Development of a Recombinant Omicron BA.1 Subunit Vaccine Candidate in Pichia pastoris by Sibel Kalyoncu, Dogu Sayili, Ayca Zeybek Kuyucu, Hakan Soyturk, Seyda Gullu, Busra Ersayan, Ibrahim Oguzhan Tarman, Mehmet Ender Avci, Olcay Mert, Umut Haskok, Ege Tekin, Huseyin Akinturk, Ridvan Orkut, Aysegul Demirtas, Idil Tilmensagir, Ceren Ulker, Bilgi Gungor, Mehmet Inan

“…The long‐term immunological response in mice was measured by analyzing serum antibody titers and T‐cell response of splenocytes after 60 weeks. Interestingly, IgG titers and Th1 response were significantly high even after a year. …”
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Differences in Characteristics of Peripartum Patients Who Did and Did Not Require an Upgrade to the Intensive Care Unit: A Propensity Score Matching Study by Jennifer A. Walker, Jerry M. Yang, Saad Pirzada, Manahel Zahid, Samantha Asuncion, Amanda Tuchler, Gillian Cooper, Allison Lankford, Emad Elsamadicy, Quincy K. Tran

“…Mean maternal age (±Standard Deviation) and gestational age for the group was 29.5 (±5.8) years and 31.5 (±7.5) weeks, respectively. The Median Sequential Organ Failure Assessment Score [Interquartile] at ward admission for the controls was 0 [0–1] versus 2 [0–3.3, <i>p</i> = 0.001] for upgrade patients. …”
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Clarification of factors associated with post-artesunate delayed hemolysis (PADH): Analysis of 327 patients with severe imported Plasmodium falciparum malaria in France by Pierre-Louis Conan, Marc Thellier, Eric Kendjo, Sandrine Houzé, Rémonie Seng, Stéphane Jauréguiberry

“…Background: Post-Artesunate delayed hemolysis (PADH) occurs in approximately 15 % of treated patients 2–3 weeks after artesunate administration. Identifying risk markers for PADH would help predict which patients are at higher risk. …”
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In vivo and in silico study of europinidin against streptozotocin-isoproterenol-induced myocardial damage via alteration of hs-CRP/CPK-MB/Caspase-3/Bcl-2 pathways by Khalid Saad Alharbi, Muhammad Afzal, Fahad A. Al-Abbasi, Ehssan Moglad, Salwa D. Al-Qahtani, Naif A. R. Almalki, Faisal Imam, Nadeem Sayyed, Imran Kazmi

“…Europinidin 10 and 20 mg/day was administered orally for 4 weeks after validation of diabetes (glucose > 250 mg/dl) on the 7th day. …”
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Design, Content and Ecological Validity and Reliability of the Physical Activity and Sport Habits Questionnaire for Children Aged 8–12 Years in the Province of Gipuzkoa (Spain) by Aduna Badiola-Lekue, Irantzu Ibañez, Maite Fuentes, Javier Yanci, Oidui Usabiaga, Aitor Iturricastillo

“…For reliability testing, 276 schoolchildren aged 8 to 12 completed the questionnaire twice, with a time interval of two weeks to two months. Statistical analyses included the Wilcoxon test to compare expert ratings, effect size and percentage change calculations for magnitude assessment, and McNemar, McN-Bowker or Wilcoxon tests to compare differences between initial and repeat responses. …”
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Efficacy of the Foodbot Factory digital curriculum-based nutrition education intervention in improving children’s nutrition knowledge, attitudes and behaviours in elementary school... by Wendy Lou, Michael Farkouh, JoAnne Arcand, Jacqueline Marie Brown, Saman Tahir, Beatriz Franco-Arellano, Ann LeSage, Janette Hughes, Bill Kapralos, Ellen Vogel, Claire Tugault-Lafleur

“…Outcomes will be assessed at baseline, immediately postintervention, and 4 weeks and 3 months postintervention using the Nutrition Attitudes and Knowledge questionnaire, the Block Kids Food Screener, a modified Family Nutrition and Physical Activity screener and an acceptability questionnaire. …”
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Evaluation of a transdiagnostic mental health intervention in German primary care: study protocol for a parallel-group, two-arm, cluster randomised controlled pilot study by Christopher Ebert, Marie Vogel, Jochen Gensichen, Hanna Reif, Lena Grögor, Lukas Junker, Thomas Ehring, Alkomiet Hasan, Stefan Leucht, Kirsten Lochbühler, for the POKAL-Group

“…In both study groups, treatment will be carried out in four 20-min sessions over 12-weeks. Self-report questionnaires will be completed before treatment initiation (only patients) and after treatment completion (patients and general practitioners) to assess feasibility and acceptability (i.e., treatment recruitment, delivery, response, effectiveness, unintended consequences and maintenance) as well as potential effectiveness (i.e., change in transdiagnostic factors). …”
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The Role of β-Catenin in Th1 Immune Response against Tuberculosis and Profiles of Expression in Patients with Pulmonary Tuberculosis by Kunlong Xiong, Jinxia Niu, Ruijuan Zheng, Zhonghua Liu, Yanzheng Song, Lin Wang, Changtai Zhu, Lin Fan

“…In this study, CD4+ T cell-specific β-catenin conditional knockout mice (β-CAT-cKO mice) were aerosol infected with Mycobacteria tuberculosis (Mtb) H37RV with wild-type mice as controls. Four weeks after infection, the mRNA expression of IFN-γ, TNF-α, and TCF-7 in the lungs of mice was measured. …”
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Hyperspectral imaging in living and deceased donor kidney transplantation by Rasmus Wrigge, Robert Sucher, Fabian Haak, Hans-Jonas Meyer, Julia Unruh, Hans-Michael Hau, Matthias Mehdorn, Hans-Michael Tautenhahn, Daniel Seehofer, Uwe Scheuermann

“…Kidney grafts with low StO2 values (cut-off point 0.6) showed reduced renal function with a low glomerular filtration rate and elevated urea levels in the first two weeks after KT. Three years after KT, graft survival was also inferior in the group with initially low StO2 values. …”
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Social Media Use and Oral Health–Related Misconceptions in Saudi Arabia: Cross-Sectional Study by Rahaf Hamdan BinHamdan, Salwa Abdulrahman Alsadhan, Arwa Zohair Gazzaz, AlBandary Hassan AlJameel

“…MethodsA cross-sectional survey was conducted over 10 weeks, targeting adults aged 15 years and older in Saudi Arabia. …”
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Cardiovascular Protection of Nephropathic Male Patients by Oral Food Supplements by Annalisa Noce, Giulia Marrone, Manuela Di Lauro, Silvia Urciuoli, Anna Pietroboni Zaitseva, Georgia Wilson Jones, Nicola Di Daniele, Annalisa Romani

“…In this study, 23 male nephropathic patients and 10 age and body composition parameter matched healthy males (control group) were enrolled and took 3 cps/day of OFS for 5 weeks. At the end of the study, the nephropathic patient group showed a statistically significant reduction in the following laboratory parameters: total cholesterol (TC) (p=0.044), atherogenic index TC/high-density lipoprotein cholesterol (p=0.010), inflammatory parameters (C-reactive protein, p=0.048, and erythrocyte sedimentation rate, p=0.019), systolic (p=0.044), and diastolic arterial blood pressure (p=0.003). …”
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Reactive arthritis incidence in a community cohort following a large waterborne campylobacteriosis outbreak in Havelock North, New Zealand by Nicholas Jones, Rebecca Grainger, Michael G Baker, Tim Wood, Tiffany A Walker, Terence Quirke, Rebekah Roos, Jill Sherwood, Graham Mackereth, Tomasz Kiedrzynski, Rachel Eyre, Shevaun Paine, Anita Jagroop

“…Probable ReA was defined as spontaneous onset of pain suggestive of inflammatory arthritis in ≥1 previously asymptomatic joint for ≥3 days occurring ≤12 weeks after outbreak onset.Setting Population-based epidemiological study in Havelock North, New Zealand.Participants We enrolled notified CC cases with gastroenteritis symptom onsets 5 August 2016–6 September 2016 and conducted a telephone survey of households supplied by the contaminated water source to enrol PC and ND cases.Results One hundred and six (47.3%) CC, 47 (32.6%) PC and 113 (34.3%) ND cases completed the AReA telephone questionnaire. …”
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Increasing incidences and changes in treatment trends of clavicle fractures in adults during 2 decades in Denmark: a nationwide study on data from the Danish National Patient Regis... by Ida Tryggedsson, Bjarke Viberg, Per Hviid Gundtoft, Ilija Ban, Søren Overgaard, Tazio Maleitzke, Arvind von Keudell

“…Primary treatment was categorized as surgical if a relevant surgical procedure code was registered within 3 weeks of the fracture code, otherwise treatment was defined as non-surgical. …”
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A molecular toxicological study to explore potential health risks associated with ultrafine particle exposure in cold and humid indoor environments by Ziyu Shu, Shuo Qing, Xu Yang, Ping Ma, Yang Wu, Baizhan Li, Fangxin Fang, Runming Yao

“…Male Balb/c mice were exposed to specific concentrations of CB-NPs (30–50 nm in diameter, 0.184 mg/(kg·day)) in a controlled environmental chamber mimicking cold (10°C/14°C) and humid (90 % RH) conditions over three weeks. The results indicate that exposure to CB-NPs alone increased lung function, oxidative stress (ROS, GSH, MDA), inflammation (IL-6, TNF-α, IL-1β), apoptosis (Caspase 3, Caspase 8, Caspase 9), and histopathological alterations in lung tissue. …”
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Sensorimotor Robotic Measures of tDCS- and HD-tDCS-Enhanced Motor Learning in Children by Lauran Cole, Sean P. Dukelow, Adrianna Giuffre, Alberto Nettel-Aguirre, Megan J. Metzler, Adam Kirton

“…A KINARM robotic protocol quantifying proprioception, kinesthesia, visually guided reaching, and an object hit task was completed at baseline, posttraining, and six weeks later. Effects of the treatment group and training on changes in sensorimotor parameters were explored. …”
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Study protocol of a randomised controlled trial on SISU, a software agent providing a brief self-help intervention for adults with low psychological well-being by Harald Baumeister, Ann-Marie Küchler, David Ebert, Natalie Bauereiss, Eileen Bendig, Benjamin Erb, Lena Weger, Echo Meißner

“…Assessment takes place before (t1), during (t2) and after (t3) the interaction with SISU, as well as 4 weeks after randomisation (t4). Primary outcome is psychological well-being (WHO-5). …”
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Effects of dietary selenium nanoparticles, selenomethionine and sodium selenite on growth performance, levels of thyroid hormones and antioxidant status of rainbow trout, Oncorhync... by Fardin Shaluei, Somayeh Hadadi, Shafigh Shafiei, Hossein Rahimi, Mehrdad Fattollahi

“…Fish with an average weight of 29.25 ± 1.70 g were fed with experimental diets for 8 weeks. The fish were fed twice a day (at 9:00 AM and 2:00 PM) at the rate of 4% of their biomass.Results and discussion: The results showed that selenium nanoparticles had no significant effect on growth indices compared to organic and inorganic forms (p<0.05). …”
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The Accuracy and Precision of the Continuously Stored Data from Flash Glucose Monitoring System in Type 2 Diabetes Patients during Standard Meal Tolerance Test by Rengna Yan, Huiqin Li, Xiaocen Kong, Xiaofang Zhai, Maoyuan Chen, Yixuan Sun, Lei Ye, Xiaofei Su, Jianhua Ma

“…Venous blood glucose (VBG) was tested at 0, 30, 60, and 120 min after standard meal tests in one middle day of the first and second weeks, respectively. The corresponding sensor glucose values were obtained from interpolating continuously stored data points. …”
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Excessive copper induces lignin biosynthesis in the leaves and roots of two citrus species: Physiological, metabolomic and anatomical aspects by Xin Zhou, Xing Xiong, Fei Lu, Wenqing Shi, Yu Zhou, Ningwei Lai, Li-Song Chen, Zeng-Rong Huang

“…Osbeck, a more Cu-tolerant species] were treated with nutrient solution containing 0.5 (as Control), 100, 300 or 500 µM Cu for 15 weeks in sandy culture. By the end of treatments, citrus leaves and roots were sampled to investigate the biomass allocation, Cu distribution, the lignin biosynthesis and deposition. …”
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Modulation of Caecal Microbiome in Obese Mice Associated with Administration of Amaranth or Soybean Protein Isolates by Diana Olguín-Calderón, Jorge L. González-Escobar, Rosalva Ríos-Villa, Elena Dibildox-Alvarado, Antonio De León-Rodríguez, Ana P. Barba de la Rosa

“…Male C57BL/6 mice were fed for 8 weeks with regular (RD) or high-fat (HF) diet, without or with complementation with amaranth or soybean protein isolates. …”
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