changes, changing organizational strategies, and strengthening strategic thinking.Extended abstractIntroductionIn organizations, employees play a very important role. …”
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Applying the metacombination approach in order to design the native model of new product development by seyed Rohollah faraji, Hoseain Adab, jalal HaghighatMonfared

“…The proposed framework, called Gateway-Completed Phase, integrates the development process with design thinking and lean deployment approaches. The framework consists of six steps and five gates, and focuses on critical thinking to help entrepreneurs avoid mental traps and make sound decisions. …”
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Designing the strategic model of online banking relational marketing in the fourth industrial revolution with the foundation's data approach. by Aliasghar Atarodi, arezo ahmadi danyali, nader gharib nawaz

“…Oil and electricity facilitated mass production in the second industrial revolution, and information technology was used to automate production in the third industrial revolution. Finally, in the fourth industrial revolution, attention was paid to increasing the cognitive power of human productions and this power was strengthened (Xu et al., 2018). …”
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Research Progress and Prospect of Multi-robot Collaborative SLAM in Complex Agricultural Scenarios by MA Nan, CAO Shanshan, BAI Tao, KONG Fantao, SUN Wei

“…Secondly, the combination of deep learning and reinforcement learning techniques is expected to empower robots to better interpret environmental patterns, adapt to dynamic changes, and make more effective real-time decisions. Thirdly, large language models will enhance human-robot interaction by enabling natural language commands, improving collaborative operations. …”
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Nilai Diagnostik Metode “Real Time” PCR GeneXpert pada TB Paru BTA Negatif by Eka Kurniawan, Raveinal Raveinal, Fauzar Fauzar, Zulkarnain Arsyad

“…TB is still a global health problem. Approximately one third of the world population is infected by Mycobacterium tuberculosis and the source of infection came from smear positive and negative patient. …”
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The Use of Zeolit and Activated Carbon on Packing System of Corydoras aenus by E. Supriyono, E. Supendi, K. Nirmala

“…Suitable and efficient packing technology is very needed to send live fish for long time transportation.  Two third of packing plastic volume was filled by oxygen, and Corydoras aenus 20 fish/pack.  …”
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The very-high-resolution configuration of the EC-Earth global model for HighResMIP by E. Moreno-Chamarro, E. Moreno-Chamarro, E. Moreno-Chamarro, T. Arsouze, T. Arsouze, M. Acosta, P.-A. Bretonnière, M. Castrillo, E. Ferrer, A. Frigola, D. Kuznetsova, E. Martin-Martinez, P. Ortega, S. Palomas

“…Other biases persist or worsen with increased resolution from LR to VHR, such as the warm bias over the tropical upwelling region and the associated cloud cover underestimation, a precipitation excess over the tropical South Atlantic and North Pacific, and overly thick sea ice and an excess in oceanic mixing in the Arctic. …”
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