The combination of rAAV pseudo-lipid nanoparticle and triamcinolone acetonide enables multi-administration to liver by Chunmei Gan, Mi Leng, Yu Liu, Zhaoyue Zheng, Siwu He, Wen Qiao, Lin Xiao, Yao Xiao, Jingya Ye, Lixing Zhou, Jiao Zhou, Boduan Xiao, Wenxin Zhao, Jiamei Yang, Aohan Wu, Huiyuan Zhang, Hongbo Hu, Xiaobo Cen, Zhiyong Qian, Haohao Dong, C. Alexander Valencia, Lunzhi Dai, Hoi Yee Chow, Lei Zhang, Biao Dong

“…The plasma hFIX protein was enhanced to 15.1 μg/mL and the liver bioluminescence was elevated to 1.4 × 108 p/s/cm2/sr following the second and third administrations, with weaker levels in LNP encapsulation (1.9 μg/mL, 2.1 × 104 p/s/cm2/sr) and TAC treatment (3.0 μg/mL, 6.1 × 104 p/s/cm2/sr) groups. …”
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PRAGMATIZMO RECEPCIJA POSTFILOSOFIJOJE by Jūratė Baranova

“…How and why the idea of deconstruction corresponds to the paradigm of postmodern thinking? What are the common points of view between the "mystery", which is presupposed at derridean ethics of deconstruction and the "jump across the abyss" which is the main leitmotif in William James's doctrine on the will to believe? …”
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Phytochemical analysis and anti-aging efficacy of two Egyptian sweet potato cultivars in a d-galactose-induced skin aging model by Rehab M. Elgabry, Ghada A. Fawzy, Khaled M. Meselhy, Nehal M. Ramadan, Nihal Farid Younes, Areej M. Al-Taweel, Shagufta Perveen, Mohamed S. Sedeek

“…Restoration of skin thickness and collagen content was observed in the 5% Abees group, while both Abees and A195 caused a noticeable concentration-dependent decrease in the skin SMAD7 expression. …”
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Integrating biodiversity assessments into local conservation planning: the importance of assessing suitable data sources by Ferraille, Thibaut, Kerbiriou, Christian, Bigard, Charlotte, Claireau, Fabien, Thompson, John D.

“…Second, the collection of individual databases at the country scale is necessary to complete local data and ensure the suitability of SDM in a local context. Third, a data driven approach can lead to the use of notably different species communities to identify priority conservation areas when compared to the community in the original database. …”
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Nonharmonic Control of the Blade-Vortex Interaction Noise of Electrically Controlled Rotor by Kewei Li, Taoyong Su, Yang Lu, Qijun Zhao

“…Subsequently, the effect of the third quadrant flap nonharmonic control on BVI noise on the retreating side of the sample electrically controlled rotors is investigated. …”
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Formation of strength abilities in students of agricultural university by Antsyperov, Vladimir V., Sychev, Pavel A., Vlasova, Tatyana N., Kozlova, Tatyana N., Popova, Olga M.

“…The obtained results showed that the strength development of students increases from course to course, which is clearly expressed by the average total results of relative strength: the average coefficient according to the GL Points-IPF formula in the first year was 214.0 ± 6.4, in the second year it was already 219.2 ± 7.7, and on the third reached 237.6 ± 7.6 points, which is obviously due to the use of not only strength exercises, but also age related changes, characterized by an increase in muscle mass and its qualitative changes. …”
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Establishing a preoperative predictive model for gallbladder adenoma and cholesterol polyps based on machine learning: a multicentre retrospective study by Yubing Wang, Chao Qu, Jiange Zeng, Yumin Jiang, Ruitao Sun, Changlei Li, Jian Li, Chengzhi Xing, Bin Tan, Kui Liu, Qing Liu, Dianpeng Zhao, Jingyu Cao, Weiyu Hu

“…The model-selected features included gallbladder wall thickness, polyp size, polyp echo, and pedicle. Evaluation through external cohort validation, calibration curves, and clinical decision curves further confirmed its excellent predictive ability for distinguishing gallbladder adenomas from cholesterol polyps. …”
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A novel approach to completely alleviate peripheral neuropathic pain in human patients: insights from preclinical data by Safa Shehab, Mohammad I. K. Hamad, Bright Starling Emerald

“…The effects of this treatment were specific to unmyelinated fibers (responsible for pain sensation), while thick myelinated nerve fibers (responsible for touch and mechanoreceptor sensations) remained intact. …”
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E‐CHAIM as a Model of Total Electron Content: Performance and Diagnostics by D. R. Themens, Ben Reid, P. T. Jayachandran, Bion Larson, A. V. Koustov, Sean Elvidge, A. M. McCaffrey, Chris Watson

“…Conjunctions with mid‐latitude ionosondes demonstrate that E‐CHAIM's errors appear to result from compounding same‐signed errors in its NmF2, hmF2, and topside thickness at these latitudes. Overall, E‐CHAIM exhibits strong performance within the polar cap and auroral oval but performs comparably to the IRI at sub‐auroral latitudes.…”
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Investigating the Effect of Empirical Interventions on Improving the Historical Urban Texts of Iran and the World A Comparative Study of Historical Cities of Birjand in Iran and Pe... by nazli pakro, arash saghafi asl

“…The second stage of the field survey is weighted and the third stage with appropriate and desirable strategic scenarios for the development of the historical texture and reduction and redevelopment of the presentation. …”
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PDIA3 rs2788: An Independent Risk Factor for Hypertension and Its Interaction With Antihypertensive Medications by Hongtao Lan, Yingbin Xi, Baoxu Kang, Zhoujie Tong, Jie Peng, Wei Zhang, Ming Zhong, Huiping Gong, Zhihao Wang

“…Second, key gene polymorphism on PDIA3 was identified using online databases and analyzed with Haploview software. Third, multivariate‐adjusted logistic regression analyses were employed to evaluate the associations between PDIA3 rs2788 and hypertension. …”
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Academic burnout and its related factors among dental students in southeast Iran: a cross-sectional study by Mehrnaz Karimi Afshar, Sobhan Ghorbani Nejad, Marzieh Karimi Afshar

“…Methods and materials This cross-sectional study included 180 clinical dentistry students in their third year and above at Kerman Dental Faculty during the academic year 2022–2023. …”
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Cardiac Resynchronization Therapy Reduces Metaboreflex Contribution to the Ventilatory Response in Heart Failure Population by Jérémie Jaussaud, Laurie Aimable, Pierre Bordachar, Pierre Dos Santos, Laurent Barandon, Philippe Ritter, Raymond Roudaut, Hervé Douard

“…Metaboreflex contribution to the ventilatory response was assessed as the difference in ventilatory data at the third minute during recovery between the two tests (Δ). …”
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Experimental Study on Impermeability Law of Aquiclude Reconstructed by Mudstone of External Dump in Arid Zone by Li Ma, Chendong Liu, Yinli Bi, Suping Peng, Kaisheng Jiang, Hui Zhang, Qiang Luo, Fei Xue, Tianxin Xu, Tianxiang Li, Jing Wu, Jiahao Tian, Dongxu Zhang

“…And the particle size of 0.5 mm, 1 mm, and 2 mm and the thickness of 5 cm, 10 cm, and 20 cm rock samples were selected to conduct the indoor soil column experiment. …”
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Deformation and Rupture of Thin Steel Plates due to Cumulative Loading from Underwater Shock and Bubble Collapse by Julian J. Lee, Malcolm J. Smith, James Huang, Geoffrey T. Paulgaard

“…The test specimens consisted of plates 0.76 mm and 1.21 mm thick made of either ASTM A1008 mild steel or 350 WT structural-grade steel with a low-temperature notch-toughness requirement. …”
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Features and evolutionary adaptations of the mitochondrial genome of Garuga forrestii W. W. Sm by Rong Chen, Rong Chen, Rong Chen, Rong Chen, Rui Rao, Rui Rao, Rui Rao, Rui Rao, Chun Wang, Chun Wang, Chun Wang, Chun Wang, Dongbo Zhu, Dongbo Zhu, Dongbo Zhu, Dongbo Zhu, Fen Yuan, Fen Yuan, Fen Yuan, Fen Yuan, Liangliang Yue, Liangliang Yue, Liangliang Yue, Liangliang Yue

“…Additionally, a significant A/T bias is observed at the third codon position. Phylogenomic analysis supports the APG IV classification, with no evidence of horizontal gene transfer.DiscussionThis mitochondrial genome offers valuable insights into the adaptive mechanisms and evolutionary processes of Garuga forrestii. …”
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Effect of Multiradiance Low-Level Laser Therapy and Topical Silver Sulfadiazine on Healing Characteristics of Dermal Wounds in Marine Toads (Rhinella marina) by Kate E. Archibald, Tara Harrison, Brigid Troan, Dustin Smith, Larry J. Minter

“…This pilot study evaluated the effects of repeated treatments of low-level laser therapy or topical SSD on second-intention healing characteristics of surgically induced full-thickness dermal wounds in 33 adult wild-caught marine toads. …”
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OMERACT GCA phantom project: validation of a 3D-printed ultrasound training phantom for diagnosis of giant cell arteritis by Annamaria Iagnocco, Christian Dejaco, Richard J Wakefield, Stavros Chrysidis, Sara Monti, Thomas Daikeler, Esperanza Naredo, Lene Terslev, Wolfgang A Schmidt, Alojzija Hočevar, Christina Duftner, Chetan Mukhtyar, Valentin Sebastian Schäfer, Kate Smith, Eugenio De Miguel, Marcin Milchert, Andreas P Diamantopoulos, Pierluigi Macchioni, Uffe Møller Døhn, George A Bruyn, Verena Tischler, Wolfgang Hartung, Markus Aschwanden, Giuseppe Germanò, Aaron Juche, Rositsa Karalilova, Dennis Boumans, Kresten Krarup Keller, Luca Seitz, Berit Nielsen, Tobias Schremmer, Florian Recker, Cees Haagsma, Pantelis Karakostas, Borsha Sarker

“…This study tested the reliability of ultrasonography findings and measurements of the intima-media thickness (IMT) among ultrasonography experts by using phantoms of the axillary (AA) and temporal arteries (TA) created with high-resolution 3D printing.Methods Twenty-eight participants from 12 European countries received eight sets of phantoms of the AA and the superficial TA (including common, frontal and parietal branches), which were examined in a blinded fashion according to a predefined protocol and evaluated based on Outcome Measures in Rheumatology (OMERACT) GCA ultrasound definitions. …”
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The current status and influencing factors of diabetes knowledge among non-endocrinology nurses of tertiary general hospitals: a cross-sectional survey study by Jia Song, Su Li, Chongcai Gu, Shiyan Zhao, Xing Li, Siqin Liu, Jinmei Tuo, Shiming Huang

“…Abstract Background Every year, more than one-third of diabetes patients experience various acute and chronic complications, leading to the presence of diabetes patients in various departments of the hospital. …”
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Trimethylamine Oxidation into the Proatherogenic Trimethylamine N-Oxide Is Higher in Coronary Heart Disease Men: From the CORDIOPREV Study by Helena Garcia-Fernandez, Juan F. Alcala-Diaz, Gracia M. Quintana-Navarro, Javier Lopez-Moreno, Diego Luque-Cordoba, Eugenia Ruiz-Diaz Narvaez, Antonio P. Arenas-de Larriva, Francisco M. Gutierrez-Mariscal, Jose D. Torres-Peña, Diego Rodriguez-Cano, Raul M. Luque, Feliciano Priego-Capote, Jose Lopez-Miranda, Antonio Camargo

“…The carotid study was ultrasonically assessed bilaterally by the quantification of intima-media thickness of both common carotid arteries (IMT-CC). …”