DMAV in Drinking Water Activated NF-κB Signal Pathway and Increased TGF-β and IL-1β Expressions in Bladder Epithelial Cells of Rats by Siqi Cao, Shengnan Liu, Fei Wang, Jieyu Liu, Mengdan Li, Chen Wang, Shuhua Xi

“…In this study, we measured the expressions of mRNA and proteins of NF-κB pathway members, IKKα, IKKβ, p65, and p50 in rat bladder epithelium by qRT-PCR and immunohistochemical analysis after rats received drinking water containing 100 and 200 ppm DMAV for 10 weeks. Transforming growth factor-β (TGF-β) immunoexpression in rat bladder epithelium and urine level of IL-1β also were determined. …”
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Sex-specific association between maternal childhood adversities and offspring’s weight gain in a Brazilian cohort by Vinicius Oliveira Santana, Aline Camargo Ramos, Hugo Cogo-Moreira, Célia Maria Araújo, Barbara Shibuya Alves, Lucas Ribeiro, Aline Lodi, Ana Carolina Coelho Milani, Ivaldo Silva, Cristiane S. Duarte, Jonathan Posner, Andrea Parolin Jackowski

“…Anthropometric data (weight, length, head circumference) and other information (feeding type, offspring sex, family income) were collected at delivery (W0), discharge (W1), and up to 8 weeks postpartum (W2). ACEs were assessed using the CDC-Kaiser Questionnaire, and weight gain was calculated as the difference between W2 and W1, divided by the number of days between measurements. …”
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Swiss Orthopaedics Minimal Dataset: First Pilot Report of Reliability and Validity by Thorsten Jentzsch, Claudio Dora, Urs Müller, Mazda Farshad

“…It is a standardized, generic, and patient-reported outcome questionnaire, comprising ten items (location of disease, pain within the past four weeks, limitations at work/leisure/sleep/autonomy, subjective value of a body part, employment status, work disability (sick leave/pension), and household support). …”
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Correlation Analysis between GDM and Gut Microbial Composition in Late Pregnancy by Genxia Li, Pan Yin, Shuhui Chu, Wanli Gao, Shihong Cui, Shuhua Guo, Yajuan Xu, Enwu Yuan, Texuan Zhu, Jie You, Junya Zhang, Manman Yang

“…We sequenced the V3-V4 regions of the 16S ribosomal ribonucleic acid (rRNA) gene from stool samples of 52 singleton pregnant women at >28 weeks of gestation. Our results showed that there were significant differences between the NOR group vs. …”
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Intraoperative Local Administration of Platelet-Rich Plasma (PRP) during Neurolysis Surgery for the Treatment of Digital Nerve Crush Injury by Akira Ikumi, Yuki Hara, Eriko Okano, Sho Kohyama, Norihito Arai, Yu Taniguchi, Hisashi Sugaya, Tomokazu Yoshioka, Akihiro Kanamori, Masashi Yamazaki

“…In the current case report, intraoperative local administration of PRP was performed during neurolysis surgery for a healthy 28-year-old woman with digital nerve crush injury. Five weeks postinjury, surgery was performed due to severe uncontrollable neuropathic pain and no sensory nerve action potential derivation of the index finger. …”
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Promoting Optimal Physical Exercise for Life: An Exercise and Self-Management Program to Encourage Participation in Physical Activity after Discharge from Stroke Rehabilitation—A F... by Avril Mansfield, Svetlana Knorr, Vivien Poon, Elizabeth L. Inness, Laura Middleton, Louis Biasin, Karen Brunton, Jo-Anne Howe, Dina Brooks

“…Compliance with wearing an accelerometer for 6 weeks continuously and completing physical activity questionnaires was high (>80%), whereas only 34% of daily heart rate data were available. …”
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Trait mindfulness in early pregnancy and adverse perinatal outcomes: a prospective cohort study by Audra C. Fain, Tess E. K. Cersonsky, Margaret H. Bublitz, Adam K. Lewkowitz, Erika F. Werner, Emily S. Miller, Nina K. Ayala

“…Participants completed the validated Mindfulness and Attentive Awareness Scale prior to 20 weeks gestation. Trained research staff abstracted pregnancy and delivery data. …”
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Efficacy and safety of faricimab for neovascular age-related macular degeneration: a systematic review and network meta-analysis by Francisco Rodríguez, Daniel Samacá-Samacá, Claudia Hernández-Castillo, Laura Prieto-Pinto, Carolina Sardi, Hugo Ocampo, Joshua Kock, Fabián Hernández

“…Results also showed that more patients treated with faricimab were free from post-treatment retinal fluid compared with aflibercept every 8 weeks, and both ranibizumab and bevacizumab, in the fixed and pro re nata (PRN) assessed schedules. …”
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Associations Between Ambient PM_2.5 and Thyroid Hormones in Pregnant Persons in Puerto Rico by Trenton Honda, Trenton D. Henry, Laura Corlin, Kipruto Kirwa, Akram Alshawabkeh, Julia R. Varshavsky, Winston Kennedy, José F. Cordero, Carmen M. Velez Vega, Zaira Y. Rosario Pabon, John D. Meeker, Helen Suh

“…Pollution concentrations were linked to participant locations using EPA air quality data and analyzed across two visits during gestational weeks 16–20 and 24–28. Results: The results suggest that PM_2.5 exposure is positively associated with maternal T3, T4, and FT4 levels but not TSH. …”
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Scutellarin Attenuates Hypertension-Induced Expression of Brain Toll-Like Receptor 4/Nuclear Factor Kappa B by Xingyong Chen, Xiaogeng Shi, Xu Zhang, Huixin Lei, Simei Long, Huanxing Su, Zhong Pei, Ruxun Huang

“…This study aimed to investigate the effects of scutellarin (administered by oral gavage daily for 2 weeks) on brain TLR4/nuclear factor kappa B-(NF-κB-) mediated inflammation and blood pressure in renovascular hypertensive (using the 2-kidney, 2-clip method) rats. …”
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Wastewater-based estimation of temporal variation in shedding amount of influenza A virus and clinically identified cases using the PRESENS model by Hiroki Ando, Michio Murakami, Masaaki Kitajima, Kelly A. Reynolds

“…The model revealed that a 50 % probability of IAV detection in wastewater corresponds to 0.53 (95 % CrI: 0.35–0.78) cases per 100,000 people, as observed in clinical surveillance over two weeks. Next, we applied the previously developed PRESENS model to IAV wastewater concentration data from California, revealing rapid and prolonged virus shedding patterns. …”
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Maternal Vitamin D Status and Its Effect on Vitamin D Levels in Early Infancy in a Tertiary Care Centre in Sri Lanka by Kaneshapillai Anusha, Usha Hettiaratchi, Dulani Gunasekera, Shamini Prathapan, Guwani Liyanage

“…This prospective cohort study was conducted on 140 healthy pregnant mothers in the third trimester (mean gestational age 39±1 weeks). Blood was collected for 25(OH)D and parathyroid hormone (PTH). …”
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Sistem Deteksi Dini Penyakit Preeklampsia Melalui Perubahan Warna Urine Berdasarkan Protein dengan Menggunakan Metode Naïve Bayes Classifier by Fakhrul Allaam, Barlian Henryranu Prasetio, Rizal Maulana

“…This condition can usually occur in the 2nd and 3rd trimester of pregnancy or later 20 weeks. There are several ways to find out the disease, one of which is by looking at the condition of the urine. …”
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Wearable Activity Tracking Device Use in an Adolescent Weight Management Clinic: A Randomized Controlled Pilot Trial by Kanika Bowen-Jallow, Omar Nunez-Lopez, Alex Wright, Erika Fuchs, Mollie Ahn, Elizabeth Lyons, Daniel Jupiter, Lindsey Berry, Oscar Suman, Ravi S. Radhakrishnan, Andrea M. Glaser, Deborah I. Thompson

“…Differences between groups at 6, 12, and 18 weeks were examined. Results. Forty-eight participants were enrolled in the study. …”
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Low Citrate Synthase Activity Is Associated with Glucose Intolerance and Lipotoxicity by Yosra Alhindi, Lobke M. Vaanholt, Mustafah Al-Tarrah, Stuart R. Gray, John R. Speakman, Catherine Hambly, Bader S. Alanazi, Brendan M. Gabriel, Arimantas Lionikas, Aivaras Ratkevicius

“…C57BL/6J (B6) mice and congenic B6.A-(rs3676616-D10Utsw1)/KjnB6 (B6.A), a strain which carries the A/J allele of CS on the B6 strain background, were fed HFD (45% kcal from fat) for 12 weeks. C2C12 mouse muscle cells were used to investigate effects of CS knockdown on cell viability and signalling after incubation in 0.8 mM palmitate. …”
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Skeletal Muscle-Derived Stem/Progenitor Cells: A Potential Strategy for the Treatment of Acute Kidney Injury by Egle Pavyde, Romaldas Maciulaitis, Mykolas Mauricas, Gintaras Sudzius, Ernesta Ivanauskaite Didziokiene, Arvydas Laurinavicius, Neringa Sutkeviciene, Edgaras Stankevicius, Justinas Maciulaitis, Arvydas Usas

“…PKH-26-labeled MDSPCs were identified within renal cortex 1 and 2 weeks after cell administration, indicating MDSPCs capacity to migrate and populate renal tissue. …”
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Polydopamine grafting polyether ether ketone to stabilize growth factor for efficient osteonecrosis repair by Yi Sun, Jingyun Liu, Kaijia Chen, Nannan Zhong, Chengpeng He, Xinming Luan, Xiaobei Zang, Jianbo Sun, Ning Cao, Wenbo Wang, Qiang Ren

“…The experiments involved adult male New Zealand rabbits aged 24–28 weeks and weighing 2.6–4 kg. The SPEEK-PDA-BFP possesses the smallest water contact angle, indicating the highest hydrophilicity, with its surface characterized by a rich density of clustered BFP particles. …”
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Economic evaluation of pan-genotypic generic direct-acting antiviral regimens for treatment of chronic hepatitis C in Iran: a cost-effectiveness study by Seyed Moayed Alavian, Mohammad Tasavon Gholamhoseini, Heidar Sharafi, Helena HL Borba, Asma Sabermahani, Behzad Hajarizadeh

“…In sensitivity analysis, scenario 4 would be also cost-saving among people with no cirrhosis provided a 39% reduction in the cost of 12 weeks SOF/VEL.Conclusion Initiating all patients on pan-genotypic generic DAA regimens with no pretreatment genotyping was cost-effective compared with scenarios requiring pretreatment HCV genotype tests. …”
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Influence of Second-Trimester Ultrasound Markers for Down Syndrome in Pregnant Women of Advanced Maternal Age by Mariza Rumi Kataguiri, Edward Araujo Júnior, Luiz Claudio Silva Bussamra, Luciano Marcondes Machado Nardozza, Antonio Fernandes Moron

“…This was a retrospective cohort study on 889 singleton pregnancies between the 14th and 30th weeks, with maternal age ≥ 35 years, which would undergo genetic amniocentesis. …”
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H. Wendl Leaf Metabolites Potentiate the Radiosensitivity of Hepatocellular Carcinoma Through Ki67 and PARP Inhibition by Nabil M. Selim PhD, Seham S. El-Hawary PhD, Soheir M. El Zalabani PhD, Rehab Nabil Shamma PhD, Nariman El Sayed Mahdy PhD, Noheir H. Sherif PhD, Khayrya A. Youssif PhD, Usama Ramadan Abdelmohsen PhD, Mai H. Mekkawy PhD, Hanan A. Fahmy PhD

“…In the in vivo study, HCC was induced in male albino rats through administration of DEN in drinking water for 8 weeks, then treatment with NE (100 mg/kg) until the experiment’s ending. …”
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