Caffeine Consumption Influences Lidocaine Action via Pain-Related Voltage-Gated Sodium Channels: An In Vivo Animal Study by Reham Alfaraj, Zainab Alabdulsalam, Zahrah Alfaraj, Hawraa Alsunni, Hussain Alhawaj, Omar Omar, Hatem Abuohashish

“…This synergistic effect was noted at 60 minutes (11 weeks of CAF intake) and at 30 minutes (12 weeks of CAF intake) compared with LIDO alone. …”
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The Implementation of Therapeutic Alliance in the Rehabilitation of an Elite Pediatric Athlete with Salter-Harris Fracture: A Case Report by Lucas VanEtten, Matthew Briggs, John DeWitt, Cody Mansfield, Christopher Kaeding

“…Post-operative care included immobilization in a brace for six weeks and he initiated physical therapy for four weeks (post-op weeks 6-10). …”
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The “Mother Load” and Return to Sport: A Case Report of Returning to Professional Netball Following Cesarean Section by Alexandra Diggles

“…Measures were collected at four weeks, eight weeks, and six months post-partum. The post-partum athlete demonstrated alterations in pelvic floor muscle function, reduced lower limb power and psychological readiness. …”
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Three-dimensional analysis using a dental model scanner: Morphological changes of occlusal appliances used for sleep bruxism under dry and wet conditions. by Aya Ozawa, Yoshitaka Suzuki, Kazuo Okura, Toshinori Okawa, Susumu Abe, Kohei Kamoi, Emi Uyama, Kenichi Hamada, Yoshizo Matuka

“…<h4>Methods</h4>Eight OcAs were prepared using polymethyl methacrylate, stored in water at room temperature for 4 weeks (wet storage), and then in air for 4 weeks (dry storage). …”
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Polycystic ovary syndrome in a patient with type B insulin resistance syndrome can improve with glucocorticoid treatment: a case report and literature review by Tetsuhiro Watanabe, Saori Okabe, Shohei Sakamoto

“…Then, the enlargement of both ovaries diminished at 32 weeks, and the menstruation had normalized since 36 weeks. …”
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Hear me out: an audit of paediatric ventilation tube surgery wait times in patients with recurrent acute otitis media and/or otitis media with effusion at Christchurch Hospital by Analise Yunzhen Wang

“…The median wait time from general practice referral to the day of surgery was 43.3 weeks. Patients were waiting a median time of 9.8 weeks after general practice referral to be seen in clinic and were spending 26.3 weeks on the waitlist for ventilation tube surgery. …”
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Comparative Evaluation of Intra-articular Ozone and Steroid Treatments in Patients with Coxarthrosis under Ultrasound Guidance: A Retrospective Study by Yilmaz Karaduman, Arzu Muz, Azize Serçe, Servi Yildirim, Ismail Eren Durmus, Suna Akin Takmaz

“…Monthly analgesic use was monitored before treatment and at the 1st week, 1st month, 3rd month and 6th month. Statistical analysis were conducted using Unpaired t-tests and Chi-square tests. …”
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Evaluation of a Guided Chatbot Intervention for Young People in Jordan: Feasibility Randomized Controlled Trial by Anne Marijn de Graaff, Rand Habashneh, Sarah Fanatseh, Dharani Keyan, Aemal Akhtar, Adnan Abualhaija, Muhannad Faroun, Ibrahim Said Aqel, Latefa Dardas, Chiara Servili, Mark van Ommeren, Richard Bryant, Kenneth Carswell

“…Online questionnaires were administered at baseline (week 0) and postassessment (week 8) to assess depression (Hopkins Symptom Checklist-25 [HSCL-25]), anxiety (HSCL-25), functional impairment (WHO Disability Assessment Schedule [WHODAS] 2.0), psychological well-being (WHO-Five Well-Being Index [WHO-5]), and agency (State Hope Scale). …”
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Prediction of Preterm Birth by Maternal Characteristics and Medical History in the Brazilian Population by Enio Luis Damaso, Daniel Lober Rolnik, Ricardo de Carvalho Cavalli, Silvana Maria Quintana, Geraldo Duarte, Fabricio da Silva Costa, Alessandra Marcolin

“…Of those, 23 (1.7%) had a spontaneous PTB before 34 weeks of gestation, 87 (6.6%) had a preterm birth between 34 and 37 weeks, and 1,197 (91.7%) had a term delivery. …”
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Advancing Anaesthetist Rostering Quality: A Practical Approach Toward Fairness and Efficiency by Norizal Abdullah, Masri Ayob, Meng Chun Lam, Nasser R. Sabar, Graham Kendall, Liu Chian Yong

“…The model reduced penalties by 69.57% for monthly rosters and 64.37% for weekly rosters compared to manual scheduling. Statistical analysis proved significant enhancement in monthly rosters and weekly rosters. …”
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Correlation Between Objective Habit Metrics and Objective Medication Adherence: Retrospective Study of 15,818 Participants From Clinical Studies by Antoine Pironet, L Alison Phillips, Bernard Vrijens

“…Further, two objective habit metrics were computed from each participant’s medication intake history: (1) SD of the hour of intake, representing daily variability in the timing of medication intakes, and (2) weekly cross-correlation, representing weekly consistency in the timing of medication intakes. …”
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Sleep patterns and smartphone use among left-behind children: a latent class analysis and its association with depressive symptoms by Xue Han, Cheng-Han Li, Heng Miao, Su Xu, Wen-Jing Yan, Juan Chen, Juan Chen

“…Latent class analysis was conducted using weekday and weekend sleep duration and smartphone use as indicators. …”
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A qualitative study exploring the acceptability of the TEXTPAD telehealth and virtual supervised exercise intervention and trial for patients with peripheral arterial disease livin... by Maddey Patterson, MPH, Letitia Sermin-Reed, MSc, James Prentis, MBBS, Arathi Radhakrishnan, MBBS, Eileen Kaner, PhD, Sandip Nandhra, MBBS, Maisie Rowland, BSc, Gabriel Cucato, PhD, Mackenzie Fong, PhD

“…The TEXTPAD pilot randomized controlled trial investigated the impact of the 12-week TEXTPAD intervention that involved weekly phone calls for behavioral counselling and twice-weekly virtual, supervised exercise sessions. …”
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Monitoring Population Phenology of Asian Citrus Psyllid Using Deep Learning by Maria Bibi, Muhammad Kashif Hanif, Muhammad Umer Sarwar, Muhammad Irfan Khan, Shouket Zaman Khan, Casper Shikali Shivachi, Asad Anees

“…In the current study, several prediction models were developed based on regression algorithms of machine learning to monitor different phenological stages of Asian citrus psyllid to predict its population about different abiotic variables (average maximum temperature, average minimum temperature, average weekly temperature, average weekly relative humidity, and average weekly rainfall) and biotic variable (host plant phenological patterns) in citrus-growing regions of Pakistan. …”
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Efficacy and Safety of Sofosbuvir-Based Direct-Acting Antiviral Agents Treatment for Patients with Genotype 3/6 Hepatitis C Virus Infection by Yong-yu Mei, You-ming Chen, Yuan-kai Wu, Xiao-hong Zhang, Wen-xiong Xu

“…The treatment regimens included SOF + RBV for 24 weeks, SOF + DCV ± RBV for 12/24 weeks, and SOF/VEL ± RBV for 12 weeks. …”
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Lack of Tissue Virological Response as a Predictor of Relapse in Chronic Hepatitis D after Completion Bulevirtide Therapy by P. O. Bogomolov, N. A. Shub, N. A. Gasilova, A. A. Belyakova, T. G. Lidzhieva, E. A. Kondrasheva, N. A. Barsukova, M. V. Arapova, E. A. Isaeva, S. V. Koblov, M. V. Kalashnikov, O. S. Kuzymina, A. Yu. Demyanov, A. O. Bueverov, I. V. Maev

“…The study included 21 patients with CHD who received combined AVT with peginterferon alpha and bulevirtide for 48 weeks, followed by bulevirtide monotherapy for 48–96 weeks, making the total duration of antiviral therapy 96–144 weeks. …”
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Cross-species comparisons between pigs and mice reveal conserved sex-specific intraspinal inflammatory responses after spinal cord injury by Reena Kumari, Gabrielle V. Hammers, Robert H. Hammons, Andrew N. Stewart, Steven M. MacLean, Tracy Niedzielko, Lonnie E. Schneider, Candace L. Floyd, John C. Gensel

“…Results SCI caused locomotor dysfunction (measured with the Porcine Thoracic Injury Behavior Score) with some recovery over 6 weeks and limited tissue sparing at 6 weeks with no difference between sexes. …”
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Establishing rabbit critical-size bone defects to evaluate the bone-regeneration potential of porous calcium phosphate ceramics by Wei Lei, Yan Wu, Yan Wu, Hao Yuan, Ping He, Jingqi Wu, Jingrong Chen, Yuxiao Liu, Hongmei Zhang, Joost D. de Bruijn, Xuerong Xiang, Ping Ji, Huipin Yuan, Huipin Yuan, Mingzheng Li

“…Furthermore, the bone area within the available space of BCP implants increased significantly from 19.3% ± 7.3% at 12 weeks to 37.7% ± 8.5% at 24 weeks (p = 0.0063), accompanied by significant BCP resorption (14.8% at 12 weeks and 30.2% at 24 weeks). …”
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International REACH forgiveness intervention: a multisite randomised controlled trial by Tyler J Vanderweele, Nicole Rodriguez, Richard G Cowden, Man Yee Ho, Everett L Worthington, Andrea Ortega Bechara, Zhuo Job Chen, Elly Yuliandari Gunatirin, Shaun Joynt, Viacheslav V Khalanskyi, Hennadii Korzhov, Ni Made Taganing Kurniati, Anastasiya Anastasiya Salnykova, Liudmyla Shtanko, Sergiy Tymchenko, Vitaliy L Voytenko, Anita Zulkaida, Maya B Mathur

“…The analytic sample consisted of n=4598 participants, median age 26 and 73% female.Interventions At each site, participants were randomly assigned to either immediate receipt of a self-directed forgiveness workbook intervention, or to receipt after a 2 week delay.Main outcomes measures The primary outcomes were unforgiveness (Transgression-Related Interpersonal Motivations Inventory-18), depression symptoms, and anxiety symptoms (Brief Symptom Inventory-18) measured at 2 weeks following intervention assignment.Results At 2 weeks follow-up, unforgiveness was lower among the immediate-treatment group compared with the delayed-treatment group (standardised mean difference=−0.53 (95% CI=−0.58 to –0.47)); similar patterns were found for depression (standardised mean difference=−0.22 (95% CI=−0.28 to –0.16)) and anxiety symptoms (standardised mean difference=−0.21 (95% CI=−0.27 to –0.15)).Conclusions A brief workbook intervention promoted forgiveness and reduced depression and anxiety symptoms. …”
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Cinnamic acid alleviates endothelial dysfunction and oxidative stress by targeting PPARδ in obesity and diabetes by Yizhen Bai, Dechao Tan, Qiaowen Deng, Lingchao Miao, Yuehan Wang, Yan Zhou, Yifan Yang, Shengpeng Wang, Chi Teng Vong, Wai San Cheang

“…Methods High-fat diet (HFD) with 60 kcal% fat was used to induce obesity/diabetes in C57BL/6 mice for 12 weeks. These diet-induced obese (DIO) mice were orally administered with CA at 20 or 40 mg/kg/day, pioglitazone (PIO) at 20 mg/kg/day or same volume of vehicle during the last 4 weeks. …”
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