The Effects of Parathyroid Hormone Applied at Different Regimes on the Trochanteric Region of the Femur in Ovariectomized Rat Model of Osteoporosis by M. Tezval, A. Banhardt, S. Sehmisch, L. Kolios, U. Schmelz, K. M. Stuermer, E. K. Stuermer

“…Three groups were ovariectomized, and 8 weeks later they were administered the following treatments (5 weeks): soy-free diet (OVX), subcutaneously injected PTH (0.040 mg/kg) 5 days a week (PTH 5x/w), subcutaneously injected PTH (0.040 mg/kg) every 2 days (PTH e2d), and a sham group. …”
Get full text

Evaluation of coloring therapy as an anxiety reduction strategy in the older adults in the community area by Putri Noor Rochmah Ida Ayu Trisno, Cahyaningrum Etika Dewi, Wurdaningsih Tri Kusuma, Syangadah Zulfiati, Mesayu Salma Fadzila

“…Participants’ anxiety was measured using the Geriatric Anxiety Scale (GAS), which consists of 25 items, before and after four weeks of intervention. The art therapy intervention was conducted in two sessions per week for four weeks, totaling eight sessions. …”
Get full text

In vivo antidiabetic and ex-vivo antioxidant activities of dichloromethane extract of Xerophyta spekei by Michael Musila Ndile, Wycliffe Arika Makori, Cromwell Mwiti Kibiti, Mathew Piero Ngugi

“…Thereafter, the blood glucose in mice was determined once a week for three weeks. During the experimental period of three weeks, body weights were determined. …”
Get full text

Impact of Endurance Exercise Training on Biomarkers of Aortic Endothelial Damage in Diabetic Rats by Mahtab Fouladi, Maryam Mahmoudabady, Zahra Gholamnezhad, Sadegh Shabab, Saeed Niazmand, Hossein Salmani

“…Diabetic rats underwent either interval training or continuous training (40 min/day, 5 days/week, 6 weeks), received metformin (300 mg/kg), or a combination of metformin and exercise. …”
Get full text

Rationale and design of Diabetes Prevention with active Vitamin D (DPVD): a randomised, double-blind, placebo-controlled study by Yoshiya Tanaka, Yosuke Okada, Tetsuya Kawahara, Gen Suzuki, Tetsuya Inazu, Shoichi Mizuno, Fumiyoshi Kasagi

“…Secondary endpoint is the number of participants who achieve normoglycaemia at 48, 96 and 144 weeks. Follow-up is estimated to span 144 weeks.Ethics and dissemination All protocols and an informed consent form comply with the Ethics Guideline for Clinical Research (Japan Ministry of Health, Labour and Welfare). …”
Get full text

Therapeutic Effects of Tangshen Formula on Diabetic Nephropathy in db/db Mice Using Cytokine Antibody Array by Xue Mei Fan, Chun Lian Huang, Yi Ming Wang, Ning Li, Qiong Lin Liang, Guo An Luo

“…The treated groups were orally administered with TSF and losartan for 12 weeks. Biochemical and histological examinations were determined at 8 and 12 weeks posttreatment, while the cytokine antibody array analysis was applied to analyze the expression of 144 cytokines in kidney tissues at the end of the 12th week posttreatment. …”
Get full text

Patient-reported outcome improvements following scalp hair regrowth among patients with Alopecia Areata: analysis of the ALLEGRO-2b/3 trial by Ernest H. Law, Kent A. Hanson, Matthew Harries, Dane Korver, Bintu Sherif, Costel Chirila

“…Responders were defined by a Week 24 Severity of Alopecia Tool (SALT) score ≤20 (SALT20) or ≤10 (SALT10). …”
Get full text

Effects of ruminal short-chain fatty acid concentration and pH on histology, hematology, and inflammation in cannulated Holstein dairy calves by A.R. Wolfe, M.H.P.M. Narciso, R.R.E. Uwiera, A.H. Laarman

“…Holstein calves (n = 32) had the rumen cannulated within the first week of life and at wk 2 were blocked by BW and randomly assigned in a 2 × 2 factorial arrangement of treatments. …”
Get full text

Identification of serum metabolite biomarkers in premature infants with bronchopulmonary dysplasia: protocol for a multicentre prospective observational cohort study by Ping Zhou, Jun Chen, Ying Liu, Cheng Chen, Xin Guo, Zhangbin Yu, Jiebo Liu, Yanping Guo, Dan Dan Rao, Shengnan He, Xudong Yan, Wanxiang He, Songzhou Xu, Ruolin Zhang

“…Serum samples will be collected at five distinct time points: within 24 hours after birth, at 1 week, 2 weeks, 28 days and at 36 weeks postmenstrual age. …”
Get full text

Effectiveness of a Web-Based Self-Guided Intervention (MINDxYOU) for Reducing Stress and Promoting Mental Health Among Health Professionals: Results From a Stepped-Wedge Cluster Ra... by Yolanda López-del-Hoyo, Selene Fernández-Martínez, Adrian Perez-Aranda, Alicia Monreal-Bartolomé, Alberto Barceló-Soler, Loreto Camarero-Grados, Carilene Armas-Landaeta, José Guzmán-Parra, Vera Carbonell, Daniel Campos, Xinyuan Chen, Javier García-Campayo

“…They were divided into 6 clusters—3 per region—and randomly assigned to 1 of the 3 sequences, each starting with a control phase and then transitioning to the intervention phase (the MINDxYOU program) after 8, 16, or 24 weeks. This self-guided, web-based program, designed to be completed over 8 weeks, included weekly contact (via WhatsApp, call, or email) from the research team to promote adherence. …”
Get full text

Impact of Flexor Tendon Traction Tenolysis on Clinical Outcomes in Open A1 Pulley Release for Trigger Finger by Shalimar Abdullah, BMBS, MS, Syed Jeffrey Syed Ahmad Kabeer, MBChB, MD, Lim Chia Hua, MD, Jamari Sapuan, MD, MS, Parminder Singh Gill, MBBS, MS, Elaine Soh Zi Fan, MBBS, MD

“…Postoperative assessments were conducted at 2 weeks, 2 months, and 4 months, documenting finger range of motion, QuickDASH scores, complications, and surgery duration. …”
Get full text

The Effects of Exercise on Inhibitory Function Interventions for Patients With Major Depressive Disorder (MDD): A Systematic Review and Meta‐Analysis by Zhihui Xu, Cong Liu, Peng Wang, Xing Wang, Yuzhang Li

“…Our study found that other types of exercise (RE or ME), intervention duration of >45 min, intervention period of ≤12 weeks, frequency of two times per week, and low intensity are more effective for improving inhibitory function in MDD patients. …”
Get full text

Intermittent Fasting Protects Against the Progression from Acute Kidney Injury to Chronic Kidney Disease by Yoonjoo Jang, Young Suk Kim, Seo Rin Kim, Dong Won Lee, Soo Bong Lee, Il Young Kim

“…Using a unilateral ischemia-reperfusion injury (UIRI) model in male C57BL/6 mice, we evaluated the impact of IF on tubulointerstitial fibrosis and tubular epithelial–mesenchymal transition (EMT) over 8 weeks. Mice in the IF group followed a 5:2 regimen, fasting for 24 h twice weekly. …”
Get full text

Cetuximab Plus Methotrexate in Recurrent and/or Metastatic Head-and-Neck Squamous Cell Carcinoma by Wen-Chen Tang, Pei-Wei Huang, Chien-Yu Lin, Chia-Hsun Hsieh, Cheng-Lung Hsu, Shiang-Fu Huang, Chun-Ta Liao, Chih-Hua Yeh, Nai-Ming Cheng, Hung-Ming Wang*

“…Materials and Methods: A retrospective analysis of patients with RM-HNSCC who received 50 mg MTX weekly plus a standard dose of CTX for a maximum of 18 weeks, without maintenance CTX. …”
Get full text

Contribution of epidermal growth factor (EGF) in the treatment of cutaneous leishmaniasis caused by Leishmania major in BALB/c mice. by Mohammad Saberi, Alireza Latifi, Majid Golkar, Pezhman Fard-Esfahani, Sina Mohtasebi, Aref Teimouri, Mohammad Javad Abbaszadeh Afshar, Elham Kazemirad, Mehdi Mohebali, Mehdi Mohebali

“…The treatment was continued for five weeks, and lesion sizes were measured weekly. Parasite load was determined in the skin biopsies using qPCR. …”
Get full text

Acceptance and commitment therapy reduces perceived ostracism in suicidal patients by Emilie Olié, Manon Malestroit, Véronique Brand-Arpon, Philippe Courtet, Deborah Ducasse

“…Methods This randomized controlled trial included 32 patients with a history of suicide attempt in the past year who followed seven weekly sessions of ACT or progressive relaxation therapy (PRT). …”
Get full text

Effects of group music sessions on cognitive and psychological functions in healthy older adults by Takamitsu Shinada, Michio Takahashi, Akari Uno, Keishi Soga, Yasuyuki Taki, Yasuyuki Taki

“…The intervention group received in weekly 90-minute sessions with the instrument for 16 weeks. …”
Get full text

Efficacy of Cabbage Leaf versus Cooling Gel Pad or Diclofenac Gel for Patients with Knee Osteoarthritis: A Randomized Open-Labeled Controlled Clinical Trial by Thanapon Chobpenthai, Patcharapol Arunwatthanangkul, Wiriya Mahikul

“…All trial participants were trained to record their Numerical Rating Scale (NRS) pain score and Oxford Knee Score and were advised to undergo weekly follow-ups and assessment of the outcome at 4 weeks. …”
Get full text

Preliminary results about the use of injected Lysozime (LIZOVET) to improve the response to synchronization protocol for insemination in buffalo heifers by Francisco Javier Vargas Ortiz, Johnny Ronnel Bracho Ylarraza

“…Additionally, a treatment group (n=10) received treatment with injectable Lysozyme at a dose of 1 cc/60 Kg of intramuscular weight weekly for three weeks. The other heifers were not treated and were left as a control group (n=10). …”
Get full text

Impacts of Selective Predation on Infection Prevalence and Host Susceptibility by Stephanie O. Gutierrez, Ximena E. Bernal, Catherine L. Searle

“…After 6 weeks of selective predation pressure, we found no differences in host abundance or infection prevalence across predation treatments. …”
Get full text