Effects of coal mine dust on lung function in rats by LIU Yang, LI Meng, LU Liyuan, WANG Ru, YANG He, ZHANG Huifang

“…Methods: Seventy-two SPF-grade 8-week-old male Sprague-Dawley rats were randomly divided into the coal dust group, the coal-silica dust group, the silica dust group and the control group. …”
Get full text

The use of veno-arterial extra corporeal membrane oxygenation for hemodynamics support during high-risk percutaneous coronary intervention by Wael Samy, Helmy Elghawaby, Akram Abdelbary, Hany Zakaria Mohamed, Alia Hassan Abdel Fattah

“…Also our study showed no statistically difference between LV EF before and after PCI in both groups; in group 1, eight patients had complete revascularization in one session while in group 2 only seven patients had complete revascularization; one patient in group 1 had VT while in group 2, one patient had VF and another one suffered of asystole; group 1 patients all discharged home within 1 week while group 2 had two mortalities during PCI. …”
Get full text

Helicobacter pylori CagA+ strains modulate colorectal pathology by regulating intestinal flora by Shasha Cui, Xinqiang Liu, Fengxia Han, Lu Zhang, Jingjing Bu, Sainan Wu, Jiafen Wang

“…Abstract Aim This article aims to investigate the role of Helicobacter Pylori (HP) CagA+ strains affected colorectal lesion via gut microbiota. Method 6-week C57BL/6J mice were divided into: (a) HP CagA+ group undergoing HP CagA+ strains administration by gavage at 0.2 mL for 10 days; (b) HP CagA- group undergoing HP CagA- strains administration by gavage at 0.2 mL for 10 days; (c) control group intragastrically given 0.2 mL of brian heart infusion (BHI) medium for 10 days. …”
Get full text

Oral Immunisation With Non‐GMO Surface Displayed SARS‐CoV‐2 Spike Epitopes on Bacteria‐Like Particles Provokes Robust Humoral and Cellular Immune Responses, and Modulated the Gut M... by Robie Vasquez, Ji Hoon Song, Remilyn M. Mendoza, In‐Chan Hwang, Bernadette B. Bagon, Lars Engstrand, Valerie Diane Valeriano, Dae‐Kyung Kang

“…Moreover, we examined the influence of oral immunisation on the gut microbiome and microbiota metabolites. Twenty‐eight 6‐week‐old male C57BL/6 mice were orally immunised with the following: PBS (control), Lm. fermentum‐derived BLPs only, BLPs displaying SARS‐CoV‐2 spike S1‐2, or BLPs displaying SARS‐CoV‐2 spike S1‐3 epitopes. …”
Get full text

Protocol for the development of a reporting guideline for causal and counterfactual prediction models in biomedicine by Yi Guo, Hua Xu, Fei Wang, Jie Xu, Jiang Bian, Robert Lucero, Mattia Prosperi

“…Stage 1 will be meetings of a working group every other week with rotating external advisors (active until stage 5). …”
Get full text

Combined effect of exercise and curcumin on inflammation-associated microRNAs and cytokines in old male rats: A promising approach against inflammaging by Zahra Shargh, Keyvan Asghari, Morteza Asghariehahari, Leila Chodari

“…Methods: The study involved 35 male Wistar rats, including 7 young rats (3-month-old; 200–250 g) in the Young control group and 28 aged rats (18-month-old; 400–450 g) randomly distributed among the Old control, Exercise, Curcumin, and Exercise + Curcumin groups. During an 8-week period, the Exercise group underwent running on the treadmill (17 m/min), while those in the Curcumin group were supplied with daily curcumin doses (50 mg/kg) through gavage. …”
Get full text

Benefits of the Global Integration Method (Método de Integração Global - MIG) in functional priorities of parents of Brazilian children and adolescents with autism spectrum disorde... by Amanda Aparecida Alves Cunha Nascimento, Deisiane Oliveira Souto, Thalita Karla Flores Cruz, Arthur Felipe Barroso de Lima, Gabriela Silva Oliveira, Vitor Geraldi Haase

“…The MIG protocol consisted of functional task training in a naturalistic environment (City of Tomorrow) combined with the use of a flexible therapeutic suit (MIG Flex) and was conducted for 3 months, five times a week, for 3–4 h per day. Descriptive statistics were used to provide the priority profile. …”
Get full text

Comparative study of Baduanjin and brisk walking on balance and stability in older adults by Ya-Guang Yu, Jun Zhang, Lin Wang, Dai-Feng Yu, Gong-Bing Shan, Xiao Fu

“…The first two groups participated in a 16-week exercise regimen. The balance tests for members of all three groups were conducted. …”
Get full text

Association between intraoperative fluid management and postoperative outcomes in living kidney donors: a retrospective cohort study by Ja Eun Lee, Chisong Chung, Sunghae Park, Kyo Won Lee, Gaab Soo Kim

“…Twofold increase in sCr (equivalent to stage 2 AKI) during the first week and prolonged hospitalization were most frequent in group 1 [7.8 vs. 1.1 vs. 1.5%, P = 0.004; 7.9 vs. 3.1 vs. 0.7%, P = 0.003]. …”
Get full text

Exploring effects of a booster workshop on progression and retention of resuscitation skills of residents when added to regular low-dose simulation by Hui-Wen Chen, Hung-Wei Tsai, Yi-Chun Chen, Yu-Jui Chiu, Enoch Yi-No Kang, Yi-Ting Hsu, S. Barry Issenberg, Jen-Chieh Wu

“…Residents were divided into two groups: the control group received regular low-dose simulation with faculty-led debriefing at the 1st, 6th, and 11th months, while the intervention group participated in an additional 3-hour simulation workshop one week before the 6th-month scenario. The workshop focused on resuscitation and teamwork skills. …”
Get full text

Blood-based biomarkers suggest prolonged axonal Injury following pediatric mild traumatic brain injury by Andrew R. Mayer, Tracey V. Wick, Jessica R. McQuaid, Masen L. Boucher, Andrew B. Dodd, Cidney R. Robertson-Benta, Harm J. van der Horn, Erik B. Erhardt, Robert E. Sapien, Rawan Tarawneh, Rebekah Mannix

“…Preliminary findings highlight dynamic fluctuations in blood-based biomarkers in the first week of pmTBI, with ongoing evidence of protein release (NFL) at 4 months. …”
Get full text

Interventions to improve media coverage of medical research: a codesigned feasibility and acceptability study with Australian journalists by Brooke Nickel, Ray Moynihan, Alexandra Barratt, Kirsten J McCaffery, Loai Albarqouni, Tessa Copp, Thomas Dakin, Liam Mannix

“…Qualitative data were thematically analysed.Results All participants completed preworkshop and postworkshop questionnaires, and 6 completed the 6-week follow-up (75% retention). Feasibility findings suggest the intervention is acceptable and relevant to journalists, with participants indicating the workshop increased confidence with reporting on medical research. …”
Get full text

Effects of Aerobic Exercise on Rats with Hyperandrogenic Polycystic Ovarian Syndrome by Na Li, Chenghao Yang, Huiyu Xie, Yinghong Liu, Yuanpeng Liao

“…The EC and PE groups underwent a Masashi swimming protocol (120 min per session, 6 days/week, for 15 days). Results indicated that the concentrations of leptin (LP) in the EC group were significantly lower than those in the NC group (p<0.05). …”
Get full text

HuoXueTongFu Formula Alleviates Intraperitoneal Adhesion by Regulating Macrophage Polarization and the SOCS/JAK2/STAT/PPAR-γ Signalling Pathway by Min Zhao, Yao-Yao Bian, Li-Li Yang, Yan-Qi Chen, Ya-Jie Wang, Yan-Ting Ma, Yu-Qiong Pei, Wen-Lin Li, Li Zeng

“…In this study, the model of Intrapetitoneal adhesion was established by cecum abrasion and treated with HXTF for one week. RAW264.7 cells were given LPS, IFN-γ, IL-4, HXTF-medicated serum, and PPAR-γ agonist/antagonist, respectively. …”
Get full text

Adherence to Mediterranean-Like Dietary Pattern in Association with Gastroesophageal Reflux Disease in Adolescents by Azam AhmadiVasmehjani, Sara Beigrezaei, Zahra Nafei, Nasrin Behniafard, Zahra Darabi, Amin Salehi-Abargouei, Majid Aflatoonian

“…GERD symp­toms and the frequency of their occurrence over the last week were assessed using a validated GERD questionnaire. …”
Get full text

Transient sex-related changes in the mice hypothalamo–pituitary–adrenal (HPA) axis during the acute phase of the inflammatory process by T. Daneva, E. Spinedi, R. Hadid, M.-C. Jacquier, M. Giacomini, R. C. Gaillard

“…The potential role of endogenous sex hormones in regulating hypothalamo–pituitary–adrenal (HPA) axis function was investigated after a single injection of endotoxin in adult (8 week old) BALB/c mice of both sexes. The effect of LPS on plasma ACTH, corticosterone (B), testosterone and oestradiol (E) levels and on anterior pituitary (AP) ACTH and adrenal B contents at different times after treatment was studied. …”
Get full text

Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…<h4>Results</h4>Overall, 181 patients were screened and 75 enrolled with 80% 6-week, 82.7% 3-month and 84% 6-month follow-up rates showing appropriate Reach and retention. …”
Get full text

“Inclisiran: Early LDL-C target achievement in a real-life population” by Francesco Briani, Mauro Bagli, Gabriele Venturi, Francesco Bacchion, Antonio Mugnolo

“…Blood samples were collected before the inclisiran administration and at week and one month afterward with the aim toevaluate achievement of LDL-C targets at these time intervals (primary endpoint) and reduction in LDL-C levels (secondary endpoint). …”
Get full text

Endoscopy-assisted anterior cervical discectomy and fusion with internal fixation vs conventional surgery in the treatment of cervical disc herniation by Haicun Zhang, Yanbo Lin, Canglu Wu, Fangling Cheng, Danqing Bao, Yuyan Chen

“…Following operation, there were significant differences between the 2 groups with respect to RIS at 1 week and 6 months postsurgery and hemoglobin levels on postoperative day 2. …”
Get full text

Changes in Corneal Volume at Different Areas and Its Correlation with Corneal Biomechanics after SMILE and FS-LASIK Surgery by Pinghui Wei, George PM Cheng, Jiamei Zhang, Alex LK Ng, Tommy CY Chan, Vishal Jhanji, Yan Wang

“…CV was measured with Scheimpflug-based corneal topography at preoperatively and at day 1, week 1, and months 1 and 3 postoperatively. CV measured within 5 mm diameter was defined as central region volume (CV5) and between 5 mm and 10 mm diameter was defined as peripheral region volume (CV5-10). …”
Get full text