The BET inhibitor JQ1 targets fat metabolism and counteracts obesity by Claudia Fornelli, Alessia Sofia Cento, Lorenzo Nevi, Raffaella Mastrocola, Gustavo Ferreira Alves, Giuseppina Caretti, Massimo Collino, Fabio Penna

“…Methods: Male C57BL/6J mice were divided in subgroups, either fed a standard diet or a high fat diet for 22 or 12 weeks, treated over the last 14 days with JQ1 or with vehicle. …”
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Assessment of effectiveness of oral supplementation of isolated fiber of carrot on metabolic parameters in mature rats by Maria Rosana Ramirez, Debora Manuale, Juan Carlos Yori

“…The groups were as follows: animals fed a standard diet, control group; high fiber supplementation (70 mg); low fiber supplementation (35 mg); for 12 weeks. Blood samples were collected at the time of sacrifice. …”
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Aggravating Effects of Psychological Stress on Ligature-Induced Periodontitis via the Involvement of Local Oxidative Damage and NF-κB Activation by Qiang Li, Yajuan Zhao, Daokun Deng, Jiuhui Yang, Yongjin Chen, Jia Liu, Min Zhang

“…Chronic unpredictable mild stress (CUMS) was used to establish psychological stress, and silk ligature was used to induce experimental periodontitis. Four weeks later, stressed rats showed altered behaviour, serum hormone levels, and sucrose preference. …”
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Association between incident falls and subsequent fractures in patients attending the fracture liaison service after an index fracture: a 3-year prospective observational cohort st... by Piet Geusens, Jacqueline R Center, Tuan V Nguyen, Thach Tran, Johanna Driessen, Joop P van den Bergh, John Eisman, Caroline E Wyers, Lisanne Vranken, Robert Y Van der Velde, Heinrich M J Janzing, Sjoerd Kaarsemakers, Dana Bliuc

“…Of the fractures, 47 (78.3%) were fall related, of which 25 (53.2%) were sustained at the first fall incident at a median of 34 weeks. An incident fall was associated with an approximately 9-fold (HR: 8.6, 95% CI 3.1 to 23.8) increase in the risk of subsequent fractures.Conclusion These data suggest that subsequent fractures among patients on treatment prescribed in an FLS setting are common, and that an incident fall is a strong predictor of subsequent fracture risk. …”
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Effects of a cardiopulmonary rehabilitation programme on submaximal exercise in Tunisian patients with long-COVID19: A randomized clinical trial by Rania Kaddoussi, Hadhemi Rejeb, Amine Kalai, Eya Zaara, Naceur Rouetbi, Zohra Ben Salah Frih, Piotr Zmijewski, Helmi Ben Saad

“…The CPRP (i.e. 18 sessions over six weeks) encompassed warm-up, aerobic training, resistance training, respiratory exercises, and therapeutic education. …”
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Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection by Nadine Rujeni, Norman Nausch, Nicholas Midzi, Graeme J. Cowan, Richard Burchmore, David R. Cavanagh, David W. Taylor, Takafira Mduluza, Francisca Mutapi

“…Antibody responses directed against schistosome antigens, Plasmodium falciparum crude and recombinant antigens, and the allergen house dust mite were measured in children aged 3 to 5 years before and 6 weeks after treatment. The change in serological recognition of schistosome proteins was also investigated. …”
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Simultaneous central retinal vein and cilioretinal artery occlusion in a young female patient with progestin-only oral contraceptive use: a case report by Sardar Noman Qayyum, Risha Naeem, Faraz Azhar, Gulmeena Aziz Khan, Tehreem Zubair, Samim Noori

“…She was treated with acetazolamide, aspirin, and ocular massage, alongside a dorzolamide-timolol combination for intraocular pressure control. Six weeks later, panretinal photocoagulation was performed to prevent neovascular complications. …”
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EEG electrode setup optimization using feature extraction techniques for neonatal sleep state classification by Hafza Ayesha Siddiqa, Muhammad Farrukh Qureshi, Arsalan Khurshid, Yan Xu, Laishuan Wang, Saadullah Farooq Abbasi, Chen Chen, Wei Chen

“…An 16,803 30-second segment was collected from 64 infants between 36 and 43 weeks of age at Fudan University Children's Hospital to train and test the proposed model. …”
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Evolution of the umbilical cord blood proteome across gestational development by Leena B. Mithal, Nicola Lancki, Ted Ling-Hu, Young Ah Goo, Sebastian Otero, Nathaniel J. Rhodes, Byoung-Kyu Cho, William A. Grobman, Judd F. Hultquist, Denise Scholtens, Karen K. Mestan, Patrick C. Seed

“…In this study, we comprehensively characterized the cord blood proteome of infants born between 25 to 42 weeks using untargeted mass spectrometry and functional enrichment analysis. …”
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Malaria exposure remodels the plasma proteome of Ghanaian children by Aisha M. Mohammed, Charles Ochieng’ Olwal, Andrea Fossati, Nancy K. Nyakoe, Jacqueline M. Fabius, Martin Gordon, Benjamin J. Polacco, Danielle L. Swaney, Gordon A. Awandare, Nevan J. Krogan, Mehdi Bouhaddou, Yaw Bediako

“…Methods Symptomatic children residing in high and low malaria transmission areas of Ghana were enrolled into the study and followed for 3 weeks from the day of malaria confirmation. The plasma proteome of these children was profiled using a mass spectrometry-based approach and putative protein-based biomarkers and predictors of immune tolerance to malaria were identified. …”
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Astigmatism and maternal myopia as important factors affecting success rate of DIMS lens treatment by Christof Meigen, Adrienne Csutak, Patricia Domsa, Éva M Bankó, Judit Körtvélyes, Rita Széchey, Krisztina Lantos, Zoltán Zsolt Nagy

“…Quality of life assessments were conducted at baseline, at 2 weeks, and 3, 6, 9 and 12 months. Additionally, parental myopic dioptre was recorded when applicable.Results At the 12-month mark, myopia progression in patients (mean±SE: −0.40±0.05) mirrored findings from prior European DIMS studies, but with 50% of patients showing no progression. …”
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An Innovation to Address the Anterior Pelvic Ring Disruptions by Ramesh Perumal, Harish Mahesan, Dheenadhayalan Jayaramaraju, Rajasekaran Shanmuganathan

“…Postoperative X-rays included AP, inlet, outlet, and lateral views and were reviewed at 4 and 12 weeks and 6 and 12 months for the evidence of loss of reduction, loosening of screws, hardware failure, and functional outcome (Majeed score). …”
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Physical fitness of young Greco-Roman athletes under the restrictions of the COVID-19 pandemic by Ruslan Rusanov, Leonid Vostroknutov, Shi Ke, Katarzyna Prusik, Julia Golenkova

“…The study was conducted for 12 weeks. At the beginning and at the end of the study, a final testing of the level of physical fitness of boys was carried out. …”
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Short-term outcomes of oropharyngeal administration of colostrum in preterm neonates: a double-blind placebocontrolled randomized trial by Ameneh Lamsehchi, Maryam Shokouhi Solgi, Mohammad Kazem Sabzehei, Behnaz Basiri, Elahe Talebi Ghane, Kiana Kimiaei Asadi, Sina Azadnajafabad

“…Results A total of 126 neonates (mean gestational age, 30.05 weeks) were randomized to the intervention and placebo groups (n=63 each) and had a mean±standard deviation weight of 1,247±193 g versus 1,156±215 g (P=0.013) and 1- and 5-min Apgar scores of 6.35 versus 5.38 (P=0.003) and 7.84 versus 7.13 (P=0.001), respectively. …”
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Using Micro-Learning to Enhance Knowledge and Skills of Airway Management in Nurse Anesthesia Students: An Interventional Study by Masoumeh Albooghobeish, Alireza Ghalandeh, Ali Khalafi, Mohammad Hosein Haghighizadeh

“…Participants were first assessed with a Pre-test, and then assigned to either the M-L M (n=26) or T M (n=26) groups. Over three weeks, the M-L M group received Micro-Learning-based materials through social media, while the T M group received traditional face-to-face instruction. …”
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Fructosamine measurement for diabetes mellitus diagnosis and monitoring: a systematic review and meta-analysis protocol by Andre Pascal Kengne, Eugene Sobngwi, Jean Jacques N Noubiap, Jobert Richie N Nansseu, Joël Fokom-Domgue, Eric V Balti

“…Introduction Fructosamine is a marker of glucose control reflecting the average glycaemic level over the preceding 2–3 weeks. Fructosamine has not gained as much popularity as glycated haemoglobin (HbA1c) for diabetes mellitus (DM) control monitoring, and the related underlying reasons remain unclear. …”
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Is Lateral Ligament Complex Repair Necessary in All Unstable Elbow Injuries with Coronoid Fractures? A Comparative Study: A Case Series by Nishaanth Ragavan, Rex Chandrabose

“…Functional outcome was assessed using the Mayo Elbow Performance Score (MEPS) at 6 weeks, 3rd, 6th months, 1, and 2 years. Results: All patients in our study were treated surgically according to Wrightington's classification. …”
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Salivary Biomarkers (Opiorphin, Cortisol, Amylase, and IgA) Related to Age, Sex, and Stress Perception in a Prospective Cohort of Healthy Schoolchildren by Anna Krahel, Elzbieta Paszynska, Justyna Otulakowska-Skrzynska, Szymon Rzatowski, Amadeusz Hernik, Agnieszka Slopien, Tomasz Hanć, Paula Szczesniewska, Ewa Bryl, Yves Boucher, Marta Tyszkiewicz-Nwafor, Maria Gawriolek, Monika Dmitrzak-Weglarz

“…However, OPI levels were higher and correlated to prior stress exposure in children (0.31±0.4 vs. 0.26±0.5 ng/mL, p=0.031). sAA was negatively correlated to low mood self-declaration in children in the last two weeks (r=−0.10, p=0.045). Conclusions. sIgA and sAA can be used as sex- and age-related biomarkers in children 6-12 y.o., which is not the case for free cortisol and opiorphin. …”
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Immunogenicity of Two Fractional Inactivated Poliovirus Vaccine Doses vs Single Intramuscular Inactivated Poliovirus Vaccine Dose in Infants of Low- and Middle-income Countries: A... by Kunal Kumar, Sangita Yadav, Raghvendra Singh, Archana Thakur

“…Seroconversion was described as a fourfold rise in antibody titers after 4 weeks. Results: Pre- and postimmunization mean antibody titers (MAT) in pg/mL against types I, II, and III PVs in the ID group were 192.26 ± 49.5, 162.96 ± 34.1, 131.32 ± 38.4, and 1743.58 ± 391.6, 1272.10 ± 341.3, 1105.71 ± 331.1, respectively. …”
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Effects of anti-CD4 antibody treatment on calcium ions influx in peanut-sensitized C3H/HeJ mice by Junjuan Wang, Cui Zhou, Shiwen Han, Zainabu Majid, Na Sun, Huilian Che

“…C3H/HeJ mice sensitized with peanut protein extract (PPE) were injected with anti-CD4 antibodies for 4 weeks. Stimulation with PPE increased the specific immunoglobulin (IgE), cytokine, histamine, and mMcp-1 levels, upregulated decorin (Dcn) expression, induced Ca2+ inflow in the spleen, and augmented the expression of the transcription factors GATA-3 and Foxp3, which resulted in Th2 and Treg cell activation. …”
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