Beneficial Effects of Apple Vinegar on Hyperglycemia and Hyperlipidemia in Hypercaloric-Fed Rats by Driss Ousaaid, Hassan Laaroussi, Meryem Bakour, Asmae ElGhouizi, Abderrazak Aboulghazi, Badiaa Lyoussi, Ilham ElArabi

“…In vivo study on adult male and female Wistar rats was conducted by administering a drink containing either 10% D-glucose or water (control) for five weeks. Apple vinegar is administered daily by gavage (2 mL/kg) to rats fed D-glucose for 5 weeks. …”
Get full text

Combined Administration of Streptozotocin and Sucrose Accelerates the Appearance of Type 2 Diabetes Symptoms in Rats by Martha Isela Barragán-Bonilla, Juan Miguel Mendoza-Bello, Penélope Aguilera, Isela Parra-Rojas, Berenice Illades-Aguiar, Mónica Ramírez, Mónica Espinoza-Rojo

“…With the rats at 14 weeks of age, we determined the following: (a) fasting blood glucose, (b) oral glucose tolerance, and (c) insulin tolerance. …”
Get full text

Rapid corticosteroid taper versus standard of care for immune checkpoint inhibitor induced nephritis: a single-center retrospective cohort study by Ryan Sullivan, Riley Fadden, Kerry L Reynolds, Meghan D Lee, Harish Seethapathy, Ian A Strohbehn, Sophia H Zhao, Genevieve M Boland, Meghan E Sise

“…We aimed to compare a rapid corticosteroid taper to standard of care.Methods Retrospective cohort study in patients with ICI-induced nephritis comparing a rapid taper beginning with 60 mg/day prednisone and tapered to 10 mg within 3 weeks to a historical control group that began 60 mg/day tapered to 10 mg within 6 weeks (standard of care). …”
Get full text

Cissus quadrangularis L. hexane extract infused glyoxal cross-linked chitosan-collagen scaffold elicits early osteoinduction by Praseetha R. Nair, P.S. Unnikrishnan, Sachin J. Shenoy, G.S. Sailaja

“…The animals were sacrificed after 4 and 12 weeks to analyze the extent of new bone formation. …”
Get full text

Intermittent Preventive Treatment of Malaria in Pregnancy: Assessment of the Sulfadoxine-Pyrimethamine Three-Dose Policy on Birth Outcomes in Rural Northern Ghana by Francis Anto, Ibrahim Haruna Agongo, Victor Asoala, Elizabeth Awini, Abraham Rexford Oduro

“…Receipt of first dose of SP at 16, 17-24, and 25-36 weeks of gestation was 16.9%, 56.7%, and 26.4%, respectively. …”
Get full text

S-Adenosyl-L-Methionine Augmentation in Patients with Stage II Treatment-Resistant Major Depressive Disorder: An Open Label, Fixed Dose, Single-Blind Study by Domenico De Berardis, Stefano Marini, Nicola Serroni, Gabriella Rapini, Felice Iasevoli, Alessandro Valchera, Maria Signorelli, Eugenio Aguglia, Giampaolo Perna, Anatolia Salone, Giuseppe Di Iorio, Giovanni Martinotti, Massimo Di Giannantonio

“…Thirty-three outpatients with major depressive episode who failed to respond to at least 8 weeks of treatment with two adequate and stable doses of antidepressants were treated openly with fixed dose of SAMe (800 mg) for 8 weeks, added to existing medication. …”
Get full text

Examining the association between child development and parental mental health after preterm birth-related stress: a systematic review of the literature and meta-analysis protocol by Lotte Haverman, Cornelieke S H Aarnoudse-Moens, Joost G Daams, Gerbrich E van den Bosch, Kirsten S Muller, Celina E Henke

“…Introduction Preterm infants born before 32 weeks of gestation are generally admitted to a neonatal intensive care unit (NICU) to receive life-saving treatment, resulting in early exposure to stressful events. …”
Get full text

Evaluation of the antidiabetic and antinephritic effects of Pueraria tuberosa and Pterocarpus santalinus extracts co-encapsulated in nanostructured lipid carriers in streptozotocin... by Gyamcho Tshering Bhutia, Asit Kumar De, Manas Bhowmik, Pavia Bera, Tanmoy Bera

“…Study design: The in vivo study evaluated the therapeutic potential of NLCs loaded with hydroalcoholic extracts of P. tuberosa tubers (PTE) and P. santalinus heartwood (PSE) in managing DN over eight weeks in streptozotocin (STZ)-induced diabetic mice. …”
Get full text

Enhancing growing rabbit heat stress resilience through dietary supplementation with natural antioxidants by Ibrahim Talat El-Ratel, Aml Mekawy, Sara H.M. Hassab, Sameh Abdelnour

“…Male weaning rabbits (n = 150, 5 weeks of age) were randomly assigned to 5 groups. …”
Get full text

Physicobiochemical Characteristics and Chondrogenic Differentiation of Bone Marrow Mesenchymal Stem Cells (hBM-MSCs) in Biodegradable Porous Sponge Bovine Cartilage Scaffold by Dwikora Novembri Utomo, Ferdiansyah Mahyudin, Teddy Heri Wardhana, Purwati Purwati, Febrian Brahmana, Agrippina Waya Rahmaning Gusti

“…Biodegradability assessment used Phosphate Buffered Saline in 15, 30, 60 minutes, 6, 24, 48, 72 hours, and 1, 2 weeks. The swelling ratios were counted in 5, 10, 15, 30, 60, and 360 minutes. …”
Get full text

Timely short-term specialised palliative home care for older people with frailty and their family: a mixed-methods pilot randomised controlled trial and process evaluation by Lieve Van den Block, Kim de Nooijer, Lara Pivodic, Peter Pype, Nele Van Den Noortgate, Rose Miranda, Kim Eecloo, Stefanie De Buyser, Aurelie Joos, Katlijn Van Mulders

“…But most patients received only one visit over 8 weeks, and nurses did not organise foreseen multidisciplinary meetings, referring to absence of urgent needs. …”
Get full text

Liraglutide alleviates high-fat diet-induced kidney injury in mice by regulating the CaMKKβ/AMPK pathway by Yingli Xuan, Ting-ting Ding, Xiao-lei Mao, Shiqing Pang, Ruibin He, Li Qin, Jiang zi Yuan

“…Obesity-related nephropathy was induced in mice by continuous feeding of high-fat diet (HFD) for 12 weeks. After 12 weeks, liraglutide (0.6 mg/kg) and AMP-activated protein kinase (AMPK) agonists bortezomib (200 μg/kg) were injected for 12 weeks, respectively. …”
Get full text

Early Pregnancy Serum Metabolite Profiles Associated with Hypertensive Disorders of Pregnancy in African American Women: A Pilot Study by Erin P. Ferranti, Jennifer K. Frediani, Rebecca Mitchell, Jolyn Fernandes, Shuzhao Li, Dean P. Jones, Elizabeth Corwin, Anne L. Dunlop

“…We employed high-resolution metabolomics (HRM) to identify metabolites and metabolic pathways that were altered in early (8-14 weeks) gestation serum samples of pregnant African American women who developed HDP after 20 weeks’ gestation (n=20)—either preeclampsia (PE; n=11) or gestational hypertension (gHTN; n=9)—compared to those who delivered full term without complications (n=80). …”
Get full text

The Effective Compound Combination of Bufei Yishen Formula III Improves the Mitochondrial Dysfunction via Inhibiting JNK/Sab Pathway in COPD Mice by Song M, Han M, Zhang H, Yang Y, Tian Y, Li J, Zhao J

“…A COPD model was established using cigarette smoke and Klebsiella pneumoniae for 8 weeks. The mice in the ECC-BYF III group were treated with ECC-BYF III (7.7 mg/kg/d), and the NAC group was treated with NAC (78 mg/kg/d) for eight weeks. …”
Get full text

Double-blind, randomised, placebo-controlled trial to evaluate the effectiveness of late gestation oral melatonin supplementation in reducing induction of labour rates in nulliparo... by Miranda Davies-Tuck, Emily Callander, Mary Sharp, Scott W White, Dorota A Doherty, Jane Warland, Zoe Bradfield, Lesley Kuliukas, Monique Rose, Amber Pettitt, Kylie Ekin, JA Keelan

“…We will randomise 530 women to receive either 3 mg oral melatonin or placebo daily from 39+0 weeks’ gestation until they give birth. The primary endpoint will be IOL rate after 39 weeks post enrolment. …”
Get full text

Assessment of risk factors for osteopenia development in premature babies by A. Yu. Tsymbal, Yu. V. Kotlova

“…Results. Children born at 33 weeks or earlier are 3.23 times more likely (OR = 3.23; CI 95 % [1.08; 9.70]) to develop BT demineralization by the corresponding term of birth than other PB. …”
Get full text

Growth performance and meat quality of medium-growing chickens fed with live black soldier fly larvae by Cristina Tognoli, Sara Bellezza Oddon, Luisa Zaniboni, Ilaria Biasato, Niko Gioacchino Zeni, Manuela Renna, Laura Gasco, Stefano Paolo Marelli, Annalaura Lopez, Achille Schiavone

“…Each pen was assigned to one of dietary treatments: (1) control group (CTRL) which received a commercial chicken diet, (2) BSFL10 group which received commercial feed and live BSFL at 10% of the expected weekly feed intake and (3) BSFL20 group which received commercial feed and live BSFL at 20%. …”
Get full text

Individual physical activity preferences of adolescents in the Czech Republic and Poland: a 14-year comparative study reflecting the gender trends and prospective responses to glob... by Michal Kudlacek, Karel Fromel, Dorota Groffik, Josef Mitas

“…A positive correlation was found between the preference for running and higher levels of recreational, vigorous, and overall weekly PA. Additionally, an increased preference for running was associated with a higher likelihood of meeting weekly PA recommendations for both girls (OR = 1.82, CI = 1.62–2.04, p < 0.001) and boys (OR = 1.61, CI = 1.44–1.82, p < 0.001) in both countries. …”
Get full text

Risk Factors for Single and Multiple Recurrences for Endoscopic Retrograde Cholangiopancreatography and Open Choledochotomy in Treating Choledocholithiasis by Yao Wu, Ying Zhang, Xiao Meng Jiang, Chen Jing Xu, Yan Yan Wang, Jin Yuan Gu, Yi Li, Shun Fu Xu

“…However, the ERCP approach (EST or EPBD), OCT approach (LCBDE), primary suture, high-fat diet (postoperative), and frequency of weekly vegetable intake (< 4, postoperative) were independent risk factors for multiple recurrences of choledocholithiasis. …”
Get full text

Handshake antimicrobial stewardship for adult surgical patients by Abby Kosharek, Elizabeth Neuner, Emily Welch, Spenser January, Alice Bewley, Kevin Hsueh, Sena Sayood

“…Patients: Adults admitted to general surgery units. Intervention: Once weekly handshake antimicrobial stewardship rounds were initiated in January 2022 on adult general surgery units. …”
Get full text