Effect of an Internet-Based Pilates Telerehabilitation Intervention in People With Multiple Sclerosis: Protocol for a Randomized Controlled Trial by Andrea Tacchino, Michela Ponzio, Paolo Confalonieri, Letizia Leocani, Matilde Inglese, Diego Centonze, Eleonora Cocco, Paolo Gallo, Damiano Paolicelli, Marco Rovaris, Loredana Sabattini, Gioacchino Tedeschi, Luca Prosperini, Francesco Patti, Edoardo Sessa, Elisabetta Pedrazzoli, Mario Alberto Battaglia, Giampaolo Brichetto

“…Participants in the MS-FIT group will train at home with MS-FIT for 12 weeks and will be required to perform the exercises for a total of 30 minutes/day for at least 3 days/week. …”
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Beneficial Effect of Multidomain Cognitive Training on the Neuropsychological Performance of Patients with Early-Stage Alzheimer’s Disease by Anastasia Nousia, Vasileios Siokas, Eleni Aretouli, Lambros Messinis, Athina-Maria Aloizou, Maria Martzoukou, Maria Karala, Charalampos Koumpoulis, Grigorios Nasios, Efthimios Dardiotis

“…The duration of the MCT intervention program was 15 weeks, and it was administered twice a week. Each session lasted for approximately one hour. …”
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Exploring the effect of play on heart rate variability as a measure of positive emotional states in pigs by Karolína Steinerová, Annika Krause, Sarah E. Parker, Yolande M. Seddon

“…Play treatment pigs were reared with intermittent play promotion (3x/week) from 10 weeks of age. For HRV recordings, play was promoted for 15-min in pairs of gilts within treatment, with destructible novel objects given either in the home pen (NOV, 1 m2/pig), or in an enclosed ‘playpen’ area providing extra space (PLP, 2.9 m2/ pig). …”
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Effects of melatonin supplementation on oxidative stress, and inflammatory biomarkers in diabetic patients with chronic kidney disease: a double-blind, randomized controlled trial by Sara Sadeghi, Amirahmad Nassiri, Monir Sadat Hakemi, Fatemeh Hosseini, Fatemeh Pourrezagholie, Fatemeh Naeini, Aylar Nadiri Niri, Hossein Imani, Hamed Mohammadi

“…Statistical analysis was performed using SPSS, with significance set at p < 0.05. Results The 10-week trial was completed by 41 participants in total, and no adverse effects were noted. …”
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Maternal singing and speech have beneficial effects on preterm infant’s general movements at term equivalent age and at 3 months: an RCT by Manuela Filippa, Gianluca Filippa, Elisa Della Casa, Alberto Berardi, Odoardo Picciolini, Sara Chiara Meloni, Clara Lunardi, Alessandra Cecchi, Alessandra Sansavini, Luigi Corvaglia, Luigi Corvaglia, Didier Grandjean, EVC Group, Fabrizio Ferrari

“…The aim of this study was to investigate the effects of maternal singing and speaking in the Neonatal Intensive Care Unit (NICU) on preterm infants’ GMs at term equivalent age and at 3 months.MethodsIn this multi-center randomized clinical trial, 56 stable preterm infants (25–32 weeks) were randomized to either an intervention group – in which mothers were asked to speak and sing to their infants for 20 min, 3 times per week, for 2 weeks – or to a control group. …”
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A mobile-based multidomain lifestyle intervention using Cognitive Evergreenland for older adults with subjective cognitive decline: a feasibility study by Rong Lin, Yuanjiao Yan, Zhili Chen, Chenshan Huang, Junyu Zhao, Mingfeng Chen, Hong Li

“…Mean participant age was 70.93 ± 6.91 years, 73.2% of participants were female, and mean Montreal Cognitive Assessment score was 24.51 ± 2.87. Throughout the 24 weeks of the prescribed intervention, app usage remained consistently high, with over 92% of participants using the mini-program at least once a week and successfully completing corresponding health management tasks. …”
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Efficacy of Shenqi Pollen Capsules for High-Altitude Deacclimatization Syndrome via Suppression of the Reoxygenation Injury and Inflammatory Response by Binfeng He, Mingdong Hu, Zhihui Liang, Qianli Ma, Yunhai Zi, Zhiwei Dong, Qi Li, Yongjun Luo, Guisheng Qian, Liang Guo, Kexiong Lin, Zhenyu Liu, Guansong Wang

“…We randomly allocated 20 clusters of subjects (1 : 1) to receive SPCs or a placebo for 7 weeks, and they were then followed up to the 14th week. …”
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Changes in Intestinal Microbiota Are Associated with Islet Function in a Mouse Model of Dietary Vitamin A Deficiency by Yunting Zhou, Junming Zhou, Yumin Zhang, Jun Tang, Bo Sun, Wei Xu, Xiaohang Wang, Yang Chen, Zilin Sun

“…Here, we explored whether and how intestinal microbiota affects glucose homeostasis in VA-deficient diet-fed mice. Methods. Six-week-old male C57BL/6 mice were randomly placed on either a VA-sufficient (VAS) or VA-deficient (VAD) diet for 10 weeks. …”
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Risedronate Attenuates Podocyte Injury in Phosphate Transporter-Overexpressing Rats by Yohei Asada, Takeshi Takayanagi, Tsukasa Kawakami, Eisuke Tomatsu, Atsushi Masuda, Yasumasa Yoshino, Sahoko Sekiguchi-Ueda, Megumi Shibata, Tomihiko Ide, Hajime Niimi, Eishin Yaoita, Yusuke Seino, Yoshihisa Sugimura, Atsushi Suzuki

“…We subcutaneously administered 5 μg/kg body weight of risedronate or saline twice a week during the experimental period. Risedronate did not alter serum creatinine levels at 5, 8, and 12 weeks of age. …”
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Efficacy of Nonpreserved Sodium Hyaluronate Artificial Tears in Dry Eye Disease Patients Treated with Prostaglandin Analogs for Primary Open-Angle Glaucoma: A Prospective, Nonrando... by Giulia Coco, Danilo Iannetta, Igino Febbraro, Ester Elmo, Gianluca Manni

“…Secondary outcomes confirmed the positive results, with a statistically significant change in the OSDI score and CFS between the baseline and 4 (p=0.02 and p<0.001, respectively) or 12 weeks (both p<0.001) and TBUT after 4 weeks (p=0.01). …”
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Clinical Feature of Men Who Benefit from Dose Escalation of Naftopidil for Lower Urinary Tract Symptoms: A Prospective Study by Takaki Mizusawa, Noboru Hara, Kenji Obara, Etsuko Isahaya, Yuki Nakagawa, Kota Takahashi

“…The 75 mg group showed improvement in the total IPSS and QOL score in a dose-dependent manner (at 4 weeks: 𝑃<.001, at 4 weeks versus 8 weeks: 𝑃<.05). …”
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Differentiating the cognitive development of early-term births in infants and toddlers: a cross-sectional study in China by Jing Hua, Jie Sun, Zhijuan Cao, Xiaotian Dai, Senran Lin, Jialin Guo, Guixiong Gu, Wenchong Du

“…Objectives This study aimed to explore the cognitive development of low-risk children during early childhood for early-term births at 37 and 38 weeks of gestation compared with full term births at 39–41 weeks of gestation.Setting and participants We conducted a cross-sectional study in Shanghai, one of the largest cities in China. …”
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Translation of a Diabetes Remission Service into Australian Primary Care: Findings from the Evaluation of DiRECT-Australia by Ritesh Chimoriya, Kimberly Mitlehner, Chee L. Khoo, Uchechukwu Levi Osuagwu, Russell Thomson, Lei Si, Michael Lean, David Simmons, Milan K. Piya

“…Of 39 recruited participants, 32 (82.1%) and 27 (69.2%) completed 12 weeks and 52 weeks of the structured program, respectively. …”
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Umbilical Artery Thrombosis with Associated Acute and Severe Fetal Growth Restriction and Transient Severe Protein S Deficiency: Report of a Case with Prenatal Ultrasound Diagnosis... by Ali Alhousseini, Sunil Jaiman, Edgar Hernandez-Andrade, Salam Zeineddine, Faisal Qureshi, Suzanne M. Jacques

“…A 21-year-old gravida 1 patient, with a history of 3-vessel cord at 20 weeks, presented at 29 weeks with a single umbilical artery. …”
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Effects of Sodium-Glucose Cotransporter-2 Inhibitors on Urine Albumin to Creatinine Ratio in Type 2 Diabetes Mellitus Patients and Medication Care by Dong-Dong Wang, Cun Zhang, Yang Yang, Su-Mei He, Ping Zhu, Xiao Chen

“…The maximal effect (Emax) and the treatment duration of reaching half of Emax (ET50) from SGLT-2 inhibitors on UACR in T2DM patients were -19.2% and 0.448 weeks, respectively. Further, the treatment duration to reach 25%, 50%, 75%, and 80% Emax was 0.150 weeks, 0.448 weeks, 1.344 weeks, and 1.792 weeks, respectively. …”
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Impact of hepatic steatosis on the efficacy of antiviral treatment for chronic hepatitis B and the establishment of predictive model: a cohort study by Guanghui Ren, Kaining Jia, Shi Yin, Yunpeng Guan, Qingwei Cong, Ying Zhu

“…Kaplan–Meier survival analysis revealed a shorter median time to HBsAg response at 48 weeks for the CHB + MASLD group (HR = 3.251, 40 weeks vs. 42.5 weeks, p = 0.002). …”
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Protocol of an open-label safety and feasibility pilot study of ketamine-assisted psychotherapy for methamphetamine use disorder (the KAPPA trial) by Jonathan Brett, Celia Morgan, Nadine Ezard, Brendan Clifford, Krista J Siefried, Robert May, Liam Acheson, Kathryn Fletcher, Harriet MacDonald, Gillinder Bedi, Alexandre Guerin, Elizabeth Knock, Michael Millard, Jess Doumany

“…Safety and feasibility will be assessed over an 8-week period. Secondary outcomes (changes in methamphetamine use, cravings, withdrawal, quality of life and treatment satisfaction) will be assessed over a 24-week period.Ethics and dissemination This study has been approved by the St Vincent’s Hospital Human Research Ethics Committee, reference 2023/ETH00530. …”
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Early temperature records from a Norwegian coastal farm (1880–1930) by Ann Rigmor Nerheim

“…The data are based on diary notes of weekly temperature ranges. Maximum and minimum temperatures have been investigated, as well as weekly, monthly, and yearly average temperatures. …”
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Persistence of Olfactory Dysfunction in Post CoVid-19 Patients Using Sniffin Sticks-A Prospective Study by Priyanka Thangaraj, Sowmya Gajapathy, Jayita Das Poduval

“…RESULTS Total 40 eligible patients were selected. 50% of study participants were males and 60% aged 18-38 years. 3 patients were Diabetic and 3 were Hypertensive. 37 had OD of which 26 had Hyposmia and 11 had Anosmia 6 weeks Post CoVid. 22 had OD of which 14 had Hyposmia and 8 had Anosmia 10 weeks Post CoVid. 10 had persistent OD 12 weeks Post CoVid. …”
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Allium Cepa (Onion) Extract Enhances and Protects Testicular Function and Architecture against Paraquat Induced Oxidative Damage. by Uzozie Chikere, Ofoego, Ejike, Daniel Eze

“…Group A (Control) received feed and water; test groups (B-F) were treated orally as follows: group B (20 mg/kg b.w. of paraquat for 4weeks); group C (1000 mg/kg b.w. of A. cepa extract for 4weeks); group D (a co-administration of 20 mg/kg b.w. of paraquat and 100 mg/kg b.w. of A. cepa extract for 4weeks); group E (a co-administration of 20 mg/kg b.w. of paraquat and 1000 mg/kg b.w. of A. cepa extract for 4weeks); and group F (1000 mg/kg b.w. of A. cepa extract for 2weeks before co-administration with 20 mg/kg b.w. of paraquat for 2weeks). …”
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