Neuroprotective effects of curculigoside against Alzheimer’s disease via regulation oxidative stress mediated mitochondrial dysfunction in L-Glu-exposed HT22 cells and APP/PS1 mice... by Wenqi Wang, Yidi Qu, Siyu Li, Jinyu Chu, Hongxin Yang, Lirong Teng, Di Wang

“…Observably, CCG in L-Glu-damaged HT22 cells suppressed apoptosis, reduced the accumulation of reactive oxygen species, balanced the mitochondrial membrane potential and prevented the over-influx of calcium. In APP/PS1 mice, 4-week CCG administration significantly improved their memory and behavioral impairments, enhanced the function of cholinergic system, reduced the deposition of Aβ and neurofibrillary fiber tangles caused by tau phosphorylation, and suppressed the development and progression of oxidative stress in brains of APP/PS1 mice. …”
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Evaluation of Three Adolescent Sexual Health Programs in Ha Noi and Khanh Hoa Province, Vietnam by Van Pham, Hoang Nguyen, Le Huu Tho, Truong Tan Minh, Porntip Lerdboon, Rosemary Riel, Mackenzie S. Green, Linda M. Kaljee

“…Programs were delivered over a ten-week period in the communities by locally trained facilitators. …”
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Impact of the COVID-19 lockdown in the United Kingdom on adolescent's time use (CONTRAST study). by Irina Pokhilenko, Emma Frew, Marie Murphy, Miranda Pallan

“…There was an overall decrease in the amount of time spent on school work, an increase in screen time, and an increase in sleep duration during the week. Descriptive analysis showed evidence of inequalities with changes in time use. …”
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Two Imported Malaria Cases with Delayed Response to Treatment in Hatay by Tuğba Kaya, Mehmet Çabalak, Gülnaz Çulha, Ceren Ünal

“…The patient was discharged after a 3-week follow-up. The study is presented to draw attention to the increasing cases of imported malaria in Hatay and the increase of malaria cases that respond late to treatment in recent years.…”
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Gene Expression Profiling of the Sciatic Nerve in Streptozotocin-Induced Diabetic Rats with Peripheral Neuropathy by Yiji Tu, Zenggan Chen, Feng Zhang, Zhenglin Di, Junhui Zhang, Li Cai

“…Microarray was performed on the sciatic nerve tissues from control rats and DPN rats at then6th week after diabetes induction, and differentially expressed genes (DEGs) between them were identified and applied for further bioinformatic analyses. …”
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Maternal Serum Uric Acid as an Index of Perinatal Outcomes in Severe Preeclampsia by Rozhan Yassin Khalil, Awat Saber Muhammed

“…Preeclampsia is a multisystem disorder characterized by gestational hypertension after the 20th week of gestation with proteinuria, is common and dangerous adverse event of pregnancy. …”
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Effect of a Selective Progesterone Receptor Modulator on Induction of Apoptosis in Uterine Fibroids In Vivo by Petr Horak, Michal Mara, Pavel Dundr, Kristyna Kubinova, David Kuzel, Robert Hudecek, Roman Chmel

“…Immunohistochemical examination of fibroid tissue, using avidin-biotin complex and cleaved caspase-3 antibody for detecting apoptosis, was performed in premenopausal women who underwent 12-week treatment with oral SPRM (6 patients with 5 mg and 5 patients with 10 mg of ulipristal acetate per day) or gonadoliberin agonist (GnRHa, 17 patients) and subsequent myomectomy or hysterectomy for symptomatic uterine fibroids. …”
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Investigation of the Protective Effect of Probiotic Lactobacillus plantarum Ep-M17 on the Hepatopancreas of Penaeus vannamei by Xiaoman Hu, Wenlong Xu, Hao Li, Bowen Lu, Yang Du, Jiong Chen

“…To address this knowledge gap, our present study investigated the histological changes, enzyme activity, gene transcription, and metabolite levels in the hepatopancreas of shrimp after a 4-week diet supplemented with Ep-M17. The results revealed that incorporating Ep-M17 into the shrimp’s diet alleviated the damage by V. parahaemolyticus E1 infection in hepatopancreatic cells. …”
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Efficacy and Safety of Immunotherapy with Interferon-Gamma in the Management of Chronic Sulfur Mustard-Induced Cutaneous Complications: Comparison with Topical Betamethasone 1% by Yunes Panahi, Amirhossein Sahebkar, Seyyed Masoud Davoudi, Mojtaba Amiri, Fatemeh Beiraghdar

“…Forty subjects who were suffering from chronic skin complications of SM and were diagnosed to have severe atopic dermatitis, were assigned to IFN-γ (50 μg/m2) subcutaneously three times per week (n=20) or betamethasone valerate topical cream 0.1% (n=20) every night for 30 days. …”
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Lower serum magnesium level is an important risk factor for erythropoiesis-stimulating agents hypo-responsiveness in hemodialysis patients by Hayam Hebah, Shaimaa Abdelmegied, Dina Osman, Lina Khedr

“…ERI mean values were (13.63 ± 3.17 Vs 10.52 ± 2.74 IU/week/kg) which was also found to be a significant p-value < 0.001. …”
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Negative Influence of a Long-Term High-Fat Diet on Murine Bone Architecture by Hinrich Fehrendt, Thomas Linn, Sonja Hartmann, Gabor Szalay, Christian Heiss, Reinhard Schnettler, Katrin Susanne Lips

“…Thus, the aim of the present study was to investigate the influence of diet-induced mild obesity (11% increased body weight compared to control) on bone microstructure in mice. Four-week-old male C57BL/6J mice received a high-fat diet (HFD, 60% kcal from fat) and were analyzed by means of dual X-ray absorptiometry, histological methods, real-time RT-PCR, and transmission electron microscopy in comparison to control animals (10% kcal from fat). …”
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Wharton’s Jelly Mesenchymal Stem Cell Conditioned Medium Ameliorates Diabetes-Induced Testicular Damage and Sperm Abnormalities by Mitigating Oxidative Stress, Apoptosis, and Infla... by Mojtaba Sargazi, Narges Karbalaei, Saied Karbalay-Doust, Sara Keshtgar, Zohre Aghaei

“…In the early treatment groups, insulin (3 U/day, subcutaneously) and WJMSCs-CM (10 mg/week, intraperitoneally) were administered immediately after diabetes induction; in the late treatment groups, these interventions began 30 days postinduction. …”
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The Diagnostic Values of Ischemia-Modified Albumin in Patients with Acute Abdominal Pain and Its Role in Differentiating Acute Abdomen by Selman Yeniocak, Fatma Saraç, Mustafa Yazıcıoğlu, Nadiye Karabulut, Akın Ünal, Esma Yücetaş, Macit Koldaş, İbrahim Akkoç, Mustafa Ekici, Togay Evrin

“…These consisted of 194 patients (Group 1) with nontraumatic abdominal pain commencing in the preceding week, who were definitely diagnosed and either hospitalized in a specific department or planned for discharge, and a control group of 140 patients (Group 2). …”
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Differential Effects of Chronic Pulsatile versus Chronic Constant Maternal Hyperglycemia on Fetal Pancreatic β-Cells by Mackenzie S. Frost, Aqib H. Zehri, Sean W. Limesand, William W. Hay, Paul J. Rozance

“…We measured the impact of one week of chronic constant hyperglycemia (CHG, n=6) versus pulsatile hyperglycemia (PHG, n=5) versus controls (n=7) on the percentage of the fetal pancreas staining for insulin (β-cell area), mitotic and apoptotic indices and size of fetal β-cells, and fetal insulin secretion in sheep. …”
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Digital measurement of ocular microtremor in Parkinson's disease: Protocol for a pilot study to assess reliability and clinical validation. by Lisa Graham, Rodrigo Vitorio, Richard Walker, Alan Godfrey, Rosie Morris, Samuel Stuart

“…We will recruit 30 People with PD, 30 people with suspected PD and 30 age-matched healthy control participants for assessment of OMT. 20 People with PD will complete a test-retest reliability assessment at the same approximate time, exactly one week after their initial visit under the same conditions to explore consistency. …”
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Safety and immunogenicity in humans of enterotoxigenic Escherichia coli double mutant heat-labile toxin administered intradermally by Marcela F. Pasetti, Patricia L. Milletich, Jessica A. White, Jessica Butts, Rebecca C. Brady, Michelle D. Dickey, Cassandra Ballou, Nicole Maier, Marcelo B. Sztein, Shahida Baqar, A. Louis Bourgeois, David I. Bernstein

“…Subjects received up to three immunizations at three-week intervals. The vaccine was safe, although it induced mild local and some gastrointestinal adverse events, as well as frequent hyperpigmentation at the injection site. …”
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Facial Mobility after Maxilla-Mandibular Advancement in Patients with Severe Obstructive Sleep Apnea Syndrome: A Three-Dimensional Study by Laura Verzé, Francesca Antonella Bianchi, Niccolò Barla, Serena Maria Curti, Giovanni Gerbino, Guglielmo Amedeo Ramieri

“…Their facial surface data was acquired using a 3D laser scanner one week before (T1) and 12 months after (T2) orthognathic surgery. …”
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Balancing physical development and health in adolescents through controlled High-Intensity Training by Stanislav Lazarev, Iryna Kryventsova, Vasyl Lutskyi

“…The EG participated in high-intensity training sessions twice a week, with each session lasting 20 minutes. The program's effectiveness was evaluated using a series of physical ability tests. …”
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Huerto urbano Adelfas (Madrid, 24 de enero de 2021) by Claudia Antón Biezma

“…It is a big space, it gets sun light, neighbours water it twice per week and it is open to everyone. The main advantage of this type of garden is for city kids to be able to be in contact with something rural, where they can plant and grow vegetables. …”
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Herbal Mouthwash Containing Extracts of Baccharis dracunculifolia as Agent for the Control of Biofilm: Clinical Evaluation in Humans by Vinícius Pedrazzi, Mateus Freire Leite, Reisla Cristina Tavares, Sandra Sato, Glauce Crivelaro do Nascimento, João Paulo Mardegan Issa

“…In measuring the time after use of mouthwash (t=1), there was no difference between products (P=0.602); that is, subjects in the study had a similar PI after the first use. After one week (t=2), there was no difference between the four products evaluated (P=0.674), so, all research individuals completed the study with a similar reduction in dental biofilm between themselves but it was different from initial state (Friedman test). …”
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