Comprehensive bioinformatics analysis identifies metabolic and immune-related diagnostic biomarkers shared between diabetes and COPD using multi-omics and machine learning by Qianqian Liang, Yide Wang, Zheng Li, Zheng Li, Zheng Li, Zheng Li

“…Finally, the 4 shared biomarkers were validated in single-cell sequencing data, clinical samples, and animal models, and their expression changes were consistent with the results of bioinformatic analysis.ConclusionsThrough comprehensive bioinformatics analysis, we revealed the potential connection between diabetes and COPD, providing a theoretical basis for exploring the common regulatory genes.…”
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Geological disaster risk assessment based on ecological niche model: A case study of Longhui County, Shaoyang City by Yun ZHANG, Feng ZI, Jiehua GUO, Yunjiang CAO, Jiuling DUAN, Zhigang GUO, Long TANG

“…This study introduces a novel method for the risk assessment of geological disasters in Longhui County and provides a theoretical basis for the government’s risk management strategy.…”
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Mitigation of PFOA/PFOS toxicity in zebrafish (Danio rerio) by oxidative stress modulation and gut microbial metabolism through the use of aquatic probiotic Lactobacillus rhamnosus by Chun Wang, Guanyi Li, Sibao Chen, Ruixuan Li, Mengyan Wang, Xia Wang, Ning Ding, Yingxue Sun

“…These novel findings not only elucidate the mechanism by which L. rhamnosus efficiently reduces PFOS and PFOA toxicity in zebrafish but also provide a theoretical basis and practical recommendations for utilizing probiotics in aquaculture.…”
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Modeling the hydraulic roughness of a movable flatbed in a sand channel while considering the effects of water temperature by Junzheng Liu, Jinliang Zhang, Zhe Huang, Haijue Xu, Yuchuan Bai, Gang Wang

“…Bedload motion on a movable flatbed causes additional energy loss and increases hydraulic roughness. Several theoretical and empirical predictors for characterizing this phenomenon have been proposed, but the accuracy and physical basis of these models should be improved. …”
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Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…<b>Methods:</b> Using a one-pot assembly approach, we prepared a series of nanoparticles composed of poly-L-lysine and hyodeoxycholic acid (PLL-HDCA NPs). Theoretical simulations and experimental studies were combined to optimize their structure and functionality. …”
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Multi-generational adaptation to Solanum nigrum increases reproduction and decreases microbial diversity of Aphis gossypii by Peng Wang, Peng Wang, Yu-Xi Jing, Ya-Jie Ma, Ya-Jie Ma, Dan Wang, Yong-Pan Shan, Hongyan Hu, Changcai Wu, Xian-Peng Song, Xiangliang Ren, Xiangliang Ren, Xiangliang Ren, Yan Ma, Yan Ma, Yan Ma, Xiaoyan Ma, Xiaoyan Ma, Xiaoyan Ma

“…These findings provide a theoretical foundation for the scientific management of A. gossypii and S. nigrum in the fields.…”
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Brain Functional Network in Chronic Asymptomatic Carotid Artery Stenosis and Occlusion: Changes and Compensation by Shihao He, Ziqi Liu, Zongsheng Xu, Ran Duan, Li Yuan, Chu Xiao, Zhe Yi, Rong Wang

“…In this prospective study, 27 patients with CAO, 29 patients with CAS, and 15 healthy controls matched for age, sex, education, handedness, and risk factors underwent neuropsychological testing and resting-state functional magnetic resonance (rs-fMRI) imaging simultaneously; graph theoretical analysis of brain networks was performed to determine the relationship between changes in brain network connectivity and the progression from internal CAS to CAO. …”
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Current status and development trends of deep coalbed methane research in China by Wei JU, Shu TAO, Zhaobiao YANG, Jiayao CHENG, Haiyan SHANG, Weike NING, Chunlong WU

“…The development of deep CBM technologies and their applicability are the key areas to be explored in the future. Deepening theoretical understanding, quantitatively characterizing geological and engineering conditions, and comprehensively analyzing influencing factors are fundamental and crucial for the further rapid development of deep CBM in China. …”
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The Influences of Key Strata Compound Breakage on the Overlying Strata Movement and Strata Pressure Behavior in Fully Mechanized Caving Mining of Shallow and Extremely Thick Seams:... by Junmeng Li, Yanli Huang, Jixiong Zhang, Meng Li, Ming Qiao, Fengwan Wang

“…The research has great significance in providing theoretical guidance and practical experience for predicting and controlling the ground pressure under the similar mining and geological conditions.…”
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Experimental Investigation of Dispersant on Dynamics of Impact of Al₂O₃ Nanofluid Droplet by Dandan Liang, Ruichao Guo, Zichun Sun, Haizhen Zhao, Guohua Qin, Yongxin Zhang

“…This study can provide theoretical basis and specific guidance for experimental characterization of UAVs’ electronic devices based on the mechanism of nanofluid droplet impact on the wall.…”
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Predictive method for poultry carcass visceral dimensions using 3D point cloud and Genetic Algorithm-based wavelet neural network by Zhengwei Zhu, Yan Chen, Lu Cai, Jinzhou Yang, Ke Wen, Jingjing Bao, Zhigang Hu, Dandan Fu

“…The experimental results showed that the model built in this paper based on 3D point cloud and GA-WNN network can accurately predict the size of the viscera of poultry carcasses, thus providing theoretical references for the automated evisceration technology without damaging the viscera.…”
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The stability of soil aggregates in sweet cherry (Prunus avium L.) orchards of different ages and varieties by Muhao Chen, Shu Feng, Jun Wang, Mingyu Gao, Min Liu, Kaibo Wang, Zhou-ping Shangguan, Yongwang Zhang

“…This study can help to improve the scientific theoretical basis for the introduction of sweet cherry planting on the Loess Plateau and the management of soil quality.…”
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Comparative transcriptome analysis reveals potential regulatory mechanisms in response to changes in physiological functions in Oreochromis aureus under salinity stress by Chang Yuan, Kangqi Zhou, Xianhui Pan, Yong Lin, Junqi Qin, Dapeng Wang, Zhong Chen, Xuesong Du, Yin Huang

“…This study enhances our understanding of O. aureus adaptive strategies under salinity stress, while also providing relevant theoretical insights into the domestication of fish under saline conditions and the mechanisms mediating adaptations to saline aquatic environments.…”
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The response of soil microbial community to application of organic amendment to saline land by Peifei Cong, Peifei Cong, Peifei Cong, Pengfei Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang, Zhisheng Huang

“…In addition, after the application of microbial organic fertilizer, RB41, blastococcus and solirubrobacter significantly increased, while Melothermus and Herpetosiphon significantly decreased.DiscussionThis study provides a strong theoretical basis for using microbial organic fertilizers to improve saline-alkali soil.…”
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Dysbiosis of Gastric Mucosal Fungal Microbiota in the Gastric Cancer Microenvironment by Zhenzhan Zhang, Hao Feng, Yaopeng Qiu, Zhou Xu, Qingfeng Xie, Wenfu Ding, Hao Liu, Guoxin Li

“…This study revealed a novel perspective on the role of Solicoccozyma in tumors and a theoretical basis for therapeutic targets against GC.…”
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<i>Weizmannia coagulans</i> BC99 Attenuates Oxidative Stress Induced by Acute Alcoholic Liver Injury via Nrf2/SKN-1 Pathway and Liver Metabolism Regulation by Ying Wu, Cheng Li, Yinyin Gao, Jie Zhang, Yao Dong, Lina Zhao, Yuwan Li, Shaobin Gu

“…Taken together, these findings reveal that BC99 mitigates alcohol-induced oxidative stress by activating the Nrf2/SKN-1 pathway and regulating liver metabolites to eliminate excess ROS, thereby providing a theoretical basis for the application of probiotics in preventing acute alcoholic liver injury.…”
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JWST, ALMA, and Keck Spectroscopic Constraints on the UV Luminosity Functions at z ∼ 7–14: Clumpiness and Compactness of the Brightest Galaxies in the Early Universe by Yuichi Harikane, Akio K. Inoue, Richard S. Ellis, Masami Ouchi, Yurina Nakazato, Naoki Yoshida, Yoshiaki Ono, Fengwu Sun, Riku A. Sato, Giovanni Ferrami, Seiji Fujimoto, Nobunari Kashikawa, Derek J. McLeod, Pablo G. Pérez-González, Marcin Sawicki, Yuma Sugahara, Yi Xu, Satoshi Yamanaka, Adam C. Carnall, Fergus Cullen, James S. Dunlop, Eiichi Egami, Norman Grogin, Yuki Isobe, Anton M. Koekemoer, Nicolas Laporte, Chien-Hsiu Lee, Dan Magee, Hiroshi Matsuo, Yoshiki Matsuoka, Ken Mawatari, Kimihiko Nakajima, Minami Nakane, Yoichi Tamura, Hiroya Umeda, Hiroto Yanagisawa

“…The UV luminosity functions derived from these spectroscopic results are consistent with a double power-law function, showing tensions with theoretical models at the bright end. To understand the origin of the overabundance of bright galaxies, we investigate their morphologies using JWST/NIRCam high-resolution images obtained in various surveys, including PRIMER and COSMOS-Web. …”
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Research note: The critical role of the interaction between Eimeria tenella invasion protein RON2 and host receptor annexin A2 in mediating parasite invasion by Junli Ni, Xiangjie Chen, Yunyun Sun, Yibin Zhu, Haiming Cai, Yongle Song, Minna Lv, Juan Li, Shenquan Liao, Nanshan Qi, Mingfei Sun, Jianfei Zhang, Youfang Gu, Xinchao Liu, Xuhui Lin

“…Understanding the interaction between the EtRON2 protein and its receptor during parasite invasion could help elucidate the function of the EtRON2 receptor and provide a theoretical foundation for further studies on the invasion mechanisms of E. tenella and the prevention and control of avian coccidiosis.…”
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Excessive copper induces lignin biosynthesis in the leaves and roots of two citrus species: Physiological, metabolomic and anatomical aspects by Xin Zhou, Xing Xiong, Fei Lu, Wenqing Shi, Yu Zhou, Ningwei Lai, Li-Song Chen, Zeng-Rong Huang

“…The findings from the present study increased our understanding of lignin biosynthesis in Cu-stressed citrus species, which would provide a theoretical basis for the citrus Cu-tolerant mechanisms.…”
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Inhibition of the invasive plant Ambrosia trifida by Sigesbeckia glabrescens extracts by Lijuan Yin, Guangzhong Zhang, Haoyu Zhao, Yuxin Zhang, Jiaozi Wangchen, Fanghao Wan, Bo Liu, Wanqiang Qian

“…Taken together, the results of this study revealed the mechanism underlying the toxic effects of S. glabrescens on A. trifida, providing a theoretical basis for the use of interspecific plant competition for invasive weed control and further application of S. glabrescens allelochemicals in weed management.…”
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