Chemotherapy plus therapeutic plasmapheresis with 4% human albumin solution in multiple myeloma patients with acute kidney injury: a prospective, open-label, proof-of-concept study by Tianzhi Wu, Dandan Liu, Shangqin Liu, Hui Xiao, Bei Xiong, Yi Zhou, Yafen Xiong, Qin Cui, Jiang Wu, Minghui Liu, Hongli Liu, Yiming Li, Meixin Wang, Xueqin Bao, Ye Li, Fuling Zhou

“…The primary endpoints were changes in renal function over 18 weeks and survival outcomes at 36 months. The secondary endpoints were the incidence of adverse reactions and symptom improvement. …”
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Your period and your pregnancy, a cohort study of pregnant patients investigating the associations between menstruation and birth outcomes in Australia: study protocol by Miranda Davies-Tuck, Billie Bradford, Adrienne Gordon, Beverley Vollenhoven, Kirsten Rebecca Palmer, Kirstin Tindal, Caroline E Gargett, Fiona Cousins, Stacey Ellery

“…Participants will also be invited to complete an optional fetal movements survey at 28–32 and 36+ weeks’ gestation, and consent for placental collection at the time of birth will be sought.Ethics and dissemination Ethics approval was obtained from Monash Health Human Research Ethics Committee (83559) on 24 April 2024. …”
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Aloe Emodin Reduces Cardiac Inflammation Induced by a High-Fat Diet through the TLR4 Signaling Pathway by Yingfu Chen, Burong Feng, Ye Yuan, Juan Hu, Wei Zhao, Huiwei Jiang, Wen Li, Ziyi Fan, Zhimin Du

“…We used a mouse model of hyperlipidemia caused by a high-fat diet (HFD) for 10 weeks and cell culture experimental models of inflammation in the heart stimulated by PA for 14 h. …”
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Enhancing elemental release and antibacterial properties of resin-based dental sealants with calcium phosphate, bioactive glass, and polylysine by Phatpicha Lertwisitphon, Yotsavee Worapasphaiboon, Nichapa Champakanan, Arnit Toneluck, Parichart Naruphontjirakul, Anne M. Young, Rattapha Chinli, Phoom Chairatana, Supanan Sucharit, Piyaphong Panpisut

“…The element release over 4 weeks was measured using inductively coupled plasma-optical emission spectrometry (ICP-OES) (n = 3). …”
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Fermented sugarcane juice-derived probiotic Levilactobacillus brevis RAMULAB54 enhances lipid metabolism and glucose homeostasis through PPAR-γ activation by V. B. Chandana Kumari, Ramith Ramu, Sujay S. Huligere, Shashank M. Patil, Shivasharanappa Nayakvadi, Sharath Bijoor, Uma Venkateswaran Manjappara, Mohammad Z. Ahmed, Ling Shing Wong

“…In vivo, male Wistar rats in hyperlipidemic and streptozotocin-induced hyperglycemic models were treated with LB13243 for 4 weeks, followed by analysis of food intake, body weight, serum glucose, lipids, and histopathology. …”
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Real-World Efficacy and Safety of Avelumab Plus Axitinib in Metastatic Renal Cell Carcinoma: Results from the Ambispective RAVE-Renal Study by Ilya Tsimafeyeu, Vyacheslav Chubenko, Olga Baklanova, Alexey Kalpinskiy, Sufia Safina, Andrei Lebedinets, Vladislav Petkau, Elvira Parsadanova, Maria Turganova, Aleksei Shkurat, Natalia Tovbik, Elena Tkacheva, Yulia Anzhiganova, Olga Novikova, Varvara Bragina, Ruslan Zukov, Rashida Orlova

“…Patients received avelumab (800 mg intravenously every 2 weeks) plus axitinib (5 mg orally twice daily). The primary endpoints were median progression-free survival (PFS) and objective response rate (ORR). …”
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The Long-Term Immunity of a Microneedle Array Patch of a SARS-CoV-2 S1 Protein Subunit Vaccine Irradiated by Gamma Rays in Mice by Eun Kim, Muhammad S. Khan, Juyeop Shin, Shaohua Huang, Alessandro Ferrari, Donghoon Han, Eunjin An, Thomas W. Kenniston, Irene Cassaniti, Fausto Baldanti, Dohyeon Jeong, Andrea Gambotto

“…The MAP delivery induced sgnificantly higher and longer-lasting S1-specific IgG responses for up to 70 weeks compared to intramuscular injections. Robust Th2-prevalent immune responses were generated in all the groups vaccinated via the MAP and significant neutralizing antibodies were elicited at 15 and 45 µg, showing dose-sparing potential. …”
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Osilodrostat treatment in patients with Cushing’s disease of Asian or non-Asian origin: a pooled analysis of two Phase III randomized trials (LINC 3 and LINC 4) by Akira Shimatsu, Beverly MK Biller, Maria Fleseriu, Rosario Pivonello, Eun Jig Lee, Rattana Leelawattana, Jung Hee Kim, Rama Walia, Yerong Yu, Zhihong Liao, Andrea Piacentini, Alberto M Pedroncelli, Peter J Snyder

“…Median (minimum–maximum) osilodrostat dose was 3.8 (1–25) and 7.3 (1–47) mg/day in Asian and non-Asian patients, respectively. mUFC control was achieved at weeks 48 and 72 in 64.3% and 68.1% of Asian and 68.2% and 75.8% of non-Asian patients. …”
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Impact of school salad bars on fruit and vegetable selection, intake, and waste in Mid-Atlantic elementary schools by Melanie K. Bean, Suzanne E. Mazzeo, Lilian de Jonge, Laura Thornton, Hollie Raynor, Ashley Mendoza, Sarah Farthing, Bonnie Moore

“…Digital imagery plate waste methods were applied at baseline and 4–6 weeks after schools installed salad bars (post). …”
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Balance and Gait Improvements of Postoperative Rehabilitation in Patients with Parkinson’s Disease Treated with Subthalamic Nucleus Deep Brain Stimulation (STN-DBS) by Kazunori Sato, Noriaki Aita, Yoshihide Hokari, Eriko Kitahara, Mami Tani, Nana Izawa, Kozo Hatori, Ryota Nakamura, Fuyuko Sasaki, Satoko Sekimoto, Takayuki Jo, Genko Oyama, Taku Hatano, Yasushi Shimo, Hirokazu Iwamuro, Atsushi Umemura, Nobutaka Hattori, Toshiyuki Fujiwara

“…The purpose of this study was to examine changes in balance ability, gait function, motor performance, and ADLs following 2 weeks of postoperative rehabilitation in PD patients treated with STN-DBS. …”
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Pomegranate peel powder and extract improved weight control, lipid metabolism and gut microbiota in hamsters fed with standard american diets by Xingzhu Wu, Wallace Yokoyama, Yuqing Tan, Glenn Bartley, Ling Chen, James Pan, Priscila Alves Buongiorno, Jose Berrios, Tara McHugh, Zhongli Pan

“…Hamsters were fed either the HF, or the HF diet supplemented with 2.5 % or 5 % PPE (LE and HE, respectively), or 5 % or 10 % PPP (low-peel (LP) and high-peel (HP), respectively. After 4 weeks of feeding, hamsters gained 16.10- 33.82 g of weight and the feeding efficacy ranged from 0.10 to 0.18. …”
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Protein Level and Infantile Diarrhea in a Postweaning Piglet Model by Jing Gao, Jie Yin, Kang Xu, Hui Han, ZeMin Liu, ChenYu Wang, TieJun Li, YuLong Yin

“…The experiment lasted for two weeks and all animals were free to eat and drink water ad libitum. …”
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Peer-assisted telemedicine hepatitis-C treatment for people who use drugs in rural communities: a mixed methods study by Kim Hoffman, Gillian Leichtling, Sarah Shin, Andrew Seaman, Tonhi Gailey, Hunter C. Spencer, P. Todd Korthuis

“…The Oregon HOPE TeleHCV study randomized PWUD living with HCV in rural Oregon to peer-facilitated and streamlined telemedicine HCV treatment (Peer TeleHCV) versus enhanced usual care (EUC) and assessed sustained virologic response at 12 weeks post treatment (SVR12). Peer Support Specialists (peers) conducted HCV screening in the community, facilitated pretreatment evaluation and linkage to telemedicine HCV treatment clinicians, and supported Peer TeleHCV study participants in HCV medication adherence. …”
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Combination of mentor-based and resident-based learning may benefit to improving the ability of clinical practice in resident training by Min Li, Tao Liu, Yiqiong Wen, Min Zhang, Wenye Zhu, Xuming Wang, Yunjiao Hou, Lin Li, Anju Zu, Shibo Sun

“…The CMRL group adopted CMRL and MBL group adopted MBL for daily medical teaching for four weeks. The primary outcome measure was the difference in trainee's scores of comprehensive analysis ability between CMRL group and MBL group after teaching. …”
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Biotechnological Phytocomplex of <i>Zanthoxylum piperitum</i> (L.) DC. Enhances Collagen Biosynthesis In Vitro and Improves Skin Elasticity In Vivo by Giovanna Rigillo, Giovanna Pressi, Oriana Bertaiola, Chiara Guarnerio, Matilde Merlin, Roberto Zambonin, Stefano Pandolfo, Angela Golosio, Francesca Masin, Fabio Tascedda, Marco Biagi, Giulia Baini

“…The in vivo assessment was performed by measuring biophysical skin parameters such as hydration, elasticity, and roughness in female volunteers for a period of six weeks. <b>Results:</b> In vitro, ZPP exhibited non-cytotoxicity at all concentrations tested. …”
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The effect of prone positioning on maternal haemodynamics and fetal wellbeing in the third trimester-A primary cohort study with a scoping review. by Laura Ormesher, Jessica Catchpole, Linda Peacock, Heather Pitt, Anastasia Fabian-Hunt, Dexter Hayes, Claudia Popp, Jason M Carson, Raoul van Loon, Lynne Warrander, Karli Büchling, Alexander E P Heazell

“…<h4>Methods</h4>Twenty-one women >28 weeks' gestation underwent non-invasive CO monitoring (Cheetah) every 5 minutes and continuous fetal heart rate monitoring (MONICA) in left lateral (20 minutes), prone (30 minutes), followed by left lateral (20 minutes). …”
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Early COVID-19 and protection from Omicron in a highly vaccinated population in Ontario, Canada: a matched prospective cohort study by Altynay Shigayeva, Christopher Kandel, Lubna Farooqi, Zoe Zhong, Anne-Claude Gingras, Brenda L. Coleman, Lois Gilbert, Wayne L. Gold, Maria Major, Tony Mazzulli, Samira Mubareka, Jelena Vojicic, Jingyan Yang, Pingping Zhang, Catherine Martin, Moe H. Kyaw, John M. McLaughlin, Allison McGeer

“…Participants completed baseline surveys then surveys every two weeks until January 2023. Multivariable Cox regression was used to assess factors associated with COVID-19 infection during the first 14 months of Omicron. …”
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Effects of Glucagon-Like Peptide-1 Receptor Agonists on Weight Loss in Patients with Type 2 Diabetes: A Systematic Review and Network Meta-Analysis by Feng Sun, Sanbao Chai, Lishi Li, Kai Yu, Zhirong Yang, Shanshan Wu, Yuan Zhang, Linong Ji, Siyan Zhan

“…The mean duration of 51 RCTs was 31 weeks. Exenatide 10 μg twice daily (EX10BID) reduced weight compared with exenatide 5 μg twice daily (EX5BID), liraglutide 0.6 mg once daily (LIR0.6QD), liraglutide—1.2 mg once daily (LIR1.2QD), and placebo treatment, with mean differences of −1.07 kg (95% CI: −2.41, −0.02), −2.38 kg (95% CI: −3.71, −1.06), −1.62 kg (95% CI: −2.79, −0.43), and −1.92 kg (95% CI: −2.61, −1.24), respectively. …”
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Maternal neonicotinoid pesticide exposure impairs glucose metabolism by deteriorating brown fat thermogenesis by Wenwen Zhu, Jiali Fang, Chenbo Ji, Hong Zhong, Tianying Zhong, Xianwei Cui

“…Methods: 100 pregnant women who completed a 75 g oral glucose tolerance test (OGTT) at 24–28 weeks of gestation were enrolled. Urinary concentrations of seven widely used NEOs were quantified using ultra-high performance liquid chromatography multiple reaction monitoring mass spectrometry (UHPLC-MRM-MS/MS). …”
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Sorafenib Prevents Escape from Host Immunity in Liver Cirrhosis Patients with Advanced Hepatocellular Carcinoma by Hidenari Nagai, Takanori Mukozu, Daigo Matsui, Takenori Kanekawa, Masahiro Kanayama, Noritaka Wakui, Kouichi Momiyama, Mie Shinohara, Kazunari Iida, Koji Ishii, Yoshinori Igarashi, Yasukiyo Sumino

“…Sorafenib was administered at a dose of 200–800 mg/day for 4 weeks. Blood samples were collected before and after treatment. …”
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