Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial by Basharat Hussain, Basharat Hussain, Muhammad Tahir Khalily, Muhammad Tahir Khalily, Ahmed Waqas, Atif Rahman, Ioannis Angelakis, Anum Nisar, Sabir Zaman, Tanveer Akhtar

“…The intervention’s effectiveness and participant satisfaction were assessed using a variety of measures, including the GHQ-12, WHODAS 2.0, DASS-21, and the Client Satisfaction Questionnaire, at baseline, the 8th week, and during a 3-month follow-up. Qualitative feedback was gathered at the end of the study to assess the intervention’s acceptability among the participants.ResultsThe study achieved a 100% retention rate. …”
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Premorbid predictors of death at initial presentation of coronary heart disease in the Women's Health Initiative study by Ming-Li Chen, Jin Li, Kruthika R. Iyer, Catherine Tcheandjieu, Shirin Jimenez, Elias Levy Itshak Salfati, Liana C. Del Gobbo, Marcia L Stefanick, Manisha Desai, Xiaonan Xue, Themistocles L Assimes

“…A high level of recreational physical activity (>1200 metabolic equivalent (MET) minutes per week) reduced one's relative risk by 32 % (12 to 49 %). …”
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Comparative study of mouse models of atopic dermatitis by Siqi Ye, Lian Zhu, Tao Ruan, Jinjing Jia, Xiumei Mo, Fenggen Yan, Junfeng Liu, Yu Zhang, Dacan Chen

“…BALB/c mice (45.3 %) were the most commonly used. Generally, 4–8-week-old mice were used, and 44 irritants were identified. …”
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Peptide-based vaccine targeting IL17A attenuates experimental spondyloarthritis in HLA-B27 transgenic rats by Tetsuya Tomita, Hiromi Rakugi, Hiroki Hayashi, Ryuichi Morishita, Jiao Sun, Yuka Yanagida, Shota Yoshida, Satoshi Baba, Akiko Tenma, Masayoshi Toyoura, Sotaro Kawabata, Takako Ehara, Ryoko Asaki, Makoto Sakaguchi, Hideki Tomioka, Munehisa Shimamura, Hironori Nakagami

“…The IL17A antibody titre was assessed using ELISA, and arthritis score and joint thickness were monitored two times a week. Enzyme-linked immunospot (ELISpot) assays for IL4- and interferon-γ-secreting splenocytes were conducted to evaluate IL17A-specific T cell activation. …”
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K-nearest neighbor algorithm for imputing missing longitudinal prenatal alcohol data by Ayesha Sania, Ayesha Sania, Nicolò Pini, Nicolò Pini, Morgan E. Nelson, Michael M. Myers, Michael M. Myers, Lauren C. Shuffrey, Maristella Lucchini, Maristella Lucchini, Amy J. Elliott, Amy J. Elliott, Hein J. Odendaal, William P. Fifer, William P. Fifer

“…Using the k-NN imputed values were weighted for the distances and matched for the day of the week. Since participants with no missing days were not comparable to those with missing data, segments of non-missing data from all participants were included as a reference. …”
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Associations of meteorological factors and ambient air pollutants with mumps incidence in Ningxia Hui Autonomous Region: boosted regression tree model analysis by Xianglong LIU, Linlin CHEN, Jiayu YU, Rui GONG, Yaogeng CHEN, Yu ZHAO

“…The BRT model validation results showed that the model had the largest area under the receiver operating characteristic curve (AUC) value of 0.915 for the training set and 0.717 for the test set at a lag of 7 days, with a standard error of 0.027, indicating that in the region, meteorological factors and air pollutants one week prior had the greatest explanatory power for changes in the number of new mumps cases. …”
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Older adults’ Internet use behavior and its association with accelerometer-derived physical activity by Yen-Yu Chung, Jiaren Chen, Mei-Chun Lin, Ruo-Lan Liu, Jenn-Bang Wu, Hsin-Chang Tsai, Ting-Fu Lai, Ting-Fu Lai, Yung Liao, Yung Liao, Jong-Hwan Park, Jong-Hwan Park, Jong-Hwan Park

“…., those who used the Internet less than once a week or not at all, respectively) were less likely to meet the WHO’s recommended levels for PA than older adults who used the Internet with moderate frequency. …”
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Effect of visceral fat area on prognosis of patients undergoing radical gastrectomy and construction of nomogram by Zhicheng Huang, Baohua Zheng, Zhiwei Wang, Xiaobin Chen, Yu Wang

“…We collected the CT image data and clinicopathological data one week prior to the operation and then used software to calculate the VFA, dividing it into two groups: a low VFA group (n = 71) and a high VFA group (n = 85). …”
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Most prevalent jobs of doctoral degree graduates by detailed field of study by Marc Frenette, Tomasz Handler

“…Only individuals who worked during the census reference week (May 2 to 8, 2021) and who completed a Canadian doctoral degree program are included. …”
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Effects of Different Types of Cognitive Training on Cognitive Function, Brain Structure, and Driving Safety in Senior Daily Drivers: A Pilot Study by Takayuki Nozawa, Yasuyuki Taki, Akitake Kanno, Yoritaka Akimoto, Mizuki Ihara, Ryoichi Yokoyama, Yuka Kotozaki, Rui Nouchi, Atsushi Sekiguchi, Hikaru Takeuchi, Carlos Makoto Miyauchi, Takeshi Ogawa, Takakuni Goto, Takashi Sunda, Toshiyuki Shimizu, Eiji Tozuka, Satoru Hirose, Tatsuyoshi Nanbu, Ryuta Kawashima

“…Before and after the 8-week training period, they underwent neuropsychological tests, structural brain magnetic resonance imaging, and driving safety tests. …”
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SHoes for Adolescent PatEllofemoral pain: study protocol for the SHAPE Australian community-based, randomised clinical trial by Kim L Bennell, Kade L Paterson, Rana S Hinman, Jo-Anne Manski-Nankervis, Adam Bryant, Karen Elaine Lamb, Peixuan Li, Sam Shearer, Anurika P De Silva

“…The primary outcomes are the 3-month change in (1) severity of the worst knee pain experienced over the past week, measured using a Numerical Rating Scale, and (2) the function in sport and play subscale of the Knee Injury and Osteoarthritis Outcome Score for Children. …”
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Psychometric properties and meaningful change thresholds for the QOL-E instrument in patients with myelodysplastic neoplasms by Esther Natalie Oliva, Shien Guo, Jennifer Lord-Bessen, Aylin Yucel, Roberto Latagliata, Massimo Breccia, Giuseppe A. Palumbo, Grazia Sanpaolo, Marta Riva, Valeria Santini, Uwe Platzbecker, Guillermo Garcia-Manero, Pierre Fenaux, Christopher G. Pelligra

“…The QOL-E domains/summary scores, except for QOL-SEX, had an adequate ability to detect change from baseline to Week 24. MWPC thresholds were proposed for all other domains and summary scores.ConclusionThe study results demonstrate that the QOL-E is generally fit for purpose to assess treatment effects in populations with LR-MDS and the proposed MWPC thresholds can be used to assess within-patient treatment effect on PROs, as assessed by the QOL-E, in future studies.…”
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Radiotherapy(R) Integration(I) Strategy for Small(S)-Cell Lung Cancer in Extensive(E) Stage (RISE) with up to 10 metastases- a study protocol of a randomized phase II trial by Łukasz Kuncman, Jacek Fijuth, Damian Tworek, Ewa Sierko, Paweł Cisek, Michał Masłowski, Maja Lisik-Habib, Magdalena Orzechowska, Katarzyna Galwas-Kliber, Adam Antczak, Izabela Chmielewska, Barbara Ziółkowska, Marta Kurczewska-Michalak, Wojciech Kuźnicki, Nina Jędrzejczak, Kinga Ranoszek, Mateusz Bilski

“…Blood samples for circulating tumor DNA (ctDNA) will be collected before RT, during each week of treatment, and at the time of disease progression. …”
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Cucumeropsis mannii seed oil shields against cyclophosphamide-induced hepatorenal toxicity by modulating redox imbalance and iNOS/IL-β1 signalling in rats by Amaka Cecilia Agbara, Ejike Daniel Eze, Christian Emeka Offor, Adam Moyosore Afodun, Ezebuilo Ugbala Ekpono, Peter Chinedu Agu, Chinyere Aloke, Nkeiru Nwaamaka Ezeani, Emmanuel Orire Ikuomola, Ekom Monday Etukudo, Ilemobayo Victor Fasogbon, Angela Mumbua Musyoka, Patrick Maduabuchi Aja

“…We measured the body weights of the experimental rats every week. Rats of all groups were sacrificed on day 30 and collected blood for biochemical analysis using standard methods. …”
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Chain-mediated effect of physical activity between Chinese language-based L2 motivational self-system and intended effort by Zixia Bu, Yu Liu, Yi Ba, Shan Jiang, Huijuan Liu, Jiyuan Li, Fuqiang Dong, Haohan Yu, Xindi Zhao

“…According to the SEM test, in addition to the direct effect of L2MSS on intended effort, the following paths existed: (1) ILS→PA→IE (effect=-0.265, ratio = 31.28%, 95%CI=[0.124, 0.527]), (2) OLS→PA→IE (effect = 0.179, ratio = 17.94%, 95%CI=[0.074, 0.256]), (3) ILS→PA→LE→IE (effect = 0.116, ratio = 10.69%, 95%CI=[0.042, 0.248]), (4) OLS→PA→LE→IE (effect = 0.108, ratio = 4.15%, 95%CI=[0.039, 0.126]). total indirect effect为0.304 (ratio = 59.61%, 95%CI=[0.069, 0.289]). (1) PA had an ameliorative effect on L2MSS, learning experience, and intended effort, and increasing PA level increased the significance of this effect. (2) PA level positively predicts L2MSS, learning experience, and intended effort. (3) PA is an important mediator in the process of L2MSS that influences the learning experience and intended effort, so MPA at least 3 days a week can increase the efficiency of second language learning. …”
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Effects of Tributyrin Supplementation on Growth Performance, Intestinal Digestive Enzyme Activity, Antioxidant Capacity, and Inflammation-Related Gene Expression of Large Yellow Cr... by Xiuneng Wang, Min Wan, Zhen Wang, Haitao Zhang, Si Zhu, Xiufei Cao, Ning Xu, Jichang Zheng, Xianyong Bu, Wei Xu, Kangsen Mai, Qinghui Ai

“…An 8-week growth experiment was conducted to investigate effects of tributyrin (TB) supplementation on growth performance, intestinal digestive enzyme activity, antioxidant capacity, and inflammation-related gene expression of juvenile large yellow croaker (Larimichthys crocea) (initial weight of 12.90±0.02 g) fed diets with high level of Clostridium autoethanogenum protein (CAP). …”
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Iterative delivery of an implementation support package to increase and sustain the routine provision of antenatal care addressing alcohol consumption during pregnancy: study proto... by John Attia, Luke Wolfenden, Nicole Nathan, Melanie Kingsland, Olivia Wynne, Penny Reeves, Alix Hall, John Wiggers, Elizabeth J Elliott, Tameka McFadyen, Tracey W Tsang, Emma Doherty, Belinda Tully, Adrian John Dunlop, Ian Symonds

“…Measurement of outcomes will occur via surveys with women who attend antenatal appointments each week. Primary outcomes will be the proportion of women who report being asked about alcohol consumption at subsequent antenatal appointments; and receiving complete care (advice and referral) relative to alcohol risk at initial and subsequent antenatal appointments. …”
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Interaction of dietary replacements of fishmeal by protein blend and feeding frequency on growth performance and protein utilization of gibel carp (Carassius gibelio var. CAS V) by Yongning Yu, Yu Wang, Junyan Jin, Dong Han, Xiaoming Zhu, Haokun Liu, Zhimin Zhang, Yunxia Yang, Shouqi Xie

“…The dietary fishmeal was totally substituted with three protein blends consisting of Tenebrio molitor meal, Chlorella meal, Clostridium autoethanogenum protein, cottonseed protein concentrate, at ratios of 1:1:8:2, 1:1:6:4, and 1:1:4:6, respectively. During an 8-week feeding trial, a total of 960 healthy fish (18.10 g) were randomly assigned to eight groups, each with three replicates. …”
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Assessment of Lower Limb Muscle Volume Using 3D Ultrasonography: Validity and Reliability Compared to MRI by Paul Ritsche, Romina Ledergerber, Michele Pansini, Francesco Santini, Oliver Faude

“…The protocol included two 3DUS sessions and one MRI session spaced one week apart. The 3DUS scans were acquired by one experienced operator, while two operators analyzed the captured volumes from the second scanning timepoint. …”
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Discovery of the microbiota-gut-brain axis mechanisms of acupuncture for amnestic mild cognitive impairment based on multi-omics analyses: A pilot study by Zi-Han Yin, Qiong-Nan Bao, Ya-Qin Li, Yi-Wei Liu, Zi-Qi Wang, Fang Ye, Xia He, Xin-Yue Zhang, Wan-Qi Zhong, Ke-Xin Wu, Jin Yao, Zi-Wen Chen, Ling Zhao, Fan-Rong Liang

“…Results: Compared to a mean baseline to week 12 change of –3.94 in the acupuncture group, the mean change in the waitlist group was 1.72 (net difference, –5.66 [95 % CI, –6.98 to –4.35]). …”
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