Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare by Peter Szatmari, Claire de Oliveira, Myla E Moretti, Kristin Cleverley, Lisa D Hawke, Amy H Cheung, Meaghen Quinlan-Davidson, Clement Ma, Karolin R Krause, Alina Lee, Di Shan, Katherine Tombeau Cost, Jo L Henderson

“…All MIC estimates were smaller than the smallest detectable change.Conclusions Predictive modelling offers the most precise MIC, but limited anchor credibility suggests careful anchor calibration is necessary.Clinical implications Clinicians may consider the MIC CI as indicative of meaningful change when discussing treatment impact with patients.Trial registration number NCT02836080.…”
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Extended-spectrum beta-lactamase and carbapenemase-producing Gram-negative bacteria in urinary tract infections in Ethiopia: a systematic review and meta-analysis by Mitkie Tigabie, Getnet Ayalew, Lidetu Demoze, Kebebe Tadesse, Yalewayker Gashaw, Muluneh Assefa

“…These catheters often act as reservoirs for multidrug-resistant bacteria, including extended-spectrum beta-lactamase- and carbapenemase-producing pathogens, which significantly limit treatment options and delay appropriate care. …”
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Mass Casualty Incident Training in Immersive Virtual Reality: Quasi-Experimental Evaluation of Multimethod Performance Indicators by Anke Sabine Baetzner, Yannick Hill, Benjamin Roszipal, Solène Gerwann, Matthias Beutel, Tanja Birrenbach, Markus Karlseder, Stefan Mohr, Gabriel Alexander Salg, Helmut Schrom-Feiertag, Marie Ottilie Frenkel, Cornelia Wrzus

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Daily home monitoring of potassium, creatinine, and estimated plasma volume in heart failure post‐discharge by Patrick Rossignol, Renaud Fay, Nicolas Girerd, Faiez Zannad

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Buffalo genetic improvement program in Vene- zuela by José A. Aranguren-Méndez, Rafael M. Román-Bravo, Ricardo A. Briceño-Rojas, Mauricio G. Briceño-Rojas, Luis A. Pacheco-Díaz

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HKA angle exceeding 5 degrees is strongly associated with lateral patellar translation beyond 2 mm: surgical recommendations for avoiding adverse effects on the patellofemoral join... by Zheng Jiang, Nan Zhen, Yanjie Mao, Axiang He, Han Guo, Weiming Lin, Diwen Tang, Yang Qu, Tsung-Yuan Tsai, Wanjun Liu

“…Therefore, controlling 3D-HKA may be helpful in limiting lateral patellar shift. Conclusion OWHTO changed the patellofemoral kinematics and contact patterns during stair climbing, especially the lateral patellar shift, which may lead to degeneration of the PFJ cartilage. …”
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Body Mass Index, Waist Circumference, Body Fat, Fasting Blood Glucose in a Sample of Moroccan Adolescents Aged 11–17 Years by Slimane Mehdad, Abdeslam Hamrani, Khalid El Kari, Asmaa El Hamdouchi, Amina Barakat, Mohamed El Mzibri, Najat Mokhtar, Hassan Aguenaou

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Selective arm-usage of pre-miR-1307 dysregulates angiogenesis and affects breast cancer aggressiveness by Oyku Ece Sumer, Korbinian Schelzig, Janine Jung, Xiaoya Li, Janina Moros, Luisa Schwarzmüller, Ezgi Sen, Sabine Karolus, Angelika Wörner, Verônica Rodrigues de Melo Costa, Nishanth Belugali Nataraj, Efstathios-Iason Vlachavas, Clarissa Gerhäuser, Karin Müller-Decker, Dominic Helm, Yosef Yarden, Birgitta Elisabeth Michels, Cindy Körner

“…Surprisingly, the overexpression of pre-miR-1307 in breast cancer cell lines resulted in reduced xenograft growth and impaired angiogenesis. …”
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Dynamics of retinal changes in early-stage Parkinson’s disease by Ane Murueta-Goyena, Sara Teijeira-Portas, Elisa Blanco Martín, Raquel Vázquez-Picón, Blanca Ruiz Bajo, Jone Bocos, Jorge Sánchez-Molina, Patricia Alves Dias, Ioana Croitoru, Iñaki Rodríguez Agirretxe, Rocío Del Pino, Marian Acera, Beatriz Tijero, Oihane Sáez-Atxukarro, David Romero-Bascones, Juan Carlos Gómez-Esteban, Javier Aritz Urcola, Javier Ruiz Martínez, Iñigo Gabilondo

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Estimated cumulative incidence of intervention by children's social care services to age 18: a whole-of-England administrative data cohort study using the child in need census by Matthew A Jay, Patricio Troncoso, Andy Bilson, Dave Thomson, Richard Dorsett, Rachel Pearson, Bianca De Stavola, Ruth Gilbert

“…Results Of all children living in England, before turning 18, 35.4% were referred, 32.3% were assessed, 25.3% were recorded as CiN and 6.9% were subject to a CPP (37.5%, 34.6%, 26.0% and 7.1%, respectively, in sensitivity analyses). …”
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CASC8 activates the pentose phosphate pathway to inhibit disulfidptosis in pancreatic ductal adenocarcinoma though the c-Myc-GLUT1 axis by Hong-Fei Yao, Jieqiong Ge, Jiahao Chen, Xiaoyan Tang, Chunjing Li, Xiao Hu, Abousalam Abdoulkader Ahmed, Yunlong Pu, Guihua Zhou, Tongyi Zhang, Zhiwei Cai, Chongyi Jiang

“…Protein stability, western blotting and quantitative real-time PCR assays were performed to reveal potential molecular mechanism. …”
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Prevalence of Japanese encephalitis in pigs in Mainland China during 2000–2024: a systemic review and meta-analysis by Xue-Tong Liu, Li-Dong Jiang, Yu-Ting Lin, Ran Zhao, Qi Wang, Shu-Ying Zhang, Shu-Ying Zhang, Shu-Ying Zhang, Emad Beshir Ata, Xin Liu, Yuan Wang, Zi-Xuan Liu, Cui Xu, Ying Xiao, Yi-Fan Wang, Xue Leng, Qing-Long Gong, Rui Du, Rui Du, Rui Du

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Electrochemotherapy with bleomycin, oxaliplatin, or cisplatin in mouse tumor models, from tumor ablation to in situ vaccination by Katja Uršič Valentinuzzi, Katja Uršič Valentinuzzi, Urška Kamenšek, Urška Kamenšek, Simona Kranjc Brezar, Chloe Heranney, Chloe Heranney, Tilen Komel, Tilen Komel, Simon Buček, Simon Buček, Maja Čemažar, Maja Čemažar, Gregor Serša, Gregor Serša

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Observed climate trends and farmers’ adaptation strategies in Dendi District, West Shewa Zone, Ethiopia by Busha Getachew, Gonfa Kewessa, Worku Hailu, Gezahegn Girma

“…Indigenous people need to perceive that the climate is changing or likely could change, and they need to pay sufficient attention to this perception to take action. …”
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Real‐World Study of EGFR‐TKI Rechallenge With Another TKI After First‐Line Osimertinib Discontinuation in Patients With EGFR‐Mutated Non‐Small Cell Lung Cancer: A Subset Analysis of the Reiwa Study by Kei Sonehara, Kazunari Tateishi, Kiyotaka Yoh, Kazuhiro Usui, Yukio Hosomi, Kazuma Kishi, Go Naka, Kageaki Watanabe, Shu Tamano, Kohei Uemura, Hideo Kunitoh

“…ABSTRACT Introduction First‐line osimertinib is widely used to treat patients with epidermal growth factor receptor (EGFR)‐mutated non‐small cell lung cancers (NSCLC). …”
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Dual-immunomodulatory effects on RAW264.7 macrophages and structural elucidation of a polysaccharide isolated from fermentation broth of Paecilomyces hepiali by Baoming Tian, Renjian Liu, Qi Li, Hanshan Xu, Ming Cai, Rongfa Guan, Peilong Sun, Kai Yang

“…After mRNA and protein expression analysis, toll-like receptor 4 (TLR4)/nuclear factor-κB (NF-κB) signaling pathway was discovered to play an important role in the dual-immunomodulatory effects of PHP40-2. …”
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A Randomized Trial of Insulin Glargine plus Oral Hypoglycemic Agents versus Continuous Subcutaneous Insulin Infusion to Treat Newly Diagnosed Type 2 Diabetes by Shuo Lin, Mu Chen, Wanling Chen, Keyi Lin, Panwei Mu, Bilian Zhu, Wen Xu, Manman Wang, Jianping Weng, Longyi Zeng

“…Groups A and B have comparable time to glycemic control (3.6 ± 1.2 days and 4.0 ± 1.4 days), MAGE (3.40 ± 1.40 mmol/L vs. 3.16 ± 1.38 mmol/L; p=0.484), and 24-hour mean blood glucose (7.49 ± 0.96 mmol/L vs. 7.02 ± 1.03 mmol/L). …”
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Translation and Validation of the Edinburgh Postnatal Depression Scale for Eritrea: A Screening Tool for Postpartum Depression in Primary Health Care Facilities by Gebregziabher NK, Netsereab TB, Alazar FA, Fessaha YG, Sium AH, Ghebrehiwet NK

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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…This still represents a significant societal burden and these findings may help inform public health initiatives to encourage prevention and evidence‐based interventional strategies and ultimately, improve the quality of life for those suffering with SP in Wales.…”
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Association of social frailty, sarcopenia, and oral frailty with depressive symptoms in Chinese older adults: a cross-sectional study by Yuanhao Sun, Huan Liu, Xiangdong Li, Lin Zhang, Wenwen Xu, Hairong liu, Ting Yuan

“…This will help to improve the quality of life and mental health.…”
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