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Adipokines as Drug Targets in Diabetes and Underlying Disturbances
Published 2015-01-01“…White adipose tissue is recognized as a multifactorial organ that secretes several adipose-derived factors that have been collectively termed “adipokines.” …”
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42
Mesenchymal Stem Cell-Based Immunomodulation: Properties and Clinical Application
Published 2018-01-01“…Mesenchymal stem cells (MSCs) are multipotent stem cells characterized by self-renewal, production of clonal cell populations, and multilineage differentiation. …”
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43
Octreotide Use in a Patient with MEN-1 Syndrome and Multifocal Pancreatic Neuroendocrine Tumors: A Case Report and Review of the Literature
Published 2019-01-01“…The patient tolerated octreotide therapy but self-discontinued octreotide after 24 months with a rise in PP levels off therapy. …”
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44
Comparison of Immunosuppressive and Angiogenic Properties of Human Amnion-Derived Mesenchymal Stem Cells between 2D and 3D Culture Systems
Published 2019-01-01“…The secretion of potential therapeutic factors by mesenchymal stem cells (MSCs) has aroused much interest given the benefits that it can bring in the field of regenerative medicine. …”
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45
Piperazine sulfonamides as DPP-IV inhibitors: Synthesis, induced-fit docking and in vitro biological evaluation
Published 2021-12-01“…Diabetes mellitus is a chronic illness that needs persistent medical attention and continuous patient self-management to avoid acute complications. Dipeptidyl peptidase-IV (DPP-IV) inhibitors minimize glucagon and blood glucose levels by increasing the incretin levels, glucagon-like peptide (GLP-1) and glucose-dependent insulinotropic poly-peptide (GIP), leading to insulin secretion from pancreatic beta cells. …”
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46
Assessment of Hand-Washing Knowledge and Practice among Nursing Undergraduates in Saudi Arabia
Published 2024-01-01“…In addition, most of the students washed their hands after contact with body secretions (89.5%), while 83.2% of them washed their hands before and after contact with patients. …”
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Efficiency of Stem Cell (SC) Differentiation into Insulin-Producing Cells for Treating Diabetes: a Systematic Review
Published 2021-01-01“…Stem cells are unspecialized cells with a capacity for self-renewal and differentiation into more specialized cell types. …”
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48
Administrative and Legal Principles of Interaction of Customs Posts of the State Fiscal Service of Ukraine with Other State Authorities and Citizens of Ukraine
Published 2019-12-01“…Particular attention has been paid to the peculiarities of interaction of the customs posts of the State Fiscal Service of Ukraine with local state administrations, local self-governments, the Secret Service of Ukraine and other law enforcement agencies, the State Border Guard Service of Ukraine, etc. …”
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49
Optimized scaffold-free human 3D adipose tissue organoid culture for obesity and disease modeling
Published 2025-03-01“…As adipocytes maturate and accumulate fat, they develop organotypic characteristics, increasing the buoyancy effect, which causes the organoids to oscillate, complicating culture manipulation and rendering multiple handling steps difficult.Due to these challenges, most adipose spheroid and organoid models are scaffold-based, despite many cell types' ability to secrete extracellular matrix (ECM) components and self-assemble into aggregates. …”
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50
Salivary Biomarkers (Opiorphin, Cortisol, Amylase, and IgA) Related to Age, Sex, and Stress Perception in a Prospective Cohort of Healthy Schoolchildren
Published 2021-01-01“…Levels of opiorphin (OPI), free cortisol, alpha-amylase (sAA), and secreted immunoglobulin (sIgA) were determined by quantitative assays (ELISA) in unstimulated saliva. …”
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51
Pathological Microenvironment‐Remodeling Nanoparticles to Alleviate Liver Fibrosis: Reversing Hepatocytes‐Hepatic Stellate Cells Malignant Crosstalk
Published 2025-01-01“…Abstract During the onset and malignant development of liver fibrosis, the pernicious interplay between damaged hepatocytes and activated hepatic stellate cells (HSCs) induce a self‐perpetuating vicious cycle, deteriorating fibrosis progression and posing a grave threat to public health. …”
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52
12 Weeks of Combined Endurance and Resistance Training Reduces Innate Markers of Inflammation in a Randomized Controlled Clinical Trial in Patients with Multiple Sclerosis
Published 2016-01-01“…Interestingly, the number of CD80+ pDC positively correlates with the presence of IL-10-producing regulatory type 1 cells (Tr1), an important cell type for maintaining peripheral tolerance to self-antigens. In addition, decreased production of the inflammatory mediators, TNF-α and MMP-9, upon Toll-like receptor (TLR) stimulation was found at the end of the exercise program. …”
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53
Long non-coding RNA Malat1 modulates CXCR4 expression to regulate the interaction between induced neural stem cells and microglia following closed head injury
Published 2025-01-01“…Notably, we found that TNF-α secreted by activated microglia could bind to TNFR1 at the surface of iNSCs to trigger NF-κB activation in iNSCs. …”
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54
Early precursor-derived pituitary gland tissue-resident macrophages play a pivotal role in modulating hormonal balance
Published 2025-02-01“…Microglia-like macrophages (ml-MACs) are enriched in the posterior pituitary, while other pitMØs in the anterior pituitary exhibit close interactions with hormone-secreting cells. Importantly, all pitMØs originate from early yolk sac progenitors and maintain themselves through self-renewal, independent of bone marrow-derived monocytes. …”
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Comparative Genomic Analysis of <i>Campylobacter</i> Plasmids Identified in Food Isolates
Published 2025-01-01“…Plasmids, known as important mobile genetic elements, often carry genes for antibiotic resistance, virulence, and self-mobilization. They serve as the main vectors for transferring genetic material and spreading resistance and virulence among bacteria. …”
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Microenvironment Influences on Human Umbilical Cord Mesenchymal Stem Cell-Based Bone Regeneration
Published 2021-01-01“…The isolated hUC-MSCs showed self-renewal potential and MSCs’ characteristics. …”
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57
‘Queer Reverence’: Aubrey Beardsley’s Venus and Tannhäuser
Published 2019-12-01“…Critics have read the text as an autobiographical reckoning with mortality; as authorial wish-fulfillment; as a self-reflexive satire of Decadence; as an exposé of excess; as a ‘decadent counterpublic’ that critiques nationalism; and as a parodic rewriting of Wagner that seeks to undercut his political and aesthetic legacies. …”
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Risk of SARS-CoV-2 infection among front-line healthcare workers in Northeast Brazil: a respondent-driven sampling approach
Published 2022-06-01“…Objectives We assessed the prevalence of SARS-CoV-2 infection, personal protective equipment (PPE) shortages and occurrence of biological accidents among front-line healthcare workers (HCW).Design, setting and participants Using respondent-driven sampling, the study recruited distinct categories of HCW attending suspected or confirmed patients with COVID-19 from May 2020 to February 2021, in the Recife metropolitan area, Northeast Brazil.Outcome measures The criterion to assess SARS-CoV-2 infection among HCW was a positive self-reported PCR test.Results We analysed 1525 HCW: 527 physicians, 471 registered nurses, 263 nursing assistants and 264 physical therapists. …”
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Designing a security-oriented leadership model of Mazandaran University of Medical Sciences
Published 2024-11-01“…This style of leadership can facilitate the possibility of efficient and productive intra-organizational cooperation, because in such organizations, communication flows parallel to trust. It is no secret that most of today's organizations struggle with various issues, including technological developments, resource limitations, energy problems, etc. …”
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Selected Abstracts of the 20th International Workshop on Neonatology and Pediatrics; Cagliari (Italy); October 23-26, 2024
Published 2025-01-01“…Leiner (El Paso, Texas, USA) ABS 2. L1CAM IS SECRETED THROUGH EXOSOMES IN THE DEVELOPING HUMAN BRAIN • F. …”
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