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Efficacy and safety of SHEN26, a novel oral small molecular RdRp inhibitor for COVID-19 treatment: a multicenter, randomized, double-blinded, placebo-controlled, phase II clinical...
Published 2025-01-01“…No significant difference was found in the viral clearance time between SHEN26 administrating groups and placebo groups. …”
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A new signature associated with anoikis predicts the outcome and immune infiltration in nasopharyngeal carcinoma
Published 2025-02-01“…Key gene expression levels were validated through real-time PCR and immunohistochemical staining. Results Three differentially expressed ARGs (CDC25C, E2F1 and RBL2) with prognostic value were identified by the intersection of multiple machine learning algorithms. …”
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Comparative Lipid-Lowering/Increasing Efficacy of 7 Statins in Patients with Dyslipidemia, Cardiovascular Diseases, or Diabetes Mellitus: Systematic Review and Network Meta-Analyse...
Published 2020-01-01“…The results should be interpreted with caution due to some limitations in our review. However, they can provide references and evidence-based foundation for drug selection in both statin monotherapies and statin combination therapies.…”
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Survey of nutritional intake status in college baseball players
Published 2025-12-01“…The survey items included basic characteristics such as college grade and type of living arrangement, and information on living conditions, e.g. whether the participant ate breakfast. …”
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Military-Applied Means of Physical Education in Pre-University Educational Institutions of the Russian Ministry of Defence
Published 2019-07-01“…The analysis of students’ questionnaires before and after the experiment revealed strengthening of students’ moral stability, growing interest in military science and motivation to studying of an applied training material, as well as significant increase in the number of applicants seeking to continue their training in higher educational institutions of the Ministry of Defence of the Russian Federation and to dedicate their lives to military service. The proposals and practical recommendations on purposeful introduction of complexes of specialised physical exercises and elements of disciplines of military-applied sports to educational process are formulated.Practical significance. …”
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Risk of SARS-CoV-2 infection before and after the Omicron wave in a cohort of healthcare workers in Ontario, Canada
Published 2025-02-01“…Abstract Background Longitudinal healthcare worker (HCW) cohorts throughout the COVID-19 pandemic provide a unique opportunity to study the relative contributions of various exposures to infection risk over time. This study aimed to examine how demographic, health, occupational, household and community factors influenced the SARS-CoV-2 infection risk in a cohort of HCWs in Southeastern Ontario, Canada, during the early pandemic and the Omicron waves. …”
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Le port antique de Chelles (Seine-et-Marne) : une course après la rivière
Published 2020-12-01“…Archaeological and geoarchaeological data document the efforts made to maintain the riverbank, making it possible to reconstruct its evolution over time. The study of the remains of this port has identified four distinct developmental phases.…”
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Effect of different diets on the fatty acid compo- sition of buffalo bulk milk
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The application of Vavilov’s approaches to the phylogeny and evolution of cultivated species of the genus <i>Avena</i> L.
Published 2023-12-01“…It was established that the tetraploid cultivated species A. abyssinica had most likely originated from the wild A. vaviloviana. An analysis of the ways of A. sativa and A. byzantina domestication showed that the most widespread ribotype of the A. sativa hexaploid was inherited from A. ludoviciana, and the second most widespread one, from A. magna, while A. byzantina has two unique ribotype families, most likely inherited from an extinct oat species or a still undiscovered cryptospecies.…”
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hUC-MSC preserves erectile function by restoring mitochondrial mass of penile smooth muscle cells in a rat model of cavernous nerve injury via SIRT1/PGC-1a/TFAM signaling
Published 2025-01-01“…Abstract Background Cavernous nerve injury-induced erectile dysfunction (CNI-ED) is a common complication following radical prostatectomy and severely affects patients’ quality of life. The mitochondrial impairment in corpus cavernosum smooth muscle cells (CCSMCs) may be an important pathological mechanism of CNI-ED. …”
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Comparative evaluation of antifungal susceptibility testing methods of invasive Candida species and detection of FKS genes mutations in caspofungin intermediate and resistant isola...
Published 2025-01-01“…Abstract Background Fungal invasive infections caused by Candida species pose a substantial public health risk with limited therapeutic options. Antifungal susceptibility testing (AFST) is necessary to optimize the therapy. …”
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