On the space of SARS-CoV-2 genetic sequence variants by A. Yu. Palyanov, N. V. Palyanova

“…We have developed software capable of loading and analyzing SARS-CoV-2 nucleotide sequences in FASTA format, determining the 5’ and 3’ UTR positions, the number and location of unidentified nucleotides (“N”), performing alignment with the reference sequence by calling the program designed for this, determining mutations, deletions and insertions, as well as calculating various characteris tics of virus genomes with a given time step (days, weeks, months, etc.). The data obtained indicate that, despite the apparent mathematical diversity of possible options for changing the virus over time, the corridor of the evolutionary  trajectory that the coronavirus has passed through seems to be quite narrow. …”
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Probiotics alleviate painful diabetic neuropathy by modulating the microbiota–gut–nerve axis in rats by Ye Jiang, Jing Yang, Min Wei, Jiayin Shou, Shixiong Shen, Zhuoying Yu, Zixian Zhang, Jie Cai, Yanhan Lyu, Dongsheng Yang, Yongzheng Han, Jinpiao Zhu, Zhigang Liu, Daqing Ma, Guo-gang Xing, Min Li

“…Supplementation with multiple probiotics for 12 weeks alleviated pain, reversed nerve fiber lesions, and restored neuronal hyperexcitability. …”
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Evaluation of Consumption of Poultry Products Enriched with Omega-3 Fatty Acids in Anthropometric, Biochemical, and Cardiovascular Parameters by José Arias-Rico, Martha Izbeth Cerón-Sandoval, Eli Mireya Sandoval-Gallegos, Esther Ramírez-Moreno, Trinidad Lorena Fernández-Cortés, Judith Jaimez-Ordaz, Elizabeth Contreras-López, Javier Añorve-Morga

“…To evaluate the effect of the consumption of poultry products supplemented with omega-3 in healthy population, a phase 1, double blind randomized, controlled parallel-group trial was carried out. After 14 weeks, the supplemented group had an increase in HDL, reducing the atherogenic index. …”
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Investigation of PACAP Fragments and Related Peptides in Chronic Retinal Hypoperfusion by Dora Werling, Dora Reglodi, Peter Kiss, Gabor Toth, Krisztina Szabadfi, Andrea Tamas, Zsolt Biro, Tamas Atlasz

“…Routine histology was performed 2 weeks after the surgery; cells were counted and the thickness of retinal layers was compared. …”
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AI-Enhanced Healthcare: Integrating ChatGPT-4 in ePROs for Improved Oncology Care and Decision-Making: A Pilot Evaluation by Chihying Liao, Chinnan Chu, Mingyu Lien, Yaochung Wu, Tihao Wang

“…Methods: Thirty cancer patients were consecutively collected via a web-based ePRO platform, reporting side effects over 4 weeks. ChatGPT-4, simulating oncologists, dietitians, and nurses, analyzed this data and offered improvement suggestions, which were then reviewed by professionals in those fields. …”
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Radio-protective effects of ultra-fine bubble hydrogen water and serum protein responses in whole-body radiation-exposed mice by Masaru Yamaguchi, Khin Thandar Htun, Youta Tatara, Yoshiaki Sato, Masato Hosoda, Suchart Kothan, Chikashi Kamimura, Osamu Inanami, Ikuo Kashiwakura

“…In the case of WBI with 6.5 Gy (lethal dose), while the control mice died out in about 3 weeks, the 30-day survival rate improved to 40% by UBHW due to the high scavenging activity of hydroxy radicals. …”
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Early Electrophysiological Disintegration of Hippocampal Neural Networks in a Novel Locus Coeruleus Tau-Seeding Mouse Model of Alzheimer’s Disease by A. Ahnaou, C. Walsh, N. V. Manyakov, S. A. Youssef, W. H. Drinkenburg

“…Here, a tau-seeding model in which preformed synthetic tau fibrils (K18) were unilaterally injected into the LC of P301L mice, equipped with multichannel electrodes for recording EEG in frontal cortical and CA1-CA3 hippocampal areas, was used to longitudinally quantify over 20 weeks of functional network dynamics in (1) power spectra; (2) FC using intra- and intersite phase-amplitude theta-gamma coupling (PAC); (3) coherence, partial coherence, and global coherent network efficiency (Eglob) estimates; and (4) the directionality of functional connectivity using extended partial direct coherence (PDC). …”
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Urban fruit bats give birth earlier in the season compared to rural fruit bats by Maya Weinberg, Dean Zigdon, Mor Taub, Lee Harten, Ofri Eitan, Adi Rachum, Reut Assa, Omri Gal, Yossi Yovel

“…Indeed, we found that urban fruit bats gave birth ~ 2.5 weeks earlier in spring than rural fruit bats. We also found that roosting in urban colonies did not decrease the bats’ reproductive success, in contrast to what has been suggested for some urban birds. …”
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Ameliorated Impact of Fenugreek Seed Extract on Some Blood Cellular and Biochemical Parameters in Female Albino Rats Exposed to Lead Acetate by Rozhya Abduljalil Naser, Rabar Yousif Mameik, Nazar M. Shareef Mahmood, Kurdo Bapir Chato

“…Rat’s administration was continued daily for two weeks respectively. The administration of rats with LA produced significant reduction in liver weight, food intake, while it increased triglyceride (TG), alkaline phosphatase (ALP), aspartate aminotransferase (AST), uric acid (UA) and creatinie (CR). …”
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The prevalence of thiamine deficiency among elderly nursing home residents: A cross‐sectional study by Nozomu Uchida, Mayumi Ishida, Izumi Sato, Akira Yoshioka, Takao Takahashi, Daisuke Furuya, Yasuhiro Ebihara, Hiroshi Ito, Hideki Onishi

“…Basic data (age, sex, height, weight, and BMI), dietary intake for the previous 3 weeks, degree of care (DOC), degree of independence in daily life for elderly with dementia (DIDLED), and comorbidities were analyzed using descriptive statistical methods. …”
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Optimizing Nitrogen Sources in Top Dressing for Wheat: Field Study on Growth, Yield, and Ammonia Volatilization by Muhammad Sajid Farooq, Rashid Mahmood, Aaqib Hameed, Sajid Ali, Faisal Nadeem, Tahir Hussain Awan, Ammara Fatima, Zaira Ahmad

“…Ammonia volatilization losses were tracked for up to 12 weeks from sowing. Ammonia losses from basal-applied N remained consistent in both years, comprising around 4% of the applied N. …”
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Evaluation of Epstein-Barr Virus Latent Membrane Protein 2 Specific T-Cell Receptors Driven by T-Cell Specific Promoters Using Lentiviral Vector by Dongchang Yang, Qing Shao, Hua Sun, Xiaoxin Mu, Yun Gao, Runqiu Jiang, Jiajie Hou, Kun Yao, Yun Chen, Beicheng Sun

“…Vectors containing Vβ 6.7 promoter were found to be optimal for expression in PBMCs, and they maintained expression of the transduced TCRs for up to 7 weeks. These cells had the potential to recognize subdominant EBV latency antigens as measured by cytotoxicity and IFN-γ secretion. …”
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Examining the etiology and pregnancy outcomes of 152 critically ill pregnant patients in the Intensive Care Unit by Weiman Liu, Junyou Su, Sumei Wang

“…Furthermore, the incidence of pregnancy termination and induced abortion before 28 weeks in the group affected by non-obstetric factors was significantly higher than that in the group affected by obstetric factors (all p < 0.05). …”
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Research of temperature destruction effect on cables insulation operation life by V. N. Pugach, D. A. Polyakov, K. I. Nikitin, N. A. Tereshchenko, I. V. Komarov

“…Experimental studies of cable insulation temperature monitoring have been carried out. Seven weeks of the experiment show an insignificant temperature change. …”
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Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy by Yi Cui, Li Wang, Wentao Liang, Li Huang, Shuting Zhuang, Hong Shi, Nuo Xu, Jianzhang Hu

“…Methods. After sixteen weeks of streptozocin intraperitoneal injection, corneal epithelium from three diabetic rats and three normal groups underwent whole-transcriptome sequencing. …”
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Ultrasound Presentation of a Disseminated Fetal and Neonatal Rhabdoid Tumor by Yolaine Joueidi, Aline Rousselin, Céline Rozel, Philippe Loget, Dominique Ranchere Vince, Sylvie Odent, Franck Bourdeaut, Vincent Lavoue, Maela Le Lous

“…This is a case report of a disseminated fetal rhabdoid tumor discovered at 32 weeks of gestation in a 29-year-old woman on immunosuppressive therapy. …”
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Effect of Repeated Remote Ischemic Preconditioning on Peripheral Arterial Disease in Patients Suffering from Intermittent Claudication by Mehmet Balin, Tarık Kıvrak

“…Patients received 5-cycles of alternating 5-minute inflation and 5-minute deflation of blood-pressure cuffs on nondominant upper-limb every day for four weeks. Initial claudication distance (ICD), total walking distance (TWD) and time to relief of claudication (TRC) were recorded during procedure. …”
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The Validity Of 75gms OGTT For Detection Of GDM Keeping 100gms OGTT As Gold Standard by Shazia Mehreen, Muhammad Usman, Kashif Rauf, Saima Naz, Muhammad Abdul Rab Faisal Sultan, Muhammad Akram Randhawa

“…All pregnant women underwent a 75g oral glucose test in the 2nd trimester at 24-28 weeks of gestation. For this, the patients were sent to the MCH laboratory with overnight fasting where FBS was taken and they were given a 75 g glucose drink. …”
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Species diversity of saprophagous flies (Diptera) in hospital grounds of Tehran, Iran by Abbas Ali Mirzakhanlou, Mansoureh Shayeghi, Hassan Vatandoust, Arman Izadian, Zahra Karimi, Kamran Akbarzadeh

“…The sampling process for this cross-sectional study was carried out every two weeks on the grounds of four hospitals in Tehran, using bottle traps and insect nets from March 2020 to February 2021. …”
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Comparing the effectiveness of different exercise interventions on quality of life in stroke patients: a randomized controlled network meta-analysis by Liqun Jiang, Huimin Ding, Qishuai Ma, Shang Gao, Xinxin Zhang, Buongo Chun

“…Participants aged 50–70 underwent interventions lasting 3 weeks to 6 months. DTOT (Dual-task oriented training)was most effective for Quality of Life, Mental Health, and Upper Limb Function; AQE (Aquatic Exercise) for Physical Health and Social Participation; ST(Strength Training) for Pain and Vitality; CIT(Constraint-Induced Therapy) for Mobility and Recovery; BCT for Memory and Thinking; ALCE(Aquatic and Land Combined Exercise) for Emotion and ADL; and ULT(Upper Limb Training) for Communication. …”
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