A rapid method for the preparation of an in vitro osteoporosis model of calf vertebrae: histological and biomechanical study by Anli Shi, Anli Shi, Yijie Liu, Qiang Ma, Jiaxin Li, Jiawang Fan, Zhaohui Ge, Zhaohui Ge

“…Given the constraints of limited supply and high costs associated with human specimens, calf spines are frequently employed as surrogates for human spines in both in vivo and in vitro biomechanical studies.MethodsThis study selected 60 spinal vertebrae from calves aged between 12 and 18 weeks. The specimens were randomly assigned to two treatment groups, A and B, each comprising 30 specimens. …”
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Whipple’s Disease: Our Own Experience and Review of the Literature by Jan Bureš, Marcela Kopáčová, Tomáš Douda, Jolana Bártová, Jan Tomš, Stanislav Rejchrt, Ilja Tachecí

“…Patients were treated using i.v. penicillin G or amoxicillin-clavulanic acid + i.v. gentamicin for two weeks, followed by p.o. doxycycline (100 mg per day) plus p.o. salazopyrine (3 g per day) for 1 year. …”
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The Clinical Utility of the Seated Wall Angel as a Test with Scoring by Chad Kofoed, Allison Palmsten, Jonathon Diercks, Michael Obermeier, Marc Tompkins, Terese L Chmielewski

“…Testing occurred after physical therapy examination (initial) and six weeks later (follow-up). Rehabilitation was not controlled. …”
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Effects of Pioglitazone on Asymmetric Dimethylarginine and Components of the Metabolic Syndrome in Nondiabetic Patients (EPICAMP Study): A Double-Blind, Randomized Clinical Trial by Pedram Shokouh, Adel Joharimoghadam, Hamidreza Roohafza, Masoumeh Sadeghi, Allahyar Golabchi, Maryam Boshtam, Nizal Sarrafzadegan

“…The present trial aimed to investigate the effects of pioglitazone on the serum level of asymmetric dimethylarginine (ADMA), a marker of endothelial function, and some indices of inflammation and glucose and lipid metabolism in nondiabetic metabolic syndrome patients. 104 eligible participants (57% female; age between 20 and 70) were enrolled in a double-blind placebo-controlled trial and were randomized to receive either pioglitazone (uptitrated to 30 mg/day) or matching placebo for 24 weeks. Participants were clinically examined and a blood sample was obtained at baseline and at the end of the trial. …”
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Heart-Derived Stem Cells in Miniature Swine with Coronary Microembolization: Novel Ischemic Cardiomyopathy Model to Assess the Efficacy of Cell-Based Therapy by Gen Suzuki, Rebeccah F. Young, Merced M. Leiker, Takayuki Suzuki

“…At 2 months after embolization, animals (n=11) were randomized to receive allogeneic cardiosphere-derived cells derived from atrium (CDCs: 20 × 106, n=5) or saline (untreated, n=6). Four weeks after therapy myocardial function, myocyte proliferation (Ki67), mitosis (phosphor-Histone H3; pHH3), apoptosis, infarct size (TTC), myocyte nuclear density, and cell size were evaluated. …”
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Factor Analysis and Mental Health Prevention of Employee Turnover under the Profit-Centered Development of Modern Service Industry by Youwen Zhong, Huifang Zhang, Xiaoling Wu

“…Therefore, through 12 weeks of standard dance practice, all psychological indicators of the experimental group are significantly improved. …”
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Comparison of linear mixed models for genetic feather score analysis in laying hens kept in recurrent testing facilities by T. Osorio-Gallardo, P. Bijma

“…This study compared and validated six models for genetic analysis of feather scores in the back and neck regions of laying hens at 45 and 70 weeks of age. We tested univariate models of feather score along with bivariate models for feather score and survival, and both sire and animal models, using individual or cage-level records. …”
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Wild-type bone marrow cells repopulate tissue resident macrophages and reverse the impacts of homozygous CSF1R mutation. by Dylan Carter-Cusack, Stephen Huang, Sahar Keshvari, Omkar Patkar, Anuj Sehgal, Rachel Allavena, Robert A J Byrne, B Paul Morgan, Stephen J Bush, Kim M Summers, Katharine M Irvine, David A Hume

“…Their loss in Csf1rko rats was confirmed by immunohistochemical localisation of CD209B (SIGNR1). By 6-12 weeks, Csf1rko rats succumb to emphysema-like pathology associated with the selective loss of interstitial macrophages and granulocytosis. …”
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Effects of organic amendment on some soil physicochemical characteristics and vegetative properties of Zea mays in wetland soils of the Niger Delta impacted with crude oil by Francis E. Egobueze, Josiah M. Ayotamuno, Chukwujindu M. A. Iwegbue, Chibogwu Eze, Reuben N. Okparanma

“…Results The total organic carbon (TOC) and pH increased significantly within the first 2 weeks after crude oil contamination; thereafter, the pH of the soil decreased significantly over incubation time, while there was steady increase in TOC with incubation time. …”
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Temporal changes of tibial eminence after bi-cruciate retaining total knee arthroplasty by Hiroshi Inui, Ryota Yamagami, Kenichi Kono, Kohei Kawaguchi, Kazuo Saita, Shuji Taketomi, Sakae Tanaka

“…Radiographs taken at 2 weeks postoperatively and at an average follow-up of 3.2 years were used to assess the tibial eminence. …”
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Exploratory study on the efficacy of topical pan-JAK inhibitor in ocular and skin GVHD in a sclerodermatous GVHD mouse model by Shinri Sato, Yoko Ogawa, Kazuki Asai, Eisuke Shimizu, Shota Shimizu, Hiroko Taniguchi, Takahiro Okazaki, Shigeto Shimmura, Kazuno Negishi, Masatoshi Hirayama

“…GVHD mice were treated with delgocitinib eye drops or ointment with samples analyzed at 4 weeks post-BMT. Topical delgocitinib ointment and eye-drop administration significantly increased the meibomian gland (MG) area and attenuated corneal epithelial damage. …”
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What about physician wellness? Impact of a quality improvement intervention by Pamela Mathura, Isabella Pascheto, Jennifer Ringrose, Gillian Ramsay

“…Additionally, there was a 23% reduction in the likelihood of needing to reduce clinical teaching unit service weeks.Conclusion When conducting QI initiatives, consider measuring the wellness of physicians and other healthcare providers. …”
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Association of CYP2C9∗3 and CYP2C8∗3 Non-Functional Alleles with Ibuprofen-Induced Upper Gastrointestinal Toxicity in a Saudi Patient by Amina M. Bagher

“…We presented a case of a 31-year-old Saudi female patient with a history of rheumatoid arthritis (RA) who had taken ibuprofen at 600 mg twice daily for eight weeks. The patient presented to the emergency department with symptoms including nausea, vomiting, severe abdominal pain, and black tarry stools. …”
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Vascularization of Nanohydroxyapatite/Collagen/Poly(L-lactic acid) Composites by Implanting Intramuscularly In Vivo by Hai Wang, Xiao Chang, Guixing Qiu, Fuzhai Cui, Xisheng Weng, Baozhong Zhang, Xiaojie Lian, Zhihong Wu

“…Composites were implanted intramuscularly in the groins of rabbits for 2, 6, or 10 weeks (n=5×3). After removing, the macroscopic results showed that there were lots of rich blood supply tissues embracing the composites, and the volumes of tissue were increasing as time goes on. …”
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Study on perspective taking in online discussions among university students with hearing impairments by A. A. Gareyev, Yu. V. Krasavina, E. P. Ponomarenko, A. A. Shishkina

“…The experiment involved 17 students, consisting of 8 Deaf and Hard of Hearing (DHH) students and 9 hearing students, who participated in online discussions via Telegram chats over a period of six weeks. Within the framework of the chosen qualimetric approach, methods of group expert assessments and a pedagogical council were employed, along with elements of quantitative content analysis. …”
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Enhancing work life through social cognition: the effect of SCIT in bipolar disorder by Zeynep Anaforoglu Bikmaz, Zeynep Mackali, Sibel Cakir

“…The effects of SCIT intervention with standard treatment methods were investigated on social cognition and functioning effects, which are often negatively affected in patients with BD-I.MethodsThe research involved 28 participants, allocated into two groups: An experimental group (n = 12) receiving SCIT for 8 weeks alongside standard treatments (pharmacotherapy and psychiatric interviews), and a control group (n = 16) undergoing standard treatment without additional interventions. …”
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Urothelial Differentiation of Human Umbilical Cord-Derived Mesenchymal Stromal Cells In Vitro by Shuai Wu, Zhongliang Cheng, Guohua Liu, Xinfeng Zhao, Liang Zhong, Yingjian Zhu, Jiang Zhu

“…During culture, hUCMSCs started to express UPII and cytokeratins weakly at 7 days and were significantly up-regulated at 2 weeks post-induction. Additionally, morphology of hUCMSCs changed from spindle-shape to a polygonal epithelial-shape similar to that of urothelial cells after 7 days. …”
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Co-creation of a toolkit to assist risk communication and clinical decision-making in severe preeclampsia: SPOT-Impact study design by Hannah Brown Amoakoh, Bregje C. De Kok, Linda Lucy Yevoo, Klaartje M. Olde Loohuis, Emmanuel K. Srofenyoh, Daniel K. Arhinful, Koiwah Koi-Larbi, Kwame Adu-Bonsaffoh, Mary Amoakoh-Coleman, Joyce L. Browne

“…The burden of adverse maternal and perinatal outcomes is particularly high for women who develop a hypertensive disorder remote from term (<34 weeks). In parallel, many women have a suboptimal experience of care. …”
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Comparison Of Maternal And Perinatal Outcome Of Isolated Borderline Amniotic Fluid Index Versus Normal Amniotic Fluid In Low-Risk Pregnancies At Term by Shabana Kalsoom, Noreen Majeed Majeed, Mamoona Riaz, Mehreen Mehdi, Khair-un-Nisa Asif, Iram Mushtaq

“…Group A had 180 women with borderline AFI having normal umbilical artery Doppler and group B had 360 women with normal AFI between 37-40 weeks, who fulfilled the inclusion criteria. The data regarding baseline characteristics and fetomaternal outcome was collected on an already designed proforma and analysis was done by using SPSS version 23. …”
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Not “Much Room” in the Heart: A Rare Case of a Massive Intracardiac Candida Mass by Ali Haider Jafry, Sardar Hassan Ijaz, Murtaza Mazhar, Areeba Shahnawaz, Ali Yousif

“…Since he was a poor surgical candidate, management with micafungin was initiated and continued for 8 weeks. He responded well to the regimen with resolution of the fungal mass on follow-up TTE 3 months later. …”
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