Conditional knockdown of hepatic PCSK9 ameliorates high-fat diet-induced liver inflammation in mice by Xue-Ying Zhang, Qing-Qing Lu, Yan-Jie Li, Shan-Rui Shi, Chao-Nan Ma, Miao Miao, Shou-Dong Guo

“…These mice were fed with a high-fat diet for 9 weeks to induce inflammation. The effects of conditional knockdown of hepatic PCSK9 on inflammation and the underlying mechanisms were investigated by molecular biological techniques. …”
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Comparative Characterization of Trends and Patterns of Physical and Chemical Attributes of Optimal and Traditional Processed Cowpea Leaves by Joshua Ombaka Owade, George Ooko Abong’, Michael Wandayi Okoth, Agnes Wakesho Mwang’ombe

“…With factor analysis determining optimal nutritional quality for cowpea leaves at 8 weeks after emergence, sun drying had the highest loss of beta-carotene and ascorbic acid, 66.7–80.1% and 53.7%–58.3%, respectively (p<0.001), whereas mineral leaching, reduction of antinutrients, and colour changes were more pronounced in dehydration techniques incorporating fermentation as pretreatment. …”
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Intensity-Modulated Radiotherapy for a Rendu-Osler-Weber Disease Patient with Recurrent Severe Epistaxis: A Case Report by Maximilian Niyazi, Marco-Domenico Caversaccio, Patrick Dubach, Andreas Geretschläger, Andreas Arnold, Claus Belka, Daniel M. Aebersold, Norbert M. Blumstein

“…The therapy was very well tolerated, no acute toxicities occurred. Two weeks after the last radiation dose had been applied, the nasal dressing could be removed without problems. …”
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The Influence of Mode-of-Injury on Psychological Readiness for Return-To-Sport Following Anterior Cruciate Ligament Reconstruction: A Matched-Controlled Study by Jenifer Presley, Lane Bailey, Kevin Maloney, Brian Duncan, Mathew Reid, Christopher Juneau, Walter R Lowe

“…Psychological readiness was examined 16-weeks postoperatively using the ACL-Return to Sport after Injury (ACL-RSI) questionnaire with subgroup analyses for the ‘emotional’, ‘confidence’ and ‘injury-risk’ subscales. …”
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A rare case of Ewing's sarcoma in a 4-year-old child treated by tumor endoprosthetics using 3D printing by Vladimir Stavrev, Luben Stokov, Petko Ganev, Georgi Georgiev

“…Results: The postoperative period was uneventful, with sutures removed on the 12th postoperative day. For 3 weeks, a tutor orthosis was placed. Active physiotherapy was started after removal of the orthosis 21 days after surgery. …”
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Effects of Microstructured and Anti-Inflammatory-Coated Cochlear Implant Electrodes on Fibrous Tissue Growth and Neuronal Survival by Lennart Fibranz, Wiebke Behrends, Katharina Wulf, Stefan Raggl, Lisa Kötter, Thomas Eickner, Soeren Schilp, Thomas Lenarz, Gerrit Paasche

“…Three groups of six guinea pigs each (control, structure, structure with diclofenac in the coating) were implanted for four weeks. The hearing thresholds were measured before implantation and after 28 days, and impedances were monitored over time. …”
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Terminalia catappa Extract Palliates Redox Imbalance and Inflammation in Diabetic Rats by Upregulating Nrf-2 Gene by Franklyn Nonso Iheagwam, Gaber El-Saber Batiha, Olubanke Olujoke Ogunlana, Shalom Nwodo Chinedu

“…Experimental rats were treated orally with 400 and 800 mg/kg bw TCA daily for four weeks. Antioxidant enzyme activities, plasma glucose concentration, protein concentration, oxidative stress, and inflammation biomarkers were assayed using standard methods. …”
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Models of provider care in long-term care: A rapid scoping review. by Candyce Hamel, Chantelle Garritty, Mona Hersi, Claire Butler, Leila Esmaeilisaraji, Danielle Rice, Sharon Straus, Becky Skidmore, Brian Hutton

“…<h4>Methods</h4>We conducted this review over 10-weeks of English language, peer-reviewed studies published from 2010 onward. …”
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Eales&rsquo; Disease in Inuit: A Short Report and Clinical Update by Forshaw TRJ, Moldow B

“…The right eye was treated in outpatients with sectoral laser photocoagulation. At seven weeks’ follow-up, the visual acuity had improved from 6/12 to 6/6 (right eye) and from 6/36 to 6/7.5 (left eye).Conclusion: The prevalence of tuberculosis in Greenland is very high and it is recommended that clinicians remain alert to the possibility of Eales’ disease, as beneficial visual outcomes are associated with prompt diagnosis and treatment. …”
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Chronic C-Type Natriuretic Peptide Infusion Attenuates Angiotensin II-Induced Myocardial Superoxide Production and Cardiac Remodeling by Yasuhiro Izumiya, Satoshi Araki, Hiroki Usuku, Taku Rokutanda, Shinsuke Hanatani, Hisao Ogawa

“…Simultaneously with the initiation of Ang II treatment, mice were infused with CNP (0.05 μg/kg/min) or vehicle for 2 weeks. The heart weight to tibial length ratio was significantly increased by Ang II in vehicle-treated mice. …”
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Phenolic-Rich Baccaurea angulata Modulates Inflammatory Biomarkers of Atherosclerosis by Muhammad Ibrahim, Maryam Abimbola Mikail, Idris Adewale Ahmed, Radiah Abdul Ghani

“…Group CH was fed 1% cholesterol diet only, group C1 was fed 1% cholesterol diet and 0.5 ml/kg/day B. angulata WF juice, group C2 was fed 1% cholesterol diet and 1.0 ml/kg/day B. angulata WF juice, group C3 was fed 1% cholesterol diet and 1.5 ml/kg/day B. angulata WF juice, group N was fed standard pellet only, group N1 was fed standard pellet and 0.5 ml/kg/day B. angulata WF juice, and group N2 was fed standard pellet and 1.0 ml/kg/day B. angulata WF juice for 12 weeks. Results. The administration of the various juices reduced the concentrations of induced serum inflammatory biomarkers. …”
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Analysis of the Renal Protection and Antioxidative Stress Effects of Panax notoginseng Saponins in Diabetic Nephropathy Mice by Wei Mi, Min Yu, Shuying Yin, Yuhan Ji, Tala Shi, Ning Li

“…A DN mouse model was constructed, and then low, medium, and high doses of PNS were used to intervene the model group mice. Eight weeks after intervention, the 24 h urine protein (UPro) and urinary albumin (UAlb) were quantitatively examined, and the related blood biochemical indices were measured. …”
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E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model by Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Nga T. Le, Carlos T. Huerta, Francesca A. Voza, Hongwei Shao, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Omaida C. Velazquez

“…After three postoperative weeks, hindlimb muscle was harvested for immunofluorescence analysis. …”
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The Association between Intertwin Difference in First Trimester Crown-Rump Length, Nuchal Translucency, and Birth Weight Discordance in Twin Pregnancies: A Retrospective Cohort Stu... by Zachary Michael Ferraro, Tinghua Zhang, Felipe Moretti, Karen Fung-Kee-Fung

“…Although intertwin CRL and NT discordance measured via ultrasound between 11-14 weeks gestation are related to birth weight discordance, there is uncertainty as to whether twin birth weight differences are related to adverse pregnancy outcomes in this population.…”
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Serum IL-1β, IL-2, and IL-6 in Insulin-Dependent Diabetic Children by Yasar Dogan, Saadet Akarsu, Bilal Ustundag, Erdal Yilmaz, Metin Kaya Gurgoze

“…Children with IDDM were divided into three subgroups: (1) previously diagnosed patients (long standing IDDM) (n:15), (2) newly diagnosed patients with diabetic ketoacidosis (before treatment) (n:12), and (3) newly diagnosed patients with diabetic ketoacidosis (after treatment for two weeks) (n:12). In all stages of diabetes higher levels of IL-1β and TNF-α and lower levels of IL-2 and IL-6 were detected. …”
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Ascertaining the Effectiveness of Coordination Training Interventions in Enhancing Sports Performance: A Systematic Review and Meta-analysis by Ashwani Saini, Bipin Kumar Dubey, Rakesh Vishwakarma

“…The studies included were confined to different coordination interventions, such as balance, rhythm, agility, neuromuscular training, jump ropeladder exercises, spatial orientation, non-sports specific and proprioceptive training, ranging from 6 weeks to an annual macrocycle with participants (sub-junior and junior levels) from different sports. …”
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Exercise-Induced Adaptations to the Mouse Striatal Adenosine System by Ella E. Bauer, Trevor J. Buhr, Carter H. Reed, Peter J. Clark

“…The results suggest that eight weeks of running wheel access spared age-related increases of A1R and A2AR protein concentrations across the dorsal and ventral striatal structures. …”
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Cumulative Incidence of Revision for a Balanced Knee System at a Mean 8-Year Follow-Up: A Retrospective Review of 500 Consecutive Total Knee Arthroplasties by Michael H. Bourne, Tony L. Miller, E. Marc Mariani

“…Follow-up was performed at 6 weeks, 6 months, 1 year, 5 years, and 10 years. 48 patients (9.6%) were considered lost to follow-up. …”
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Ameliorative Potential of Tamarindus indica on High Fat Diet Induced Nonalcoholic Fatty Liver Disease in Rats by Suja Rani Sasidharan, Joshua Allan Joseph, Senthilkumar Anandakumar, Vijayabalaji Venkatesan, Chandrasekharan Nair Ariyattu Madhavan, Amit Agarwal

“…The present study evaluated the ameliorative effect of extract of Tamarindus indica seed coat (ETS) on high fat diet (HFD) induced NAFLD, after daily administration at 45, 90, and 180 mg/kg body weight dose levels for a period of 6 weeks, in albino Wistar rats. Treatment with ETS at all tested dose levels significantly attenuated the pathological alterations associated with HFD induced NAFLD viz. hepatomegaly, elevated hepatic lipid and lipid peroxides, serum alanine aminotransferase, and free fatty acid levels as well as micro-/macrohepatic steatosis. …”
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An Exploratory Study of Training Intensity in EEG Neurofeedback by Inês Esteves, Wenya Nan, Cristiana Alves, Alexandre Calapez, Fernando Melício, Agostinho Rosa

“…Nine participants in the INTENSIVE group completed 4 sessions with 37.5 minutes each during consecutive days, while nine participants in the SPARSE group performed 6 sessions of 25 minutes spread over approximately 3 weeks. As a result, regarding the short-term effects, the upper alpha band amplitude change within sessions did not significantly differ between the two groups. …”
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