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7641
Wenxin Granules Influence the TGFβ-P38/JNK MAPK Signaling Pathway and Attenuate the Collagen Deposition in the Left Ventricle of Myocardial Infarction Rats
Published 2019-01-01“…Gavage was given once a day for 4 weeks. The changes of cardiac hemodynamics were detected by the catheter method, morphological changes were observed by HE staining, and myocardial tissue collagen volume was counted by Immunohistochemistry combined with Masson staining, and the expression of inflammatory TGFβ-p38/JNK MAPK signal pathway markers was detected by Western blot. …”
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7642
Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s...
Published 2025-02-01“…It delivers a structured sequence of 103 messages over 14 weeks to support the uptake and maintenance of physical activities following stroke rehabilitation.Outcomes Data on recruitment, retention and satisfaction were collected. …”
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7643
Longitudinal DNA methylation profiles in saliva of offspring from mothers with gestational diabetes: associations with early childhood growth patterns
Published 2025-01-01“…Samples were collected at two time points: 8–10 weeks postpartum and at one year of age. Epigenome-wide analysis of over 850,000 CpG sites was conducted using the Illumina Methylation EPIC Bead Chip. …”
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7644
Vision Improvement after Osimertinib Treatment in Paraneoplastic Optic Neuropathy Associated with Lung Adenocarcinoma
Published 2021-01-01“…Slit-lamp examination and funduscopy showed no abnormal findings. Two weeks later, her BCVA decreased to 0.2 in the RE and 0.01 in the LE. …”
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7645
Evaluation of Biologics ACE2/Ang(1–7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies
Published 2024-12-01“…<b>Results:</b> The ACE2 protein was stable in the gum for at least up to 78 weeks. The toxicology study revealed the dose-related drug delivery to the plasma and increases in the AUC (56.6%) and Cmax (52.9%) after 28 high-dose gavages (95% C.I.), although this quantitation excludes exogenously delivered membrane-associated ACE2/Ang(1–7). …”
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7646
Testicular Nitric Oxide and Thiobarbituric Acid Reactive Substances Levels in Obstructive Azoospermia: A Possible Role in Pathophysiology of Infertility
Published 2006-01-01“…Animals were sacrificed 8 weeks after surgery. Testes were removed and used for the evaluation of nitrate/nitrite and TBARS levels and for histology. …”
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7647
Effects of hydrolyzed collagen supplementation for Skin Anti-Aging
Published 2025-01-01“…Overall, it can be concluded that as little as 12 weeks of hydrolyzed fish collagen supplementation improves the quality and appearance of skin in the aging population.Importantly, HC-containing formulations were found to be safe and well-tolerated. …”
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7648
Acute effect of endurance exercise on human milk insulin concentrations: a randomised cross-over study
Published 2025-01-01“…Our aim was to determine the acute effects of two endurance exercise protocols on human milk insulin concentration in exclusively breastfeeding individuals.MethodsIn a randomised cross-over trial, 20 exclusively breastfeeding participants who were 6–12 weeks postpartum completed three conditions on separate days: (1) moderate-intensity continuous training (MICT), (2) high-intensity interval training (HIIT), and (3) no activity (REST). …”
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7649
Transconjunctival correction of involutional entropion: A video demonstration
Published 2025-02-01“…The suture removal especially at the eyelid margin should be removed at 2–3 weeks to provide a strong attachment of inferior retractors with the tarsal surface. …”
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7650
A Study of Combined Onabotulinumtoxin A and Hyaluronic Acid Filler for the Treatment of Enlarged Facial Pores
Published 2025-01-01“…The outcomes were measured by pore volume, visual assessment, pain score, improvement score, and side effects at various time intervals up to 24 weeks. Results: This study investigated the effects of onaBoNT-A monotherapy or in combination with HA filler on facial pore size and skin roughness. …”
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7651
Jiawei Suanzaoren decoction for the treatment of perimenopausal insomnia: clinical observation and experimental study
Published 2025-01-01“…The treatment group was treated with Jiawei Suanzaoren decoction, while the control group was treated with lorazepam for 4 weeks. The study observed and compared the Pittsburgh Sleep Quality Index (PSQI), Kupperman score, Polysomnography (PSG) and sex hormone levels of two groups before and after treatment. …”
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7652
The association between serum ferritin levels and the risk of gestational diabetes mellitus: a prospective cohort study
Published 2025-01-01“…GDM was determined by a 75 g oral glucose tolerance test at 24–28 weeks of gestation. Multivariate modified Poisson regression was performed to estimate the independent relationship between serum ferritin levels and the incident GDM. …”
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7653
Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma
Published 2018-01-01“…Consistently, use of hPGC-1α_hMPCs produced significantly increased contractile force one to three weeks postinjury. PET imaging showed distinct differences in radiotracer signals ([18F]Fallypride and [11C]Raclopride (both targeting dopamine 2 receptors (D2R)) and [64Cu]NODAGA-RGD (targeting neovascularization)) between GFP_hMPCs and hD2R_hPGC-1α_hMPCs. …”
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7654
Electroporation assisted delivery of Roussin salt porphyrin-based conjugated carbon nanoparticles for sono–X-ray–photodynamic prostate cancer in vitro and in vivo treatment
Published 2025-01-01“…The study treatment protocol started only after PCa induction, and involved daily administration of EP@RRBP-CNP as SXPDT sensitizer whether or not to be exposed to photo–(X-ray) or sono–(US) or a combination of them for 3 min for a period of 2 weeks. Results Indicated that CNP is a useful RRBP delivery mechanism that targets PCa cells directly. …”
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Time without PSA recurrence after radical prostatectomy as a predictor of future biochemical recurrence, metastatic disease and prostate cancer death: a prospective Scandinavian co...
Published 2022-12-01“…Four patients were excluded due to surgery-related death (n=1) or salvage radiotherapy or hormonal treatment within 6 weeks from surgery (n=3).Primary outcome measures Cumulative incidences and absolute differences in metastatic disease and prostate cancer death.Results We analysed 302 patients with complete follow-up during a median of 24 years. …”
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7656
Characterization of jamun (Syzygium cumini) juice fortified with nanoemulsified vitamin D3: In vitro and in vivo assessment of its nutraceutical value and anti-diabetic potential
Published 2025-01-01“…Vitamin D3 showed 82 % release profile in simulated gastrointestinal fluids. After 4 weeks of VDFJJ intervention in vitamin D-deficient animal models, serum levels of 25-OHD, PTH, calcium, phosphorus, and ALP were significantly improved. …”
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Effect of Dietary Supplementation of <i>Durvillaea Antarctica</i> Meal on Production and Meat Quality Traits of Lambs
Published 2025-01-01“…One pen served as a control, while the remaining two were supplemented with diets containing 5% and 10% <i>Durvillaea antarctica</i> meal. After 9 weeks, the animals were slaughtered. The dietary treatments did not significantly affect body weight and blood biochemical parameters. …”
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7658
Maternal and Perinatal Outcome in Women with Systemic Lupus Erythematosus: A Retrospective Bicenter Cohort Study
Published 2017-01-01“…Methods. Pregnancies > 16 weeks gestation of SLE patients receiving joint care from rheumatologists and gynecologists in two tertiary centers in the Netherlands between 2000 and 2015 were included. …”
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The Effect of Exosomes Derived from Human Umbilical Cord Mesenchymal Stromal/Stem Cells on the Regeneration of Human Pulpectomized Tooth: A Case Report
Published 2025-01-01“…Clinical evaluations, including visual inspection, palpation, pulp vitality tests, radiography, and cone beam computed tomography (CBCT) imaging, were conducted over 24 weeks post-treatment. The SEM and TEM images confirmed the effective isolation and characterization of exosomes. …”
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7660
Efficacy and Safety of Transcranial Magnetic Stimulation for Attention‐Deficit Hyperactivity Disorder: A Systematic Review and Meta‐Analysis
Published 2025-01-01“…According to the core symptoms, TMS significantly improved inattention (SMD = −0.94, 95% CI = −1.33 to −0.56, p < 0.001) and hyperactivity/impulsivity (SMD = −0.98, 95% CI = −1.27 to −0.69, p < 0.001) compared to non‐TMS interventions after 3–6 weeks of intervention. During the 1‐month follow‐up, the TMS group still demonstrated a significant improvement in inattention symptoms compared to the non‐TMS group (SMD = −0.67, 95% CI = −1.06 to 0.28, p < 0.001). …”
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